CU20170145A7 - Métodos para tratar infecciones por el virus filoviridae - Google Patents
Métodos para tratar infecciones por el virus filoviridaeInfo
- Publication number
- CU20170145A7 CU20170145A7 CUP2017000145A CU20170145A CU20170145A7 CU 20170145 A7 CU20170145 A7 CU 20170145A7 CU P2017000145 A CUP2017000145 A CU P2017000145A CU 20170145 A CU20170145 A CU 20170145A CU 20170145 A7 CU20170145 A7 CU 20170145A7
- Authority
- CU
- Cuba
- Prior art keywords
- methods
- virus
- treat infections
- filoviridae
- infections
- Prior art date
Links
- 241000711950 Filoviridae Species 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241001115402 Ebolavirus Species 0.000 abstract 1
- 241001115401 Marburgvirus Species 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 235000021317 phosphate Nutrition 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- -1 riboside phosphates Chemical class 0.000 abstract 1
- 150000008223 ribosides Chemical class 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
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- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462072331P | 2014-10-29 | 2014-10-29 | |
US201562105619P | 2015-01-20 | 2015-01-20 | |
PCT/US2015/057933 WO2016069826A1 (en) | 2014-10-29 | 2015-10-29 | Methods for treating filoviridae virus infections |
Publications (1)
Publication Number | Publication Date |
---|---|
CU20170145A7 true CU20170145A7 (es) | 2018-07-05 |
Family
ID=54557474
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CUP2017000145A CU20170145A7 (es) | 2014-10-29 | 2015-10-29 | Métodos para tratar infecciones por el virus filoviridae |
CUP2017000056A CU20170056A7 (es) | 2014-10-29 | 2015-10-29 | Métodos para tratar infecciones por el virus filoviridae |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CUP2017000056A CU20170056A7 (es) | 2014-10-29 | 2015-10-29 | Métodos para tratar infecciones por el virus filoviridae |
Country Status (45)
Families Citing this family (107)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011035250A1 (en) | 2009-09-21 | 2011-03-24 | Gilead Sciences, Inc. | Processes and intermediates for the preparation of 1'-substituted carba-nucleoside analogs |
PL2595980T3 (pl) | 2010-07-22 | 2015-03-31 | Gilead Sciences Inc | Sposoby i związki do leczenia infekcji wirusowych Paramyxoviridae |
TWI687432B (zh) * | 2014-10-29 | 2020-03-11 | 美商基利科學股份有限公司 | 絲狀病毒科病毒感染之治療 |
ES2918585T3 (es) | 2015-09-16 | 2022-07-19 | Gilead Sciences Inc | Métodos para el tratamiento de infecciones por el virus Arenaviridae |
US11617753B2 (en) | 2016-11-10 | 2023-04-04 | Oyagen, Inc. | Methods of treating and inhibiting Ebola virus infection |
CN110198947A (zh) * | 2016-11-18 | 2019-09-03 | 纽维制药有限公司 | 线粒体质子离子载体的肝前药 |
EP3595672B1 (en) * | 2017-03-14 | 2023-09-06 | Gilead Sciences, Inc. | Compounds for use in methods of treating feline coronavirus infections |
JP6923112B2 (ja) * | 2017-03-31 | 2021-08-18 | 国立大学法人北海道大学 | フィロウイルスの細胞侵入阻害活性を有するビアリールスルフォンアミド誘導体 |
ES2938859T3 (es) | 2017-05-01 | 2023-04-17 | Gilead Sciences Inc | Una forma cristalina de (S)-2-etilbutilo 2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopirrolo[2,1-f][1,2,4]triazin-7-il)-5-ciano-3,4-dihidroxitetrahidrofuran-2-il)metoxi)(fenoxi)fosforil)amino)propanoato |
EP3651734A1 (en) | 2017-07-11 | 2020-05-20 | Gilead Sciences, Inc. | Compositions comprising an rna polymerase inhibitor and cyclodextrin for treating viral infections |
MA50172A (fr) | 2017-09-18 | 2021-04-07 | Janssen Biopharma Inc | Nucléosides substitués, nucléotides et analogues de ceux-ci |
CN109535200A (zh) * | 2017-09-21 | 2019-03-29 | 杭州和正医药有限公司 | 一种核苷类似物的磷酰胺酯前药、药物组合物及其应用 |
CN109748944B (zh) * | 2017-11-03 | 2021-12-10 | 中国科学院上海药物研究所 | 5’-脱氧-5’-异丙基取代氨基核苷类化合物、其制备方法和用途 |
CN109748943A (zh) * | 2017-11-03 | 2019-05-14 | 中国科学院上海药物研究所 | 2’-c-甲基取代核苷类化合物及其制备与用途 |
CN110330540A (zh) * | 2019-08-08 | 2019-10-15 | 木天(济南)生物科技有限公司 | 核苷盐及其制备方法 |
CN110613726B (zh) * | 2019-09-25 | 2020-10-16 | 广州六顺生物科技股份有限公司 | 核苷化合物的应用 |
WO2021095091A1 (ja) * | 2019-11-11 | 2021-05-20 | 藤本化学製品株式会社 | アミノアリール誘導体及びその中間体、並びにそれらの製造方法 |
CN110776512A (zh) * | 2019-11-28 | 2020-02-11 | 成都傲飞生物化学品有限责任公司 | 一种核苷类似物的制备方法 |
JP2023512656A (ja) | 2020-01-27 | 2023-03-28 | ギリアード サイエンシーズ, インコーポレイテッド | SARS CoV-2感染を治療するための方法 |
US11738025B2 (en) | 2020-02-04 | 2023-08-29 | Oyagen, Inc. | Method for treating coronavirus infections |
CN113214263B (zh) * | 2020-02-06 | 2022-09-30 | 北京桦冠医药科技有限公司 | 瑞德西韦关键中间体的一种合成方法 |
US20210244705A1 (en) * | 2020-02-07 | 2021-08-12 | Centre For Digestive Diseases | Therapeutic compositions, products of manufacture and methods for ameliorating or preventing coronavirus infection |
CN111205327B (zh) * | 2020-02-17 | 2022-05-31 | 南京法恩化学有限公司 | 一种瑞德西韦的制备方法 |
TW202322824A (zh) | 2020-02-18 | 2023-06-16 | 美商基利科學股份有限公司 | 抗病毒化合物 |
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