CN107898791A - 布鲁顿酪氨酸激酶(btk)抑制剂的应用 - Google Patents

布鲁顿酪氨酸激酶(btk)抑制剂的应用 Download PDF

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Publication number
CN107898791A
CN107898791A CN201711036665.8A CN201711036665A CN107898791A CN 107898791 A CN107898791 A CN 107898791A CN 201711036665 A CN201711036665 A CN 201711036665A CN 107898791 A CN107898791 A CN 107898791A
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Prior art keywords
cells
substituted
unsubstituted
alkyl
inhibitor
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CN201711036665.8A
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Chinese (zh)
Inventor
J·J·巴吉
劳伦斯·埃利亚斯
格温·伊夫
埃里克·赫德里克
D·J·劳里
T·D·莫迪
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Pharmacyclics LLC
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Pharmacyclics LLC
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Application filed by Pharmacyclics LLC filed Critical Pharmacyclics LLC
Publication of CN107898791A publication Critical patent/CN107898791A/zh
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CN110724143B (zh) * 2019-10-09 2021-03-23 清华大学 一种靶向btk蛋白降解化合物的制备及其在治疗自身免疫系统疾病与肿瘤中的应用

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