IL52356A - Dicarboxylic acid bis-(3,5-dicarbamoyl-2,4,6-triiodoanilides),their preparation and x-ray contrast preparations comprising them - Google Patents
Dicarboxylic acid bis-(3,5-dicarbamoyl-2,4,6-triiodoanilides),their preparation and x-ray contrast preparations comprising themInfo
- Publication number
- IL52356A IL52356A IL52356A IL5235677A IL52356A IL 52356 A IL52356 A IL 52356A IL 52356 A IL52356 A IL 52356A IL 5235677 A IL5235677 A IL 5235677A IL 52356 A IL52356 A IL 52356A
- Authority
- IL
- Israel
- Prior art keywords
- triiodoanilides
- dicarbamoyl
- preparation
- dicarboxylic acid
- acid bis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polyesters Or Polycarbonates (AREA)
- Medicinal Preparation (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL60344A IL60344A (en) | 1976-06-23 | 1977-06-21 | Tetracarboxylic acid tetrachlorides and a process for the preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2628517A DE2628517C2 (de) | 1976-06-23 | 1976-06-23 | Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel |
Publications (2)
Publication Number | Publication Date |
---|---|
IL52356A0 IL52356A0 (en) | 1977-08-31 |
IL52356A true IL52356A (en) | 1981-03-31 |
Family
ID=5981407
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL52356A IL52356A (en) | 1976-06-23 | 1977-06-21 | Dicarboxylic acid bis-(3,5-dicarbamoyl-2,4,6-triiodoanilides),their preparation and x-ray contrast preparations comprising them |
IL60344A IL60344A0 (en) | 1976-06-23 | 1980-06-18 | New tetracarboxylic acid tetrachlorides and a process for the preparation thereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL60344A IL60344A0 (en) | 1976-06-23 | 1980-06-18 | New tetracarboxylic acid tetrachlorides and a process for the preparation thereof |
Country Status (28)
Country | Link |
---|---|
US (1) | US4239747A (xx) |
JP (2) | JPS537637A (xx) |
AT (1) | AT361117B (xx) |
AU (1) | AU512304B2 (xx) |
BE (1) | BE856039A (xx) |
CA (2) | CA1106400A (xx) |
CH (1) | CH629751A5 (xx) |
CS (1) | CS199680B2 (xx) |
DD (1) | DD131014A5 (xx) |
DE (1) | DE2628517C2 (xx) |
DK (2) | DK150505C (xx) |
ES (1) | ES460007A1 (xx) |
FI (1) | FI67540C (xx) |
FR (1) | FR2355808A1 (xx) |
GB (2) | GB1588733A (xx) |
GR (1) | GR71696B (xx) |
HU (1) | HU174228B (xx) |
IE (2) | IE45225B1 (xx) |
IL (2) | IL52356A (xx) |
IT (1) | IT1237314B (xx) |
LU (2) | LU77588A1 (xx) |
NL (1) | NL189510C (xx) |
NO (2) | NO147447C (xx) |
PL (1) | PL108102B1 (xx) |
PT (1) | PT66690B (xx) |
SE (1) | SE436871B (xx) |
SU (1) | SU917696A3 (xx) |
ZA (1) | ZA773782B (xx) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH626873A5 (xx) * | 1977-03-28 | 1981-12-15 | Bracco Ind Chimica Spa | |
DK273280A (da) * | 1979-06-28 | 1980-12-29 | Schering Ag | Trijoderede 5-aminoisophthalsyrederivater |
IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
IT1207226B (it) * | 1979-08-09 | 1989-05-17 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono. |
JPS56127373A (en) * | 1980-01-31 | 1981-10-06 | Univ California | Novel amino-dioxepane intermediate for synthesizing novel nonionic contrast agent |
US4341756A (en) * | 1980-01-31 | 1982-07-27 | The Regents Of The University Of California | Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media |
