MX2010004366A - Materiales inmiscibles en agua como vehiculos para suministro de farmacos. - Google Patents

Materiales inmiscibles en agua como vehiculos para suministro de farmacos.

Info

Publication number
MX2010004366A
MX2010004366A MX2010004366A MX2010004366A MX2010004366A MX 2010004366 A MX2010004366 A MX 2010004366A MX 2010004366 A MX2010004366 A MX 2010004366A MX 2010004366 A MX2010004366 A MX 2010004366A MX 2010004366 A MX2010004366 A MX 2010004366A
Authority
MX
Mexico
Prior art keywords
water
vehicles
drug delivery
immiscible materials
immiscible
Prior art date
Application number
MX2010004366A
Other languages
English (en)
Inventor
Brian R Rohrs
Martin J Coffey
Original Assignee
Bausch & Lomb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb filed Critical Bausch & Lomb
Publication of MX2010004366A publication Critical patent/MX2010004366A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Abstract

Se describe una composición farmacéutica que incluye al menos un componente farmacéutico y por lo menos un material inmiscible en agua. El componente farmacéutico es más soluble en el material inmiscible en agua que en agua. La composición farmacéutica es adecuada para administración ocular.
MX2010004366A 2007-11-05 2008-10-22 Materiales inmiscibles en agua como vehiculos para suministro de farmacos. MX2010004366A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98530807P 2007-11-05 2007-11-05
PCT/US2008/080665 WO2009061607A2 (en) 2007-11-05 2008-10-22 Water-immiscible materials as vehicles for drug delivery

Publications (1)

Publication Number Publication Date
MX2010004366A true MX2010004366A (es) 2010-05-05

Family

ID=40185076

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010004366A MX2010004366A (es) 2007-11-05 2008-10-22 Materiales inmiscibles en agua como vehiculos para suministro de farmacos.

Country Status (13)

