CS199680B2 - Method of producing novel bis/3,5-dicarbamoyl-2,4,6-triiodanilide/dicarboxylic acids - Google Patents
Method of producing novel bis/3,5-dicarbamoyl-2,4,6-triiodanilide/dicarboxylic acids Download PDFInfo
- Publication number
- CS199680B2 CS199680B2 CS774059A CS405977A CS199680B2 CS 199680 B2 CS199680 B2 CS 199680B2 CS 774059 A CS774059 A CS 774059A CS 405977 A CS405977 A CS 405977A CS 199680 B2 CS199680 B2 CS 199680B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- bis
- acid
- formula
- triiodanilide
- solution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2628517A DE2628517C2 (de) | 1976-06-23 | 1976-06-23 | Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS199680B2 true CS199680B2 (en) | 1980-07-31 |
Family
ID=5981407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS774059A CS199680B2 (en) | 1976-06-23 | 1977-06-20 | Method of producing novel bis/3,5-dicarbamoyl-2,4,6-triiodanilide/dicarboxylic acids |
Country Status (28)
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH626873A5 (US06582424-20030624-M00016.png) * | 1977-03-28 | 1981-12-15 | Bracco Ind Chimica Spa | |
| DK273280A (da) * | 1979-06-28 | 1980-12-29 | Schering Ag | Trijoderede 5-aminoisophthalsyrederivater |
| IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
| IT1207226B (it) * | 1979-08-09 | 1989-05-17 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono. |
| JPS56127373A (en) * | 1980-01-31 | 1981-10-06 | Univ California | Novel amino-dioxepane intermediate for synthesizing novel nonionic contrast agent |
| US4341756A (en) * | 1980-01-31 | 1982-07-27 | The Regents Of The University Of California | Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media |
| DE3038853A1 (de) * | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii) |
| NO161368C (no) * | 1982-11-08 | 1989-08-09 | Nyegaard & Co As | Roentgenkontrastmidler samt radiologiske preparater derav. |
| FR2541272A1 (fr) * | 1983-02-23 | 1984-08-24 | Guerbet Sa | Composes bromes et produits opacifiants en contenant |
| US4650903A (en) * | 1984-06-21 | 1987-03-17 | The Bf Goodrich Company | Oligomeric amides as synergists for antioxidants and UV stabilizers |
| DE3731542A1 (de) * | 1987-09-17 | 1989-03-30 | Schering Ag | Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
| DE3739098A1 (de) * | 1987-11-16 | 1989-05-24 | Schering Ag | Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
| US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
| IT1252180B (it) * | 1991-12-10 | 1995-06-05 | Bracco Ind Chimica Spa | 5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono |
| CN1038725C (zh) * | 1993-12-04 | 1998-06-17 | 吉林省鹊源国际生物工程有限公司 | 复方天然香菇营养液 |
| US6149891A (en) * | 1995-05-31 | 2000-11-21 | Israel Humanitarian Foundation Ltd. | X-ray contrast medium and method for protecting against harmful effects thereof |
| IT1299202B1 (it) * | 1998-05-08 | 2000-02-29 | Dibra Spa | Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo |
| US7790141B2 (en) * | 2003-08-11 | 2010-09-07 | Pathak Holdings, Llc | Radio-opaque compounds, compositions containing same and methods of their synthesis and use |
| JP5340281B2 (ja) | 2007-07-12 | 2013-11-13 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 造影剤 |
| ES2389975T3 (es) | 2007-10-12 | 2012-11-05 | Ge Healthcare As | Agentes de contraste |
| JP2011500533A (ja) | 2007-10-12 | 2011-01-06 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 造影剤 |
| WO2009047315A1 (en) | 2007-10-12 | 2009-04-16 | Ge Healthcare As | Contrast agents |
| JP2011500531A (ja) | 2007-10-12 | 2011-01-06 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 造影剤 |
