JP6581194B2 - 眼用インプラント送達装置および方法 - Google Patents
眼用インプラント送達装置および方法 Download PDFInfo
- Publication number
- JP6581194B2 JP6581194B2 JP2017523187A JP2017523187A JP6581194B2 JP 6581194 B2 JP6581194 B2 JP 6581194B2 JP 2017523187 A JP2017523187 A JP 2017523187A JP 2017523187 A JP2017523187 A JP 2017523187A JP 6581194 B2 JP6581194 B2 JP 6581194B2
- Authority
- JP
- Japan
- Prior art keywords
- implant
- guide sleeve
- shell
- syringe
- central channel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Prostheses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462024682P | 2014-07-15 | 2014-07-15 | |
| US62/024,682 | 2014-07-15 | ||
| PCT/US2015/040633 WO2016011191A1 (en) | 2014-07-15 | 2015-07-15 | Ocular implant delivery device and method |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017521219A JP2017521219A (ja) | 2017-08-03 |
| JP2017521219A5 JP2017521219A5 (enExample) | 2018-08-23 |
| JP6581194B2 true JP6581194B2 (ja) | 2019-09-25 |
Family
ID=55079028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523187A Active JP6581194B2 (ja) | 2014-07-15 | 2015-07-15 | 眼用インプラント送達装置および方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US10258503B2 (enExample) |
| EP (2) | EP3679908B1 (enExample) |
| JP (1) | JP6581194B2 (enExample) |
| KR (1) | KR102416726B1 (enExample) |
| CN (1) | CN106687079B (enExample) |
| AU (1) | AU2015289625B2 (enExample) |
| BR (1) | BR112017000774B1 (enExample) |
| CA (1) | CA2955186C (enExample) |
| ES (2) | ES2803102T3 (enExample) |
| IL (1) | IL250079B (enExample) |
| MX (1) | MX384889B (enExample) |
| MY (1) | MY182497A (enExample) |
| RU (1) | RU2695563C2 (enExample) |
| WO (1) | WO2016011191A1 (enExample) |
| ZA (1) | ZA201700387B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG2014007389A (en) | 2009-01-29 | 2014-04-28 | Forsight Vision4 Inc | Posterior segment drug delivery |
| US10010448B2 (en) | 2012-02-03 | 2018-07-03 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| WO2014160884A1 (en) | 2013-03-28 | 2014-10-02 | Forsight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
| RU2695563C2 (ru) | 2014-07-15 | 2019-07-24 | Форсайт Вижн4, Инк. | Способ и устройство для доставки глазного имплантата |
| EP3179968B1 (en) | 2014-07-24 | 2019-09-11 | Sinopsys Surgical, Inc. | Paranasal sinus access implant devices and related products and methods |
| JP2017524034A (ja) | 2014-08-08 | 2017-08-24 | フォーサイト・ビジョン フォー・インコーポレーテッドForsight Vision4, Inc. | 受容体型チロシンキナーゼ阻害剤の安定で可溶な製剤およびその調製の方法 |
| KR20170106298A (ko) | 2014-11-10 | 2017-09-20 | 포사이트 비젼4, 인크. | 확장 가능한 약물 전달 장치 및 이용 방법 |
| EP3377009B1 (en) | 2015-11-20 | 2020-10-28 | ForSight Vision4, Inc. | Porous structures for extended release drug delivery devices |
| CN113017981B (zh) | 2016-04-05 | 2023-07-25 | 弗赛特影像4股份有限公司 | 药物递送装置 |
| ES3012747T3 (en) * | 2017-09-20 | 2025-04-10 | Sinopsys Surgical Inc | Paranasal sinus fluid access implantation tools and assemblies |
| EP3713528A1 (en) | 2017-11-21 | 2020-09-30 | ForSight Vision4, Inc. | Fluid exchange apparatus for expandable port delivery system and methods of use |
| EP3698758A1 (en) * | 2019-02-20 | 2020-08-26 | Leibniz-Institut für Polymerforschung Dresden e.V. | Device and assemblies for oriented transport, microscopic investigation and oriented ejection of a tissue graft or implant |
| CN110507476B (zh) * | 2019-09-12 | 2021-10-26 | 格劳科斯公司 | 制造眼部植入物输送装置的方法 |
| WO2021170812A1 (en) * | 2020-02-27 | 2021-09-02 | Istar Medical Sa | Package for retaining and dispensing a delivery shaft assembly for delivery of an implant |
| CN115209835A (zh) * | 2020-02-27 | 2022-10-18 | 伊斯塔尔医疗公司 | 用于保持和分配用于输送植入物的输送轴组件的包装件 |
| US20220054311A1 (en) * | 2020-08-12 | 2022-02-24 | United States Government As Represented By The Department Of Veterans Affairs | Eye Drop Dispensing Apparatus |
| US12268633B2 (en) | 2020-11-04 | 2025-04-08 | Alcon Inc. | Medical implant |
| JP2024535191A (ja) | 2021-09-20 | 2024-09-30 | モット・コーポレーション | 医療機器用ポリマーコーティング及びその製造方法 |
| USD1037439S1 (en) | 2022-01-17 | 2024-07-30 | EyePoint Pharamaceuticals, Inc. | Ocular injector |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
| CN114848289B (zh) * | 2022-05-06 | 2025-02-14 | 海思盖德(苏州)生物医学科技有限公司 | 一种眼部植入物输送器 |
| CN114983670B (zh) * | 2022-05-30 | 2025-08-01 | 海思盖德(苏州)生物医学科技有限公司 | 一种眼内植入物输送器 |
| USD1101145S1 (en) | 2022-08-11 | 2025-11-04 | Genentech, Inc. | Ocular incision guide tool |
| CN118512302B (zh) * | 2024-07-23 | 2024-10-01 | 苏州朗目医疗科技有限公司 | 一种眼用缓释药输送系统 |
Family Cites Families (369)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2585815A (en) | 1947-01-16 | 1952-02-12 | Mclintock Duncan Menzies | Injection syringe |
| US2564977A (en) | 1949-01-19 | 1951-08-21 | Hu Quang Hsi | Medical injecting apparatus |
| US3232117A (en) | 1962-09-14 | 1966-02-01 | Roger Gilmont Instr Inc | Micrometer buret |
| US3416530A (en) | 1966-03-02 | 1968-12-17 | Richard A. Ness | Eyeball medication dispensing tablet |
| US3538916A (en) * | 1968-12-19 | 1970-11-10 | Joseph S Wiles | Injection pistol |
| US3618604A (en) | 1969-06-09 | 1971-11-09 | Alza Corp | Ocular insert |
| US3641237A (en) | 1970-09-30 | 1972-02-08 | Nat Patent Dev Corp | Zero order release constant elution rate drug dosage |
| US4034756A (en) | 1971-01-13 | 1977-07-12 | Alza Corporation | Osmotically driven fluid dispenser |
| US3995635A (en) | 1971-09-09 | 1976-12-07 | Alza Corporation | Ocular insert |
| US3828777A (en) | 1971-11-08 | 1974-08-13 | Alza Corp | Microporous ocular device |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US3902495A (en) | 1974-01-28 | 1975-09-02 | Cavitron Corp | Flow control system |
| US3961628A (en) | 1974-04-10 | 1976-06-08 | Alza Corporation | Ocular drug dispensing system |
| US3949748A (en) | 1974-09-26 | 1976-04-13 | Oscar Malmin | Injection syringe having aspirating and metering capabilities |
| US3949750A (en) | 1974-10-07 | 1976-04-13 | Freeman Jerre M | Punctum plug and method for treating keratoconjunctivitis sicca (dry eye) and other ophthalmic aliments using same |
| US4135514A (en) | 1974-12-23 | 1979-01-23 | Alza Corporation | Osmotic releasing system for administering ophthalmic drug to eye of animal |