Country Link
US (1) US20100286121A1 (es)
EP (1) EP2214644B1 (es)
JP (1) JP2011502990A (es)
KR (1) KR20100067684A (es)
CN (1) CN101848701A (es)
AU (1) AU2008325036B2 (es)
BR (1) BRPI0819175A2 (es)
CA (1) CA2703000C (es)
ES (1) ES2402321T3 (es)
HK (1) HK1144073A1 (es)
MX (1) MX2010004366A (es)
SG (1) SG185955A1 (es)
WO (1) WO2009061607A2 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2391419T3 (pl) 2009-01-29 2019-12-31 Forsight Vision4, Inc. Dostarczanie leku do tylnego odcinka
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
EP2394636B1 (en) * 2010-05-28 2014-03-19 Novagali Pharma S.A. Method for treating retinal conditions using an intraocular tamponade
US10166142B2 (en) 2010-01-29 2019-01-01 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
WO2012019136A2 (en) 2010-08-05 2012-02-09 Forsight Vision 4, Inc. Injector apparatus and method for drug delivery
CA2807537C (en) 2010-08-05 2018-09-18 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
EP3960134A1 (en) 2010-08-05 2022-03-02 ForSight Vision4, Inc. Implantable therapeutic device
CA2818612C (en) 2010-11-19 2020-12-29 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
EP2726016B1 (en) 2011-06-28 2023-07-19 ForSight Vision4, Inc. An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye
PT2755600T (pt) 2011-09-16 2021-04-19 Forsight Vision4 Inc Aparelhos de troca de fluidos
US10010448B2 (en) 2012-02-03 2018-07-03 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
US9056057B2 (en) 2012-05-03 2015-06-16 Kala Pharmaceuticals, Inc. Nanocrystals, compositions, and methods that aid particle transport in mucus
KR102154880B1 (ko) 2012-05-03 2020-09-10 칼라 파마슈티컬스, 인크. 개선된 점막 수송을 나타내는 제약 나노입자
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US9968603B2 (en) 2013-03-14 2018-05-15 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
US9526654B2 (en) 2013-03-28 2016-12-27 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
BR112016022394A2 (pt) * 2014-03-27 2017-08-15 Servicio Andaluz De Salud Composição farmaceuticamente aceitável, composição na forma de uma solução injetável farmaceuticamente aceitável, uso da composição, e, método para a preparação da composição injetável farmaceuticamente aceitável
EP3679908A1 (en) 2014-07-15 2020-07-15 ForSight Vision4, Inc. Ocular implant delivery device
CN107106551A (zh) 2014-08-08 2017-08-29 弗赛特影像4股份有限公司 受体酪氨酸激酶抑制剂的稳定且可溶的制剂和其制备方法
AU2015346450B2 (en) 2014-11-10 2020-01-30 Forsight Vision4, Inc. Expandable drug delivery devices and method of use
US11324800B2 (en) 2015-01-15 2022-05-10 Wellspring Ophthalmics, Inc. Aqueous suspensions of cyclosporin
US20200237859A1 (en) 2019-01-25 2020-07-30 Newport Research, Inc. Aqueous suspensions of cyclosporin
JP2018510872A (ja) * 2015-03-23 2018-04-19 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 高濃度かつ／または高粘度の活性薬剤溶液を注射するための方法および組成物
CN113069681B (zh) 2015-11-20 2022-12-23 弗赛特影像4股份有限公司 制造用于缓释药物递送的治疗装置的方法
US20170196802A1 (en) 2016-01-08 2017-07-13 Abon Pharmaceuticals, Llc Long Acting Injectable Formulations
MX2018012021A (es) 2016-04-05 2019-01-24 Forsight Vision4 Inc Dispositivos de administracion de farmacos oculares implantables.
PT3266446T (pt) * 2016-07-07 2019-01-30 Salvat Lab Sa Composição oftálmica compreendendo óleo de rícino e triglicérido de cadeia média
CN115607358A (zh) 2017-11-21 2023-01-17 弗赛特影像4股份有限公司 用于可扩展端口递送系统的流体交换装置及使用方法
MX2020011535A (es) * 2018-05-01 2020-11-24 Chibi Inc Formulacion de gotas para ojos y metodos para la liberacion sostenida de medicamento a la retina.
CN109091675B (zh) * 2018-08-31 2021-09-17 杭州赫尔斯科技有限公司 一种复方低浓度阿托品类药物滴眼液及其制备方法
CN113749092A (zh) * 2020-06-03 2021-12-07 迈克斯(如东)化工有限公司 不饱和脂肪酸酯化物应用、农化组合物和低眼刺农药制剂及其应用

