CA2462646C - Adjuvanted meningococcus compositions - Google Patents
Adjuvanted meningococcus compositions Download PDFInfo
- Publication number
- CA2462646C CA2462646C CA2462646A CA2462646A CA2462646C CA 2462646 C CA2462646 C CA 2462646C CA 2462646 A CA2462646 A CA 2462646A CA 2462646 A CA2462646 A CA 2462646A CA 2462646 C CA2462646 C CA 2462646C
- Authority
- CA
- Canada
- Prior art keywords
- composition
- antigen
- microparticles
- plg
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Biological Depolymerization Polymers (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32692901P | 2001-10-03 | 2001-10-03 | |
US60/326,929 | 2001-10-03 | ||
USPCT/US02/10869 | 2002-04-05 | ||
PCT/US2002/010869 WO2002080648A2 (en) | 2001-04-05 | 2002-04-05 | Mucosal boosting following parenteral priming |
US37354702P | 2002-04-17 | 2002-04-17 | |
US60/373,547 | 2002-04-17 | ||
US38067702P | 2002-05-13 | 2002-05-13 | |
US60/380,677 | 2002-05-13 | ||
US25443802A | 2002-09-24 | 2002-09-24 | |
USPCT/US02/30423 | 2002-09-24 | ||
US0230423 | 2002-09-24 | ||
US10/254,438 | 2002-09-24 | ||
USPCT/US02/31486 | 2002-10-03 | ||
PCT/US2002/031726 WO2003028661A2 (en) | 2001-10-03 | 2002-10-03 | Adjuvanted meningococcus compositions |
US10/265,083 | 2002-10-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2462646A1 CA2462646A1 (en) | 2003-04-10 |
CA2462646C true CA2462646C (en) | 2013-02-12 |
Family
ID=32601151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2462646A Expired - Fee Related CA2462646C (en) | 2001-10-03 | 2002-10-03 | Adjuvanted meningococcus compositions |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1438323A4 (pt) |
JP (1) | JP4522699B2 (pt) |
CN (1) | CN100354297C (pt) |
AU (1) | AU2002334844B2 (pt) |
BR (1) | BR0213119A (pt) |
CA (1) | CA2462646C (pt) |
NZ (1) | NZ532274A (pt) |
WO (1) | WO2003028661A2 (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
GB0302218D0 (en) * | 2003-01-30 | 2003-03-05 | Chiron Sri | Vaccine formulation & Mucosal delivery |
MXPA04011249A (es) * | 2002-05-14 | 2005-06-06 | Chiron Srl | Vacunas mucosales con adyuvante de quitosano y antigenos meningococicos. |
KR101239242B1 (ko) * | 2002-08-02 | 2013-03-11 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 항원 조합물을 포함하는 나이세리아 백신 조성물 |
JP2006520746A (ja) | 2002-12-27 | 2006-09-14 | カイロン コーポレイション | リン脂質を含む免疫原性組成物 |
WO2004067030A2 (en) * | 2003-01-30 | 2004-08-12 | Chiron Srl | Injectable vaccines against multiple meningococcal serogroups |
DE602004020189D1 (de) * | 2003-01-30 | 2009-05-07 | Novartis Vaccines & Diagnostic | Adjuvante influenza-vakzine |
US7731967B2 (en) * | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
PL1631264T5 (pl) | 2003-06-02 | 2018-09-28 | Glaxosmithkline Biologicals Sa | Kompozycje immunogenne oparte na biodegradowalnych mikrocząstkach zawierających toksoid błonicy i tężca |
WO2005081847A2 (en) * | 2004-02-20 | 2005-09-09 | Hybridon, Inc. | Potent mucosal immune response induced by modified immunomodulatory oligonucleotides |