| US4014335A (en) | 1975-04-21 | 1977-03-29 | Alza Corporation | Ocular drug delivery device |
| US3977404A (en) | 1975-09-08 | 1976-08-31 | Alza Corporation | Osmotic device having microporous reservoir |
| US4034758A (en) | 1975-09-08 | 1977-07-12 | Alza Corporation | Osmotic therapeutic system for administering medicament |
| US4014333A (en) | 1975-09-22 | 1977-03-29 | Mcintyre David J | Instrument for aspirating and irrigating during ophthalmic surgery |
| US4077407A (en) | 1975-11-24 | 1978-03-07 | Alza Corporation | Osmotic devices having composite walls |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4014334A (en) | 1976-02-02 | 1977-03-29 | Alza Corporation | Laminated osmotic system for dispensing beneficial agent |
| US4111201A (en) | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for delivering selected beneficial agents having varying degrees of solubility |
| US4111203A (en) | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system with means for improving delivery kinetics of system |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4160452A (en) | 1977-04-07 | 1979-07-10 | Alza Corporation | Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina |
| US4220152A (en) | 1978-05-08 | 1980-09-02 | Pfizer Inc. | Delivery system |
| US4220153A (en) | 1978-05-08 | 1980-09-02 | Pfizer Inc. | Controlled release delivery system |
| US4200098A (en) | 1978-10-23 | 1980-04-29 | Alza Corporation | Osmotic system with distribution zone for dispensing beneficial agent |
| US4298000A (en) | 1978-11-08 | 1981-11-03 | Minnesota Mining And Manufacturing Company | Fluid dispensing device |
| US4300557A (en) | 1980-01-07 | 1981-11-17 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for treating intraocular malignancies |
| US4309776A (en) | 1980-05-13 | 1982-01-12 | Ramon Berguer | Intravascular implantation device and method of using the same |
| US4326525A (en) | 1980-10-14 | 1982-04-27 | Alza Corporation | Osmotic device that improves delivery properties of agent in situ |
| US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| US4484922A (en) | 1981-06-25 | 1984-11-27 | Rosenwald Peter L | Occular device |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4475916A (en) | 1982-03-18 | 1984-10-09 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4519801A (en) | 1982-07-12 | 1985-05-28 | Alza Corporation | Osmotic device with wall comprising cellulose ether and permeability enhancer |
| US4673405A (en) | 1983-03-04 | 1987-06-16 | Alza Corporation | Osmotic system with instant drug availability |
| US4883459A (en) | 1983-07-29 | 1989-11-28 | Reynaldo Calderon | Retrograde perfusion |
| US4627850A (en) | 1983-11-02 | 1986-12-09 | Alza Corporation | Osmotic capsule |
| US4777049A (en) | 1983-12-01 | 1988-10-11 | Alza Corporation | Constant release system with pulsed release |
| US4712550A (en) | 1985-04-08 | 1987-12-15 | Sinnett Kevin B | Retinal tack |
| US4693886A (en) | 1985-04-22 | 1987-09-15 | Alza Corporation | Osmotic device with inert core |
| US4609374A (en) | 1985-04-22 | 1986-09-02 | Alza Corporation | Osmotic device comprising means for governing initial time of agent release therefrom |
| EP0201611A1 (de) | 1985-05-10 | 1986-11-20 | B. Braun-SSC AG | Zwei-Kanülen-Spritze |
| CA1314481C (en) | 1986-12-23 | 1993-03-16 | Marcel B. Bally | Liposomal preparation and antibiotic |
| EP0228185B1 (en) | 1985-11-27 | 1990-07-25 | Thomas C. White | Tissue-implantable fluid-dissipating device |
| US4781675A (en) | 1985-11-27 | 1988-11-01 | White Thomas C | Infusion cannula |
| US4959217A (en) | 1986-05-22 | 1990-09-25 | Syntex (U.S.A.) Inc. | Delayed/sustained release of macromolecules |
| US5322691A (en) | 1986-10-02 | 1994-06-21 | Sohrab Darougar | Ocular insert with anchoring protrusions |
| US4863457A (en) | 1986-11-24 | 1989-09-05 | Lee David A | Drug delivery device |
| US4865846A (en) | 1988-06-03 | 1989-09-12 | Kaufman Herbert E | Drug delivery system |
| US5174999A (en) | 1988-12-13 | 1992-12-29 | Alza Corporation | Delivery system comprising fluid ingress and drug egress |
| WO1990007575A1 (en) | 1988-12-30 | 1990-07-12 | Anderson David M | Stabilized microporous materials and hydrogel materials |
| US5098443A (en) | 1989-03-23 | 1992-03-24 | University Of Miami | Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents |
| US5164188A (en) | 1989-11-22 | 1992-11-17 | Visionex, Inc. | Biodegradable ocular implants |
| US5324280A (en) | 1990-04-02 | 1994-06-28 | Alza Corporation | Osmotic dosage system for delivering a formulation comprising liquid carrier and drug |
| US5128145A (en) | 1990-06-13 | 1992-07-07 | Alza Corporation | Dosage form for Parkinson's disease, spasticity and muscle spasms |
| US5084021A (en) | 1990-11-02 | 1992-01-28 | Baldwin Brian E | Patient controlled infusion apparatus and method |
| US5378475A (en) | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
| AU650113B2 (en) | 1991-04-05 | 1994-06-09 | Eli Lilly And Company | Sustained release capsule and formulations |
| US5334189A (en) | 1991-06-03 | 1994-08-02 | Wade Stephen E | Device for controlled diffusion of a chemical substance |
| US5282829A (en) | 1991-08-15 | 1994-02-01 | United States Surgical Corporation | Hollow body implants |
| FR2682090B1 (fr) | 1991-10-03 | 1993-12-31 | Holzstoff Holding Sa | Systeme-reservoir pour diffusion prolongee d'un principe actif. |
| US5681572A (en) | 1991-10-18 | 1997-10-28 | Seare, Jr.; William J. | Porous material product and process |
| US5178622A (en) | 1991-11-01 | 1993-01-12 | Lehner Ii Robert H | Instrument for implanting a soft intraocular lens |
| US5178635A (en) | 1992-05-04 | 1993-01-12 | Allergan, Inc. | Method for determining amount of medication in an implantable device |
| US6096756A (en) | 1992-09-21 | 2000-08-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| US5336175A (en) | 1992-10-29 | 1994-08-09 | Mames Robert N | Method for the treatment of retinal detachments |
| US5443505A (en) | 1993-11-15 | 1995-08-22 | Oculex Pharmaceuticals, Inc. | Biocompatible ocular implants |
| CA2140053C (en) | 1994-02-09 | 2000-04-04 | Joel S. Rosenblatt | Collagen-based injectable drug delivery system and its use |