DE3038853A1 (de) * | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii) |
EP0108638B1 (en) * | 1982-11-08 | 1986-07-16 | NYEGAARD & CO. A/S | X-ray contrast agents |
FR2541272A1 (fr) * | 1983-02-23 | 1984-08-24 | Guerbet Sa | Composes bromes et produits opacifiants en contenant |
US4650903A (en) * | 1984-06-21 | 1987-03-17 | The Bf Goodrich Company | Oligomeric amides as synergists for antioxidants and UV stabilizers |
DE3731542A1 (de) * | 1987-09-17 | 1989-03-30 | Schering Ag | Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
DE3739098A1 (de) * | 1987-11-16 | 1989-05-24 | Schering Ag | Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
IT1252180B (it) * | 1991-12-10 | 1995-06-05 | Bracco Ind Chimica Spa | 5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono |
CN1038725C (zh) * | 1993-12-04 | 1998-06-17 | 吉林省鹊源国际生物工程有限公司 | 复方天然香菇营养液 |
US6149891A (en) * | 1995-05-31 | 2000-11-21 | Israel Humanitarian Foundation Ltd. | X-ray contrast medium and method for protecting against harmful effects thereof |
IT1299202B1 (it) * | 1998-05-08 | 2000-02-29 | Dibra Spa | Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo |
US7790141B2 (en) * | 2003-08-11 | 2010-09-07 | Pathak Holdings, Llc | Radio-opaque compounds, compositions containing same and methods of their synthesis and use |
AU2008273037B2 (en) | 2007-07-12 | 2012-11-15 | Ge Healthcare As | Contrast agents |
JP2011500531A (ja) | 2007-10-12 | 2011-01-06 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 造影剤 |
WO2009047319A1 (en) | 2007-10-12 | 2009-04-16 | Ge Healthcare As | Contrast agents |
EP2200655B1 (en) | 2007-10-12 | 2012-07-18 | GE Healthcare AS | Contrast agents |
CN101820924A (zh) | 2007-10-12 | 2010-09-01 | 通用电气医疗集团股份有限公司 | 造影剂 |
EP2203190A1 (en) * | 2007-10-30 | 2010-07-07 | GE Healthcare AS | Contrast agents |
WO2009091758A1 (en) * | 2008-01-14 | 2009-07-23 | Mallinckrodt Inc. | Process for the preparation of iosimenol |
WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
EP3220887A1 (en) | 2014-11-21 | 2017-09-27 | Technical University of Denmark | Gel formulations for local drug release |
CA3023928A1 (en) | 2016-05-20 | 2017-11-23 | Technical University Of Denmark | Palpable marker composition |
WO2020249801A1 (en) | 2019-06-12 | 2020-12-17 | Technical University Of Denmark | Dissacharide formulations for controlled drug release |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2853424A (en) * | 1952-08-06 | 1958-09-23 | Schering Ag | X-ray contrast agents comprising symmetrical bifunctional analogs of nu-acyl derivatives of 2, 4, 6 triiodo-3-amino benzoic acid |
US3178473A (en) * | 1962-03-02 | 1965-04-13 | Nyegaard & Co As | Process for the n-alkylation of acyl anilides halogen substituted in the nucleus |
US3290366A (en) * | 1963-03-06 | 1966-12-06 | Mallinckrodt Chemical Works | 5-amino-nu-alkyl-2, 4, 6-triiodoisophthalamic acid derivatives |
GB1033777A (en) * | 1963-06-06 | 1966-06-22 | Sterling Drug Inc | Bis-anilide derivatives |
US3732293A (en) * | 1968-03-15 | 1973-05-08 | Sterling Drug Inc | Iodinated bis(aminobenzoic acids) and esters thereof |
CH502104A (de) * | 1968-05-02 | 1971-01-31 | Bracco Ind Chimica Spa | Neue Röntgenkontrastmittel und Verfahren zu ihrer Herstellung |