US9107813B2 (en) | 2004-11-15 | 2015-08-18 | Derek T. O'Hagan | Immunogenic compositions containing anthrax antigen, biodegradable polymer microparticles, and polynucleotide-containing immunological adjuvant |
BRPI0607254A2 (pt) | 2005-01-28 | 2009-08-25 | Susan Szathmary | composições imunologicamente ativa, método in vitro para identificação de peptìdeo ou proteìna, uso da composição e célula dendrìtica |
JP2008531672A (ja) * | 2005-03-02 | 2008-08-14 | イギリス国 | 医薬組成物 |
AU2008335457B2 (en) | 2007-12-07 | 2015-04-16 | Glaxosmithkline Biologicals S.A. | Compositions for inducing immune responses |
CN101559225B (zh) * | 2008-04-18 | 2012-07-11 | 北京生物制品研究所 | 脑膜炎球菌疫苗 |
RU2669346C2 (ru) | 2012-06-21 | 2018-10-10 | Норсвестерн Юниверсити | Частицы, конъюгированные с пептидами |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6239116B1 (en) * | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
CA2308606A1 (en) * | 1997-11-06 | 1999-05-20 | Chiron S.P.A. | Neisserial antigens |
AU1979599A (en) * | 1998-01-14 | 1999-08-02 | Chiron S.P.A. | (neisseria meningitidis) antigens |
BR9910089A (pt) * | 1998-05-01 | 2004-06-08 | Chiron Corp | Composições e antìgenos de neisseria meningitidis |
DE69930642T2 (de) * | 1998-07-29 | 2006-12-28 | Chiron Corp., Emeryville | Mikropartikel mit adsorbenten oberflächen, verfahren zu ihrer herstellung und ihrer verwendung |
JP2004511201A (ja) * | 1998-10-09 | 2004-04-15 | カイロン コーポレイション | ナイセリアゲノム配列およびそれらの使用方法 |
EP1574210B1 (en) * | 1999-02-26 | 2016-04-06 | Novartis Vaccines and Diagnostics, Inc. | Microemulsions with adsorbed macromolecules |
US8221761B1 (en) * | 1999-02-26 | 2012-07-17 | Novartis Ag | Enhancement of bactericidal activity of neisseria antigens with oligonucleotides containing CG motifs |
RU2245366C2 (ru) * | 1999-04-30 | 2005-01-27 | Чирон С.Р.Л. | Антиген neisseria, кодирующая его нуклеиновая кислота, их использование |
PT2270030E (pt) * | 2000-02-28 | 2012-07-24 | Novartis Vaccines & Diagnostic | Expressão heteróloga de proteínas de neisseria |
-
2002
- 2002-10-03 EP EP02800481A patent/EP1438323A4/en not_active Withdrawn
- 2002-10-03 AU AU2002334844A patent/AU2002334844B2/en not_active Ceased
- 2002-10-03 CA CA2462646A patent/CA2462646C/en not_active Expired - Fee Related
- 2002-10-03 WO PCT/US2002/031726 patent/WO2003028661A2/en active IP Right Grant
- 2002-10-03 NZ NZ532274A patent/NZ532274A/en not_active IP Right Cessation
- 2002-10-03 BR BR0213119-6A patent/BR0213119A/pt not_active IP Right Cessation
- 2002-10-03 CN CNB028241282A patent/CN100354297C/zh not_active Expired - Fee Related
- 2002-10-03 JP JP2003531997A patent/JP4522699B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1438323A2 (en) | 2004-07-21 |
AU2002334844B8 (en) | 2003-04-14 |
BR0213119A (pt) | 2004-12-28 |
JP4522699B2 (ja) | 2010-08-11 |
AU2002334844B2 (en) | 2007-08-02 |
JP2005526697A (ja) | 2005-09-08 |
CN1599746A (zh) | 2005-03-23 |
WO2003028661A2 (en) | 2003-04-10 |
NZ532274A (en) | 2006-02-24 |
EP1438323A4 (en) | 2007-08-01 |
CN100354297C (zh) | 2007-12-12 |
CA2462646A1 (en) | 2003-04-10 |
WO2003028661A3 (en) | 2003-10-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20141003 |