| US5770076A (en) | 1994-03-07 | 1998-06-23 | The Regents Of The University Of California | Micromachined capsules having porous membranes and bulk supports |
| US5985328A (en) | 1994-03-07 | 1999-11-16 | Regents Of The University Of California | Micromachined porous membranes with bulk support |
| US5516522A (en) | 1994-03-14 | 1996-05-14 | Board Of Supervisors Of Louisiana State University | Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same |
| US5466233A (en) | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
| AUPM897594A0 (en) | 1994-10-25 | 1994-11-17 | Daratech Pty Ltd | Controlled release container |
| WO1996014834A1 (en) | 1994-11-10 | 1996-05-23 | University Of Kentucky Research Foundation | Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body |
| US5725493A (en) | 1994-12-12 | 1998-03-10 | Avery; Robert Logan | Intravitreal medicine delivery |
| US5554132A (en) | 1995-03-30 | 1996-09-10 | Abbott Laboratories | Hand grip for use with syringe |
| CN1283324C (zh) | 1995-05-14 | 2006-11-08 | 奥普通诺尔有限公司 | 眼内植入物、植入装置、以及植入方法 |
| IL113723A (en) | 1995-05-14 | 2002-11-10 | Optonol Ltd | Intraocular implant |
| US5609629A (en) | 1995-06-07 | 1997-03-11 | Med Institute, Inc. | Coated implantable medical device |
| US6685940B2 (en) | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| US5773019A (en) | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
| US6641708B1 (en) | 1996-01-31 | 2003-11-04 | Board Of Regents, The University Of Texas System | Method and apparatus for fractionation using conventional dielectrophoresis and field flow fractionation |
| GB2310149A (en) | 1996-02-15 | 1997-08-20 | Nomix Chipman Ltd | Spray gun |
| US20090005864A1 (en) | 1996-03-18 | 2009-01-01 | Eggleston Harry C | Modular intraocular implant |
| US5951512A (en) | 1996-05-28 | 1999-09-14 | Horizon Medical Products, Inc. | Infusion port with modified drug reservoir |
| US5797898A (en) | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
| US5928662A (en) | 1996-07-31 | 1999-07-27 | Phillips; Andrew F. | Ocular drug delivery device |
| AU7533696A (en) | 1996-12-13 | 1998-06-18 | Ciba-Geigy Ag | New materials |
| CA2284058C (en) | 1997-03-31 | 2007-02-20 | Alza Corporation | Diffusional implantable delivery system |
| US7160687B1 (en) | 1997-05-29 | 2007-01-09 | Cellomics, Inc. | Miniaturized cell array methods and apparatus for cell-based screening |
| US5902598A (en) | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
| US6039712A (en) | 1997-11-04 | 2000-03-21 | Terence M. Fogarty | Implantable injection port |
| US8313454B2 (en) * | 1997-11-20 | 2012-11-20 | Optonol Ltd. | Fluid drainage device, delivery device, and associated methods of use and manufacture |
| KR100246044B1 (ko) * | 1998-02-20 | 2000-03-15 | 성재갑 | 투여장치 |
| US6196993B1 (en) | 1998-04-20 | 2001-03-06 | Eyelab Group, Llc | Ophthalmic insert and method for sustained release of medication to the eye |
| FR2784296B1 (fr) | 1998-09-18 | 2001-01-05 | Imedex Biomateriaux | Dispositif pour la formulation et la delivrance d'un melange, notamment pour l'application chirurgicale de ce melange |
| US7973068B2 (en) | 1998-10-20 | 2011-07-05 | Omeros Corporation | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation |
| DE19948783C2 (de) | 1999-02-18 | 2001-06-13 | Alcove Surfaces Gmbh | Implantat |
| US7914442B1 (en) | 1999-03-01 | 2011-03-29 | Gazdzinski Robert F | Endoscopic smart probe and method |
| US6395300B1 (en) | 1999-05-27 | 2002-05-28 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| US6472162B1 (en) | 1999-06-04 | 2002-10-29 | Thermogenesis Corp. | Method for preparing thrombin for use in a biological glue |
| EP1187617B1 (en) | 1999-06-18 | 2004-03-03 | Alcon Manufacturing Ltd. | Method for selecting the concentration of an amphipathic antihistamine drug by determining the drug's surface activity rating |
| US6638263B1 (en) | 1999-10-12 | 2003-10-28 | Durect Corporation | Regulation of drug delivery through flow diversion |
| US6416777B1 (en) | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
| PT1473003E (pt) | 1999-10-21 | 2008-12-26 | Alcon Inc | Dispositivo para administração de fármacos |
| US6331313B1 (en) | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| US20030212383A1 (en) | 2001-01-05 | 2003-11-13 | Dana Cote | System and methods for reducing intraocular pressure |
| US20050119737A1 (en) | 2000-01-12 | 2005-06-02 | Bene Eric A. | Ocular implant and methods for making and using same |
| WO2001050943A2 (en) | 2000-01-12 | 2001-07-19 | Becton, Dickinson And Company | Systems and methods for reducing intraocular pressure |
| US7077848B1 (en) | 2000-03-11 | 2006-07-18 | John Hopkins University | Sutureless occular surgical methods and instruments for use in such methods |
| WO2001068377A1 (en) | 2000-03-13 | 2001-09-20 | Seiko Epson Corporation | Method for surface treatment, surface-treated article and device for surface treatment |
| US7141152B2 (en) | 2000-03-16 | 2006-11-28 | Le Febre David A | Analyte species separation system |
| US6375972B1 (en) | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
| US6478800B1 (en) * | 2000-05-08 | 2002-11-12 | Depuy Acromed, Inc. | Medical installation tool |
| US8251946B2 (en) * | 2000-08-24 | 2012-08-28 | Cardiac Science, Inc. | Method for constructing an instrument with a two-part plunger for subcutaneous implantation |
| CA2420038C (en) | 2000-08-30 | 2010-11-09 | John Hopkins University | Devices for intraocular drug delivery |
| EP1337284B1 (en) | 2000-09-06 | 2007-12-05 | Alcon Inc. | Switchable tackiness coating compositions for ophthalmic implants |
| US6303290B1 (en) | 2000-09-13 | 2001-10-16 | The Trustees Of The University Of Pennsylvania | Encapsulation of biomaterials in porous glass-like matrices prepared via an aqueous colloidal sol-gel process |
| EP1345588A2 (en) | 2000-12-29 | 2003-09-24 | Bausch & Lomb Incorporated | Sustained release drug delivery devices |
| WO2002053128A2 (en) | 2001-01-03 | 2002-07-11 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with multiple agents |
| JP2004521882A (ja) | 2001-01-03 | 2004-07-22 | ボシュ・アンド・ロム・インコーポレイテッド | 組立式透過性プラグを備えた徐放薬剤送達装置 |