IE34927B1 (en) * | 1969-06-27 | 1975-10-01 | Nyegaard & Co As | Non-ionic iodinated x-ray contrast agents |
US3660464A (en) * | 1970-06-19 | 1972-05-02 | Squibb & Sons Inc | Tri-iodinated diaminobenzoic acid derivatives |
BE787669A (fr) * | 1971-08-17 | 1973-02-19 | Schering Ag | Anilides d'acide n-methyl-dicarboxylique triiodes, et leur procede de preparation |
DD104193A5 (xx) * | 1972-12-22 | 1974-03-05 | ||
DE2629228C2 (de) * | 1976-06-25 | 1984-10-18 | Schering AG, 1000 Berlin und 4709 Bergkamen | Jodierte Isophthalamsäure-Derivate Verfahren zu deren Herstellung sowie deren Verwendung |
CH626873A5 (xx) * | 1977-03-28 | 1981-12-15 | Bracco Ind Chimica Spa |
-
1976
- 1976-06-23 DE DE2628517A patent/DE2628517C2/de not_active Expired
-
1977
- 1977-05-18 NL NLAANVRAGE7705509,A patent/NL189510C/xx not_active IP Right Cessation
- 1977-06-16 FI FI771900A patent/FI67540C/fi not_active IP Right Cessation
- 1977-06-16 DK DK266177A patent/DK150505C/da not_active IP Right Cessation
- 1977-06-20 PL PL1977199019A patent/PL108102B1/pl not_active IP Right Cessation
- 1977-06-20 GB GB25644/77A patent/GB1588733A/en not_active Expired
- 1977-06-20 IE IE1249/77A patent/IE45225B1/en not_active IP Right Cessation
- 1977-06-20 CS CS774059A patent/CS199680B2/cs unknown
- 1977-06-20 GB GB7222/80A patent/GB1588734A/en not_active Expired
- 1977-06-21 LU LU77588A patent/LU77588A1/xx unknown
- 1977-06-21 DD DD7700199616A patent/DD131014A5/xx unknown
- 1977-06-21 GR GR53760A patent/GR71696B/el unknown
- 1977-06-21 IL IL52356A patent/IL52356A/xx unknown
- 1977-06-21 PT PT66690A patent/PT66690B/pt unknown
- 1977-06-21 CH CH761277A patent/CH629751A5/de not_active IP Right Cessation
- 1977-06-22 SE SE7707230A patent/SE436871B/xx not_active IP Right Cessation
- 1977-06-22 AU AU26325/77A patent/AU512304B2/en not_active Expired
- 1977-06-22 SU SU772498151A patent/SU917696A3/ru active
- 1977-06-22 NO NO772202A patent/NO147447C/no unknown
- 1977-06-22 CA CA281,184A patent/CA1106400A/en not_active Expired
- 1977-06-22 ES ES460007A patent/ES460007A1/es not_active Expired
- 1977-06-22 HU HU77SCHE611A patent/HU174228B/hu unknown
- 1977-06-23 FR FR7719234A patent/FR2355808A1/fr active Granted
- 1977-06-23 AT AT443777A patent/AT361117B/de not_active IP Right Cessation
- 1977-06-23 IT IT7724994A patent/IT1237314B/it active
- 1977-06-23 JP JP7489777A patent/JPS537637A/ja active Granted
- 1977-06-23 BE BE178719A patent/BE856039A/xx not_active IP Right Cessation
- 1977-06-23 ZA ZA00773782A patent/ZA773782B/xx unknown
-
1979
- 1979-01-12 US US06/002,901 patent/US4239747A/en not_active Expired - Lifetime
-
1980
- 1980-03-21 CA CA348,166A patent/CA1106401A/en not_active Expired
- 1980-06-18 IL IL60344A patent/IL60344A0/xx unknown
-
1981
- 1981-10-08 IE IE2351/81A patent/IE45226B1/en not_active IP Right Cessation
-
1982
- 1982-08-04 NO NO822674A patent/NO148811C/no unknown
-
1984
- 1984-12-12 DK DK595284A patent/DK165973C/da not_active IP Right Cessation
-
1985
- 1985-07-09 JP JP60149408A patent/JPS61126059A/ja active Granted
-
1993
- 1993-06-09 LU LU88292C patent/LU88292I2/de unknown
Also Published As
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