IL61512A0 - Hologen containing 11ss-hydroxy-3-oxoandrosta-1,4-diene-17ss-carboxylic acids and their preparation - Google Patents
Hologen containing 11ss-hydroxy-3-oxoandrosta-1,4-diene-17ss-carboxylic acids and their preparationInfo
- Publication number
- IL61512A0 IL61512A0 IL61512A IL6151280A IL61512A0 IL 61512 A0 IL61512 A0 IL 61512A0 IL 61512 A IL61512 A IL 61512A IL 6151280 A IL6151280 A IL 6151280A IL 61512 A0 IL61512 A0 IL 61512A0
- Authority
- IL
- Israel
- Prior art keywords
- hologen
- oxoandrosta
- diene
- hydroxy
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH225376A CH628355A5 (en) | 1976-02-24 | 1976-02-24 | METHOD FOR PRODUCING NEW ANDROSTADIEN-17BETA-CARBONIC ACIDS AND THEIR ESTERS AND SALTS. |
Publications (1)
Publication Number | Publication Date |
---|---|
IL61512A0 true IL61512A0 (en) | 1980-12-31 |
Family
ID=4229445
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL51519A IL51519A (en) | 1976-02-24 | 1977-02-22 | Halogen containing 11 beta-hydroxy-3-oxo-androsta-1,4-diene-17 beta-carboxylic acid esters,their manufacture and pharmaceutical compositions containing them |
IL61512A IL61512A0 (en) | 1976-02-24 | 1980-11-19 | Hologen containing 11ss-hydroxy-3-oxoandrosta-1,4-diene-17ss-carboxylic acids and their preparation |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL51519A IL51519A (en) | 1976-02-24 | 1977-02-22 | Halogen containing 11 beta-hydroxy-3-oxo-androsta-1,4-diene-17 beta-carboxylic acid esters,their manufacture and pharmaceutical compositions containing them |
Country Status (26)
Country | Link |
---|---|
US (1) | US4285937A (en) |
JP (1) | JPS52102264A (en) |
AT (1) | AT361141B (en) |
AU (1) | AU513559B2 (en) |
BE (1) | BE851725A (en) |
CA (1) | CA1084483A (en) |
CH (4) | CH628355A5 (en) |
CY (1) | CY1198A (en) |
DD (1) | DD145918A5 (en) |
DE (1) | DE2707336A1 (en) |
DK (1) | DK153493C (en) |
ES (5) | ES456134A1 (en) |
FR (2) | FR2342302A1 (en) |
GB (1) | GB1578243A (en) |
HK (1) | HK57483A (en) |
HU (1) | HU176762B (en) |
IE (1) | IE45023B1 (en) |
IL (2) | IL51519A (en) |
KE (1) | KE3300A (en) |
MX (1) | MX9203366A (en) |
MY (1) | MY8500017A (en) |
NL (1) | NL7701886A (en) |
NZ (1) | NZ183418A (en) |
SE (1) | SE436572B (en) |
SG (1) | SG37383G (en) |
ZA (1) | ZA771087B (en) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4198403A (en) * | 1978-04-05 | 1980-04-15 | Syntex (U.S.A.) Inc. | 17 Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes |
PT69411A (en) * | 1978-04-05 | 1979-04-01 | Syntex Inc | 4-halo etianic acids and derivatives thereof |
US4188385A (en) * | 1978-04-05 | 1980-02-12 | Syntex (U.S.A.) Inc. | Thioetianic acid derivatives |
DE3024008C2 (en) * | 1980-06-24 | 1982-04-15 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Process for the preparation of 17α-hydroxy-ethiocarboxylic acids |
US4607028A (en) * | 1983-08-18 | 1986-08-19 | Ciba-Geigy Corporation | Novel carboxylic acid esters |
SE8306370D0 (en) * | 1983-11-18 | 1983-11-18 | Draco Ab | NOVEL ANDROSTANE-17BETA-CARBOXYLIC ACID ESTERS, A PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, COMPOSITIONS AND METHOD FOR THE TREATMENT OF INFLAMMATORY CONDITIONS |
SE8501693D0 (en) * | 1985-04-04 | 1985-04-04 | Draco Ab | NOVEL 16,17-ACETALSUBSTITUTED ANDROSTANE-17BETA-CARBOXYLIC ACID ESTERS |
IL78144A0 (en) * | 1985-04-04 | 1986-07-31 | Draco Ab | Novel androstane-17beta-carboxylic acid esters |
