CN107847396B - 用于安全的伸缩的卡扣配合在注射剂小瓶上的液体药物转移装置 - Google Patents

用于安全的伸缩的卡扣配合在注射剂小瓶上的液体药物转移装置 Download PDF

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CN107847396B
CN107847396B CN201680040655.9A CN201680040655A CN107847396B CN 107847396 B CN107847396 B CN 107847396B CN 201680040655 A CN201680040655 A CN 201680040655A CN 107847396 B CN107847396 B CN 107847396B
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乌瑞·大卫
伊格·德仁伯格
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West Pharma Services IL Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485—Ampoule holder connected to rest of syringe
    • A61M2005/2492—Ampoule holder connected to rest of syringe via snap connection

Abstract

液体药物转移装置包括小瓶转接器，该小瓶转接器具有至少两个非邻近的小瓶保持弯曲部件和至少两个非邻近的小瓶导向弯曲部件。该小瓶导向弯曲部件各自被设置有距离小瓶转接器顶壁一定距离的目标设计枢纽区用来在伸缩的卡扣配合在注射剂小瓶上时有目的地在枢纽区转动。小瓶保持弯曲部件可兼作小瓶导向弯曲部件，条件是它们的枢纽区相对于小瓶转接器顶壁在它们的向内突出的小瓶保持肋状物的远侧。

Description

用于安全的伸缩的卡扣配合在注射剂小瓶上的液体药物转移 装置
技术领域
本发明涉及用于安全的伸缩的卡扣配合在注射剂小瓶上的液体药物转移装置。
背景技术
ISO 8362-1注射剂容器和配件-部分1:由玻璃管组成的注射剂小瓶使小瓶尺寸、小瓶规格和小瓶公差标准化注射剂小瓶。ISO 8362-1定义了下述术语：小瓶管、小瓶冠以及小瓶管和小瓶冠中间的小瓶颈。小瓶管具有闭端和外直径(OD)d1。小瓶冠具有冠开口和外直径(OD)d2。小瓶颈具有外直径(OD)d3和内直径(ID)d4。小瓶冠具有围绕冠开口的最高小瓶冠边缘和朝向小瓶颈的最低小瓶冠边缘。冠开口具有与小瓶颈相同的内直径。注射剂小瓶具有小瓶颈和小瓶管之间的小瓶肩。小瓶管和小瓶肩在最高小瓶管边缘处接合。该直径具有以下关系：d1>d2>d3>d4。大多数小瓶冠外直径可用于多个小瓶管外直径，例如小瓶冠外直径d2＝20mm可用于3个标准的小瓶管外直径d1＝22或24或30mm。因此，注射剂小瓶通过它们的小瓶冠外直径(而不是它们的小瓶管外直径)被提到。
液体药物转移装置包括小瓶转接器，该小瓶转接器具有横向的小瓶转接器顶壁、用于刺穿小瓶瓶塞的中空的穿刺插管和向下悬挂的裙。该向下悬挂的裙足够向下延伸用来遮蔽穿刺插管端以防止疏忽的用户与该穿刺插管端接触。该向下悬挂的裙经设计形状和规格以紧贴地伸缩地卡扣配合到特定的小瓶冠外直径上。因此，小瓶转接器以类似于注射剂小瓶的方式按小瓶冠外直径被提及，就小瓶冠外直径而言，小瓶转接器准备在其上伸缩的卡扣配合。为了确保小瓶转接器能够伸缩地卡扣配合到特定的小瓶冠外直径的全部的标准的小瓶管外直径上，它的向下悬挂的裙规格被设计以在小瓶肩上终止。然而，此类向下悬挂的裙并没有帮助用户对齐小瓶转接器与注射剂小瓶同轴，这导致常见的不对准。小瓶转接器相对于注射剂小瓶的不对准通常导致小瓶瓶塞中撕破的形成，尤其在共同拥有的美国专利号8,608,723(Lev et al.，发明名称：具有密封装置的流体转移装置)中讨论的。
共同拥有的美国专利号8,070,739(Zinger et al.，发明名称：用于自动防故障的正确的卡扣配合到药瓶上的液体药物转移装置)公开了经设计以帮助用户对齐小瓶转接器和注射剂小瓶的具有小瓶转接器的液体药物转移装置。该液体药物转移装置包括具有向下悬挂的裙的小瓶转接器，该向下悬挂的裙具有至少两个非邻近的小瓶保持弯曲部件用于卡扣配合在小瓶冠上方用于小瓶保持的目的和至少两个比它们的对应的小瓶保持弯曲部件长的非邻近的小瓶导向弯曲部件用来在注射剂小瓶上卡扣配合小瓶转接器之前相对于注射剂小瓶导向小瓶转接器。
在卡扣配合在注射剂小瓶上期间，该小瓶导向弯曲部件相对于它们的小瓶转接器中心线在它们与它们的小瓶转接器顶壁的连接处向外径向弯曲时通常邻接小瓶肩并且向外径向滑动。该小瓶导向弯曲部件的向外径向滑动取决于具有方便向外径向滑动的陡坡的小瓶肩的斜度。小瓶导向弯曲部件的在它们的与小瓶转接器顶壁的连接处的向外径向弯曲导致与用于将小瓶转接器伸缩地卡扣配合在注射剂小瓶上的手动连接力(manualattachment force)相反的拆除反作用力(detachment reaction force)。注射剂管的直径越大，拆除反作用力越大，其最多导致减弱伸缩的卡扣配合以及在最坏的情况下导致拆除。
再者，小瓶转接器在注射剂小瓶上的伸缩的卡扣配合对于特定的小瓶冠外直径的所有的小瓶管外直径不是一致的，因为针对不同的小瓶管外直径，小瓶导向弯曲部件是径向地向外地不同的弯曲。另外，较大的小瓶管外直径引起小瓶转接器伸缩的卡扣配合在注射剂小瓶上以呈现不适合用户抓住小瓶转接器(例如用于连接和拆除注射器)的抓取面。
因此，有必要提供具有小瓶转接器的液体药物转移装置，该小瓶转接器用于提供安全的伸缩的卡扣配合在特定的小瓶冠外直径的所有的标准的小瓶管外直径的小瓶冠上。
发明内容
本发明针对的是液体药物转移装置，该液体药物转移装置包括经设计用于安全的伸缩的卡扣配合在注射剂小瓶上的小瓶转接器。该液体药物转移装置具有与迄今为止描述的美国专利号8,070,739的液体药物转移装置类似的构造，但是它们的小瓶导向弯曲部件还设置有目标设计的枢纽区(purpose design hinged zone)，该目标设计的枢纽区距离小瓶转接器顶壁一定的距离，用于在伸缩的卡扣配合在注射剂小瓶上时有目的的在该枢纽区转动，这与在小瓶转接器顶壁处的弯曲相反。枢纽区阻止小瓶转接器形成了明显的与手动连接力相反的拆除反作用力，这可出现在迄今为止描述的美国专利号8,070,739的液体药物转移装置中。因此，本发明的液体药物转移装置可容易与特定的小瓶冠外直径的所有的小瓶管外直径的注射剂小瓶一起使用。本发明的液体药物转移装置可设置有比它的小瓶保持弯曲部件长的穿刺套管和比它的穿刺套管长的小瓶导向弯曲部件，用于在不有损安全的伸缩的卡扣配合在注射剂小瓶上的情况下遮挡该穿刺套管。
该小瓶导向弯曲部件优选地具有它们的枢纽区，该枢纽区设置在它们的对应的小瓶保持弯曲部件的至少部分地圆周地向内延伸的突出的小瓶保持肋状物的对面，使得将小瓶转接器伸缩地卡扣配合在注射剂小瓶上，而没有卡扣配合在注射剂小瓶上时，小瓶导向弯曲部件也紧贴地围绕小瓶冠。在它们的枢纽区有必要相对于小瓶转接器顶壁设置在它们的至少部分地圆周地向内延伸的突出的小瓶保持肋状物的远侧的条件下，小瓶保持弯曲部件还可通过以类似小瓶导向弯曲部件的方式与枢纽区一起形成兼作小瓶导向弯曲部件。因此，本发明的液体药物转移装置可仅仅被设置有小瓶保持弯曲部件，该小瓶保持弯曲部件具有至少两个兼作具有枢纽区的小瓶导向弯曲部件的小瓶保持弯曲部件。
附图的简要说明
为了理解本发明并且明白它在实践中如何被实施，仅仅借助非限制性实例，现在优选的实例被描述了，参见附图，其中相同的部分被做了同样编号，以及其中：
图1显示了ISO 8362-1部分4规格图，定义了小瓶管外直径d1、小瓶冠外直径d2、小瓶颈外直径d3和小瓶颈内直径d4；
图2是根据美国专利号8,070,739的传统的20mm母小瓶转接器(female vialadapter)的透视图；
图3是沿着图2中的线A-A图2的20mm母小瓶转接器的纵向截面图；
图4是沿着图2中的线A-A的纵向截面图，显示了图2的20mm母小瓶转接器伸缩的卡扣配合在具有小瓶管外直径d1＝22mm的20mm注射剂小瓶上；
图5是沿着图2中的线A-A的纵向截面图，显示了图2的20mm母小瓶转接器伸缩的卡扣配合在具有小瓶管外直径d1＝30mm的20mm注射剂小瓶上；
图6是根据本发明的第一实施方案的20mm母小瓶转接器的透视图；
图7是沿着图6中的线B-B的图6的20mm母小瓶转接器的纵向截面图；
图8是纵向截面图，显示了在伸缩的卡扣配合在具有小瓶管外直径d1＝22mm的20mm注射剂小瓶上之前图6的20mm母小瓶转接器；
图9是纵向截面图，显示了图6的20mm母小瓶转接器伸缩的卡扣配合在图8的注射剂小瓶上；
图10是纵向截面图，显示了在伸缩的卡扣配合在具有小瓶管外直径d1＝30mm的20mm注射剂小瓶上之前图6的20mm母小瓶转接器；
图11是纵向截面图，显示了图6的20mm母小瓶转接器伸缩的卡扣配合在图10的注射剂小瓶上；
图12是根据本发明的第二实施方案的20mm母小瓶转接器的透视图；
图13是沿着图12中的线C-C图12的20mm母小瓶转接器的纵向截面图；
图14是根据本发明的第三实施方案的20mm母小瓶转接器的透视图；
图15是沿着图14中的线D-D图14的20mm母小瓶转接器的纵向截面图；
图16是根据本发明的第四实施方案的20mm母小瓶转接器的透视图；
图17是图16的母小瓶转接器的俯视图；
图18是沿着图16中的线E-E图16的20mm母小瓶转接器的纵向截面图；
图19是根据本发明的第五实施方案的通气式20mm母小瓶转接器的透视图；以及
图20是根据本发明的第六实施方案的液体转移装置的透视图。
本发明优选实施方案的详细描述
图1显示了注射剂小瓶10，注射剂小瓶10具有纵向的注射剂小瓶中心线11并且包括一端封闭的小瓶管12、具有冠开口14的管状的小瓶冠13和在小瓶管12和小瓶冠13之间的小瓶颈16。小瓶冠13具有围绕冠开口14的最高小瓶冠边缘17和朝向小瓶颈16的最低小瓶冠边缘18。注射管10包括在小瓶管12和小瓶颈16之间的小瓶肩19。小瓶管12和小瓶肩19在最高小瓶管边缘21处汇合。小瓶管12具有外直径d1。小瓶冠13具有外直径d2。小瓶颈16具有外直径d3和内直径d4。冠开口14具有与小瓶颈16相同的内直径。这些直径具有以下关系：d1>d2>d3>d4。在小瓶冠外直径d2＝20mm的条件下，注射管外直径d1可以是以下3个标准直径中的一个：d1＝22或24或30mm。图4和图5显示了注射剂小瓶10还包括用于塞住冠开口14的小瓶瓶塞22和密封瓶塞22的铝带23。
图2和图3显示了根据迄今提到的美国专利号8,070,739的传统的液体药物转移装置30，药物转移装置30由用于伸缩的卡扣配合在20mm注射剂小瓶上的母小瓶转接器构成。该母小瓶转接器30具有纵向的小瓶转接器中心线31并且包括横向于纵向的小瓶转接器中心线31的小瓶转接器顶壁32和从小瓶转接器顶壁32向下悬挂的大体上圆柱形裙33用于伸缩地滑动地在其中接收小瓶冠。小瓶转接器顶壁32包括用于刺穿小瓶瓶塞的向下悬挂的中空的穿刺插管34。小瓶转接器顶壁32包括流体转移端口36，流体转移端口36是由与穿刺插管34相对的直立的母鲁尔接头构成并且与穿刺插管34流体连通。穿刺插管34包括具有至少一个用于通到小瓶管的流动孔38的穿刺插管端37。
裙33包括由围绕纵向的小瓶转接器中心线31平均间隔的交替的小瓶保持弯曲部件41和小瓶导向弯曲部件42构成的6个弯曲部件39。在母小瓶转接器30的俯视图中，3个小瓶保持弯曲部件41和3个小瓶导向弯曲部件42围绕纵向的小瓶转接器中心线31占据相同的外围长度。小瓶保持弯曲部件41具有距离小瓶转接器顶壁32长度L1的小瓶保持弯曲部件端(vial retention flex member tips)43。小瓶导向弯曲部件42具有距离小瓶转接器顶壁32的长度L2的小瓶导向弯曲部件端(vial guidance flex member tips)44，其中L2>L1。小瓶保持弯曲部件41具有部分地外围地向内延伸的突出的小瓶保持肋状物(vial retentionribs)46用于卡扣配合在小瓶冠上方用于小瓶保持目的。
图4和5显示了相应地伸缩的卡扣配合在具有22mm小瓶管外直径和30mm小瓶管外直径的20mm注射剂小瓶上的20mm母小瓶转接器30。图4显示了小瓶导向弯曲部件42相对于小瓶转接器中心线31在小瓶转接器顶壁32处稍稍地向外径向地弯曲，类似于美国专利号8,070,739中的图3E所示的。相比图4，图5显示了小瓶导向弯曲部件42相对于小瓶转接器中心线31在小瓶转接器顶壁32处更加径向地向外弯曲。母小瓶转接器30呈现了与手动连接力(A所示)相反的拆除反作用力(D所示)。相比图4的20mm小瓶管外直径，在图5的30mm小瓶管外直径的情况下，用户感受到更大的拆除反作用力D。
图4和图5显示了小瓶保持弯曲部件41和小瓶导向弯曲部件42没有以一致的方式紧贴地包围小瓶冠13。在图4中，因为小瓶管外直径仅仅稍微地大于小瓶冠外直径，在连接和拆除注射器期间，通过用户抓住母小瓶转接器30，两种类型的弯曲部件41和42之间的差别可以想象是不明显的。在图5中，在连接和拆除注射器期间，通过用户抓住母小瓶转接器30，此类向外径向弯曲是很明显的，从而呈现了不适合用户抓住母小瓶转接器30的抓取面。
图6和图7显示了液体药物转移装置50A，液体药物转移装置50A是由用于伸缩的卡扣配合安装在20mm注射剂小瓶10上的母小瓶转接器构成。母小瓶转接器50A具有与母小瓶转接器30类似的构造和用途，因此，相同的部分被同样编号了。母小瓶转接器50A与母小瓶转接器30不同之处在于后者50A具有比小瓶保持弯曲部件41长的穿刺插管34。另外，后者50A包括小瓶导向弯曲部件51，各自具有枢纽区(hinged zone)52,枢纽区52将每个小瓶导向弯曲部件51划分为邻近小瓶转接器顶壁32的较高小瓶导向弯曲部件部分53和远离小瓶转接器顶壁32的较低小瓶导向弯曲部件部分54。小瓶导向弯曲部件51以距离小瓶转接器顶壁32的长度L3终止在小瓶导向弯曲部件端56，其中L3>L2>L1。
小瓶保持弯曲部件41具有从小瓶转接器顶壁32偏离的部分地圆周地向内延伸的突出的小瓶保持肋状物46。枢纽区52大体上被设置在部分地圆周地向内延伸的突出的小瓶保持肋状物46的对面。因此，在伸缩的卡扣配合母小瓶转接器50A在20mm注射剂小瓶上时，枢纽区52被配置在最低小瓶冠边缘18和最高小瓶管边缘21之间。枢纽区52可被实现，例如通过减小材料厚度，例如通过外部的外围的凹槽57。或者，枢纽区52可通过由两个或以上空间上分隔的枢纽58连接在一起的较高小瓶导向弯曲部件53和较低小瓶导向弯曲部件54实现，如图12和图13中所示的。