| US20020086051A1 (en) | 2001-01-03 | 2002-07-04 | Santos Viscasillas | Sustained release drug delivery devices with coated drug cores |
| US6976982B2 (en) | 2001-01-09 | 2005-12-20 | Microchips, Inc. | Flexible microchip devices for ophthalmic and other applications |
| CA2433528A1 (en) | 2001-01-26 | 2002-08-01 | Bausch & Lomb Incorporated | Improved process for the production of sustained release drug delivery devices |
| US7181287B2 (en) | 2001-02-13 | 2007-02-20 | Second Sight Medical Products, Inc. | Implantable drug delivery device |
| US6713081B2 (en) | 2001-03-15 | 2004-03-30 | The United States Of America As Represented By The Department Of Health And Human Services | Ocular therapeutic agent delivery devices and methods for making and using such devices |
| US20020133168A1 (en) * | 2001-03-16 | 2002-09-19 | Smedley Gregory T. | Applicator and methods for placing a trabecular shunt for glaucoma treatment |
| EP1404297B1 (en) | 2001-06-12 | 2011-04-27 | The Johns Hopkins University School Of Medicine | Reservoir device for intraocular drug delivery |
| US7195778B2 (en) | 2001-07-10 | 2007-03-27 | Teva Pharmaceutical Industries Ltd. | Drug delivery system for zero order, zero order-biphasic, ascending or descending drug delivery |
| IL144446A0 (en) | 2001-07-19 | 2002-05-23 | Prochon Biotech Ltd | Plasma protein matrices and methods for their preparation |
| DE60217679T2 (de) | 2001-07-23 | 2007-10-25 | Alcon Inc. | Vorrichtung zur freisetzung eines ophthalmischen arzneimittels |
| ES2271301T3 (es) | 2001-07-23 | 2007-04-16 | Alcon, Inc. | Dispositivo de suministro de farmaco oftalmico. |
| US7749528B2 (en) | 2001-08-29 | 2010-07-06 | Ricardo Azevedo Pontes De Carvalho | Implantable and sealable medical device for unidirectional delivery of therapeutic agents to tissues |
| EP1420716B1 (en) | 2001-08-29 | 2012-08-15 | Ricardo A. P. De Carvalho | An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues |
| US20030118649A1 (en) | 2001-10-04 | 2003-06-26 | Jinming Gao | Drug delivery devices and methods |
| US8663687B2 (en) | 2001-10-12 | 2014-03-04 | Monosol Rx, Llc | Film compositions for delivery of actives |
| EP1444338A4 (en) | 2001-11-15 | 2007-07-04 | Arryx Inc | PASTILLE WITH SAMPLES |
| GB2399753B (en) | 2002-01-18 | 2006-04-19 | Michael E Snyder | Method of making a sustained release ophthalmological device |
| US8364229B2 (en) | 2003-07-25 | 2013-01-29 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| KR101191254B1 (ko) | 2002-03-11 | 2012-10-16 | 알콘, 인코퍼레이티드 | 이식 가능한 약물 전달 시스템 |
| US7074426B2 (en) | 2002-03-27 | 2006-07-11 | Frank Kochinke | Methods and drug delivery systems for the treatment of orofacial diseases |
| US7939094B2 (en) | 2002-06-19 | 2011-05-10 | Boston Scientific Scimed, Inc. | Multiphase polymeric drug release region |
| PT1521572E (pt) | 2002-07-15 | 2009-04-21 | Alcon Inc | Película bioerodível para administração oftálmica de fármacos |
| US8425549B2 (en) | 2002-07-23 | 2013-04-23 | Reverse Medical Corporation | Systems and methods for removing obstructive matter from body lumens and treating vascular defects |
| US20040019325A1 (en) | 2002-07-29 | 2004-01-29 | Medrip Ltd. | Syringe Pump |
| PL223153B1 (pl) | 2002-09-18 | 2016-10-31 | Allergan Inc | Urządzenie do wszczepiania implantu okulistycznego |
| US7468065B2 (en) | 2002-09-18 | 2008-12-23 | Allergan, Inc. | Apparatus for delivery of ocular implants |
| AU2003279055A1 (en) | 2002-09-29 | 2004-04-19 | Surmodics, Inc. | Methods for treatment and/or prevention of retinal disease |
| WO2004066871A2 (en) | 2003-01-24 | 2004-08-12 | Doheny Retina Institute | Reservoirs with subretinal cannula for subretinal drug delivery |
| WO2004073551A2 (en) | 2003-02-18 | 2004-09-02 | Massachusetts Eye And Ear Infirmary | Transscleral drug delivery device and related methods |
| WO2004076647A2 (en) | 2003-02-26 | 2004-09-10 | The Regents Of The University Of California | Use of steady-state oxygen gradients to modulate animal cell functions |
| US20050074497A1 (en) | 2003-04-09 | 2005-04-07 | Schultz Clyde L. | Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases |
| US20050255144A1 (en) | 2003-04-09 | 2005-11-17 | Directcontact Llc | Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases |
| EP1671624B1 (en) | 2003-05-02 | 2010-08-11 | SurModics, Inc. | Delivery device for a controlled drug release of an active agent into the posterior section of the eye |
| EP1633320A2 (en) | 2003-05-02 | 2006-03-15 | SurModics, Inc. | Implantable controlled release bioactive agent delivery device |
| US8403941B2 (en) * | 2003-06-02 | 2013-03-26 | Abbott Medical Optics Inc. | Intraocular lens and cartridge packaging with lens-loading function |
| JP2007500251A (ja) | 2003-06-13 | 2007-01-11 | ベクトン・ディキンソン・アンド・カンパニー | 生物学的に活性な作用物質の改良型皮内送達 |
| US20040260380A1 (en) | 2003-06-18 | 2004-12-23 | D-Crown Ltd | Devices for delivering multiple stenting structures in situ |
| WO2004112653A2 (en) | 2003-06-18 | 2004-12-29 | D-Crown Ltd. | Devices and methods for delivering and forming single and multiple stenting structures in situ |
| US20040260381A1 (en) | 2003-06-18 | 2004-12-23 | D-Crown Ltd | Devices and methods for forming stenting structures in situ |
| WO2005007233A2 (en) | 2003-06-20 | 2005-01-27 | Massachusetts Institute Of Technology | Application of electrical stimulation for functional tissue engineering in vitro and in vivo |
| CN1805719A (zh) | 2003-07-10 | 2006-07-19 | 爱尔康公司 | 眼药输送装置 |
| FI120333B (fi) | 2003-08-20 | 2009-09-30 | Bioretec Oy | Huokoinen lääketieteellinen väline ja menetelmä sen valmistamiseksi |
| US7252673B2 (en) * | 2003-09-10 | 2007-08-07 | Warsaw Orthopedic, Inc. | Devices and methods for inserting spinal implants |
| JP2007505932A (ja) | 2003-09-18 | 2007-03-15 | マクサイト, インコーポレイテッド | 経強膜送達 |
| US20050181018A1 (en) | 2003-09-19 | 2005-08-18 | Peyman Gholam A. | Ocular drug delivery |
| WO2005028006A1 (en) | 2003-09-24 | 2005-03-31 | Medi-Stream Pty Ltd | Medication holder |
| AU2006225241B2 (en) | 2003-09-24 | 2008-07-17 | Tianda Pharmaceuticals (Australia) Pty Limited | Medication Holder |
| US7615141B2 (en) | 2003-10-03 | 2009-11-10 | University Of Washington | Electrochemical micromanufacturing system and method |
