CN106687079B - 眼睛植入输送装置和方法 - Google Patents
眼睛植入输送装置和方法 Download PDFInfo
- Publication number
- CN106687079B CN106687079B CN201580048475.0A CN201580048475A CN106687079B CN 106687079 B CN106687079 B CN 106687079B CN 201580048475 A CN201580048475 A CN 201580048475A CN 106687079 B CN106687079 B CN 106687079B
- Authority
- CN
- China
- Prior art keywords
- guide sleeve
- implantation material
- shell
- implant
- pair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000007943 implant Substances 0.000 title claims abstract description 294
- 238000000034 method Methods 0.000 title abstract description 12
- 239000000463 material Substances 0.000 claims description 59
- 238000002513 implantation Methods 0.000 claims description 58
- 239000003814 drug Substances 0.000 claims description 45
- 229940124597 therapeutic agent Drugs 0.000 claims description 27
- 229940079593 drug Drugs 0.000 claims description 18
- 238000005452 bending Methods 0.000 claims 2
- 238000000926 separation method Methods 0.000 claims 2
- 210000002105 tongue Anatomy 0.000 description 61
- 230000007246 mechanism Effects 0.000 description 24
- 230000014759 maintenance of location Effects 0.000 description 20
- 239000012530 fluid Substances 0.000 description 10
- 238000003780 insertion Methods 0.000 description 10
- 230000037431 insertion Effects 0.000 description 10
- 230000037452 priming Effects 0.000 description 8
- 238000012377 drug delivery Methods 0.000 description 6
- 238000009472 formulation Methods 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- 230000000717 retained effect Effects 0.000 description 4
- 210000003811 finger Anatomy 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 210000003813 thumb Anatomy 0.000 description 3
- 230000007704 transition Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000013265 extended release Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000002090 nanochannel Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Prostheses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462024682P | 2014-07-15 | 2014-07-15 | |
| US62/024,682 | 2014-07-15 | ||
| PCT/US2015/040633 WO2016011191A1 (en) | 2014-07-15 | 2015-07-15 | Ocular implant delivery device and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106687079A CN106687079A (zh) | 2017-05-17 |
| CN106687079B true CN106687079B (zh) | 2019-10-11 |
Family
ID=55079028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580048475.0A Active CN106687079B (zh) | 2014-07-15 | 2015-07-15 | 眼睛植入输送装置和方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US10258503B2 (enExample) |
| EP (2) | EP3679908B1 (enExample) |
| JP (1) | JP6581194B2 (enExample) |
| KR (1) | KR102416726B1 (enExample) |
| CN (1) | CN106687079B (enExample) |
| AU (1) | AU2015289625B2 (enExample) |
| BR (1) | BR112017000774B1 (enExample) |
| CA (1) | CA2955186C (enExample) |
| ES (2) | ES2803102T3 (enExample) |
| IL (1) | IL250079B (enExample) |
| MX (1) | MX384889B (enExample) |
| MY (1) | MY182497A (enExample) |
| RU (1) | RU2695563C2 (enExample) |
| WO (1) | WO2016011191A1 (enExample) |
| ZA (1) | ZA201700387B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3045436C (en) | 2009-01-29 | 2025-10-07 | Forsight Vision4 Inc | Posterior segment drug delivery |
| US10010448B2 (en) | 2012-02-03 | 2018-07-03 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| ES2972168T3 (es) | 2013-03-28 | 2024-06-11 | Forsight Vision4 Inc | Implante oftálmico para administración de sustancias terapéuticas |
| WO2016011191A1 (en) * | 2014-07-15 | 2016-01-21 | Forsight Vision4, Inc. | Ocular implant delivery device and method |
| JP2017522122A (ja) | 2014-07-24 | 2017-08-10 | シノプシス サージカル インコーポレイテッドＳｉｎｏｐｓｙｓ Ｓｕｒｇｉｃａｌ，Ｉｎｃ． | 副鼻腔アクセスインプラントデバイスおよび関連する製品ならびに方法 |
| CA2957548A1 (en) | 2014-08-08 | 2016-02-11 | Forsight Vision4, Inc. | Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof |
| BR112017009660A2 (pt) * | 2014-11-10 | 2017-12-19 | Forsight Vision4 Inc | dispositivos de administração de fármacos expansíveis e métodos de utilização |
| JP6912475B2 (ja) | 2015-11-20 | 2021-08-04 | フォーサイト・ビジョン フォー・インコーポレーテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ４， Ｉｎｃ． | 持続放出性薬物送達機器用の多孔質構造体 |
| AR108177A1 (es) | 2016-04-05 | 2018-07-25 | Forsight Vision4 Inc | Dispositivos de suministro de fármacos oculares implantables |
| FI3675780T3 (fi) * | 2017-09-20 | 2025-03-13 | Sinopsys Surgical Inc | Paranasaaliseen sinukseen nestepääsyn mahdollistavia implantointityökaluja ja -kokoonpanoja |
| CN115607358A (zh) | 2017-11-21 | 2023-01-17 | 弗赛特影像4股份有限公司 | 用于可扩展端口递送系统的流体交换装置及使用方法 |
| EP3698758A1 (en) * | 2019-02-20 | 2020-08-26 | Leibniz-Institut für Polymerforschung Dresden e.V. | Device and assemblies for oriented transport, microscopic investigation and oriented ejection of a tissue graft or implant |
| CN110507476B (zh) * | 2019-09-12 | 2021-10-26 | 格劳科斯公司 | 制造眼部植入物输送装置的方法 |
| CN115209835A (zh) * | 2020-02-27 | 2022-10-18 | 伊斯塔尔医疗公司 | 用于保持和分配用于输送植入物的输送轴组件的包装件 |
| RS65459B1 (sr) * | 2020-02-27 | 2024-05-31 | Istar Medical Sa | Pakovanje za držanje i dispenziju osovinskog sklopa za postavljanje implantata |
| US20220054311A1 (en) * | 2020-08-12 | 2022-02-24 | United States Government As Represented By The Department Of Veterans Affairs | Eye Drop Dispensing Apparatus |
| US12268633B2 (en) | 2020-11-04 | 2025-04-08 | Alcon Inc. | Medical implant |
| AU2022345173A1 (en) | 2021-09-20 | 2024-05-02 | Mott Corporation | Polymer coating for medical devices and method of manufacture |
| USD1037439S1 (en) | 2022-01-17 | 2024-07-30 | EyePoint Pharamaceuticals, Inc. | Ocular injector |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
| CN114848289B (zh) * | 2022-05-06 | 2025-02-14 | 海思盖德(苏州)生物医学科技有限公司 | 一种眼部植入物输送器 |
| CN114983670B (zh) * | 2022-05-30 | 2025-08-01 | 海思盖德(苏州)生物医学科技有限公司 | 一种眼内植入物输送器 |
| USD1101145S1 (en) | 2022-08-11 | 2025-11-04 | Genentech, Inc. | Ocular incision guide tool |
| CN118512302B (zh) * | 2024-07-23 | 2024-10-01 | 苏州朗目医疗科技有限公司 | 一种眼用缓释药输送系统 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102098993A (zh) * | 2008-04-25 | 2011-06-15 | 加利福尼亚大学董事会 | 储藏并注入角膜移植物的装置 |
| CN102365109A (zh) * | 2009-01-29 | 2012-02-29 | 弗赛特影像4股份有限公司 | 后段给药 |
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