图8和图9显示了在伸缩的卡扣配合在注射剂小瓶10(注射剂小瓶10具有20mm小瓶冠外直径和22mm小瓶管外直径)上之前和之后的母小瓶转接器50A。图8显示了随着母小瓶转接器50A接近注射剂小瓶10，小瓶导向弯曲部件51帮助母小瓶转接器50A相对于注射剂小瓶10置于中心位置。在朝向注射剂小瓶10继续按压母小瓶转接器50A时，小瓶导向弯曲部件51最初地滑下铝带23直至它们接触小瓶肩19。小瓶保持弯曲部件41以类似于母小瓶转接器30的方式在它们与小瓶转接器顶壁32的连接处弯曲以卡扣配合在小瓶冠13上。图9显示了由于小瓶导向弯曲部件端56接触小瓶肩19并且朝向最高小瓶管边缘21向外径向滑动而不是在它们与小瓶转接器顶壁32的连接处弯曲，小瓶导向弯曲部件51相对于纵向的小瓶转接器中心线31在它们各自的枢纽区52径向地向外转动。随着他施加连接力A，用户可以感受到轻微的拆除反作用力D。图9显示了较高小瓶导向弯曲部件部分53保持垂直(类似小瓶保持弯曲部件41，与小瓶导向弯曲部件42不同)使得较高小瓶导向弯曲部件部分53和小瓶保持弯曲部件41紧贴地环绕小瓶冠13。
图10和图11对应于图8和图9并且不同之处在于他们显示了在伸缩的卡扣配合在注射剂小瓶10上之前和之后的母小瓶转接器50A，注射剂小瓶10具有相同的20mm小瓶冠外直径但具有30mm的小瓶管外直径。图11显示了由于小瓶导向弯曲部件端56接触小瓶肩19并且朝向最高小瓶管边缘21径向向外滑动，小瓶导向弯曲部件51相对于纵向的小瓶转接器中心线31在它们各自的枢纽区52径向地向外转动。随着他施加连接力A(比图5的拆除反作用力D小很多)，用户可以感受到轻微的拆除反作用力D。图11显示了较高小瓶导向弯曲部件部分53保持垂直(类似小瓶保持弯曲部件41，与小瓶导向弯曲部件42不同)使得较高小瓶导向弯曲部件部分53和小瓶保持弯曲部件41紧贴地环绕小瓶冠13。因此，母小瓶转接器50A同样地被用于伸缩的卡扣配合在所有的它的相关的标准的小瓶管外直径22mm、24mm和30mm的20mm注射剂小瓶上。
图14和图15显示了也由母小瓶转接器构成的液体药物转移装置50B，该母小瓶转接器在构造和用途方面类似母小瓶转接器50A，因此，相同的部分被作了同样的编号。后者50B不同于前者50A之处在于后者50B包括6个小瓶保持弯曲部件61并且没有小瓶导向弯曲部件。该6个小瓶保持弯曲部件61各自包括类似枢纽区52的枢纽区62，从而将每个小瓶保持弯曲部件61分成邻近小瓶转接器顶壁32的较高小瓶保持弯曲部件部分63和远离小瓶转接器顶壁32的较低小瓶保持弯曲部件部分64。枢纽区62有必要相对于小瓶转接器顶壁32被设置在向内突出的小瓶保持肋状物46的远侧。小瓶保持弯曲部件61以距离小瓶转接器顶壁32的长度L4终止在小瓶保持弯曲部件端66，其中L4＝L3。枢纽区62是由外部的外围的凹槽67构成。
图16到图18显示了液体药物装置50C也由在构造和用途方面类似母小瓶转接器50B的母小瓶转接器构成，因此，相同的部分被作了同样的编号。母小瓶转接器50C不同于母小瓶转接器50B之处在于它包括两个正好相反的小瓶保持弯曲部件61和两个正好相反的小瓶导向弯曲部件71。两个正好相反的小瓶导向弯曲部件71经设计防止在小瓶转接器顶壁32的任何弯曲(其仍然可能在小瓶导向弯曲部件51的情况中发生)。此类防止是通过小瓶导向弯曲部件71围绕纵向的小瓶转接器中心线31对向图17的俯视图中至少90°的扇形角实现的。通常，两个小瓶保持弯曲部件61各自对向扇形角α＝60°以及两个小瓶导向弯曲部件71各自对向扇形角β＝120°。
小瓶导向弯曲部件71各自包括枢纽区72，枢纽区72将各个小瓶导向弯曲部件71分为邻近小瓶转接器顶壁32的较高小瓶导向弯曲部件部分73和远离小瓶转接器顶壁32的一对空间上分隔的较低小瓶导向弯曲部件部分74。小瓶导向弯曲部件71终止在小瓶导向弯曲部件端76。在伸缩的卡扣配合母小瓶转接器50C在注射剂小瓶10上时，由于小瓶导向弯曲部件端76接触小瓶肩19并且朝向最高小瓶管边缘21向外径向滑动，较低小瓶导向弯曲部件部分74相对于纵向的小瓶转接器中心线31在它们的各自的枢纽区72径向地向外转动。
图19显示了根据本发明的教导，由开衩的母小瓶转接器(vented female vialadapter)构成的液体药物转移装置50D。
图20显示了根据本发明的教导，液体药物装置50E由共同拥有的美国专利号6,238,372(Zinger等)公开的流体控制装置构成并且包括小瓶转接器。
虽然本发明的具体实施方案被说明了并且被描述了，各种其它的变化和修改可以被做出而不脱离本发明的精神和范围，对本领域技术人员来说，是显而易见的。

Claims (6)

1.液体药物转移装置，所述液体药物转移装置用于安全的伸缩的卡扣配合在注射剂小瓶上，所述注射剂小瓶具有纵向的注射剂小瓶中心线并且包括一端封闭的小瓶管、具有由小瓶瓶塞塞住的冠开口的管状的小瓶冠、在小瓶管和小瓶冠中间的小瓶颈、在小瓶管和小瓶颈中间的小瓶肩，所述小瓶冠具有朝向所述冠开口的最高小瓶冠边缘和朝向所述小瓶颈的最低小瓶冠边缘，所述小瓶管和所述小瓶肩在最高小瓶管边缘处汇合，
所述小瓶管具有小瓶管外直径d1，所述小瓶冠具有小瓶冠外直径d2，所述小瓶颈具有小瓶颈外直径d3和小瓶颈内直径d4其中d1>d2>d3>d4，以及所述小瓶管外直径d1选自预定范围的至少一个用于小瓶冠外直径d2的小瓶管外直径d1，所述液体药物转移装置包括：
(a)小瓶转接器，所述小瓶转接器具有纵向的小瓶转接器中心线并且包括横向于所述纵向的小瓶转接器中心线的小瓶转接器顶壁，从所述小瓶转接器顶壁向下悬挂的用于伸缩地滑动地在其中接收所述小瓶冠的大体上圆柱形的裙和用于刺穿小瓶瓶塞的中空的穿刺插管，所述穿刺插管具有穿刺插管端，所述穿刺插管端具有至少一个用于通到小瓶管的流体孔，
所述裙包括：
i)至少两个非邻近的小瓶保持弯曲部件，所述至少两个非邻近的小瓶保持弯曲部件具有在所述小瓶转接器顶壁的远侧的小瓶保持弯曲部件端，每个所述小瓶保持弯曲部件具有至少部分地圆周地向内延伸的突出的小瓶保持肋状物用于卡扣配合在小瓶冠上方用于小瓶保持目的，
ii)至少两个非邻近的小瓶导向弯曲部件，所述至少两个非邻近的小瓶导向弯曲部件至少与所述至少两个非邻近的小瓶保持弯曲部件一样长并且具有在所述小瓶转接器顶壁的远侧的小瓶导向弯曲部件端，所述至少两个非邻近的小瓶导向弯曲部件各自具有距离所述小瓶转接器顶壁一定距离的沿所述小瓶导向弯曲部件设置的枢纽区，从而将每个所述小瓶导向弯曲部件分成邻近所述小瓶转接器顶壁的较高小瓶导向弯曲部件部分和在所述小瓶转接器顶壁的远侧的较低小瓶导向弯曲部件部分，
在当伸缩的卡扣配合所述小瓶转接器在注射剂小瓶上时所述小瓶导向弯曲部件端接触所述小瓶肩时，所述至少两个非邻近的小瓶导向弯曲部件相对于纵向的小瓶转接器中心线在它的各自的枢纽区径向地向外转动；以及
(b)与所述穿刺插管流体连通的至少一个流体转移端口。
2.根据权利要求1所述的装置，其特征在于，所述至少两个非邻近的小瓶保持弯曲部件与所述枢纽区一起形成兼作所述至少两个非邻近的小瓶导向弯曲部件，以及每个所述枢纽区沿所述小瓶导向弯曲部件相比它的至少部分地圆周地向内延伸的突出的小瓶保持肋状物进一步远离所述小瓶转接器顶壁，使得每个所述小瓶保持弯曲部件在当伸缩的卡扣配合所述小瓶转接器在注射剂小瓶上时所述小瓶保持弯曲部件端接触小瓶肩时相对于纵向的小瓶转接器中心线在它的各自的枢纽区径向地向外转动。
3.根据权利要求1所述的装置，其特征在于，所述至少两个非邻近的小瓶导向弯曲部件每个具有所述枢纽区，所述枢纽区沿着所述小瓶导向弯曲部件与所述至少部分地圆周地向内延伸的突出的小瓶保持肋状物以同样的距离远离所述小瓶转接器顶壁使得在伸缩的卡扣配合所述小瓶转接器在注射剂小瓶上时，对来自预定范围的至少一个小瓶管外直径d1的每个小瓶管外直径d1来说，所述至少两个较高小瓶导向弯曲部件部分和所述至少两个小瓶保持弯曲部件以一致的方式紧贴地环绕小瓶冠。
4.根据权利要求3所述的装置，其特征在于，每个所述小瓶导向弯曲部件围绕所述纵向的小瓶转接器中心线对向至少90°的扇形角并且包括一对空间上分隔的较低小瓶导向弯曲部件部分。
5.根据权利要求1到4任一项所述的装置，其特征在于，所述枢纽区是由外部的外围的凹槽构成。
6.根据权利要求1到4任一项所述的装置，其特征在于，所述枢纽区是由两个或以上空间上分隔的铰链构成。
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Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES1165808Y (es) * 2016-08-11 2016-12-19 Partner Local Grup S L Cuello tubular de botella de cristal
WO2019144067A1 (en) * 2018-01-19 2019-07-25 West Pharmaceutical Services Deutschland Gmbh & CO.KG Closure device
WO2021069455A1 (en) 2019-10-08 2021-04-15 Becton Dickinson France Connector for connecting a medical injection device to a container and assembly comprising said connector and medical injection device
CN113208916A (zh) * 2020-01-21 2021-08-06 贝克顿·迪金森公司 药瓶适配器装置
CN213139759U (zh) * 2020-09-04 2021-05-07 汪祥海 一种液体注入器转接头
US11674614B2 (en) 2020-10-09 2023-06-13 Icu Medical, Inc. Fluid transfer device and method of use for same
TW202227034A (zh) * 2020-11-27 2022-07-16 丹麥商弗羅桑醫療設備公司 藥瓶配接器
USD1010112S1 (en) 2021-07-03 2024-01-02 KAIRISH INNOTECH Private Ltd. Vial adapter with valve

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005017985A1 (de) * 2005-04-19 2006-10-26 Theo Arnitz Verfahren und Vorrichtungen zum Auflösen von Medikamenten für Injektionen
CN100560046C (zh) * 2004-04-29 2009-11-18 麦迪麦珀医疗工程有限公司 液体药物医疗装置
CN102711712A (zh) * 2010-02-24 2012-10-03 麦迪麦珀医疗工程有限公司 具有通风布置的流体转移组合件
CN104755059A (zh) * 2012-08-26 2015-07-01 麦迪麦珀医疗工程有限公司 液体药物转移装置

Family Cites Families (775)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US247975A (en) 1881-10-04 James h
US62333A (en) 1867-02-26 Henry holl
US300060A (en) 1884-06-10 Isaac v
US254444A (en) 1882-02-28 Chaeles w
US1021681A (en) 1911-02-13 1912-03-26 John F Jennings Valve for corrosive liquids.
US1704817A (en) 1928-01-17 1929-03-12 Okadee Company Locomotive-cylinder cock
US1930944A (en) 1932-12-21 1933-10-17 Jr William L Schmitz Measuring dispenser
US2326490A (en) 1942-06-13 1943-08-10 Harold N Perelson Fluid dispenser
US2560162A (en) 1950-02-10 1951-07-10 Becton Dickinson Co Needle structure
US2748769A (en) 1953-02-24 1956-06-05 Huber Jennie Hypodermic needle
US2830587A (en) 1954-02-01 1958-04-15 Everett Samuel James Hypodermic needles
US3059643A (en) 1954-12-10 1962-10-23 Baxter Laboratories Inc Pumping apparatus
DE1064693B (de) 1956-03-08 1959-09-03 Josef Klinger Vorrichtung zum selbsttaetigen Einstechen einer Injektionsnadel
US2931668A (en) 1956-04-30 1960-04-05 Bastian Blessing Co Coupling
US2968497A (en) 1958-02-05 1961-01-17 Avro Aircraft Ltd Self-sealing coupling
US3225763A (en) 1962-06-18 1965-12-28 Chesebrough Ponds Medicinal injector
US3277893A (en) 1964-01-31 1966-10-11 Becton Dickinson Co Hypodermic projectile with barb in the cannula bevel
US3308822A (en) 1964-04-02 1967-03-14 Loretta Fontano Hypodermic needle
DE1945279U (de) 1966-07-02 1966-09-01 Gruenenthal Chemie Hilfsgeraet zur herstellung von sterilen loesungen.