| US7211272B2 (en) | 2003-12-22 | 2007-05-01 | Bausch & Lomb Incorporated | Drug delivery device |
| WO2005079915A1 (en) | 2004-02-12 | 2005-09-01 | Neo Vista, Inc. | Methods and apparatus for intraocular brachytherapy |
| US7276050B2 (en) | 2004-03-02 | 2007-10-02 | Alan Franklin | Trans-scleral drug delivery method and apparatus |
| US20050256499A1 (en) | 2004-03-03 | 2005-11-17 | Pettis Ronald J | Methods and devices for improving delivery of a substance to skin |
| EP1737393B1 (de) | 2004-04-22 | 2010-06-09 | Advanced Vision Science, Inc. | Vorrichtung zum einsetzen verformbarer intraocularlinsen |
| US20070059336A1 (en) | 2004-04-30 | 2007-03-15 | Allergan, Inc. | Anti-angiogenic sustained release intraocular implants and related methods |
| US8591885B2 (en) | 2004-04-30 | 2013-11-26 | Allergan, Inc. | Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems |
| US20060182783A1 (en) | 2004-04-30 | 2006-08-17 | Allergan, Inc. | Sustained release intraocular drug delivery systems |
| US20050244469A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Extended therapeutic effect ocular implant treatments |
| WO2005110374A1 (en) | 2004-04-30 | 2005-11-24 | Allergan, Inc. | Intraocular drug delivery systems containing a therapeutic component, a cyclodextrin, and a polymeric component |
| US8685435B2 (en) | 2004-04-30 | 2014-04-01 | Allergan, Inc. | Extended release biodegradable ocular implants |
| US20060110428A1 (en) | 2004-07-02 | 2006-05-25 | Eugene Dejuan | Methods and devices for the treatment of ocular conditions |
| US7117870B2 (en) | 2004-07-26 | 2006-10-10 | Clarity Corporation | Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same |
| JP2008509157A (ja) | 2004-08-06 | 2008-03-27 | ソフェリオン セラピューティクス,インコーポレイテッド | 抗血管新生ペプチドおよびその使用方法 |
| WO2006031358A2 (en) | 2004-08-13 | 2006-03-23 | Hyperbranch Medical Technology, Inc. | Dendritic polymers, crosslinked gels, and their uses as ophthalmic sealants and lenses |
| WO2006023530A2 (en) | 2004-08-16 | 2006-03-02 | Massachusetts Institute Of Technology | Compositions and methods for enhancing structural and functional nervous system reorganization and recovery |
| WO2006031388A2 (en) | 2004-08-20 | 2006-03-23 | Hyperbranch Medical Technology, Inc. | Dentritic polymers, crosslinked gels, and their uses in orthopedic applications |
| US20060052754A1 (en) | 2004-09-04 | 2006-03-09 | Fields Douglas W | Thumb trigger syringe pole |
| US7709049B2 (en) | 2004-09-10 | 2010-05-04 | Surmodics, Inc. | Methods, devices, and coatings for controlled active agent release |
| MX2007003968A (es) | 2004-10-01 | 2008-03-04 | Ramscor Inc | Composiciones de farmaco de liberacion sostenida convenientemente implantables. |
| US20080038316A1 (en) | 2004-10-01 | 2008-02-14 | Wong Vernon G | Conveniently implantable sustained release drug compositions |
| CA2583399A1 (en) | 2004-10-14 | 2006-04-27 | Sopherion Therapeutics, Inc. | Anti-angiogenic peptides and methods of use thereof |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| US20060129215A1 (en) | 2004-12-09 | 2006-06-15 | Helmus Michael N | Medical devices having nanostructured regions for controlled tissue biocompatibility and drug delivery |
| US20060154981A1 (en) | 2005-01-12 | 2006-07-13 | Alcon, Inc. | Method of reducing intraocular pressure and treating glaucoma |
| US20080233053A1 (en) | 2005-02-07 | 2008-09-25 | Pharmalight Inc. | Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients |
| US20060233858A1 (en) | 2005-03-08 | 2006-10-19 | Allergan, Inc. | Systems and methods providing targeted intraocular drug delivery |
| JP2008533204A (ja) | 2005-03-21 | 2008-08-21 | マクサイト, インコーポレイテッド | 病気又は症状の治療のためのドラッグ送達システム |
| US20070077270A1 (en) | 2005-03-28 | 2007-04-05 | Clemson University | Delivery devices and methods for long-term, targeted delivery of therapeutic agents to the eye and ear |
| CA2601351A1 (en) | 2005-03-30 | 2006-10-05 | Nulens Ltd | Accommodating intraocular lens (aiol) assemblies, and discrete components therfor |
| EP1875560A4 (en) | 2005-04-05 | 2011-02-09 | Univ Ohio State | DIFFUSION DELIVERY SYSTEMS AND MANUFACTURING METHOD |
| US20100168535A1 (en) | 2006-04-12 | 2010-07-01 | Mark Ries Robinson | Methods and apparatuses related to blood analyte measurement system |
| US20060258994A1 (en) | 2005-05-12 | 2006-11-16 | Avery Robert L | Implantable delivery device for administering pharmacological agents to an internal portion of a body |
| CN101198301A (zh) | 2005-05-18 | 2008-06-11 | 苏尔莫迪克斯公司 | 用于非线性医用装置的插入器械 |
| US20070088414A1 (en) | 2005-05-25 | 2007-04-19 | Campbell Robert L | Particulate formulations for intradermal delivery of biologically active agents |
| US20060276738A1 (en) | 2005-06-06 | 2006-12-07 | Becker Bruce B | Lacrimal drainage bypass device and method |
| US20070021357A1 (en) | 2005-06-17 | 2007-01-25 | Dynamis Therapeutics, Inc. | Treatment of inflammatory conditions |
| US7893040B2 (en) | 2005-07-22 | 2011-02-22 | Oculis Ehf | Cyclodextrin nanotechnology for ophthalmic drug delivery |
| US8663673B2 (en) | 2005-07-29 | 2014-03-04 | Surmodics, Inc. | Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility |
| US20070060887A1 (en) * | 2005-08-22 | 2007-03-15 | Marsh David A | Ophthalmic injector |
| US20070212397A1 (en) | 2005-09-15 | 2007-09-13 | Roth Daniel B | Pharmaceutical delivery device and method for providing ocular treatment |
| JP2009508593A (ja) | 2005-09-16 | 2009-03-05 | (オーエスアイ)アイテツク・インコーポレーテツド | 眼科用シリンジ |
| WO2007038453A2 (en) | 2005-09-26 | 2007-04-05 | Advanced Ocular Systems Limited | Use of an anti-vascular endothelial growth factor (vegf) agent to ameliorate inflammation |
| US20080003219A1 (en) | 2005-09-26 | 2008-01-03 | Minu, L.L.C. | Delivery of an ocular agent |
| US20070071756A1 (en) | 2005-09-26 | 2007-03-29 | Peyman Gholam A | Delivery of an agent to ameliorate inflammation |
| US20080167600A1 (en) | 2005-09-26 | 2008-07-10 | Peyman Gholam A | Device for delivery of an agent to the eye and other sites |
| US20070072933A1 (en) | 2005-09-26 | 2007-03-29 | Peyman Gholam A | Delivery of an ocular agent |