JPH04506066A (en) * | 1989-06-16 | 1992-10-22 | ジ・アップジョン・カンパニー | Suramin-type compounds and anti-angiogenic steroids to inhibit angiogenesis |
US6596260B1 (en) * | 1993-08-27 | 2003-07-22 | Novartis Corporation | Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol |
US5646136A (en) * | 1994-01-04 | 1997-07-08 | Duke University | Methods of inhibiting angiogenesis and tumor growth, and treating ophthalmologic conditions with angiostatic and therapeutic steroids |
US5981517A (en) * | 1996-05-09 | 1999-11-09 | Soft Drugs, Inc. | Androstene derivatives |
GB0015876D0 (en) * | 2000-06-28 | 2000-08-23 | Novartis Ag | Organic compounds |
AR032361A1 (en) * | 2000-08-05 | 2003-11-05 | Glaxo Group Ltd | DERIVATIVES OF ANDROSTAN AND SALTS AND SOLVATOS OF THE SAME, ITS USE FOR THE MANUFACTURE OF MEDICINES, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE SUCH COMPOUNDS, PROCESS FOR THE PREPARATION OF SUCH COMPOUNDS, AND USEFUL INTERMEDIARIES IN THE PREPARATION OF SUCH COMPOUNDS |
US6858596B2 (en) * | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivative |
US6750210B2 (en) * | 2000-08-05 | 2004-06-15 | Smithkline Beecham Corporation | Formulation containing novel anti-inflammatory androstane derivative |
US6777399B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
GB0019172D0 (en) * | 2000-08-05 | 2000-09-27 | Glaxo Group Ltd | Novel compounds |
US6777400B2 (en) * | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
US6759398B2 (en) * | 2000-08-05 | 2004-07-06 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative |
US6858593B2 (en) * | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
US6787532B2 (en) * | 2000-08-05 | 2004-09-07 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivatives |
UA77656C2 (en) * | 2001-04-07 | 2007-01-15 | Glaxo Group Ltd | S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent |
JP4446661B2 (en) * | 2001-04-30 | 2010-04-07 | グラクソ グループ リミテッド | Anti-inflammatory, 17β-carbothioate derivative of androstane having a cyclic ester group at the 17α position |
US20050175545A1 (en) * | 2002-02-04 | 2005-08-11 | Keith Biggadike | Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist |
GB0202635D0 (en) * | 2002-02-05 | 2002-03-20 | Glaxo Wellcome Mfg Pte Ltd | Formulation containing novel anti-inflammatory androstane derivative |
GB2389530B (en) | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
WO2004112800A1 (en) * | 2003-06-19 | 2004-12-29 | Bodor Nicholas S | Enhancement of activity and/or duration of action of selected anti-inflammatory steroids |
ES2339351T3 (en) * | 2003-06-19 | 2010-05-19 | Nicholas S. Bodor | IMPROVEMENT OF THE ACTIVITY AND / OR DURATION OF THE ACTION OF SOFT ANTI-INFLAMMATORY STEROIDS FOR TOPICAL OR OTHER LOCAL APPLICATION. |
GB0507165D0 (en) * | 2005-04-08 | 2005-05-18 | Glaxo Group Ltd | Novel crystalline pharmaceutical product |
US20090054382A1 (en) * | 2005-10-19 | 2009-02-26 | Abhijit Ray | Compositions of phosphodiesterase type iv inhibitors |
US7687484B2 (en) * | 2006-05-25 | 2010-03-30 | Bodor Nicholas S | Transporter enhanced corticosteroid activity |
US7691811B2 (en) * | 2006-05-25 | 2010-04-06 | Bodor Nicholas S | Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye |
GB0615108D0 (en) * | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel formulations |
US8227027B2 (en) * | 2007-12-07 | 2012-07-24 | Presspart Gmbh & Co. Kg | Method for applying a polymer coating to an internal surface of a container |