FR2029242A5 (en) 1969-01-21 1970-10-16 Alriq Christian Self-perforable plug for bacteriological - culture tubes
DE1913926A1 (de) 1969-03-19 1970-09-24 Hoechst Ag Zweikammerspritze
US3757981A (en) 1969-11-24 1973-09-11 Harris R Valves and valve needle syringes
US3618637A (en) * 1970-02-04 1971-11-09 Deseret Pharma Rotary mixing valve
US3788524A (en) 1971-12-22 1974-01-29 Cutter Lab Additive container
US3826261A (en) 1971-12-27 1974-07-30 Upjohn Co Vial and syringe assembly
US3782365A (en) 1973-03-13 1974-01-01 S Pinna Detector for locating veins in living bodies
US3822700A (en) 1973-03-16 1974-07-09 M Pennington Intravenous solution dispenser
US4109670A (en) 1973-05-16 1978-08-29 Slagel Roger D Combination check flow control and selector valve
US3872992A (en) 1973-08-06 1975-03-25 Pharmaco Inc Medicament vial stopper piercing and needle positioning device
US3885607A (en) 1973-11-16 1975-05-27 Richard I Peltier Device for providing fluid communication between two sealed vessels
FR2268707B1 (zh) 1974-04-26 1976-12-17 Becton Dickinson France
US3977555A (en) 1974-05-07 1976-08-31 Pharmaco, Inc. Protective safety cap for medicament vial
US3938520A (en) 1974-06-10 1976-02-17 Abbott Laboratories Transfer unit having a dual channel transfer member
US3957052A (en) 1974-09-13 1976-05-18 Medical Development Corporation Pumping-syringe
US3980083A (en) * 1975-02-13 1976-09-14 Illinois Tool Works Inc. Medicament infusor unit
US3993063A (en) 1975-06-16 1976-11-23 Union Carbide Corporation Protective shielding assembly for use in loading a hypodermic syringe with radioactive material
US4051852A (en) 1975-06-26 1977-10-04 The Kendall Company Aspirating device
US4026128A (en) 1975-12-12 1977-05-31 Universal Textile Machine Corporation Faulty needle sensing
US3999543A (en) * 1976-02-06 1976-12-28 Illinois Tool Works Inc. Medicament additive system
US4020839A (en) 1976-02-26 1977-05-03 Parke, Davis & Company Medicament-dispensing package
USD247975S (en) 1976-07-30 1978-05-23 Luther Ronald B Catheterization needle
US4210173A (en) 1976-12-06 1980-07-01 American Hospital Supply Corporation Syringe pumping system with valves
USD248568S (en) 1976-12-13 1978-07-18 Aaron Ismach Animal intradermal nozzle for jet injection device
US4121585A (en) 1977-01-24 1978-10-24 Becker Jr Karl E Anti backflow injection device
DE2714094C3 (de) 1977-03-30 1980-04-17 Bayer Ag, 5090 Leverkusen Vorrichtung zur Bestimmung des Wassergehaltes von isotropen Materialien mit Hilfe der Mikrowellenabsorption
US4187848A (en) 1977-07-18 1980-02-12 The Kendall Company Adapter assembly
USD254444S (en) 1977-09-01 1980-03-11 Levine Robert A Blood sampling needle
US4161178A (en) 1977-12-08 1979-07-17 Abbott Laboratories Additive transfer device
US4203443A (en) 1977-12-08 1980-05-20 Abbott Laboratories Additive transfer unit with interlocking means
USD257286S (en) 1978-03-06 1980-10-07 Tronomed International, Inc. Medical valve
US4314586A (en) 1978-08-30 1982-02-09 Tronomed International, Inc. Disposable valve
US4639019A (en) 1979-06-04 1987-01-27 Baxter Travenol Laboratories, Inc. Luer connection
US4312349A (en) 1979-07-23 1982-01-26 Cohen Milton J Filter device for injectable fluid
US4296786A (en) 1979-09-28 1981-10-27 The West Company Transfer device for use in mixing a primary solution and a secondary or additive substance
US4253501A (en) 1979-11-09 1981-03-03 Ims Limited Transfer system
US4303067A (en) 1980-01-21 1981-12-01 American Hospital Supply Corporation Medical liquid bag having an improved additive port
US4328802A (en) 1980-05-14 1982-05-11 Survival Technology, Inc. Wet dry syringe package
US4376634A (en) 1980-05-30 1983-03-15 Mallinckrodt, Inc. Assay kit having syringe, dilution device and reagents within sealed container
USD267199S (en) 1980-07-17 1982-12-07 Abbott Laboratories Vial and solution container connecting device
USD268871S (en) 1980-09-18 1983-05-03 Alva Medical, Inc. Medical tubing hub for catheters or the like
USD270282S (en) 1980-10-09 1983-08-23 Abbott Laboratories Catheter insertion adapter
US4335717A (en) 1980-10-10 1982-06-22 Abbott Laboratories I.V. Administration set with retrograde volume
USD271421S (en) 1981-06-12 1983-11-15 Fetterman James W Medical valve
US4434823A (en) 1981-06-29 1984-03-06 American Hospital Supply Corporation Liquid transfer device
US4493348A (en) 1981-06-29 1985-01-15 Pur/Acc Corporation Method and apparatus for orally dispensing liquid medication
US4465471A (en) 1981-08-26 1984-08-14 Eli Lilly And Company Intravenous administration system for dry medicine
US4392850A (en) 1981-11-23 1983-07-12 Abbott Laboratories In-line transfer unit
US4410321A (en) 1982-04-06 1983-10-18 Baxter Travenol Laboratories, Inc. Closed drug delivery system
US4411662A (en) 1982-04-06 1983-10-25 Baxter Travenol Laboratories, Inc. Sterile coupling
US4475915A (en) 1982-05-07 1984-10-09 Sloane Glenn L Holder for a syringe and an ampoule
US4588396A (en) 1982-10-22 1986-05-13 Stroebel Maurice G Apparatus for gravity feed of liquid under constant hydrostatic pressure
USD280018S (en) 1982-10-25 1985-08-06 Commonwealth Industries Syringe loading guide
US4507113A (en) 1982-11-22 1985-03-26 Derata Corporation Hypodermic jet injector
US4752292A (en) 1983-01-24 1988-06-21 Icu Medical, Inc. Medical connector
US5688254A (en) 1983-01-24 1997-11-18 Icu Medical, Inc. Medical connector
US4505709A (en) 1983-02-22 1985-03-19 Froning Edward C Liquid transfer device
US4676530A (en) 1983-04-07 1987-06-30 Warner-Lambert Company Coupling assembly for use in fluid flow systems
EP0126718A3 (en) 1983-05-20 1985-10-23 Bengt Gustavsson A device for transferring a substance from one vessel to another and further to the intended application
US4778447A (en) 1983-05-20 1988-10-18 Travenol European Research & Development Center Connectors
JPS6026391U (ja) 1983-07-30 1985-02-22 株式会社ハーマン 管接続具
US4532969A (en) 1983-09-21 1985-08-06 Kwaan Hau C Fluid withdrawal and instillation device
US4573993A (en) 1983-09-29 1986-03-04 Instafil, Inc. Fluid transfer apparatus
USD284603S (en) 1983-11-25 1986-07-08 Loignon Edward G Syphon fitting
US4743243A (en) 1984-01-03 1988-05-10 Vaillancourt Vincent L Needle with vent filter assembly
IT1173370B (it) 1984-02-24 1987-06-24 Erba Farmitalia Dispositivo di sicurezza per collegare una siringa alla imboccatura di un flacone contenente un farmaco o di un tubicino per l'erogazione del farmaco della siringa
US4585446A (en) 1984-03-16 1986-04-29 Joseph Kempf Dialysis needle
US4581014A (en) 1984-04-03 1986-04-08 Ivac Corporation Fluid infusion system
US5088996A (en) 1984-04-16 1992-02-18 Kopfer Rudolph J Anti-aerosoling drug reconstitution device
US4697622A (en) 1984-06-01 1987-10-06 Parker Hannifin Corporation Passive filling device
US4588403A (en) 1984-06-01 1986-05-13 American Hospital Supply Corporation Vented syringe adapter assembly
US4604093A (en) 1984-06-12 1986-08-05 I-Flow Corporation Apparatus and method for administering multiple fluid infusions
US5113904A (en) 1984-07-13 1992-05-19 Aslanian Jerry L Flow control device for administration of intravenous fluids
US4607671A (en) 1984-08-21 1986-08-26 Baxter Travenol Laboratories, Inc. Reconstitution device
JPS6168045A (ja) 1984-09-10 1986-04-08 テルモ株式会社 医療用活栓
US4759756A (en) 1984-09-14 1988-07-26 Baxter Travenol Laboratories, Inc. Reconstitution device
US4614437A (en) 1984-11-02 1986-09-30 Dougherty Brothers Company Mixing container and adapter
USD300060S (en) 1985-02-25 1989-02-28 William Cook Europe A/S Biopsy cannula
SE8501656D0 (sv) 1985-04-03 1985-04-03 Mediplast Ab Overforingsanordning
US4721133A (en) 1985-09-26 1988-01-26 Alcon Laboratories, Inc. Multiple use valving device
US4675020A (en) 1985-10-09 1987-06-23 Kendall Mcgaw Laboratories, Inc. Connector
US4667927A (en) 1985-11-08 1987-05-26 Rao Medical Devices, Inc. Liquid flow metering device
DE3600496A1 (de) 1986-01-10 1987-07-16 Josef Magasi Punktionskanuele, deren griff sowie verfahren zu deren herstellung
US4865592A (en) 1986-02-20 1989-09-12 Becton, Dickinson And Company Container and needle assembly
US4834152A (en) 1986-02-27 1989-05-30 Intelligent Medicine, Inc. Storage receptacle sealing and transfer apparatus
US4735608A (en) 1986-05-14 1988-04-05 Del F. Kahan Apparatus for storing and reconstituting antibiotics with intravenous fluids
US5049129A (en) 1986-05-29 1991-09-17 Zdeb Brian D Adapter for passive drug delivery system
USD303013S (en) 1986-06-19 1989-08-22 Pacesetter Infusion, Ltd. Female luer connector
SE461765B (sv) 1986-07-10 1990-03-26 Haessle Ab Anordning foer frisaettning av substans
IT1201801B (it) 1986-08-04 1989-02-02 Pietro Cosmai Caricatore miscelatore per iniettori transcutanei
IE60235B1 (en) 1986-09-18 1994-06-15 Kabi Pharmacia Ab "Connector and disposable assembly utilising said connector"
US4743229A (en) 1986-09-29 1988-05-10 Collagen Corporation Collagen/mineral mixing device and method
US4683975A (en) 1986-09-30 1987-08-04 General Motors Corporation Vehicle power window control
US4797898A (en) 1986-11-21 1989-01-10 Racal Data Communications Inc. Method and apparatus for equalization of data transmission system
US4832690A (en) 1987-01-23 1989-05-23 Baxter International Inc. Needle-pierceable cartridge for drug delivery
US4729401A (en) 1987-01-29 1988-03-08 Burron Medical Inc. Aspiration assembly having dual co-axial check valves
US5041105A (en) 1987-03-03 1991-08-20 Sherwood Medical Company Vented spike connection component
US4787898A (en) 1987-05-12 1988-11-29 Burron Medical Inc. Vented needle with sideport
US4758235A (en) 1987-05-26 1988-07-19 Tu Ho C Cardiopulmonary resuscitation medication assembly
AU101237S (en) 1987-06-18 1988-09-08 Ab Astra Transfer cannula
US5178607A (en) 1987-07-31 1993-01-12 Lynn Lawrence A Blood aspiration assembly septum and blunt needle aspirator
IT211830Z2 (it) 1987-09-22 1989-05-25 Farmitalia Carl Erba S P A Dispositivo di sicurezza perl'introduzione ed il prelievo di liquidi in e da flaconi di farmaci e simili.
US4804366A (en) 1987-10-29 1989-02-14 Baxter International Inc. Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system
USD314050S (en) 1987-11-27 1991-01-22 Terumo Kabushiki Kaisha Medical connector
US4919596A (en) 1987-12-04 1990-04-24 Pacesetter Infusion, Ltd. Fluid delivery control and monitoring apparatus for a medication infusion system
US5211638A (en) 1988-01-25 1993-05-18 Baxter International Inc. Pre-slit injection site
DE3804429A1 (de) 1988-02-12 1989-08-24 Schleicher & Schuell Gmbh Einmalfilter
US4857062A (en) 1988-03-09 1989-08-15 Medical Parameters, Inc. Catheter introducer valve
US4932944A (en) 1988-03-09 1990-06-12 The University Of Virginia Alumni Patents Foundation Intravenous port injection and connector system
US4931040A (en) 1988-04-13 1990-06-05 Habley Medical Technology Safety syringe having a combination needle cannula and articulating hub for retracting said cannula into a medication carpule
US4871463A (en) 1988-08-23 1989-10-03 Sepratech Vertical reaction vessel
US4898209A (en) 1988-09-27 1990-02-06 Baxter International Inc. Sliding reconstitution device with seal
US6344031B1 (en) 1989-03-22 2002-02-05 Laurel A. Novacek Safety syringe needle device with interchangeable and retractable needle platform
US5122124A (en) 1988-12-14 1992-06-16 Patco Ventures Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US5301685A (en) 1989-01-10 1994-04-12 Guirguis Raouf A Method and apparatus for obtaining a cytology monolayer
US5035686A (en) 1989-01-27 1991-07-30 C. R. Bard, Inc. Catheter exchange system with detachable luer fitting
USD328788S (en) 1989-05-01 1992-08-18 Terumo Kabushiki Kaisha Connector for catheter
US5135492A (en) 1989-06-26 1992-08-04 University Of Florida Arterial/venous fluid transfer system
USD341420S (en) 1989-07-14 1993-11-16 Ivac Corporation Combined universal spike and drip chamber
US4967797A (en) 1989-08-16 1990-11-06 Manska Wayne E Tap valve
US5053015A (en) 1989-08-30 1991-10-01 The Kendall Company Locking catheter adapter
US4997430A (en) 1989-09-06 1991-03-05 Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En Infusievloeistoffen B.V. Method of and apparatus for administering medicament to a patient
AU629385B2 (en) * 1989-09-12 1992-10-01 F.H. Faulding & Co. Limited Bipartite injector device
US5578015A (en) 1989-09-18 1996-11-26 Robb Pascal Patent Limited Safety syringe incorporating automatic needle holder release
DE69012803T2 (de) 1990-01-08 1995-04-06 Becton Dickinson France Aufbewahrungs- und umfüllflasche mit doppelter kammer.