| TW200732347A (en) | 2005-10-06 | 2007-09-01 | Trophogen Inc | VEGF analogs and methods of use |
| US8168584B2 (en) | 2005-10-08 | 2012-05-01 | Potentia Pharmaceuticals, Inc. | Methods of treating age-related macular degeneration by compstatin and analogs thereof |
| CA2625359A1 (en) | 2005-10-11 | 2007-04-19 | Blake Podaima | Smart medical compliance method and system |
| US20080125406A1 (en) | 2005-10-14 | 2008-05-29 | Robin Alan L | Method for Treating Primary and Secondary Forms of Glaucoma |
| BRPI0617414A2 (pt) | 2005-10-14 | 2011-07-26 | Alcon Inc | mÉtodo para tratamento de formas primÁrias e secundÁrias de glaucoma |
| JP4721425B2 (ja) | 2005-12-01 | 2011-07-13 | キヤノン株式会社 | 流体移動方法および流体移動装置 |
| JP5283509B2 (ja) | 2005-12-07 | 2013-09-04 | ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド | 薬物送達複合構造体 |
| US20070131611A1 (en) | 2005-12-13 | 2007-06-14 | General Electric Company | Membrane-based article and associated method |
| US20070131610A1 (en) | 2005-12-13 | 2007-06-14 | General Electric Company | Membrane-based apparatus and associated method |
| EP3632385B1 (en) | 2006-01-17 | 2024-08-07 | Alcon Inc. | Glaucoma treatment device |
| EP3338743A1 (en) | 2006-01-17 | 2018-06-27 | Novartis Ag | Drug delivery treatment device |
| US20080216736A1 (en) | 2006-01-19 | 2008-09-11 | Takeda San Diego, Inc. | Microfluidic device with diffusion between adjacent lumens |
| WO2007100986A2 (en) | 2006-02-24 | 2007-09-07 | Rosetta Inpharmatics Llc | Extraction and diagnostic fluid devices, systems and methods of use |
| WO2007101204A1 (en) | 2006-02-27 | 2007-09-07 | Alcon Research, Ltd. | Method of treating glaucoma |
| TW200800230A (en) | 2006-03-31 | 2008-01-01 | Dynamis Therapeutics Inc | Composition and method related to fructosamine-3-kinase inhibitors |
| KR20090006153A (ko) | 2006-03-31 | 2009-01-14 | 큐엘티 플러그 딜리버리, 인코포레이티드 | 비루관계에 대한 약물 전달 방법, 구조, 및 조성물 |
| EA013662B1 (ru) | 2006-04-18 | 2010-06-30 | Чжуншань Ботай Фармасьютик Инструментс Ко., Лтд. | Асептический шприц |
| US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
| WO2007131050A2 (en) | 2006-05-02 | 2007-11-15 | Georgia Tech Research Corporation | Method for drug delivery to ocular tissue using microneedle |
| US20080124372A1 (en) | 2006-06-06 | 2008-05-29 | Hossainy Syed F A | Morphology profiles for control of agent release rates from polymer matrices |
| EP2037882B1 (en) | 2006-06-28 | 2014-12-10 | SurModics, Inc. | Combination degradable and non-degradable matrices for active agent delivery |
| TW200815045A (en) | 2006-06-29 | 2008-04-01 | Jazz Pharmaceuticals Inc | Pharmaceutical compositions of ropinirole and methods of use thereof |
| JP5396272B2 (ja) * | 2006-06-30 | 2014-01-22 | アクエシス インコーポレイテッド | 臓器内圧力軽減のための方法、システムおよび装置 |
| WO2008009120A2 (en) | 2006-07-19 | 2008-01-24 | Noab Biodiscoveries Inc. | Method and device to extract components contained in a fluid |
| JP2009544355A (ja) | 2006-07-20 | 2009-12-17 | ニューロシステック コーポレイション | 眼科薬物送達のためのデバイス、システム、および方法 |
| US20080069854A1 (en) | 2006-08-02 | 2008-03-20 | Inframat Corporation | Medical devices and methods of making and using |
| US20080097335A1 (en) * | 2006-08-04 | 2008-04-24 | Allergan, Inc. | Ocular implant delivery assemblies |
| JP2008054521A (ja) | 2006-08-29 | 2008-03-13 | Canon Inc | 細胞培養処理装置及び細胞培養処理方法 |
| WO2008033924A2 (en) | 2006-09-12 | 2008-03-20 | Board Of Regents Of The University Of Nebraska | Methods and compositions for targeted delivery of therapeutic agents |
| US20080066739A1 (en) | 2006-09-20 | 2008-03-20 | Lemahieu Edward | Methods and systems of delivering medication via inhalation |
| US20080089923A1 (en) | 2006-09-29 | 2008-04-17 | Burkstrand Michael J | Biodegradable ocular implants and methods for treating ocular conditions |
| TW200817039A (en) | 2006-10-06 | 2008-04-16 | Dynamis Therapeutics Inc | Compositions and methods for skin lightening |
| US9022970B2 (en) | 2006-10-16 | 2015-05-05 | Alcon Research, Ltd. | Ophthalmic injection device including dosage control device |
| US8609148B2 (en) | 2006-10-25 | 2013-12-17 | Revalesio Corporation | Methods of therapeutic treatment of eyes |
| CA2667614A1 (en) | 2006-10-25 | 2008-09-25 | Revalesio Corporation | Method of wound care and treatment |
| US8784897B2 (en) | 2006-10-25 | 2014-07-22 | Revalesio Corporation | Methods of therapeutic treatment of eyes |
| JP5595041B2 (ja) | 2006-10-25 | 2014-09-24 | リバルシオ コーポレイション | 酸素富化溶液を用いる、眼および他のヒト組織の治療処置の方法 |
| US8784898B2 (en) | 2006-10-25 | 2014-07-22 | Revalesio Corporation | Methods of wound care and treatment |
| WO2008061043A2 (en) | 2006-11-10 | 2008-05-22 | Glaukos Corporation | Uveoscleral shunt and methods for implanting same |
| US20080111282A1 (en) | 2006-11-10 | 2008-05-15 | Baojun Xie | Process for Making Three Dimensional Objects From Dispersions of Polymer Colloidal Particles |
| US20100286791A1 (en) | 2006-11-21 | 2010-11-11 | Goldsmith David S | Integrated system for the ballistic and nonballistic infixion and retrieval of implants |
| JP2010511713A (ja) | 2006-12-05 | 2010-04-15 | ランデック コーポレイション | 薬物送達 |
| US20090263346A1 (en) | 2006-12-05 | 2009-10-22 | David Taft | Systems and methods for delivery of drugs |
| WO2008073295A2 (en) | 2006-12-07 | 2008-06-19 | Surmodics, Inc. | Latent stabilization of bioactive agents releasable from implantable medical articles |
| US20080147021A1 (en) | 2006-12-15 | 2008-06-19 | Jani Dharmendra M | Drug delivery devices |
| MX2009006146A (es) | 2006-12-18 | 2009-06-19 | Alcon Res Ltd | Dispositivos y metodos para la administracion de farmacos oftalmicos. |
| CA2674076A1 (en) * | 2006-12-26 | 2008-07-10 | Qlt Plug Delivery, Inc. | Drug delivery implants for inhibition of optical defects |
| EP2124857B1 (en) * | 2007-01-09 | 2017-03-29 | Fovea Pharmaceuticals | Apparatus for intra-ocular injection |
| US20080213611A1 (en) | 2007-01-19 | 2008-09-04 | Cinvention Ag | Porous, non-degradable implant made by powder molding |
| UY30883A1 (es) | 2007-01-31 | 2008-05-31 | Alcon Res | Tapones punctales y metodos de liberacion de agentes terapeuticos |
| US7905888B2 (en) | 2007-02-16 | 2011-03-15 | Brown David C | Apparatus for inserting flexible medical implant |