| US8551449B2 (en) * | 2007-10-30 | 2013-10-08 | Ge Healthcare As | Contrast agents |
| JP2011509943A (ja) * | 2008-01-14 | 2011-03-31 | マリンクロッド・インコーポレイテッド | イオシメノールを調製するためのプロセス |
| WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
| CN115501172A (zh) | 2014-11-21 | 2022-12-23 | 丹麦技术大学 | 用于局部药物释放的凝胶制剂 |
| US11058780B2 (en) | 2016-05-20 | 2021-07-13 | Technical University Of Denmark | Palpable marker composition |
| US20220339285A1 (en) | 2019-06-12 | 2022-10-27 | Technical University Of Denmark | Dissacharide formulations for controlled drug release |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2853424A (en) * | 1952-08-06 | 1958-09-23 | Schering Ag | X-ray contrast agents comprising symmetrical bifunctional analogs of nu-acyl derivatives of 2, 4, 6 triiodo-3-amino benzoic acid |
| US3178473A (en) * | 1962-03-02 | 1965-04-13 | Nyegaard & Co As | Process for the n-alkylation of acyl anilides halogen substituted in the nucleus |
| US3290366A (en) * | 1963-03-06 | 1966-12-06 | Mallinckrodt Chemical Works | 5-amino-nu-alkyl-2, 4, 6-triiodoisophthalamic acid derivatives |
| GB1033777A (en) * | 1963-06-06 | 1966-06-22 | Sterling Drug Inc | Bis-anilide derivatives |
| US3732293A (en) * | 1968-03-15 | 1973-05-08 | Sterling Drug Inc | Iodinated bis(aminobenzoic acids) and esters thereof |
| CH502104A (de) * | 1968-05-02 | 1971-01-31 | Bracco Ind Chimica Spa | Neue Röntgenkontrastmittel und Verfahren zu ihrer Herstellung |
| IL34803A (en) * | 1969-06-27 | 1975-03-13 | Nyegaard & Co As | N-hydroxyalkyl substituted benzamides and iodo methanesulfonamide and radiological compositions containing them |
| US3660464A (en) * | 1970-06-19 | 1972-05-02 | Squibb & Sons Inc | Tri-iodinated diaminobenzoic acid derivatives |
| BE787669A (fr) * | 1971-08-17 | 1973-02-19 | Schering Ag | Anilides d'acide n-methyl-dicarboxylique triiodes, et leur procede de preparation |
| DD104193A5 (US06582424-20030624-M00016.png) * | 1972-12-22 | 1974-03-05 | ||
| DE2629228C2 (de) * | 1976-06-25 | 1984-10-18 | Schering AG, 1000 Berlin und 4709 Bergkamen | Jodierte Isophthalamsäure-Derivate Verfahren zu deren Herstellung sowie deren Verwendung |
| CH626873A5 (US06582424-20030624-M00016.png) * | 1977-03-28 | 1981-12-15 | Bracco Ind Chimica Spa |
-
1976
- 1976-06-23 DE DE2628517A patent/DE2628517C2/de not_active Expired
-
1977
- 1977-05-18 NL NLAANVRAGE7705509,A patent/NL189510C/xx not_active IP Right Cessation
- 1977-06-16 FI FI771900A patent/FI67540C/fi not_active IP Right Cessation
- 1977-06-16 DK DK266177A patent/DK150505C/da not_active IP Right Cessation
- 1977-06-20 GB GB7222/80A patent/GB1588734A/en not_active Expired
- 1977-06-20 GB GB25644/77A patent/GB1588733A/en not_active Expired
- 1977-06-20 PL PL1977199019A patent/PL108102B1/pl not_active IP Right Cessation
- 1977-06-20 CS CS774059A patent/CS199680B2/cs unknown
- 1977-06-20 IE IE1249/77A patent/IE45225B1/en not_active IP Right Cessation
- 1977-06-21 IL IL52356A patent/IL52356A/xx unknown
- 1977-06-21 CH CH761277A patent/CH629751A5/de not_active IP Right Cessation
- 1977-06-21 PT PT66690A patent/PT66690B/pt unknown
- 1977-06-21 DD DD7700199616A patent/DD131014A5/xx unknown
- 1977-06-21 GR GR53760A patent/GR71696B/el unknown
- 1977-06-21 LU LU77588A patent/LU77588A1/xx unknown
- 1977-06-22 SU SU772498151A patent/SU917696A3/ru active
- 1977-06-22 AU AU26325/77A patent/AU512304B2/en not_active Expired
- 1977-06-22 ES ES460007A patent/ES460007A1/es not_active Expired
- 1977-06-22 SE SE7707230A patent/SE436871B/xx not_active IP Right Cessation