US5304163A (en) 1990-01-29 1994-04-19 Baxter International Inc. Integral reconstitution device
US5125915A (en) 1990-03-02 1992-06-30 Cardiopulmonics, Inc. Locking y-connector for selective attachment to exterior of medical tubing
US5061248A (en) 1990-04-04 1991-10-29 Sacco John J Injection port safety shield
US5006114A (en) 1990-04-20 1991-04-09 Rogers Bobby E Medical valve assembly
USRE38996E1 (en) 1990-04-20 2006-02-28 Becton, Dickinson And Company Needle tip cover
US5104387A (en) 1990-05-25 1992-04-14 St. Jude Medical, Inc. Bi-planar fluid control valve
US5045066A (en) 1990-06-07 1991-09-03 Smith & Nephew, Inc. Dental needle with stick resistant protective sleeve
US5203775A (en) 1990-09-18 1993-04-20 Medex, Inc. Needleless connector sample site
US5515871A (en) 1990-09-28 1996-05-14 Sulzer Brothers Ltd. Hollow needle for medical use and a laser method for manufacturing
US5125908A (en) 1990-10-19 1992-06-30 Cohen Milton J Hypodermic syringe with protective holder
US5201717A (en) 1990-12-05 1993-04-13 Philip Wyatt Safety enclosure
US5232029A (en) 1990-12-06 1993-08-03 Abbott Laboratories Additive device for vial
JP3066611B2 (ja) 1991-04-30 2000-07-17 武田薬品工業株式会社 個別密封容器に収容した２種薬剤の無菌保持混合装置
US5183469A (en) 1991-05-10 1993-02-02 Becton, Dickinson And Company Device for the removal and replacement of a needle shield
DE4122221A1 (de) 1991-07-04 1993-03-18 Axel Von Brand Transfer- und entnahmespike
DE4122476A1 (de) 1991-07-06 1993-01-07 Leopold Pharma Gmbh Verfahren und vorrichtung zum ueberleiten von zwei oder mehr sterilen fluessigkeiten im geschlossenen system
US5288290A (en) 1991-09-25 1994-02-22 Alcon Surgical, Inc. Multi-ported valve assembly
US5242432A (en) 1991-09-26 1993-09-07 Ivac Needleless adapter
WO1993010001A1 (en) 1991-11-21 1993-05-27 Gds Technology, Inc. Fluid transfer device
US5171230A (en) 1991-11-29 1992-12-15 Medex, Inc. Fast flush catheter valve
US5304165A (en) 1991-12-09 1994-04-19 Habley Medical Technology Corporation Syringe-filling medication dispenser
US5247972A (en) 1991-12-17 1993-09-28 Whittier Medical, Inc. Alignment guide for hypodermic syringe
CA2124822C (en) 1991-12-18 2007-07-03 George A. Lopez Medical valve
US5279597A (en) 1992-01-13 1994-01-18 Arrow International Investment Corp. Catheter compression clamp
CA2093560C (en) 1992-04-10 2005-06-07 Minoru Honda Fluid container
US5328474A (en) 1992-04-13 1994-07-12 B. Braun Medical Inc. Tamper resistant syringe cap
JP2605345Y2 (ja) 1992-05-01 2000-07-10 株式会社大塚製薬工場 薬剤容器
JPH05317383A (ja) 1992-05-19 1993-12-03 Nissho Corp 薬剤容器との連通手段を備えた溶解液容器
US5279576A (en) 1992-05-26 1994-01-18 George Loo Medication vial adapter
US5232109A (en) 1992-06-02 1993-08-03 Sterling Winthrop Inc. Double-seal stopper for parenteral bottle
USD349648S (en) 1992-06-02 1994-08-16 Sterling Winthrop Inc. Closure for vials
GB9211912D0 (en) 1992-06-04 1992-07-15 Drg Flexpak Ltd Vial connector system
JPH0686738U (ja) 1992-06-16 1994-12-20 森下ルセル株式会社 医療用容器
USD357733S (en) 1992-07-28 1995-04-25 Pall Corporation Spike detector
US5300034A (en) 1992-07-29 1994-04-05 Minnesota Mining And Manufacturing Company Iv injection site for the reception of a blunt cannula
ZA935733B (en) 1992-08-07 1994-06-06 West Co Needleless access stopper
DE9210674U1 (zh) 1992-08-07 1993-07-22 B. Braun Melsungen Ag, 34212 Melsungen, De
US5308483A (en) 1992-08-27 1994-05-03 Gelman Sciences Inc. Microporous filtration funnel assembly
US5344417A (en) 1992-09-11 1994-09-06 Becton, Dickinson And Company Universal fitting for inoculation receptacles
US5334163A (en) 1992-09-16 1994-08-02 Sinnett Kevin B Apparatus for preparing and administering a dose of a fluid mixture for injection into body tissue
US5603706A (en) 1992-09-29 1997-02-18 Wyatt; Philip Infusion apparatus
US5334179A (en) 1992-10-16 1994-08-02 Abbott Laboratories Latching piercing pin for use with fluid vials of varying sizes
US5562696A (en) 1992-11-12 1996-10-08 Cordis Innovasive Systems, Inc. Visualization trocar
US5547471A (en) 1992-11-19 1996-08-20 Baxter International Inc. In-line drug delivery device for use with a standard IV administration set and a method for delivery
US5385547A (en) 1992-11-19 1995-01-31 Baxter International Inc. Adaptor for drug delivery
US5496274A (en) 1992-11-23 1996-03-05 Becton, Dickinson And Company Locking safety needle assembly
JPH07506287A (ja) 1992-12-15 1995-07-13 メイエール，ガブリエル 薬用物質から溶液，懸濁液，又はエマルジョンを調製する装置
JP2604240Y2 (ja) 1992-12-25 2000-04-24 川澄化学工業株式会社 医療用具
US5405333A (en) 1992-12-28 1995-04-11 Richmond; Frank M. Liquid medicament bag with needleless connector fitting using boat assembly
JPH06239352A (ja) 1993-02-05 1994-08-30 Nissho Corp 溶解液注入セット
US5766211A (en) 1993-02-08 1998-06-16 Wood; Jan Medical device for allowing insertion and drainage into a body cavity
US5269768A (en) 1993-02-08 1993-12-14 Smiths Industries Medical Systems, Inc. Valved suction catheter
US5464111A (en) 1993-03-03 1995-11-07 Sterling Winthrop Closure for medication container
US5312377A (en) 1993-03-29 1994-05-17 Dalton Michael J Tapered luer connector
US5591143A (en) 1993-04-02 1997-01-07 Medrad Inc. Luer connector with torque indicator
US5364386A (en) 1993-05-05 1994-11-15 Hikari Seiyaku Kabushiki Kaisha Infusion unit
US5607439A (en) 1993-06-24 1997-03-04 Yoon; Inbae Safety penetrating instrument with penetrating member moving during penetration and triggered safety member protrusion
CA2124970A1 (en) 1993-06-29 1994-12-30 R. Hayes Helgren Pointed adapter for blunt entry device
US5429614A (en) 1993-06-30 1995-07-04 Baxter International Inc. Drug delivery system
US5445630A (en) 1993-07-28 1995-08-29 Richmond; Frank M. Spike with luer fitting
US5364387A (en) 1993-08-02 1994-11-15 Becton, Dickinson And Company Drug access assembly for vials and ampules
US5397303A (en) 1993-08-06 1995-03-14 River Medical, Inc. Liquid delivery device having a vial attachment or adapter incorporated therein
US5451374A (en) 1993-08-23 1995-09-19 Incutech, Inc. Medicine vessel stopper
US6146362A (en) 1993-08-27 2000-11-14 Baton Development, Inc. Needleless IV medical delivery system
US5827262A (en) 1993-09-07 1998-10-27 Debiotech S.A. Syringe device for mixing two compounds
SE9303178D0 (sv) 1993-09-29 1993-09-29 Kabi Pharmacia Ab Improvements in injection cartridges
US5699821A (en) 1993-10-13 1997-12-23 Paradis; Joseph R. Control of fluid flow
US5509433A (en) 1993-10-13 1996-04-23 Paradis; Joseph R. Control of fluid flow
US5806831A (en) 1993-10-13 1998-09-15 Paradis; Joseph R. Control of fluid flow with internal cannula
US5472022A (en) 1993-11-02 1995-12-05 Genentech, Inc. Injection pen solution transfer apparatus and method
US5348544A (en) 1993-11-24 1994-09-20 Becton, Dickinson And Company Single-handedly actuatable safety shield for needles
US5549577A (en) 1993-12-29 1996-08-27 Ivac Corporation Needleless connector
US5522804A (en) * 1994-02-15 1996-06-04 Lynn; Lawrence A. Aspiration, mixing, and injection syringe
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5658133A (en) 1994-03-09 1997-08-19 Baxter International Inc. Pump chamber back pressure dissipation apparatus and method
US5554128A (en) 1994-03-09 1996-09-10 Joseph K. Andonian Syringe and vial connector
US5520659A (en) 1994-03-09 1996-05-28 Joseph K. Andonian Syringe needle cover and vial connector
US5482446A (en) 1994-03-09 1996-01-09 Baxter International Inc. Ambulatory infusion pump
US5454805A (en) 1994-03-14 1995-10-03 Brony; Seth K. Medicine vial link for needleless syringes
US5462317A (en) 1994-03-23 1995-10-31 Keller; Wilhelm A. Adapter for a mixing or dispensing device
US5527306A (en) 1994-04-18 1996-06-18 Haining; Michael L. Vial adapter
USD362718S (en) 1994-04-22 1995-09-26 Mcgaw, Inc. Turn lock cannula
DE4414697C2 (de) 1994-04-27 1998-06-18 Caremed Vertriebsgesellschaft Vorrichtung zum Transferieren und Entnehmen von Flüssigkeiten aus Flaschen, Beuteln oder ähnlichen Behältnissen für medizinische Zwecke
US5746733A (en) 1994-05-19 1998-05-05 Becton, Dickinson And Company Syringe filling and delivery device
US5832971A (en) 1994-05-19 1998-11-10 Becton, Dickinson And Company Syringe filling and delivery device
ES2119446T3 (es) 1994-05-23 1998-10-01 Liposome Co Inc Dispositivo de preparacion de formulacion.
US5649637A (en) 1994-06-02 1997-07-22 Automatic Liquid Packaging, Inc. Torque-resistant closure for a hermetically sealed container
JP3456019B2 (ja) 1994-06-17 2003-10-14 ニプロ株式会社 液体導入針およびそれを用いた乾燥製剤溶解補助具
US5470319A (en) 1994-06-20 1995-11-28 Critical Device Corporation Needleless injection site
US6183448B1 (en) 1994-06-20 2001-02-06 Bruno Franz P. Mayer Needleless injection site
PT771184E (pt) 1994-06-24 2002-11-29 Icu Medical Inc Dispositivo de transferencia de fluidos e metodo de utilizacao
EP0692235A1 (en) 1994-07-14 1996-01-17 International Medication Systems (U.K.) Ltd. Mixing & dispensing apparatus
US5526853A (en) 1994-08-17 1996-06-18 Mcgaw, Inc. Pressure-activated medication transfer system
GB9419316D0 (en) 1994-09-24 1994-11-09 Robertson William F A needle guard
FR2726768A1 (fr) 1994-11-14 1996-05-15 Debiotech Sa Dispositif de seringue fixable sur un flacon
GB9425642D0 (en) 1994-12-20 1995-02-22 Weston Medical Ltd Filling device
US6681810B2 (en) 1994-12-20 2004-01-27 Aradigm Corporation Filling device for a needleless injector cartridge
US5531695A (en) 1994-12-22 1996-07-02 Sherwood Medical Company Tamper evident sleeve
US5616136A (en) 1995-01-09 1997-04-01 Med-Safe Systems, Inc. Quick release needle removal apparatus
US5653686A (en) 1995-01-13 1997-08-05 Coulter Corporation Closed vial transfer method and system
USD369406S (en) 1995-01-13 1996-04-30 Sanofi Winthrop, Inc. Cannula
US5492147A (en) 1995-01-17 1996-02-20 Aeroquip Corporation Dry break coupling
GB9501218D0 (en) 1995-01-21 1995-03-15 Boc Group Plc Medical devices
US5647845A (en) 1995-02-01 1997-07-15 Habley Medical Technology Corporation Generic intravenous infusion system
US5674195A (en) 1995-02-06 1997-10-07 Truthan; Charles Edwin Syringe apparatus and method of mixing liquid medicants within a syringe
DE19504413A1 (de) 1995-02-10 1996-08-22 Pharmacia Gmbh Überleitungsgerät
DE19506163C2 (de) 1995-02-22 1998-01-29 Hans Mueller Vorrichtung zur Behandlung von Blut
US5584819A (en) 1995-03-13 1996-12-17 Kopfer; Rudolph J. Nested blunt/sharp injection assembly
IL114960A0 (en) 1995-03-20 1995-12-08 Medimop Medical Projects Ltd Flow control device
US5651776A (en) 1995-03-22 1997-07-29 Angiodynamics, Inc. Luer-type connector
EP0765853B1 (en) 1995-04-04 1999-07-07 Kuraray Co., Ltd. Process for preparing 6-methylheptan-2-one
US5566729A (en) 1995-04-06 1996-10-22 Abbott Laboratories Drug reconstitution and administration system
DE19513666C1 (de) 1995-04-11 1996-11-28 Behringwerke Ag Vorrichtung zum Zusammenführen einer ersten flüssigen und einer zweiten festen oder flüssigen Komponente mittels Unterdruck unter sterilen Bedingungen
US5902280A (en) 1995-04-13 1999-05-11 Advanced Cytometrix, Inc. Aspiration needle apparatus incorporating its own vacuum and method and adapter for use therewith
US5562686A (en) 1995-04-19 1996-10-08 United States Surgical Corporation Apparaus and method for suturing body tissue
US5968022A (en) 1995-04-28 1999-10-19 Saito; Yoshikuni Medical hollow needle and method of production
SE509950C2 (sv) 1995-05-02 1999-03-29 Carmel Pharma Ab Anordning för administrering av toxisk vätska
US5839715A (en) 1995-05-16 1998-11-24 Alaris Medical Systems, Inc. Medical adapter having needleless valve and sharpened cannula
NZ286445A (en) 1995-05-16 1997-12-19 Ivac Corp Needleless luer connector: deformable piston occludes bore
US5685845A (en) 1995-07-11 1997-11-11 Becton, Dickinson And Company Sterile resealable vial connector assembly
US5616203A (en) 1995-07-14 1997-04-01 Merit Medical Method of manufacturing a split ring airless rotatable connector
USD388172S (en) 1995-07-27 1997-12-23 E-Z Kare Good Health Systems, Inc. Nasal dilator
JPH0956782A (ja) 1995-08-24 1997-03-04 Kanae:Kk 受動的薬剤放出用具
FR2738550B1 (fr) 1995-09-11 1997-11-07 Biodome Dispositif d'obturation d'un recipient lui-meme ferme, ensemble pour dispenser un produit comprenant un tel recipient et un tel dispositif d'obturation
IE77523B1 (en) 1995-09-11 1997-12-17 Elan Med Tech Medicament delivery device
US5702019A (en) 1995-09-27 1997-12-30 Becton Dickinson France S.A. Vial having resealable membrane assembly activated by a medical delivery device
CA2185494A1 (en) 1995-09-27 1997-03-28 Jean-Pierre Grimard Resealable vial with connector assembly having a membrane and pusher
US5989221A (en) 1995-10-20 1999-11-23 Pharmacia & Upjohn Ab Arrangement in electronically controlled injection devices
PT957883E (pt) 1995-10-20 2003-07-31 Schering Ag Adaptador para extrair um liquido de um receptaculo fechado por um tampao
US5611576A (en) 1995-11-24 1997-03-18 Industrie Borla Spa Female coupling element for haemodialysis medical equipment