| WO2008116165A2 (en) | 2007-03-21 | 2008-09-25 | Next Safety, Inc. | Methods and systems of delivering medication via inhalation |
| US20080249501A1 (en) | 2007-04-09 | 2008-10-09 | Medtronic Vascular, Inc. | Methods for Simultaneous Injection and Aspiration of Fluids During a Medical Procedure |
| US20080286338A1 (en) | 2007-05-15 | 2008-11-20 | Boston Foundation For Sight | Drug delivery system with scleral lens |
| US8231892B2 (en) | 2007-05-24 | 2012-07-31 | Allergan, Inc. | Biodegradable drug delivery system |
| EP2164866B1 (en) | 2007-05-29 | 2014-05-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| US20090036827A1 (en) | 2007-07-31 | 2009-02-05 | Karl Cazzini | Juxtascleral Drug Delivery and Ocular Implant System |
| US9808557B2 (en) | 2007-08-10 | 2017-11-07 | Trustees Of Tufts College | Tubular silk compositions and methods of use thereof |
| CN101984745B (zh) | 2007-09-07 | 2013-08-14 | Qlt股份有限公司 | 用于持续释放治疗药物的药物核心 |
| NZ583832A (en) | 2007-09-07 | 2012-08-31 | Quadra Logic Tech Inc | Implant insertion tool with a tissue stop configuired to engage tissue |
| WO2009035571A2 (en) | 2007-09-07 | 2009-03-19 | Qlt Plug Delivery, Inc | Lacrimal implant detection |
| US8308755B2 (en) | 2007-09-24 | 2012-11-13 | Ethicon Endo-Surgery, Inc. | Elliptical retractor |
| US20090214601A1 (en) | 2007-09-28 | 2009-08-27 | Chappa Ralph A | Porous Drug Delivery Devices and Related Methods |
| RU2475282C2 (ru) | 2007-10-05 | 2013-02-20 | Тико Хелскеа Груп Лп | Герметизирующий фиксатор для использования при хирургических операциях |
| US10125359B2 (en) | 2007-10-25 | 2018-11-13 | Revalesio Corporation | Compositions and methods for treating inflammation |
| US9523090B2 (en) | 2007-10-25 | 2016-12-20 | Revalesio Corporation | Compositions and methods for treating inflammation |
| US20100008997A1 (en) | 2007-10-25 | 2010-01-14 | Revalesio Corporation | Compositions and methods for treating asthma and other lung disorders |
| US20100009008A1 (en) | 2007-10-25 | 2010-01-14 | Revalesio Corporation | Bacteriostatic or bacteriocidal compositions and methods |
| JP5586470B2 (ja) | 2007-10-25 | 2014-09-10 | リバルシオ コーポレイション | 静菌性または殺菌性組成物および方法 |
| US20090227018A1 (en) | 2007-10-25 | 2009-09-10 | Revalesio Corporation | Compositions and methods for modulating cellular membrane-mediated intracellular signal transduction |
| US20090263495A1 (en) | 2007-10-25 | 2009-10-22 | Revalesio Corporation | Bacteriostatic or bacteriocidal compositions and methods |
| WO2010062628A1 (en) | 2008-10-27 | 2010-06-03 | Revalesio Corporation | Compositions and methods for treating asthma and other lung disorders |
| US20100004189A1 (en) | 2007-10-25 | 2010-01-07 | Revalesio Corporation | Compositions and methods for treating cystic fibrosis |
| US20100310665A1 (en) | 2007-10-25 | 2010-12-09 | Revalesio Corporation | Bacteriostatic or bacteriocidal compositions and methods |
| US20100303918A1 (en) | 2007-10-25 | 2010-12-02 | Revalesio Corporation | Compositions and methods for treating asthma and other lung disorders |
| US20100303917A1 (en) | 2007-10-25 | 2010-12-02 | Revalesio Corporation | Compositions and methods for treating cystic fibrosis |
| BRPI0819175A2 (pt) | 2007-11-05 | 2015-05-05 | Bausch & Lomb | Composição farmacêutica oftálmica, e, método para proporcionar disponibilidade estendida de um componente farmacêutico em um ambiente ocular de um indivíduo, e, uso de pelo menos um componente farmacêutico, pelo menos um material imiscível em água e opcionalmente um composto modificador de viscosidade |
| US8114883B2 (en) | 2007-12-04 | 2012-02-14 | Landec Corporation | Polymer formulations for delivery of bioactive materials |
| MX364408B (es) | 2007-12-20 | 2019-04-25 | Univ Southern California | Aparatos y metodos para suministrar agentes terapeuticos. |
| US8414646B2 (en) | 2007-12-27 | 2013-04-09 | Forsight Labs, Llc | Intraocular, accommodating lens and methods of use |
| WO2009089409A2 (en) | 2008-01-10 | 2009-07-16 | Bausch & Lomb Incorporated | Intravitreal injection system having coaxial cannulae and use thereof |
| WO2009094466A2 (en) | 2008-01-22 | 2009-07-30 | University Of Florida Research Foundation, Inc. | Contact lenses for extended release of bioactive agents containing diffusion attenuators |
| US8201752B2 (en) | 2008-03-10 | 2012-06-19 | Vapore, Inc. | Low energy vaporization of liquids: apparatus and methods |
| TNSN08110A1 (en) | 2008-03-11 | 2009-07-14 | Rekik Raouf Dr | Drug delivery to the anterior and posterior segment of the eye from drops |
| WO2009117112A2 (en) | 2008-03-21 | 2009-09-24 | Novartis Ag | Powder dispersion apparatus, method of making and using the apparatus, components that can be used on the apparatus and other devices, and various active agents |
| CA2720067C (en) | 2008-03-31 | 2020-10-06 | Altea Therapeutics Corporation | Permeant delivery system and methods for use thereof |
| WO2010008424A2 (en) | 2008-04-04 | 2010-01-21 | Novartis Ag | Aerosolization device |
| US20090258069A1 (en) | 2008-04-15 | 2009-10-15 | John Burnier | Delivery of LFA-1 antagonists to the gastrointestinal system |
| EP2280676A2 (en) * | 2008-04-25 | 2011-02-09 | The Regents of the University of California | Device to store and inject corneal graft |
| CN104623741A (zh) | 2008-04-30 | 2015-05-20 | 马缇医疗股份有限公司 | 复合泪管植入物及相关方法 |
| WO2009134929A2 (en) | 2008-05-01 | 2009-11-05 | Revalesio Corporation | Compositions and methods for treating digestive disorders |
| US7846124B2 (en) | 2008-05-07 | 2010-12-07 | Becker Bruce B | Punctal anchor for lacrimal stent, introducer tool and method |
| US8348897B2 (en) | 2008-05-08 | 2013-01-08 | Minipumps, Llc | Implantable drug-delivery devices, and apparatus and methods for filling the devices |
| WO2010005617A2 (en) | 2008-07-11 | 2010-01-14 | Intellicyt | Multi-sample particle analyzer system and method for high throughput screening |
| CA2731435A1 (en) | 2008-07-21 | 2010-01-28 | Arstasis, Inc. | Devices, methods, and kits for forming tracts in tissue |
| US20100023033A1 (en) | 2008-07-25 | 2010-01-28 | Medtronic Vescular, Inc. | Hydrodynamic Thrombectomy Catheter |
| US20100022943A1 (en) | 2008-07-25 | 2010-01-28 | Medtronic Vascular, Inc. | Hydrodynamic Thrombectomy Catheter |