EP2111861A1 (en) | 2008-04-21 | 2009-10-28 | Ranbaxy Laboratories Limited | Compositions of phosphodiesterase type IV inhibitors |
US8835410B2 (en) | 2011-05-10 | 2014-09-16 | Bodor Laboratories, Inc. | Treatment of eyelid dermatitis |
CN111100176A (en) * | 2019-12-20 | 2020-05-05 | 重庆华邦胜凯制药有限公司 | Preparation method of compound |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3636010A (en) * | 1968-12-23 | 1972-01-18 | Ciba Geigy Corp | Esters of steroid-17-carboxylic acids |
GB1384372A (en) * | 1971-01-20 | 1975-02-19 | Glaxo Lab Ltd | Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids |
GB1438940A (en) * | 1972-07-19 | 1976-06-09 | Glaxo Lab Ltd | 17beta-haloalkoxycarbonyl-17alpha-oxysteroids |
US4093721A (en) * | 1974-08-30 | 1978-06-06 | Glaxo Laboratories Limited | Pharmaceutical compositions of 6α,9α-difluoro-androst-4-ene-17β-carboxylates and derivatives thereof |
GB1514476A (en) * | 1974-08-30 | 1978-06-14 | Glaxo Lab Ltd | Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates |
-
1976
- 1976-02-24 CH CH225376A patent/CH628355A5/en not_active IP Right Cessation
-
1977
- 1977-02-18 CY CY1198A patent/CY1198A/en unknown
- 1977-02-18 GB GB6955/77A patent/GB1578243A/en not_active Expired
- 1977-02-19 DE DE19772707336 patent/DE2707336A1/en active Granted
- 1977-02-22 FR FR7705053A patent/FR2342302A1/en active Granted
- 1977-02-22 CA CA272,291A patent/CA1084483A/en not_active Expired
- 1977-02-22 DD DD77197502A patent/DD145918A5/en unknown
- 1977-02-22 ES ES456134A patent/ES456134A1/en not_active Expired
- 1977-02-22 IL IL51519A patent/IL51519A/en unknown
- 1977-02-22 NL NL7701886A patent/NL7701886A/en unknown
- 1977-02-23 AU AU22572/77A patent/AU513559B2/en not_active Expired
- 1977-02-23 AT AT119477A patent/AT361141B/en not_active IP Right Cessation
- 1977-02-23 DK DK079077A patent/DK153493C/en not_active IP Right Cessation
- 1977-02-23 HU HU77CI1720A patent/HU176762B/en unknown
- 1977-02-23 ZA ZA00771087A patent/ZA771087B/en unknown
- 1977-02-23 SE SE7701999A patent/SE436572B/en not_active IP Right Cessation
- 1977-02-23 IE IE382/77A patent/IE45023B1/en not_active IP Right Cessation
- 1977-02-23 NZ NZ183418A patent/NZ183418A/en unknown
- 1977-02-23 BE BE175169A patent/BE851725A/en not_active IP Right Cessation
- 1977-02-24 JP JP1874377A patent/JPS52102264A/en active Granted
-
1978
- 1978-01-27 FR FR7802324A patent/FR2369297A1/en active Granted
- 1978-03-01 ES ES467432A patent/ES467432A1/en not_active Expired
- 1978-03-01 ES ES467434A patent/ES467434A1/en not_active Expired
- 1978-03-01 ES ES467433A patent/ES467433A1/en not_active Expired
- 1978-03-01 ES ES467430A patent/ES467430A1/en not_active Expired
-
1979
- 1979-10-30 US US06/089,677 patent/US4285937A/en not_active Expired - Lifetime
-
1980
- 1980-11-19 IL IL61512A patent/IL61512A0/en unknown
-
1981
- 1981-06-11 CH CH383281A patent/CH628356A5/en not_active IP Right Cessation
- 1981-06-11 CH CH383181A patent/CH629824A5/en not_active IP Right Cessation
- 1981-06-11 CH CH383381A patent/CH628641A5/en not_active IP Right Cessation
-
1983
- 1983-06-23 KE KE3300A patent/KE3300A/en unknown
- 1983-06-27 SG SG373/83A patent/SG37383G/en unknown
- 1983-11-17 HK HK574/83A patent/HK57483A/en unknown
-
1985
- 1985-12-30 MY MY17/85A patent/MY8500017A/en unknown
-
1992
- 1992-06-25 MX MX9203366A patent/MX9203366A/en unknown
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