US5833213A (en) 1995-12-29 1998-11-10 Rymed Technologies, Inc. Multiple dose drug vial adapter for use with a vial having a pierceable septum and a needleless syringe
DE69712499T2 (de) 1996-01-11 2002-11-14 Duoject Inc Abgabesystem für in pharmazeutischen phiolen verpackte arzneimittel
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
US5879337A (en) 1997-02-27 1999-03-09 Injectimed, Inc. Needle tip guard for hypodermic needles
US6629959B2 (en) 1996-02-27 2003-10-07 Injectimed, Inc. Needle tip guard for percutaneous entry needles
US5810792A (en) 1996-04-03 1998-09-22 Icu Medical, Inc. Locking blunt cannula
USD393722S (en) 1996-04-04 1998-04-21 Icu Medical, Inc. Locking blunt cannula
CA2252404A1 (en) 1996-04-22 1997-10-30 Abbott Laboratories Container closure system
GB9609563D0 (en) 1996-05-08 1996-07-10 Sterimatic Holdings Ltd Venting devices
DE19619026A1 (de) 1996-05-10 1997-11-13 Trinova Gmbh Schnellkupplung
US5752942A (en) 1996-06-20 1998-05-19 Becton Dickinson And Company Five beveled point geometry for a hypodermic needle
US5897526A (en) 1996-06-26 1999-04-27 Vaillancourt; Vincent L. Closed system medication administering system
US5728087A (en) 1996-07-30 1998-03-17 Bracco Diagnostics, Inc. Universal flexible plastic container with multiple access ports of inverted Y shape configuration
US6296621B1 (en) 1996-08-23 2001-10-02 Baxter International Inc. Receptacle for passive drug delivery
US5871110A (en) 1996-09-13 1999-02-16 Grimard; Jean-Pierre Transfer assembly for a medicament container having a splashless valve
CA2211629A1 (en) 1996-09-17 1998-03-17 Bernard Sams Vial connector assembly for a medicament container
US5873872A (en) 1996-09-17 1999-02-23 Becton Dickinson And Company Multipositional resealable vial connector assembly for efficient transfer of liquid
FR2753624B1 (fr) 1996-09-25 1999-04-16 Biodome Dispositif de connexion, en particulier entre un recipient avec bouchon perforable et une seringue
US5738144A (en) 1996-10-11 1998-04-14 Aeroquip Corporation Luer connecting coupling
US5817082A (en) 1996-11-08 1998-10-06 Bracco Diagnostics Inc. Medicament container closure with integral spike access means
US5895383A (en) 1996-11-08 1999-04-20 Bracco Diagnostics Inc. Medicament container closure with recessed integral spike access means
US5941848A (en) 1996-11-14 1999-08-24 Baxter International Inc. Passive drug delivery apparatus
US6883778B1 (en) 1996-11-18 2005-04-26 Nypro Inc. Apparatus for reducing fluid drawback through a medical valve
WO1998022178A1 (en) 1996-11-18 1998-05-28 Nypro, Inc. Swabbable luer-coned valve
US5868710A (en) 1996-11-22 1999-02-09 Liebel Flarsheim Company Medical fluid injector
US6004278A (en) 1996-12-05 1999-12-21 Mdc Investment Holdings, Inc. Fluid collection device with retractable needle
FR2756811B1 (fr) 1996-12-06 1999-02-05 Valois Dispositif de distribution de produit fluide du type bicomposant
GB9700177D0 (en) 1997-01-07 1997-02-26 Nycomed Imaging As Container
GB9701413D0 (en) 1997-01-24 1997-03-12 Smithkline Beecham Biolog Novel device
US5924584A (en) 1997-02-28 1999-07-20 Abbott Laboratories Container closure with a frangible seal and a connector for a fluid transfer device
US5954104A (en) 1997-02-28 1999-09-21 Abbott Laboratories Container cap assembly having an enclosed penetrator
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
USD405522S (en) 1997-04-18 1999-02-09 Vital Signs Inc. Breathing tube for conveying oxygen or anesthesia gas to lungs and conveying exhaled gas away from lungs of patient
US5911710A (en) 1997-05-02 1999-06-15 Schneider/Namic Medical insertion device with hemostatic valve
US6530900B1 (en) 1997-05-06 2003-03-11 Elan Pharma International Limited Drug delivery device
US5772652A (en) 1997-05-14 1998-06-30 Comar, Inc. Stab cap for a vial having a puncturable seal
US6042433A (en) 1997-05-29 2000-03-28 The Whitaker Corporation Electrical contact
JPH1147274A (ja) 1997-06-03 1999-02-23 Takeda Chem Ind Ltd ２室型注射器及び２室型注射器用接続具
IT1293856B1 (it) 1997-06-27 1999-03-10 Borla Ind Dispositivo trasduttore-protettore per linee biomedicali di emodialisi
US5755696A (en) 1997-06-30 1998-05-26 Becton, Dickinson And Company Syringe filling and delivery device
US5899468A (en) 1997-07-02 1999-05-04 Rehrig Pacific Company Organic waste cart with vented lid
US5820621A (en) 1997-07-29 1998-10-13 Becton, Dickinson And Company Medical fluid transfer and delivery device
JPH11104215A (ja) 1997-08-12 1999-04-20 Becton Dickinson Fr Sa ガラス瓶コネクタアセンブリ
US7125397B2 (en) 1997-08-20 2006-10-24 B. Braun Melsungen Ag Protective device for an injection needle
IL121605A (en) 1997-08-22 2001-03-19 Medimop Medical Projects Ltd Fluid access assembly and a method for preparing a liquid drug
US5834744A (en) 1997-09-08 1998-11-10 The Rubbright Group Tubular microwave applicator
US5919182A (en) 1997-09-12 1999-07-06 Becton, Dickinson And Company Medical fluid transfer and delivery device
US6036171A (en) 1997-09-17 2000-03-14 Halkey-Roberts Corporation Swabbable valve assembly
US6089541A (en) 1998-09-10 2000-07-18 Halkey-Roberts Corporation Valve having a valve body and a deformable stem therein
US5925029A (en) 1997-09-25 1999-07-20 Becton, Dickinson And Company Method and apparatus for fixing a connector assembly onto a vial with a crimp cap
US6090093A (en) 1997-09-25 2000-07-18 Becton Dickinson And Company Connector assembly for a vial having a flexible collar
US5944700A (en) 1997-09-26 1999-08-31 Becton, Dickinson And Company Adjustable injection length pen needle
US5935112A (en) 1997-10-15 1999-08-10 Stevens; Brian W. Hemostasis valve with catheter/guidewire seals
US5902298A (en) 1997-11-07 1999-05-11 Bracco Research Usa Medicament container stopper with integral spike access means
USD399559S (en) 1997-11-12 1998-10-13 Incutech, Inc. Pediatric catheter connector
IT236233Y1 (it) 1997-11-26 2000-08-08 Eurospital S P A Dispositivo per il collegamento di un contenitore di prodottofarmaceutico ad una sacca di prodotto liquido per effettuare il
US6159192A (en) 1997-12-04 2000-12-12 Fowles; Thomas A. Sliding reconstitution device with seal
US6457488B2 (en) 1998-01-08 2002-10-01 George Loo Stopcock having axial port for syringe twist actuation
US6179822B1 (en) 1998-01-20 2001-01-30 Bracco Research Usa Single use universal access device/medical container assembly
US6179823B1 (en) 1998-01-20 2001-01-30 Bracco Research Usa Multiple use universal connector flexible medical container assembly
FR2773735B1 (fr) 1998-01-20 2000-02-25 Becton Dickinson France Dispositif de confinement etanche
US6096011A (en) 1998-01-29 2000-08-01 Medrad, Inc. Aseptic connector and fluid delivery system using such an aseptic connector
US6681946B1 (en) 1998-02-26 2004-01-27 Becton, Dickinson And Company Resealable medical transfer set
US6382442B1 (en) 1998-04-20 2002-05-07 Becton Dickinson And Company Plastic closure for vials and other medical containers
US6003566A (en) 1998-02-26 1999-12-21 Becton Dickinson And Company Vial transferset and method
US6080132A (en) 1998-02-27 2000-06-27 Abbott Laboratories Apparatus for altering characteristics of a fluid
US6221065B1 (en) 1998-04-03 2001-04-24 Filtertek Inc. Self-priming needle-free “Y”-adapter
US6378714B1 (en) 1998-04-20 2002-04-30 Becton Dickinson And Company Transferset for vials and other medical containers
US6957745B2 (en) 1998-04-20 2005-10-25 Becton, Dickinson And Company Transfer set
US6209738B1 (en) 1998-04-20 2001-04-03 Becton, Dickinson And Company Transfer set for vials and medical containers
USD422357S (en) 1998-05-04 2000-04-04 Bracco Research Usa Stopper for medication container
US6692478B1 (en) 1998-05-04 2004-02-17 Paradis Joseph R Swabbable needleless vial access
US5921419A (en) 1998-05-04 1999-07-13 Bracco Research Usa Universal stopper
US6117114A (en) 1998-05-07 2000-09-12 Paradis; Joseph R. Swabbable needleless valve adaptations
USD410740S (en) 1998-05-11 1999-06-08 Incutech, Inc. Pediatric catheter connector
CA2262477C (en) 1998-05-16 2008-02-12 Bracco International B.V. Multiple use universal stopper
BR9910754A (pt) 1998-05-29 2001-07-03 Lawrence A Lynn Receptor luer e método para transferência de fluido
US5941850A (en) 1998-06-29 1999-08-24 Shah; Binod Safety cannula
US6245044B1 (en) 1998-07-17 2001-06-12 Becton, Dickinson And Company Variable extension combined spinal/epidural needle set and method for its use
US6358236B1 (en) 1998-08-06 2002-03-19 Baxter International Inc. Device for reconstituting medicaments for injection
US6276568B1 (en) 1998-08-21 2001-08-21 Pharmacia & Upjohn Company Spray bottle grip
GB2359754B (en) 2000-03-03 2004-04-28 Nmt Group Plc Needle sheath
US7074216B2 (en) 1998-09-15 2006-07-11 Baxter International Inc. Sliding reconstitution device for a diluent container
AR021220A1 (es) 1998-09-15 2002-07-03 Baxter Int DISPOSITIVO DE CONEXIoN PARA ESTABLECER UNA COMUNICACIoN FLUíDA ENTRE UN PRIMER RECIPIENTE Y UN SEGUNDO RECIPIENTE.
US6113583A (en) 1998-09-15 2000-09-05 Baxter International Inc. Vial connecting device for a sliding reconstitution device for a diluent container
US20050137566A1 (en) 2003-12-23 2005-06-23 Fowles Thomas A. Sliding reconstitution device for a diluent container
FR2783808B1 (fr) 1998-09-24 2000-12-08 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US6726672B1 (en) 1998-09-28 2004-04-27 Icu Medical, Inc. Intravenous drug access system
US6113068A (en) 1998-10-05 2000-09-05 Rymed Technologies Swabbable needleless injection port system having low reflux
USD430291S (en) 1998-10-08 2000-08-29 Becton, Dickinson And Company Medical container
USD431864S (en) 1998-11-24 2000-10-10 Becton Dickinson And Company Tamper evident cap for a tip cap
USD427308S (en) 1999-01-22 2000-06-27 Medimop Medical Projects Ltd. Vial adapter
US6364866B1 (en) 1999-01-22 2002-04-02 Douglas Furr Syringe loading aid
FR2789369B1 (fr) 1999-02-10 2001-04-27 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
EP1034809A1 (en) 1999-02-26 2000-09-13 F. Hoffmann-La Roche Ag Administering device for medication
USD445895S1 (en) 1999-03-05 2001-07-31 Maersk Medical A/S Funnel for a catheter
JP2000262497A (ja) 1999-03-16 2000-09-26 Sekisui Chem Co Ltd 分注器具、分注システム及び分注方法
FR2790948B1 (fr) 1999-03-18 2001-06-22 Sedat Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une capsule
US6099511A (en) 1999-03-19 2000-08-08 Merit Medical Systems, Inc. Manifold with check valve positioned within manifold body
USD427309S (en) 1999-04-30 2000-06-27 Incutech, Inc. Pediatric catheter connector
US6231552B1 (en) 1999-05-04 2001-05-15 Saf-T-Med, Inc. Threaded latching mechanism
US6092692A (en) 1999-05-10 2000-07-25 Riskin; Jane G. Medication applicator with incident reminder system
US6156025A (en) 1999-06-17 2000-12-05 Bracco Research Usa Inc. Twist valve
JP4329954B2 (ja) 1999-06-29 2009-09-09 東洋ゴム工業株式会社 空気入りタイヤ
US6706022B1 (en) 1999-07-27 2004-03-16 Alaris Medical Systems, Inc. Needleless medical connector with expandable valve mechanism
USD428141S (en) 1999-08-04 2000-07-11 Pharmacia & Upjohn Company Spray bottle grip
US6348044B1 (en) 1999-10-12 2002-02-19 George D. N. Coletti Method and apparatus for recapping single-use hypodermic needles
JP4236842B2 (ja) 1999-10-22 2009-03-11 アンタレス・ファーマ・インコーポレーテッド 医療用注射器及びそれと共に用いる医薬装填システム
US7198618B2 (en) 1999-11-04 2007-04-03 Tyco Healthcare Group Lp Safety shield for medical needles
US6253804B1 (en) 1999-11-05 2001-07-03 Minimed Inc. Needle safe transfer guard
US6453956B2 (en) 1999-11-05 2002-09-24 Medtronic Minimed, Inc. Needle safe transfer guard
FR2800713B1 (fr) 1999-11-05 2002-01-04 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US6632201B1 (en) 1999-11-17 2003-10-14 Baxter International Inc. Locking needle protector
US6428505B1 (en) 1999-11-19 2002-08-06 Prismedical Corporation In-line IV drug delivery pack with controllable dilution
DE19960226C1 (de) 1999-12-14 2001-05-10 Fresenius Ag Sterilitäterhaltendes Konnektionssystem für medizinische Systeme und dessen Verwendung
US7799009B2 (en) 2000-01-24 2010-09-21 Bracco Diagnostics Inc. Tabletop drug dispensing vial access adapter
US6139534A (en) 2000-01-24 2000-10-31 Bracco Diagnostics, Inc. Vial access adapter
US6832994B2 (en) 2000-01-24 2004-12-21 Bracco Diagnostics Inc. Table top drug dispensing vial access adapter
US6503240B1 (en) 2000-01-24 2003-01-07 Brocco Diagnostics, Inc. Vial access adapter
USD445501S1 (en) 2000-01-24 2001-07-24 Bracco Diagnostics, Inc. Vial access adapter
US6544246B1 (en) 2000-01-24 2003-04-08 Bracco Diagnostics, Inc. Vial access adapter and vial combination
US6706031B2 (en) 2000-02-15 2004-03-16 Comar, Inc. Needleless access apparatus and system
ES2223644T3 (es) 2000-02-16 2005-03-01 Haselmeier S.A R.L. Procedimiento de reconstitucion de un liquido de inyeccion, y aparato para llevar a cabo un procedimiento de este tipo.