| WO2010021993A1 (en) | 2008-08-19 | 2010-02-25 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease |
| US8221353B2 (en) | 2008-10-21 | 2012-07-17 | KMG Pharma, Inc | Intravitreal injection device and system |
| US7678078B1 (en) | 2008-10-21 | 2010-03-16 | KMG Pharma LLC | Intravitreal injection device, system and method |
| DE102008054431B3 (de) | 2008-12-09 | 2010-06-17 | Pari Pharma Gmbh | Aerosoltherapievorrichtung |
| AU2009333100B2 (en) | 2009-01-02 | 2014-08-14 | Alcon Research, Ltd. | In-situ refillable ophthalmic implant |
| US8235932B2 (en) | 2009-01-09 | 2012-08-07 | Becker Bruce B | Side-by-side lacrimal intubation threader and method |
| US8545554B2 (en) | 2009-01-16 | 2013-10-01 | Allergan, Inc. | Intraocular injector |
| SG2014007389A (en) | 2009-01-29 | 2014-04-28 | Forsight Vision4 Inc | Posterior segment drug delivery |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| WO2010093945A2 (en) | 2009-02-13 | 2010-08-19 | Glaukos Corporation | Uveoscleral drug delivery implant and methods for implanting the same |
| US20110305751A1 (en) | 2009-02-20 | 2011-12-15 | To-Bbb Holding B.V. | Glutathione-based drug delivery system |
| US8287494B2 (en) | 2009-03-23 | 2012-10-16 | Colin Ma | Intravitreal injection devices and methods of injecting a substance into the vitreous chamber of the eye |
| WO2010126908A1 (en) | 2009-04-27 | 2010-11-04 | Revalesio Corporation | Compositions and methods for treating insulin resistance and diabetes mellitus |
| WO2010125416A1 (en) | 2009-04-27 | 2010-11-04 | Raouf Rekik | Drug delivery to the anterior and posterior segments of the eye |
| US8815292B2 (en) | 2009-04-27 | 2014-08-26 | Revalesio Corporation | Compositions and methods for treating insulin resistance and diabetes mellitus |
| CN102802541A (zh) | 2009-05-15 | 2012-11-28 | 阿尔斯塔西斯公司 | 在组织中形成管道的装置、方法和成套用具 |
| CA2979355C (en) | 2009-05-18 | 2023-02-21 | Dose Medical Corporation | Drug eluting ocular implant |
| ES2921527T3 (es) | 2009-06-03 | 2022-08-29 | Forsight Vision5 Inc | Administración de fármaco en segmento anterior |
| WO2011008897A2 (en) | 2009-07-14 | 2011-01-20 | Board Of Regents, The University Of Texas System | Methods for making controlled delivery devices having zero order kinetics |
| WO2011008986A2 (en) | 2009-07-15 | 2011-01-20 | California Institute Of Technology | A method applying hemodynamic forcing and klf2 to initiate the growth and development of cardiac valves |
| WO2011020049A1 (en) | 2009-08-14 | 2011-02-17 | Genentech, Inc. | Biological markers for monitoring patient response to vegf antagonists |
| US20120283316A1 (en) | 2009-09-01 | 2012-11-08 | Northwestern University | Delivery of Therapeutic Agents Using Oligonucleotide-Modified Nanoparticles As Carriers |
| CA2811959A1 (en) | 2009-09-21 | 2011-03-24 | Harvard Bioscience, Inc. | Methods and apparatus for introducing cells at a tissue site |
| US20120245505A1 (en) * | 2009-12-16 | 2012-09-27 | Robinson Michael R | Intracameral devices for sustained delivery |
| US20110238036A1 (en) | 2009-12-23 | 2011-09-29 | Psivida Us, Inc. | Sustained release delivery devices |
| WO2013022801A1 (en) | 2011-08-05 | 2013-02-14 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
| US8430853B2 (en) | 2010-02-05 | 2013-04-30 | Johnson & Johnson Vision Care, Inc. | Implantation instruments, system, and kit for punctal implants |
| JP5511530B2 (ja) * | 2010-06-10 | 2014-06-04 | Hoya株式会社 | 眼内レンズ挿入装置 |
| HRP20211909T1 (hr) | 2010-08-05 | 2022-03-18 | Forsight Vision4, Inc. | Uređaj za liječenja oka |
| US9033911B2 (en) | 2010-08-05 | 2015-05-19 | Forsight Vision4, Inc. | Injector apparatus and method for drug delivery |
| EP2600920A4 (en) | 2010-08-05 | 2017-10-04 | Forsight Vision4, Inc. | Subconjunctival implant for posterior segment drug delivery |
| CA2807537C (en) | 2010-08-05 | 2018-09-18 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
| US20140033800A1 (en) | 2010-11-11 | 2014-02-06 | Forsight Vision4, Inc. | Methods and apparatus to determine diffusion properties of porous structures for drug delivery |
| US20140031769A1 (en) | 2010-11-19 | 2014-01-30 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
| EP4249059B1 (en) | 2011-06-28 | 2025-07-30 | ForSight Vision4, Inc. | An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye |
| EP4643921A3 (en) | 2011-09-16 | 2026-01-07 | ForSight Vision4, Inc. | Fluid exchange apparatus |
| FR2980102B1 (fr) * | 2011-09-16 | 2014-10-31 | Medicontur Orvostechnikai Korlatolt Felelossegu Tarsasag | Dispositif pour injecter une lentille intraoculaire dans un œil |
| CA2857529A1 (en) * | 2011-12-02 | 2013-06-06 | Bioceptive, Inc. | Methods and apparatus for inserting a device or pharmaceutical into a uterus |
| US10010448B2 (en) | 2012-02-03 | 2018-07-03 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| ES2610198T3 (es) * | 2012-06-04 | 2017-04-26 | Alcon Pharmaceuticals Ltd. | Dispositivo de inserción de lente intraocular y método para descargar una lente intraocular desde un cartucho |
| AU2014236455B2 (en) | 2013-03-14 | 2018-07-12 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
| WO2014160884A1 (en) | 2013-03-28 | 2014-10-02 | Forsight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
| CN104994810B (zh) * | 2013-04-03 | 2018-03-02 | 诺华股份有限公司 | 自动化人工晶状体注入器装置 |
| US9987163B2 (en) * | 2013-04-16 | 2018-06-05 | Novartis Ag | Device for dispensing intraocular substances |
| WO2015085234A1 (en) | 2013-12-06 | 2015-06-11 | Forsight Vision4, Inc. | Implantable therapeutic devices |
| RU2695563C2 (ru) | 2014-07-15 | 2019-07-24 | Форсайт Вижн4, Инк. | Способ и устройство для доставки глазного имплантата |
| JP2017524034A (ja) | 2014-08-08 | 2017-08-24 | フォーサイト・ビジョン フォー・インコーポレーテッドForsight Vision4, Inc. | 受容体型チロシンキナーゼ阻害剤の安定で可溶な製剤およびその調製の方法 |
| KR20170106298A (ko) | 2014-11-10 | 2017-09-20 | 포사이트 비젼4, 인크. | 확장 가능한 약물 전달 장치 및 이용 방법 |
| EP3377009B1 (en) | 2015-11-20 | 2020-10-28 | ForSight Vision4, Inc. | Porous structures for extended release drug delivery devices |
| CN113017981B (zh) | 2016-04-05 | 2023-07-25 | 弗赛特影像4股份有限公司 | 药物递送装置 |
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