CN110894240B - 结合cd3和肿瘤抗原的异二聚体抗体 - Google Patents

结合cd3和肿瘤抗原的异二聚体抗体 Download PDF

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CN110894240B
CN110894240B CN201911081732.7A CN201911081732A CN110894240B CN 110894240 B CN110894240 B CN 110894240B CN 201911081732 A CN201911081732 A CN 201911081732A CN 110894240 B CN110894240 B CN 110894240B
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scfv
antibody
sequence
variants
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CN110894240A (zh
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G·摩尔
J·德加莱斯
M·贝尔尼特
S·楚
R·拉什德
U·穆赫哈
S-H·李
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Xencor Inc
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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CN201911081732.7A 2014-11-26 2015-11-25 结合cd3和肿瘤抗原的异二聚体抗体 Active CN110894240B (zh)

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US201462085027P 2014-11-26 2014-11-26
US201462085106P 2014-11-26 2014-11-26
US201462084908P 2014-11-26 2014-11-26
US201462085117P 2014-11-26 2014-11-26
US62/085,027 2014-11-26
US62/085,106 2014-11-26
US62/085,117 2014-11-26
US62/084,908 2014-11-26
US201562159111P 2015-05-08 2015-05-08
US62/159,111 2015-05-08
US201562251005P 2015-11-04 2015-11-04
US201562250971P 2015-11-04 2015-11-04
US62/250,971 2015-11-04
US62/251,005 2015-11-04
CN201580074226.9A CN107207610B (zh) 2014-11-26 2015-11-25 结合cd3和肿瘤抗原的异二聚体抗体
PCT/US2015/062772 WO2016086189A2 (en) 2014-11-26 2015-11-25 Heterodimeric antibodies that bind cd3 and tumor antigens

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