US6530903B2 (en) 2000-02-24 2003-03-11 Xiping Wang Safety syringe
US6173868B1 (en) 2000-03-08 2001-01-16 Calmar Inc. Nasal sprayer with folding actuator
US6652509B1 (en) 2000-04-03 2003-11-25 Abbott Laboratories Housing capable of connecting a container to a medical device
JP4372310B2 (ja) 2000-04-10 2009-11-25 ニプロ株式会社 混注用アダプター
US6972002B2 (en) 2000-04-28 2005-12-06 Specialized Health Products, Inc. Passively activated safety shield for a catheter insertion needle
US6884253B1 (en) 2000-05-16 2005-04-26 Taut, Inc. Penetrating tip for trocar assembly
US6343629B1 (en) 2000-06-02 2002-02-05 Carmel Pharma Ab Coupling device for coupling a vial connector to a drug vial
WO2002000726A1 (en) * 2000-06-26 2002-01-03 Lumigen, Inc. Electrochemiluminescence from acridan compounds
US7530964B2 (en) 2000-06-30 2009-05-12 Elan Pharma International Limited Needle device and method thereof
US6499617B1 (en) 2000-07-17 2002-12-31 Brocco Diagnostics, Inc. Rotary seal stopper
JP2002035140A (ja) 2000-07-21 2002-02-05 Terumo Corp コネクタ
WO2002009797A1 (en) 2000-08-02 2002-02-07 Becton Dickinson And Company Pen needle and safety shield system
EP1324792A2 (en) 2000-09-21 2003-07-09 Elan Pharma International Limited Reconstitution and injection system
FR2815328B1 (fr) 2000-10-17 2002-12-20 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
JP2002191695A (ja) 2000-10-20 2002-07-09 Mitsubishi Pencil Co Ltd 針先カバー部材、針先カバー部材付き注射針の組立方法、針ガード部材付き注射針および針ガード部材付き注射器
US6769430B1 (en) 2000-10-31 2004-08-03 Kimberly-Clark Worldwide, Inc. Heat and moisture exchanger adaptor for closed suction catheter assembly and system containing the same
JP2002177392A (ja) 2000-11-08 2002-06-25 West Pharmaceutical Services Inc 注射器安全装置
FR2817566B1 (fr) 2000-12-04 2003-02-07 Freyssinet Int Stup Toron individuellement protege, son utilisation dans la construction, et procede de fabrication
US6666852B2 (en) 2000-12-04 2003-12-23 Bracco Diagnostics, Inc. Axially activated vial access adapter
US20020087118A1 (en) 2000-12-29 2002-07-04 Duoject Medical Systems Inc. Pharmaceutical delivery system
US6558365B2 (en) 2001-01-03 2003-05-06 Medimop Medical Projects, Ltd. Fluid transfer device
USD468015S1 (en) 2001-01-22 2002-12-31 Astra Tech Ab Combined connector with valve and non-return valve for medical equipment
US6474375B2 (en) 2001-02-02 2002-11-05 Baxter International Inc. Reconstitution device and method of use
WO2002066100A2 (en) 2001-02-20 2002-08-29 Medrad, Inc. Syringes, connectors, and syringe and connector systems for use in fluid delivery systems
US6503244B2 (en) 2001-03-07 2003-01-07 Micro Therapeutics, Inc. High pressure injection system
US6656433B2 (en) * 2001-03-07 2003-12-02 Churchill Medical Systems, Inc. Vial access device for use with various size drug vials
US6685692B2 (en) 2001-03-08 2004-02-03 Abbott Laboratories Drug delivery system
US20020138045A1 (en) 2001-03-20 2002-09-26 Moen Michael E. Quick connect fitting
WO2002076374A1 (en) 2001-03-27 2002-10-03 Eli Lilly And Company Kit including side firing syringe needle for preparing a drug in an injection pen cartridge
US6581593B1 (en) 2001-04-03 2003-06-24 Darren A. Rubin Universal oxygen connector system
US20030028156A1 (en) 2001-05-07 2003-02-06 Nexell Therapeutics, Inc. Fluid connector devices and methods of use
JP2002355318A (ja) 2001-06-01 2002-12-10 Terumo Corp 弁体付コネクター
EP1264609B1 (en) 2001-06-06 2006-01-18 Graziano Azzolini High-sterility and high-capacity connector for lines for outflow from bottles
USD457954S1 (en) 2001-06-19 2002-05-28 Becton, Dickinson And Company Syringe tip cap
JP2003033441A (ja) 2001-07-23 2003-02-04 Terumo Corp 三方活栓
US6453949B1 (en) 2001-08-08 2002-09-24 Sam Chau Plug for medical bayonet connectors and drug infusion ports
US6745998B2 (en) 2001-08-10 2004-06-08 Alaris Medical Systems, Inc. Valved male luer
USD476731S1 (en) 2001-08-27 2003-07-01 Kimberly-Clark Worldwide, Inc. Bendable connector
DE10142450C1 (de) 2001-08-31 2003-06-18 Aventis Behring Gmbh Vorrichtung zum Zusammenführen von Komponenten unter sterilen Bedingungen
FR2829691B1 (fr) 2001-09-17 2004-07-09 Sedat Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une carpule
US7354422B2 (en) 2001-09-26 2008-04-08 B. Braun Melsungen Ag Spring launched needle safety clip
JP4817564B2 (ja) 2001-09-28 2011-11-16 株式会社細川洋行 ニードルケース及び輸液容器
DE10149251B4 (de) 2001-10-05 2007-04-19 Sartorius Ag Vorrichtung zur genetischen Immunisierung durch Einbringen von Wirkstoffen in ein Gewebe und Verfahren zur Herstellung einer Injektionslösung
US20030069550A1 (en) 2001-10-06 2003-04-10 Sharp M. Keith Hypodermic needle
US6715520B2 (en) 2001-10-11 2004-04-06 Carmel Pharma Ab Method and assembly for fluid transfer
US20030073971A1 (en) 2001-10-17 2003-04-17 Saker Gordon Mark Universal connector and method for securing flexible tube assemblies
CA2467066C (en) 2001-11-14 2008-08-12 Jms Co., Ltd. Three-way stopcock, and liquid transfusion tubing set or blood transfusion tubing set using the three-way stopcock
US6802828B2 (en) 2001-11-23 2004-10-12 Duoject Medical Systems, Inc. System for filling and assembling pharmaceutical delivery devices
US6802490B2 (en) 2001-11-29 2004-10-12 Alaris Medical Systems, Inc. Needle free medical connector with expanded valve mechanism and method of fluid flow control
ATE316395T1 (de) 2001-11-30 2006-02-15 Novo Nordisk As Nadelsicherheitsvorrichtung
JP4451661B2 (ja) 2001-12-13 2010-04-14 ベクトン・ディキンソン・アンド・カンパニー 注射針閉鎖システム除去装置
EP1323403B1 (en) 2001-12-17 2006-04-19 Bristol-Myers Squibb Company Transfer device and system comprising a cap assembly, a container and the transfer device
US6651956B2 (en) 2002-01-31 2003-11-25 Halkey-Roberts Corporation Slit-type swabable valve
US6875205B2 (en) * 2002-02-08 2005-04-05 Alaris Medical Systems, Inc. Vial adapter having a needle-free valve for use with vial closures of different sizes
FR2836129B1 (fr) 2002-02-20 2004-04-02 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
AU2003201335B2 (en) 2002-03-20 2009-07-23 Becton, Dickinson And Company Shieldable needle assembly with biased safety shield
US8562583B2 (en) 2002-03-26 2013-10-22 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US9440046B2 (en) 2002-04-04 2016-09-13 Angiodynamics, Inc. Venous insufficiency treatment method
US7744581B2 (en) 2002-04-08 2010-06-29 Carmel Pharma Ab Device and method for mixing medical fluids
US7867215B2 (en) 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
US6740277B2 (en) 2002-04-24 2004-05-25 Becton Dickinson And Company Process of making a catheter
USD472630S1 (en) 2002-04-30 2003-04-01 Sterling Medivations, Inc. Pen needle catheter connector
USD472316S1 (en) 2002-04-30 2003-03-25 Sterling Medivations, Inc. Pen needle catheter connector
US6914212B2 (en) 2002-05-01 2005-07-05 Becton Dickinson And Company Method of making a needle and a needle
USD476733S1 (en) 2002-05-09 2003-07-01 Becton, Dickinson And Company Medical needle assembly
CN100482288C (zh) 2002-05-16 2009-04-29 斯科特实验室公司 药物容器进入机构和方法
US20030236543A1 (en) 2002-06-25 2003-12-25 Brenneman Allen J. Polygonal cross section lancet needle
JP4427965B2 (ja) 2002-07-02 2010-03-10 ニプロ株式会社 連通手段付き薬液容器
SE523001C2 (sv) 2002-07-09 2004-03-23 Carmel Pharma Ab En kopplingsdel, en koppling, en infusionspåse, en infusionsanordning och ett förfarande för överföring av medicinska substanser
US20040010207A1 (en) 2002-07-15 2004-01-15 Flaherty J. Christopher Self-contained, automatic transcutaneous physiologic sensing system
JP4209642B2 (ja) 2002-07-26 2009-01-14 川澄化学工業株式会社 針カバー及びキャップ付針カバー並びに針カバー付翼付針
US7326188B1 (en) 2002-08-02 2008-02-05 Elcam Medical Anesthesia manifold and induction valve
US7083600B2 (en) 2002-08-08 2006-08-01 Advanced Medical Sharps, Inc. Safety needle and shield
JP2004097253A (ja) 2002-09-04 2004-04-02 Nipro Corp 液体移注具
USD482447S1 (en) 2002-09-17 2003-11-18 Becton Dickinson And Company Needleless luer access port
USD482121S1 (en) 2002-09-17 2003-11-11 Becton Dickinson And Company Needleless luer access port
US6979318B1 (en) 2002-10-07 2005-12-27 Lemaitre Vascular, Inc. Catheter introducer
US20040073189A1 (en) 2002-10-09 2004-04-15 Phil Wyatt Vial access transfer set
US7544191B2 (en) 2002-10-22 2009-06-09 Baxter International Inc. Formed, filled, sealed solution container, port and method for establishing flow between the container and an administration set
USD483869S1 (en) 2002-10-29 2003-12-16 Pre Holding, Inc. Tubing connector
WO2004041148A1 (en) 2002-11-08 2004-05-21 Duoject Medical Systems Inc. Pharmaceutical delivery systems and methods for using same
US8100879B2 (en) 2002-11-18 2012-01-24 Nestec S.A. Connector device for enteral administration set
CH696186A5 (de) 2002-11-25 2007-02-15 Tecpharma Licensing Ag Vorrichtung zur Sicherung von Injektionsnadeln.
CA103134S (en) 2002-11-26 2004-08-11 Nipro Corp Adapter for transfer of medical solution
US7086431B2 (en) 2002-12-09 2006-08-08 D'antonio Consultants International, Inc. Injection cartridge filling apparatus
USD483487S1 (en) 2002-12-19 2003-12-09 Becton Dickinson And Company Stopcock device
JP4341239B2 (ja) 2002-12-19 2009-10-07 ニプロ株式会社 液体移注具
US7125396B2 (en) 2002-12-30 2006-10-24 Cardinal Health 303, Inc. Safety catheter system and method
US7140592B2 (en) 2002-12-31 2006-11-28 Cardinal Health 303, Inc. Self-sealing male Luer connector with biased valve plug
US20040143226A1 (en) 2003-01-16 2004-07-22 Becton, Dickinson And Company Blood collection set with venting mechanism
US20040143218A1 (en) 2003-01-21 2004-07-22 Animas Corporation Needle having optimum grind for reduced insertion force
US7678333B2 (en) 2003-01-22 2010-03-16 Duoject Medical Systems Inc. Fluid transfer assembly for pharmaceutical delivery system and method for using same
US7229419B2 (en) 2003-02-11 2007-06-12 Promex/U.S. Biosy Llc Single-handed biopsy system
US20040162540A1 (en) 2003-02-13 2004-08-19 Becton, Dickinson And Company Transfer device
DK1454609T3 (da) 2003-03-05 2013-02-11 Csl Behring Gmbh Overføringsindretning
ATE375181T1 (de) 2003-03-06 2007-10-15 Csl Behring Gmbh Transfervorrichtung, insbesondere für medizinische fluids
US20040181192A1 (en) 2003-03-11 2004-09-16 Cuppy Michael John Vascular access device and method of using same
US7470262B2 (en) 2003-03-17 2008-12-30 Nipro Corporation Medical valve
US7470265B2 (en) 2003-03-20 2008-12-30 Nxstage Medical, Inc. Dual access spike for infusate bags
US7024968B2 (en) 2003-03-26 2006-04-11 Boston Scientific Scimed, Inc. Luer lock wrench
US7001369B2 (en) 2003-03-27 2006-02-21 Scimed Life Systems, Inc. Medical device
US7040598B2 (en) 2003-05-14 2006-05-09 Cardinal Health 303, Inc. Self-sealing male connector
USD495416S1 (en) 2003-05-30 2004-08-31 Alaris Medical Systems, Inc. Vial access device
US20040249235A1 (en) 2003-06-03 2004-12-09 Connell Edward G. Hazardous material handling system and method
US6948522B2 (en) 2003-06-06 2005-09-27 Baxter International Inc. Reconstitution device and method of use
WO2004112866A2 (en) 2003-06-17 2004-12-29 Filtertek Inc. Fluid handling device and method of making same
FR2856660A1 (fr) 2003-06-30 2004-12-31 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
ITMO20030204A1 (it) 2003-07-14 2005-01-15 Gambro Lundia Ab Sacca per dialisi, set per dialisi comprendente detta
JP3883527B2 (ja) 2003-07-17 2007-02-21 ニプロ株式会社 トランスファーニードル
US7488297B2 (en) 2003-07-30 2009-02-10 Patrice Flaherty Blood collecting devices
US6960164B2 (en) 2003-08-01 2005-11-01 Neosurg Technologies, Inc. Obturator tip for a trocar
ES2798078T3 (es) 2003-08-12 2020-12-09 Becton Dickinson Co Dispositivo de infusión a modo de parche
CN1863566B (zh) 2003-08-12 2010-09-01 贝克顿·迪金森公司 片状输液装置
FR2858931B1 (fr) 2003-08-21 2007-04-13 Becton Dickinson France Dispositif d'administration orale d'un medicament
US7097637B2 (en) 2003-08-27 2006-08-29 C. R. Bard, Inc. Safety needle with positive flush
US20050082828A1 (en) 2003-09-12 2005-04-21 Wicks Jeffrey C. Releasable connection assembly for joining tubing sections
EP1687203A4 (en) 2003-10-30 2009-02-25 Teva Medical Ltd SAFETY DRUGS HANDLING DEVICE
FR2863161B1 (fr) 2003-12-05 2006-09-01 Map France Capuchon pour conditionnement de securite pour flacon a usage medical
US7712637B2 (en) 2003-12-11 2010-05-11 Gregory Lambrecht Wine extraction and preservation device and method
US20080009822A1 (en) 2003-12-18 2008-01-10 Halkey-Roberts Corporation Needleless access vial
EP1699506A2 (en) 2003-12-18 2006-09-13 Halkey-Roberts Corporation Needleless access vial
US20050137523A1 (en) 2003-12-22 2005-06-23 Wyatt Philip W. Medicament administration apparatus
US8454573B2 (en) 2008-05-06 2013-06-04 Philip Wyatt Medicament administration apparatus
US6997916B2 (en) 2004-01-02 2006-02-14 Smiths Medical Asd, Inc. Fluid transfer holder assembly and a method of fluid transfer
US6994315B2 (en) 2004-01-13 2006-02-07 Rymed Technologies, Inc. Swabbable needle-free injection port valve system with neutral fluid displacement
US7530546B2 (en) 2004-01-13 2009-05-12 Rymed Technologies, Inc. Swabbable needle-free injection port valve system with zero fluid displacement
US20050159706A1 (en) 2004-01-20 2005-07-21 Becton, Dickinson And Company Medical syringe with safety shield system