- 1977-06-22 NO NO772202A patent/NO147447C/no unknown
- 1977-06-22 HU HU77SCHE611A patent/HU174228B/hu unknown
- 1977-06-22 CA CA281,184A patent/CA1106400A/en not_active Expired
- 1977-06-23 JP JP7489777A patent/JPS537637A/ja active Granted
- 1977-06-23 BE BE178719A patent/BE856039A/xx not_active IP Right Cessation
- 1977-06-23 ZA ZA00773782A patent/ZA773782B/xx unknown
- 1977-06-23 FR FR7719234A patent/FR2355808A1/fr active Granted
- 1977-06-23 IT IT7724994A patent/IT1237314B/it active
- 1977-06-23 AT AT443777A patent/AT361117B/de not_active IP Right Cessation
-
1979
- 1979-01-12 US US06/002,901 patent/US4239747A/en not_active Expired - Lifetime
-
1980
- 1980-03-21 CA CA348,166A patent/CA1106401A/en not_active Expired
- 1980-06-18 IL IL60344A patent/IL60344A0/xx unknown
-
1981
- 1981-10-08 IE IE2351/81A patent/IE45226B1/en not_active IP Right Cessation
-
1982
- 1982-08-04 NO NO822674A patent/NO148811C/no unknown
-
1984
- 1984-12-12 DK DK595284A patent/DK165973C/da not_active IP Right Cessation
-
1985
- 1985-07-09 JP JP60149408A patent/JPS61126059A/ja active Granted
-
1993
- 1993-06-09 LU LU88292C patent/LU88292I2/de unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CS199680B2 (en) | Method of producing novel bis/3,5-dicarbamoyl-2,4,6-triiodanilide/dicarboxylic acids | |
| JP3949714B2 (ja) | 肝臓胆管不磁気共鳴コントラスト剤 | |
| US5885548A (en) | Multiply substituted DTPA derivatives and their metal complexes, and their metal complexes, pharmaceutical agents that contain these complexes, their use in diagnosis and therapy, as well as process for the production of pharmaceutical agents | |
| JP2569144B2 (ja) | 新規ジカルボン酸ービス（３，５ージカルバモイルー２，４，６ートリヨードーアニリド）、その製法及びこれを含有するレントゲン造影剤 | |
| JPS63119446A (ja) | ポリ−（酸−アルキレン−アミノ）−アルカンの常磁性多価金属塩 | |
| JPH05503072A (ja) | 診断用ｎｍｒ映像化の為のヒドロキシ―アリール金属キレート | |
| JPH0222066B2 (US06582424-20030624-M00016.png) | ||
| US5409689A (en) | MRI image enhancement using complexes of paramagnetic cations and amine ligands containing a mixture of phosphonate and non-phosphonate pendant arms | |
| IT9022088A1 (it) | 1, 3-bis(3-(mono o poliidrossi)acilamino-5-(mono o poliidrossi-alchil) aminocarbonil-2, 4, 6-triiodo-benzoil-amino)-idrossi- o idrossi-alchilpropani, loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono | |
| JPS6313428B2 (US06582424-20030624-M00016.png) | ||
| EP0805815A1 (en) | Bismuth compounds | |
| US5019371A (en) | Novel x-ray contrast agents, compositions and methods | |
| JP3249112B2 (ja) | 非イオン性化合物及び該化合物を含有する放射線造影剤組成物 | |
| IE64759B1 (en) | New substituted dicarboxylic acid-bis (3,5-dicarbamoyl-2,4,6-triiodoanilides) process for their production as well as x-ray contrast media containing them | |
| CA1339666C (en) | Non-ionic polyol contrast media from ionic contrast media | |
| US5616312A (en) | Thiol ligands and complexes for X-ray imaging | |
| EP0716091B1 (en) | Tris(substituted phenyl)bismuth derivative | |
| US5035877A (en) | Non-ionic contrast media from ionic contrast media | |
| JPH0374211B2 (US06582424-20030624-M00016.png) | ||
| US3781338A (en) | Nitrilotriacyltriimino-tris-(2,4,6-triiodobenzoic acid)compounds | |
| JPH09505833A (ja) | Ｘ線放射線医学における造影剤としてのヨウ素化誘導体、それらの製造および用途 | |
| JP2807852B2 (ja) | 新規キレート化剤、該キレート化剤と金属原子との錯化合物及びそれを含む診断剤 | |
| US20080267884A1 (en) | Contrast Agents and Diagnostic Compositions Based on Iodine-Containing Cyanuric Acid Derivatives | |
| FI58589B (fi) | Roentgenkontrastmedel innehaollande 3,6,9-trioxiundekan-1,11-dioyl-bis-(3-karboxi-2,4,6-trijod-anilid) eller salt daerav och foerfarande foer framstaellning av detta | |
| JPH029584B2 (US06582424-20030624-M00016.png) |