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3767788A (en) * 1970-06-08 1973-10-23 Burton Parsons Chemicals Inc Ophthalmic solution
FR2638089A1 (fr) * 1988-10-26 1990-04-27 Sandoz Sa Nouvelles compositions ophtalmiques a base d'une cyclosporine
JP2613139B2 (ja) * 1990-07-19 1997-05-21 エスエス製薬 株式会社 キノロンカルボン酸誘導体
US5518731A (en) * 1990-09-27 1996-05-21 Allergan, Inc. Nonaqueous fluorinated drug delivery vehicle suspensions
US5912015A (en) * 1992-03-12 1999-06-15 Alkermes Controlled Therapeutics, Inc. Modulated release from biocompatible polymers
US5384333A (en) * 1992-03-17 1995-01-24 University Of Miami Biodegradable injectable drug delivery polymer
US5830508A (en) * 1992-08-06 1998-11-03 Deo Corporation Composition for treating dry eye
US5366739A (en) * 1992-08-06 1994-11-22 Deo Corporation Method of ophthalmic drug delivery
EP0656779B1 (en) * 1992-08-28 2000-04-12 Pharmos Corporation Submicron emulsions as ocular drug delivery vehicles
US5336487A (en) * 1993-03-05 1994-08-09 Refojo Miguel F Method of treating eye disorders with silicon/fluorosilicone copolymer oil
US5480914A (en) * 1994-05-06 1996-01-02 Allergan, Inc. Nonaqueous thixotropic drug delivery suspensions and methods of their use
US5718922A (en) * 1995-05-31 1998-02-17 Schepens Eye Research Institute, Inc. Intravitreal microsphere drug delivery and method of preparation
US5736152A (en) * 1995-10-27 1998-04-07 Atrix Laboratories, Inc. Non-polymeric sustained release delivery system
US6331311B1 (en) * 1996-12-20 2001-12-18 Alza Corporation Injectable depot gel composition and method of preparing the composition
EP1082966A4 (en) * 1998-05-15 2004-07-21 Wakamoto Pharma Co Ltd ANTI-INFLAMMATORY EYE DROPS
US6699492B2 (en) * 1999-03-31 2004-03-02 Insite Vision Incorporated Quinolone carboxylic acid compositions and related methods of treatment
US20030018044A1 (en) * 2000-02-18 2003-01-23 Peyman Gholam A. Treatment of ocular disease
AU2001261748A1 (en) * 2000-05-19 2001-12-03 Alcon Laboratories Inc. Antibiotic compositions for treatment of the eye, ear and nose
US6495164B1 (en) * 2000-05-25 2002-12-17 Alkermes Controlled Therapeutics, Inc. I Preparation of injectable suspensions having improved injectability
KR20030061390A (ko) * 2000-11-01 2003-07-18 메르크 파텐트 게엠베하 안구 질환 치료용 조성물 및 방법
US7354574B2 (en) * 2002-11-07 2008-04-08 Advanced Ocular Systems Limited Treatment of ocular disease
US7083802B2 (en) * 2003-07-31 2006-08-01 Advanced Ocular Systems Limited Treatment of ocular disease
US7417056B2 (en) * 2004-11-12 2008-08-26 Schering Ag 5-substituted quinoline and isoquinoline derivatives, a process for their production and their use as anti-inflammatory agents
BRPI0606172A2 (pt) * 2005-06-08 2009-06-02 Targegen Inc métodos e composições para o tratamento de distúrbios oculares
JP2010500364A (ja) * 2006-08-07 2010-01-07 ボーシュ アンド ローム インコーポレイティド 後部眼科疾患を治療、または軽減、または改善、または緩和するための組成物と方法
PL2056799T3 (pl) * 2006-08-31 2014-01-31 Bausch & Lomb Kompozycje i sposoby do leczenia lub zapobiegania jaskrze lub jej rozwojowi
PL2061444T3 (pl) * 2006-09-11 2011-09-30 Bausch & Lomb Kompozycje i sposoby leczenia, traktowania, kontrolowania, redukowania, łagodzenia lub zapobiegania alergii
JP2010529133A (ja) * 2007-06-11 2010-08-26 ボーシュ アンド ローム インコーポレイティド フルオロキノロンを用いて炎症を調節するための組成物と方法
US20090082337A1 (en) * 2007-09-21 2009-03-26 Srini Venkastesh Compositions Comprising Quinolone and Methods for Treating or Controlling Infections

Also Published As

Publication number Publication date
CA2703000C (en) 2013-08-06
KR20100067684A (ko) 2010-06-21
HK1144073A1 (en) 2011-01-28
BRPI0819175A2 (pt) 2015-05-05
WO2009061607A2 (en) 2009-05-14
EP2214644B1 (en) 2013-03-20
US20100286121A1 (en) 2010-11-11
AU2008325036B2 (en) 2011-10-20
EP2214644A2 (en) 2010-08-11
ES2402321T3 (es) 2013-04-30
AU2008325036A1 (en) 2009-05-14
SG185955A1 (en) 2012-12-28
JP2011502990A (ja) 2011-01-27
CA2703000A1 (en) 2009-05-14
CN101848701A (zh) 2010-09-29
WO2009061607A3 (en) 2009-07-02

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