DE102004005435B3 (de) 2004-02-04 2005-09-15 Haindl, Hans, Dr. Medizinisches Transfergerät
IL160891A0 (en) 2004-03-16 2004-08-31 Auto-mix needle
US20050209554A1 (en) 2004-03-19 2005-09-22 Sergio Landau Needle-free single-use cartridge and injection system
WO2005097253A1 (en) 2004-03-26 2005-10-20 Cook Incorporated Method and apparatus for an improved luer fitting connection
DE102004021670A1 (de) 2004-05-03 2005-12-01 Saint-Gobain Calmar Gmbh Manuell betätigbarer Spender mit Schutzkappe
FR2869795B1 (fr) 2004-05-07 2006-08-04 Sedat Sa Dispositif de transfert bidirectionnel
US20050261637A1 (en) 2004-05-21 2005-11-24 Halkey-Roberts Corporation T-port with swabbable valve
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
DE102004036051A1 (de) 2004-07-24 2006-02-16 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Spritze
US7615041B2 (en) 2004-07-29 2009-11-10 Boston Scientific Scimed, Inc. Vial adaptor
DE202004012714U1 (de) 2004-08-12 2004-11-04 Smiths Medical Deutschland Gmbh Luer-Lock-Verbinder für medizinische Geräte
DE102004039408A1 (de) 2004-08-13 2006-03-02 Disetronic Licensing Ag Insertionskopf für medizinische oder pharmazeutische Anwendungen
JP2006061421A (ja) 2004-08-26 2006-03-09 Bio Media Co Ltd 薬剤収容ユニット
US20060161192A1 (en) 2004-09-03 2006-07-20 Young Christopher S Wound needle with composite cutting edge
JP5015778B2 (ja) 2004-09-03 2012-08-29 エルカム メディカル アグリカルチュラル コーポレイティブ アソシエイション リミティド 活栓
US20060106832A1 (en) 2004-10-04 2006-05-18 Ben-Dyke Andy D Method and system for implementing an enhanced database
US7731678B2 (en) 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
JP4821947B2 (ja) 2004-10-19 2011-11-24 朝日インテック株式会社 薬液注入装置
US7771383B2 (en) 2004-10-22 2010-08-10 Medegen, Inc. Fluid control device with valve and methods of use
US20060089594A1 (en) 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device
US7192423B2 (en) 2004-11-17 2007-03-20 Cindy Wong Dispensing spike assembly with removable indicia bands
US8826988B2 (en) 2004-11-23 2014-09-09 Weatherford/Lamb, Inc. Latch position indicator system and method
US7241285B1 (en) 2004-12-06 2007-07-10 Medical Ventures, Inc. Medical site connection
FR2878737B1 (fr) 2004-12-07 2007-03-16 Maptech Soc Par Actions Simpli Dispositif de securite pour flacon a usage medical
US7645274B2 (en) 2004-12-10 2010-01-12 Cardinal Health 303, Inc. Self-sealing male luer connector with multiple seats
US7523967B2 (en) 2004-12-13 2009-04-28 Alcon, Inc. Tubing fitting
US20060135948A1 (en) 2004-12-16 2006-06-22 Medtronic Vascular, Inc., A Delaware Corporation Multi-exchange catheter guide member with improved seal
US7935070B2 (en) 2005-01-28 2011-05-03 Fresenius Medical Care North America Systems and methods for dextrose containing peritoneal dialysis (PD) solutions with neutral pH and reduced glucose degradation product
US7704229B2 (en) 2005-02-03 2010-04-27 Medtronic Minimed, Inc. Insertion device
US7651482B2 (en) 2005-02-04 2010-01-26 Boston Scientific Scimed, Inc. Non-coring needles and methods of manufacturing same
ATE483442T1 (de) 2005-02-14 2010-10-15 Medimop Medical Projects Ltd Medizinische vorrichtung für die rekonstitution eines flüssigen arzneimittels in situ in medizinischen gefässen
US20090076360A1 (en) 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US20070060904A1 (en) 2005-03-14 2007-03-15 Becton, Dickinson And Company Filling system and method for syringes with short needles
US7666172B2 (en) 2005-03-15 2010-02-23 Plaridel Cerna Atil Medical needle having a closed tip
US20060253084A1 (en) 2005-05-03 2006-11-09 Greg Nordgren Outdwelling slit valves and assemblies for medical liquid flow through a cannula and related methods
WO2006124756A2 (en) 2005-05-13 2006-11-23 Bob Rogers Medical substance transfer system
CA111438S (fr) 2005-05-23 2006-12-22 Rexam Dispensing Sys Pulvérisateur nasal
US20070088292A1 (en) 2005-07-06 2007-04-19 Fangrow Thomas F Jr Medical connector with closeable male luer
JP2007024928A (ja) 2005-07-12 2007-02-01 Nidec Sankyo Corp 光ビーム出射装置および画像形成装置
US20080249479A1 (en) 2005-08-01 2008-10-09 Medimop Medical Projects Ltd. Liquid Drug Delivery System
EP1919432B1 (en) 2005-08-11 2011-10-19 Medimop Medical Projects Ltd. Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials
DK1764125T5 (da) 2005-09-15 2011-11-14 Hoffmann La Roche System bestående af indsættelseshoved og indsættelsesapparat
DE502005009907D1 (de) 2005-09-15 2010-08-26 Roche Diagnostics Gmbh Insertionskopf mit Griff
US8409142B2 (en) 2005-09-26 2013-04-02 Asante Solutions, Inc. Operating an infusion pump system
CA2625359A1 (en) 2005-10-11 2007-04-19 Blake Podaima Smart medical compliance method and system
WO2007053799A2 (en) 2005-10-19 2007-05-10 Cd Solutions, Llc Apparatus and method for mixing and transferring medications
US7611502B2 (en) 2005-10-20 2009-11-03 Covidien Ag Connector for enteral fluid delivery set
EP1957028B1 (en) 2005-10-30 2017-06-07 Medimop Medical Projects Ltd. Needleless additive control valve
ES2496968T3 (es) 2005-11-07 2014-09-22 Industrie Borla Spa Adaptador para frascos de manejo seguro de descarga
US7935104B2 (en) 2005-11-07 2011-05-03 Medingo, Ltd. Systems and methods for sustained medical infusion and devices related thereto
DE102005055326A1 (de) 2005-11-11 2007-05-16 Storz Karl Gmbh & Co Kg Anschluss für ein medizinisches Saug- oder Spülinstrument
GB0523638D0 (en) 2005-11-21 2005-12-28 Cambridge Biostability Ltd Pharmaceutical device for the administration of substances to patients
JP2007143813A (ja) 2005-11-28 2007-06-14 Nippon Sherwood Medical Industries Ltd 医療用活栓
US20070191767A1 (en) 2005-12-16 2007-08-16 Medtronic Vascular, Inc. Bifurcated Catheter Joints
US7981101B2 (en) 2005-12-30 2011-07-19 Carefusion 303, Inc. Medical vial adapter with reduced diameter cannula and enlarged vent lumen
DE502006005333D1 (de) 2006-02-16 2009-12-24 Roche Diagnostics Gmbh System und Vorrichtung zum Entnehmen von Pharmazeutika
JP2007222472A (ja) 2006-02-24 2007-09-06 Nipro Corp 薬剤微量投与具セット
WO2007101772A1 (en) 2006-03-07 2007-09-13 Novo Nordisk A/S A drug mixing device
EP1911432A1 (en) 2006-10-10 2008-04-16 Novo Nordisk A/S A mixing unit
WO2007102842A2 (en) 2006-03-09 2007-09-13 Dexcom, Inc. Systems and methods for processing analyte sensor data
IL174352A0 (en) 2006-03-16 2006-08-20 Medimop Medical Projects Ltd Medical devices for use with carpules
JP4769103B2 (ja) 2006-03-17 2011-09-07 日本シャーウッド株式会社 コネクタ
FR2898812B1 (fr) 2006-03-24 2008-06-13 Technoflex Sa Connecteur luer, connecteur medical et set de transfert comportant un tel connecteur
US8162904B2 (en) 2006-03-29 2012-04-24 Terumo Kabushiki Kaisha Needle protector
JP4775638B2 (ja) 2006-03-31 2011-09-21 株式会社ジェイ・エム・エス 連通部材、およびそれを用いた医療用容器、並びに輸液調剤用具セット
US7547300B2 (en) 2006-04-12 2009-06-16 Icu Medical, Inc. Vial adaptor for regulating pressure
WO2007118372A1 (fr) 2006-04-18 2007-10-25 Zhongshan Botai Pharmaceutic Instruments Co., Ltd. Seringue stérilisée servant au mélange de médicaments
JP4820703B2 (ja) 2006-04-28 2011-11-24 日本シャーウッド株式会社 液体混注具
US7731735B2 (en) 2006-04-28 2010-06-08 Warsaw Orthopedic, Inc. Open axle surgical implant
JP4871019B2 (ja) 2006-05-15 2012-02-08 日本コヴィディエン株式会社 液体混注具
CA2834152C (en) 2006-05-25 2016-07-05 Bayer Healthcare Llc Reconstitution device
CA2653129A1 (en) 2006-06-02 2007-12-13 Asahi Polyslider Company, Limited Pricking needle and lancet having the same
US8211082B2 (en) 2006-06-19 2012-07-03 Nipro Corporation Drug solution preparing kit
JP2008005974A (ja) 2006-06-28 2008-01-17 Nippon Sherwood Medical Industries Ltd ルアー固定フィッティング接続構造
EP2043585B1 (en) 2006-07-21 2010-04-28 Polimoon Medical Packaging A/S Connector device and method for sterile mixing
USD561348S1 (en) 2006-08-17 2008-02-05 Medimop Medical Projects Ltd. Vial adapter
US7670326B2 (en) 2006-09-25 2010-03-02 Teva Medical Ltd.. Syringe adapter element in drug mixing system
DE102006049528A1 (de) 2006-09-28 2008-04-03 Robert Bosch Gmbh Vorrichtung und Verfahren zur Montage eines Nadelschutzes auf einen Spritzenkörper
USD580558S1 (en) 2006-09-29 2008-11-11 Fujifilm Corporation Cap of cartridge for component extraction
US8167863B2 (en) 2006-10-16 2012-05-01 Carefusion 303, Inc. Vented vial adapter with filter for aerosol retention
JP5015258B2 (ja) 2006-10-25 2012-08-29 アイシーユー・メディカル・インコーポレーテッド 医療用コネクタ
EP2101711A1 (en) 2006-11-30 2009-09-23 Medi-Physics, Inc. Dual-lumen needle with an elongate notch opening
EP2121079A1 (en) 2006-11-30 2009-11-25 Medi-Physics, Inc. Dual-lumen needle
US7758082B2 (en) 2006-12-05 2010-07-20 Nxstage Medical, Inc. Fluid line connector safety device
US20080135051A1 (en) 2006-12-07 2008-06-12 George Lee Air Line Adapter Structure Of Suction Apparatus
US8002756B2 (en) 2006-12-08 2011-08-23 Becton, Dickinson And Company Method and apparatus for delivering a therapeutic substance through an injection port
US7900659B2 (en) 2006-12-19 2011-03-08 Carefusion 303, Inc. Pressure equalizing device for vial access
CN101610803A (zh) 2006-12-21 2009-12-23 Ssb技术有限公司 针尖
US8057431B2 (en) 2006-12-21 2011-11-15 B. Braun Melsungen Ag Hinged cap for needle device
IL180565A0 (en) 2007-01-04 2007-06-03 Ilan Brand An improved stopcock for administering medicaments into the patient's body
US8523830B2 (en) 2007-01-16 2013-09-03 Catheter Connections Disinfecting caps for medical female luer connectors
GB2446778A (en) 2007-02-01 2008-08-27 Pa Knowledge Ltd Syringe adaptor
US8038654B2 (en) 2007-02-26 2011-10-18 Becton, Dickinson And Company Syringe having a hinged needle shield
US7883499B2 (en) 2007-03-09 2011-02-08 Icu Medical, Inc. Vial adaptors and vials for regulating pressure
ATE477011T1 (de) 2007-03-14 2010-08-15 Hoffmann La Roche Insertionsvorrichtung für einen insertionskopf, insbesondere für ein infusionsset
GB0705782D0 (en) 2007-03-26 2007-05-02 Novartis Ag Vial assemblies
IL182605A0 (en) 2007-04-17 2007-07-24 Medimop Medical Projects Ltd Fluid control device with manually depressed actuator
JP5213950B2 (ja) 2007-04-23 2013-06-19 エス・アイ・ディ・テクノロジーズ・リミテッド・ライアビリティ・カンパニー 皮内注射のための方法および装置
CN102784058B (zh) 2007-04-23 2014-12-17 普拉斯特米德有限公司 用于无污染地传送危险药物的方法和设备
US8323250B2 (en) 2007-04-30 2012-12-04 Medtronic Minimed, Inc. Adhesive patch systems and methods
IL182922A0 (en) 2007-05-02 2007-09-20 Medimop Medical Projects Ltd Automatic liquid drug reconstitution apparatus
US20080306439A1 (en) 2007-06-08 2008-12-11 Nelson M Bud Devices for mixing and applying a fluid composition
USD588693S1 (en) 2007-06-12 2009-03-17 Nordson Corporation Liquid dispensing syringe
US8657803B2 (en) 2007-06-13 2014-02-25 Carmel Pharma Ab Device for providing fluid to a receptacle
US8801689B2 (en) 2007-08-01 2014-08-12 Hospira, Inc. Medicament admixing system
GB0716159D0 (en) 2007-08-17 2007-09-26 Precisense As Injection apparatus
US8475404B2 (en) 2007-08-21 2013-07-02 Yukon Medical, Llc Vial access and injection system
US9968742B2 (en) 2007-08-29 2018-05-15 Medtronic Minimed, Inc. Combined sensor and infusion set using separated sites
ES2542039T3 (es) 2007-08-30 2015-07-29 Carmel Pharma Ab Dispositivo, elemento de sellado y recipiente para fluidos
US8287513B2 (en) 2007-09-11 2012-10-16 Carmel Pharma Ab Piercing member protection device
EP2334357A4 (en) 2007-09-18 2011-08-31 Sabiedriba Ar Ierobezotu Atbildibu Sdmd SAFETY NEEDLE DEVICE
WO2009038860A2 (en) 2007-09-18 2009-03-26 Medeq Llc Medicament mixing and injection apparatus
IL186290A0 (en) 2007-09-25 2008-01-20 Medimop Medical Projects Ltd Liquid drug delivery devices for use with syringe having widened distal tip
DE102007046951B3 (de) 2007-10-01 2009-02-26 B. Braun Melsungen Ag Vorrichtung zum Einführen eines Medikaments in einen Infusionsbehälter
USD616090S1 (en) 2007-10-29 2010-05-18 Daikyo Seiko, Ltd. Sealing device for medicine container or medical apparatus
WO2009060419A2 (en) * 2007-11-08 2009-05-14 Elcam Medical A.C.A..L. Ltd Vial adaptor and manufacturing method therfor
DE102007061346A1 (de) 2007-12-17 2009-06-18 Bayer Schering Pharma Aktiengesellschaft Spike mit zwei Dornen
US9039673B2 (en) 2008-01-09 2015-05-26 Novartis Ag Unitary withdrawal spike unit suitable for factory fitting
US8287496B2 (en) 2008-01-17 2012-10-16 Custom Medical Applications, Inc. Flow elements for use with flexible spinal needles, needle assemblies and methods therefor
IL188975A0 (en) 2008-01-23 2008-11-03 Medimop Medical Projects Ltd Fluid control device with stopper
FR2927533B1 (fr) 2008-02-18 2011-02-11 P2A Medical Capuchon de transfert securise
DK2254542T3 (da) * 2008-02-18 2012-10-15 Icu Medical Inc Flaskeadapter
DE102008002800A1 (de) 2008-03-10 2009-09-24 Süddeutsche Feinmechanik GmbH Mischvorrichtung
WO2009146088A1 (en) 2008-04-01 2009-12-03 Yukon Medical, Llc Dual container fluid transfer device
US20090267011A1 (en) 2008-04-23 2009-10-29 Jason Hatton Dispensing valve assembly
FR2931363B1 (fr) 2008-05-23 2010-06-25 Vygon Connecteur pour circuit de liquide, notamment a usage medical et utilisation d'un tel connecteur
US8075550B2 (en) 2008-07-01 2011-12-13 Carmel Pharma Ab Piercing member protection device
US7967785B2 (en) 2008-07-14 2011-06-28 Nipro Healthcare Systems, Llc Insulin reservoir detection via magnetic switching
USD595862S1 (en) 2008-07-18 2009-07-07 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595420S1 (en) 2008-07-18 2009-06-30 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595421S1 (en) 2008-07-18 2009-06-30 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595863S1 (en) 2008-07-18 2009-07-07 Hitachi High-Technologies Corporation Adapter for a sample rack
GB0814747D0 (en) 2008-08-13 2008-09-17 Owen Mumford Ltd Autoinjection devices
US8551068B2 (en) 2008-08-22 2013-10-08 Circle Biologics, Inc. Fluid management devices and methods
US8480645B1 (en) 2008-08-22 2013-07-09 Sambhu N. Choudhury Multi-dose device for insertion into a vial and method of using the same
JP5854836B2 (ja) 2008-08-30 2016-02-09 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング カートリッジ及びそのための針システム
US8523837B2 (en) 2008-10-14 2013-09-03 Mead Johnson Nutrition Company Nutritive substance delivery container
US7762524B2 (en) 2008-10-20 2010-07-27 Baxter International Inc. Barrier assembly for use with needleless connector
WO2010054463A1 (en) 2008-11-12 2010-05-20 British Columbia Cancer Agency Branch Vial handling and injection safety systems and connectors
WO2010058806A1 (ja) 2008-11-21 2010-05-27 テルモ株式会社 接続具
CN102223866B (zh) 2008-11-25 2014-07-02 株式会社Jms 连接器
WO2010061742A1 (ja) 2008-11-25 2010-06-03 株式会社ジェイ・エム・エス コネクタ
US9370621B2 (en) 2008-12-16 2016-06-21 Medtronic Minimed, Inc. Needle insertion systems and methods
US20100160889A1 (en) 2008-12-22 2010-06-24 Baxter International Inc. Vial access spike assembly
EP2201968A1 (de) 2008-12-24 2010-06-30 Roche Diagnostics GmbH Insertionssystem und Insertionsvorrichtung
US8152779B2 (en) 2008-12-30 2012-04-10 Medimop Medical Projects Ltd. Needle assembly for drug pump
US8512309B2 (en) 2009-01-15 2013-08-20 Teva Medical Ltd. Vial adapter element
US8221352B2 (en) 2009-01-29 2012-07-17 Michael Merchant Disposable safety needle system and safety enclosure means
WO2010089310A1 (en) 2009-02-05 2010-08-12 Sanofi-Aventis Deutschland Gmbh Medicament delivery devices
US8123736B2 (en) 2009-02-10 2012-02-28 Kraushaar Timothy Y Cap adapters for medicament vial and associated methods
US8012132B2 (en) 2009-02-24 2011-09-06 Becton, Dickinson And Company Luer-snap connection and luer-snap syringe
USD608900S1 (en) 2009-03-06 2010-01-26 Csp Technologies, Inc. Identification component for a vial
US8864725B2 (en) 2009-03-17 2014-10-21 Baxter Corporation Englewood Hazardous drug handling system, apparatus and method
USD634007S1 (en) 2009-03-31 2011-03-08 Medimop Medical Projects Ltd. Needleless additive control valve
USD641080S1 (en) 2009-03-31 2011-07-05 Medimop Medical Projects Ltd. Medical device having syringe port with locking mechanism
US8182452B2 (en) 2009-04-06 2012-05-22 Carefusion 303, Inc. Closed male luer device for use with needleless access devices
WO2010120953A2 (en) 2009-04-14 2010-10-21 Yukon Medical, Llc Fluid transfer device
US7963939B2 (en) 2009-04-24 2011-06-21 Thomas Chun Syringe having extended blending path
US8308741B2 (en) 2009-04-28 2012-11-13 The Invention Science Fund I, Llc Systems and methods for automatically inserting a needle into a living subject
WO2011002853A2 (en) 2009-07-01 2011-01-06 Fresenius Medical Care Holdings, Inc. Drug delivery devices and related systems and methods
DE202009011019U1 (de) 2009-07-01 2010-12-02 Süddeutsche Feinmechanik GmbH Anordnung zum Entnehmen eines Mediums aus einem Fläschchen
USD616984S1 (en) 2009-07-02 2010-06-01 Medimop Medical Projects Ltd. Vial adapter having side windows
IL199767A0 (en) 2009-07-09 2010-04-15 Medimop Medical Projects Ltd Medical device for use with cartridge and vial
JP5333850B2 (ja) 2009-07-15 2013-11-06 ニプロ株式会社 連結器具
USD655071S1 (en) 2009-07-17 2012-03-06 Julia Graciela Davila Mariachi suit
USD627216S1 (en) 2009-07-21 2010-11-16 The United States Of America As Represented By The Director, National Security Agency Tamper cup seal
IL200547A (en) 2009-08-23 2014-06-30 Eli Shemesh A system for mixing drugs in many containers
US9149624B2 (en) 2009-09-02 2015-10-06 Carefusion 303, Inc. Disinfecting male luer connector caps
USD630732S1 (en) 2009-09-29 2011-01-11 Medimop Medical Projects Ltd. Vial adapter with female connector
IL201323A0 (en) 2009-10-01 2010-05-31 Medimop Medical Projects Ltd Fluid transfer device for assembling a vial with pre-attached female connector
AU2010310457B2 (en) 2009-10-23 2015-07-02 Amgen Inc. Vial adapter and system
IL202069A0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Fluid transfer device with sealing arrangement
IL202070A0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Inline liquid drug medical device
USD637713S1 (en) 2009-11-20 2011-05-10 Carmel Pharma Ab Medical device adaptor
US8480646B2 (en) 2009-11-20 2013-07-09 Carmel Pharma Ab Medical device connector
JP5379314B2 (ja) 2009-12-23 2013-12-25 メディモップ・メディカル・プロジェクツ・リミテッド 液剤用量を復元し投与するための、医療用装置、および、この医療用装置とともに使用するための流れ制御デバイスを含む一回使い切りキット
US8998840B2 (en) 2009-12-30 2015-04-07 Medtronic Minimed, Inc. Connection and alignment systems and methods
MX2012008190A (es) 2010-01-15 2012-08-03 Bayer Healthcare Llc Dispositivo.
JP2013517081A (ja) 2010-01-19 2013-05-16 ケンブリッジ・エンタープライズ・リミテッド 装置及び方法
US8348898B2 (en) 2010-01-19 2013-01-08 Medimop Medical Projects Ltd. Automatic needle for drug pump
EP2361599A1 (de) 2010-02-22 2011-08-31 Fresenius Kabi Deutschland GmbH Vorrichtung zum Zuführen oder Entnehmen einer Flüssigkeit in ein oder aus einem Behältnis
US8753325B2 (en) 2010-02-24 2014-06-17 Medimop Medical Projects, Ltd. Liquid drug transfer device with vented vial adapter
EP2545950A4 (en) 2010-03-10 2014-05-07 Terumo Corp Injection needle assembly and drug injection device
US20130018326A1 (en) * 2010-04-01 2013-01-17 Enable Injections, Llc Medical fluid injection device and system
US9980707B2 (en) 2011-04-04 2018-05-29 Cook Medical Technologies Llc Endoscopic ultrasound-guided biopsy needle
USD644104S1 (en) 2010-04-15 2011-08-30 Sumitomo Rubber Industries, Ltd. Rubber stopper for vial
US8702674B2 (en) 2010-04-27 2014-04-22 Crisi Medical Systems, Inc. Medication and identification information transfer apparatus
EP2571549B1 (en) 2010-05-20 2016-02-24 Becton Dickinson and Company Drug delivery device
BR112012031121B1 (pt) 2010-06-07 2022-09-27 Amgen Inc Dispositivo de distribuição de drogas, kit e método de operar um dispositivo de distribuição de droga utilizável
USD655017S1 (en) 2010-06-17 2012-02-28 Yukon Medical, Llc Shroud
EP2589402B1 (en) 2010-06-30 2018-07-25 Nipro Corporation Spraying device
WO2012004784A1 (en) 2010-07-04 2012-01-12 Medimop Medical Projects Ltd Vial adapter with syringe stabilizer
US8721627B2 (en) 2010-07-22 2014-05-13 Carefusion 303, Inc. Needleless valve infection prevention and pre-opening device
USD654166S1 (en) 2010-08-06 2012-02-14 Neomed, Inc. Enteral connector
KR102253635B1 (ko) 2010-08-25 2021-05-20 박스앨타 게엠베하 사용자 재구성을 용이하게 하는 어셈블리
US20120078214A1 (en) 2010-09-28 2012-03-29 Tyco Healthcare Group Lp Vial transfer needle assembly
USD669980S1 (en) 2010-10-15 2012-10-30 Medimop Medical Projects Ltd. Vented vial adapter
IL209102A0 (en) 2010-11-04 2011-01-31 Medimop Medical Projects Ltd Inline liquid drug medical device with handle operated flow control member
IL209290A0 (en) 2010-11-14 2011-01-31 Medimop Medical Projects Ltd Inline liquid drug medical device having rotary flow control member
EP2462913A1 (en) 2010-12-10 2012-06-13 Fresenius Medical Care Deutschland GmbH Insert and vial for the infusion of liquids
WO2012110057A1 (en) * 2011-02-15 2012-08-23 Chemisches Institut Schaefer Ag Cefuroxime safety kit
JP5670242B2 (ja) 2011-03-29 2015-02-18 テルモ株式会社 薬剤調製用具
US20120265163A1 (en) 2011-04-14 2012-10-18 Marc Bunjiun Cheng Coupling system to transfer material between containers
IL212420A0 (en) 2011-04-17 2011-06-30 Medimop Medical Projects Ltd Liquid drug transfer assembly
USD720067S1 (en) 2011-05-02 2014-12-23 Carmel Pharma Ab Medical device
WO2012150587A1 (en) 2011-05-03 2012-11-08 Sabiedriba Ar Ierobezotu Atbildibu "Sdmd" Vial adaptor
FR2975896B1 (fr) 2011-06-06 2014-06-06 Biocorp Rech Et Dev Dispositif de connexion entre un recipient et un contenant, procede d'assemblage et d'utilisation d'un tel dispositif
WO2012174464A2 (en) 2011-06-17 2012-12-20 Tautona Group Lp Needle for delivery of dermal filler threads
USD673673S1 (en) 2011-07-11 2013-01-01 Hsien-Tsung Wang Transparent Y-type of intravenous drip infusion set
USD674084S1 (en) 2011-07-21 2013-01-08 Mtp Medical Technical Promotion Gmbh Puncture cannula
US20140194854A1 (en) 2011-08-29 2014-07-10 Sid Technologies Llc Subcutaneous and intradermal patch infusers
USD681230S1 (en) 2011-09-08 2013-04-30 Yukon Medical, Llc Shroud
IL215699A0 (en) 2011-10-11 2011-12-29 Medimop Medical Projects Ltd Liquid drug reconstitution assemblage for use with iv bag and drug vial
USD711516S1 (en) 2011-12-09 2014-08-19 John Guest International Limited Fluid connector
USD720452S1 (en) 2011-12-15 2014-12-30 Mark Jordan Syringe connection hub
AU344164S (en) 2012-02-02 2012-09-04 Terumo Corp Safety device for indwelling needle
USD720451S1 (en) 2012-02-13 2014-12-30 Medimop Medical Projects Ltd. Liquid drug transfer assembly
USD674088S1 (en) 2012-02-13 2013-01-08 Medimop Medical Projects Ltd. Vial adapter
US20150013835A1 (en) 2012-02-29 2015-01-15 Sanofi-Aventis Deutschland Gmbh Extraction device for a single extraction of a medicament from a container
US10206854B2 (en) 2012-03-05 2019-02-19 Becton, Dickinson And Company Transfer set with floating needle for drug reconstitution
US20130253448A1 (en) 2012-03-09 2013-09-26 Steven Baron Hypodermic Needle With Multiple Dispersement Openings
US9072827B2 (en) 2012-03-26 2015-07-07 Medimop Medical Projects Ltd. Fail safe point protector for needle safety flap
IL219065A0 (en) 2012-04-05 2012-07-31 Medimop Medical Projects Ltd Fluid transfer device with manual operated cartridge release arrangement
IL219222A0 (en) 2012-04-17 2012-07-31 Medimop Medical Projects Ltd Quick release vial adapter
ITRM20120169A1 (it) 2012-04-19 2013-10-20 Consiglio Nazionale Ricerche Dispositivo di rilascio di specie chimiche a controllo ottico
JP5888606B2 (ja) 2012-06-18 2016-03-22 ニプロ株式会社 薬剤調製器具
IL221635A0 (en) 2012-08-26 2012-12-31 Medimop Medical Projects Ltd Drug vial mixing and transfer device for use with iv bag and drug vial
US9339438B2 (en) * 2012-09-13 2016-05-17 Medimop Medical Projects Ltd. Telescopic female drug vial adapter
US20150290390A1 (en) 2012-11-21 2015-10-15 Amgen Inc. Drug delivery device
CN107929858B (zh) 2012-11-30 2021-03-12 贝克顿迪金森有限公司 用于药品输送组件的输注适配器
USD717406S1 (en) 2012-12-10 2014-11-11 Enviro Water Solutions, Inc. Backwash fitting
USD714935S1 (en) 2013-01-10 2014-10-07 Fuso Pharmaeutical Industries, Ltd. Adapter for connecting a needle to a syringe
USD733291S1 (en) 2013-01-15 2015-06-30 Hsien-Tsung Wang Depressible plug for vial
US9089475B2 (en) 2013-01-23 2015-07-28 Icu Medical, Inc. Pressure-regulating vial adaptors
USD732664S1 (en) 2013-02-25 2015-06-23 B. Braun Melsungen Ag Proximal catheter hub body
USD738494S1 (en) 2013-03-05 2015-09-08 Ikashmore Pty Ltd Blood collection safety device
USD733292S1 (en) 2013-03-10 2015-06-30 Rocomp Global, Llc Energy guide
US9308020B2 (en) 2013-03-14 2016-04-12 Cook Medical Technologies Llc Tri-fluted vascular access needle
USD720850S1 (en) 2013-03-15 2015-01-06 Sanovas, Inc. Catheter hub
USD733293S1 (en) 2013-03-15 2015-06-30 Rocomp Global, Llc Energy guide
GB201307385D0 (en) 2013-04-24 2013-06-05 Star Syringe Ltd Syringes
WO2015042517A2 (en) 2013-09-23 2015-03-26 Becton, Dickinson And Company, Ltd. Piercing member for container access device
AU353353S (en) 2013-10-02 2014-01-21 Terumo Corp Medical syringe
US10391031B2 (en) 2013-11-06 2019-08-27 Becton Diskinson and Company Limited Adapter for vial access device
US20150305770A1 (en) 2014-03-12 2015-10-29 Epicardial Frontiers, LLC System and method of image guided pericardial procedures including pericardioscopy, pericardial ablation, pericardial material delivery, pericardial tissue grasping and manipulation, pericardial lead placement, and pericardial surgical fastener placement
USD794183S1 (en) 2014-03-19 2017-08-08 Medimop Medical Projects Ltd. Dual ended liquid transfer spike
USD750235S1 (en) 2014-03-19 2016-02-23 ERBE-USA, Inc. Endoscope connector
CN107073211B (zh) 2014-08-14 2021-01-05 韦贝尔Cds公司 具有可选择的流动通道和密封部的注射器
USD757933S1 (en) 2014-09-11 2016-05-31 Medimop Medical Projects Ltd. Dual vial adapter assemblage
JP6368603B2 (ja) 2014-09-25 2018-08-01 テルモ株式会社 消毒キャップ
JP2018501037A (ja) 2015-01-09 2018-01-18 ベクトン ディキンソン アンド カンパニー リミテッド 注入アダプタ

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100560046C (zh) * 2004-04-29 2009-11-18 麦迪麦珀医疗工程有限公司 液体药物医疗装置
DE102005017985A1 (de) * 2005-04-19 2006-10-26 Theo Arnitz Verfahren und Vorrichtungen zum Auflösen von Medikamenten für Injektionen
CN102711712A (zh) * 2010-02-24 2012-10-03 麦迪麦珀医疗工程有限公司 具有通风布置的流体转移组合件
CN104755059A (zh) * 2012-08-26 2015-07-01 麦迪麦珀医疗工程有限公司 液体药物转移装置

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