CN105228676A - 包括具有内联干燥药物组件的小瓶转接器的医疗装置 - Google Patents

包括具有内联干燥药物组件的小瓶转接器的医疗装置 Download PDF

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CN105228676A
CN105228676A CN201480026311.3A CN201480026311A CN105228676A CN 105228676 A CN105228676 A CN 105228676A CN 201480026311 A CN201480026311 A CN 201480026311A CN 105228676 A CN105228676 A CN 105228676A
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CN105228676B (zh
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休·扎卡里·马克斯
尼姆罗德·列弗
阿米尔·列弗
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    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
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    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
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    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing

Abstract

医疗装置，该医疗装置包括具有内联干燥药物组件(33)的小瓶转接器，内联干燥药物组件(33)与小瓶、无针注射器和载液一起使用，用于使得无针注射器填充有注射液用来向患者注射。内联干燥药物组件(33)包括用于储存干燥药物剂量的干燥药物储存构件(57)和均匀载液分布构件(58)，均匀载液分布构件(58)用于促进载液均匀接触干燥药物储存构件以形成来自干燥药物剂量的注射液。该内联干燥药物组件可包括分离的干燥药物储存构件和分离的均匀载液分布构件或用于药物储存和均匀载液分布的双重目的构件。该小瓶转接器可以通气式或非通气式形式被提供。

Description

包括具有内联干燥药物组件的小瓶转接器的医疗装置
技术领域
本发明涉及具有内联干燥药物组件的医疗装置，其包括与液体源一起使用的干燥药物剂量用于向患者肠道外投予。
背景技术
医学治疗通常涉及向人体肠道外投予液体药物。液体药物可呈溶液、悬浮剂等形式。一些药物试剂在干燥状态具有延长的储存期，在重构或再水化后仅仅具有短的储存期。
美国专利号6,520,932(Taylor)公开了内联药物递送包(35)，内联药物递送包(35)内联连接静脉注射(IV)管(intravenous(IV)line)并且允许稀释剂和待递送给患者的药物试剂的混合。该药物递送包包括具有试剂床(110)的外壳(37)，试剂床(110)由适合通过溶解和静脉滴注向患者投予的液体可溶的材料构成。该外壳包括入口径向鳍状物(65)，入口径向鳍状物(65)与来自入口端筛板(inletfrit)(80)的背压配合以促进稀释剂横跨药物递送包的整个横截面的均匀分布。当干燥的试剂被溶解时，内部药物床旁路机械装置(internaldrugbedbypassmechanism)被调整以分配旁路和药物床之间的稀释剂液流以获得适合于静脉投予的溶液浓度。
美国专利号6,951,613(Reif等)公开了基因接种疫苗装置以及为此形成注射液的方法。该装置包括注射器(2)和被连接到内联膜吸附器(5)上的套管(3)，内联膜吸附器(5)具有在其上被吸附的基因材料。该方法包括从膜吸附器上洗脱基因材料以形成含有基因材料的注射液。
美国专利申请公开号US2008/0294100(deCosta等)公开了用于向患者投予基质的药物装置。该deCosta药物装置类似于上述的Reif基因接种疫苗装置，不同之处在于它包括内联多孔膜，该内联多孔膜负载在水中可溶的玻璃质材料并且具有稳定在其上的比如疫苗的生物材料使得当生物材料需要投予时，洗脱液可以横穿膜，溶解玻璃质物并且使得物质通过液体被携带入患者。
Reif基因接种疫苗装置和deCosta药物装置是相对笨重并且在向患者注射注射液期间操作麻烦。再者，它们的含有向患者注射的干燥药物剂量的装置外壳必然以比通常的注射角度更大的角度向患者身体进行注射。
需要医疗装置，该医疗装置具有内联干燥药物组件用于容易向患者注射注射液。
发明内容
本发明针对的是包括具有内联干燥药物组件的小瓶转接器的医疗装置，该内联干燥药物组件具有干燥药物剂量用于与无针注射器和小瓶一起使用，用于使得无针注射器填充有由干燥的药物剂量组成的注射液用于向患者投予。该医疗装置优选地与初始地空无针注射器和初始地填充有液态载剂(liquidcarrier)的小瓶一起使用。或者，该医疗装置可用于与初始地预填充有液态载剂的注射器和初始地空瓶一起使用。该液态载剂可以仅仅是稀释剂，或者可包括活性成分。
该小瓶转接器具有类似于市场上可获得的通气式或非通气式小瓶转接器的构造，除了内联干燥药物组件之外。该内联干燥药物组件包括用于储存干燥药物剂量的干燥药物储存构件和均匀载液分布构件，该均匀载液分布构件用于促进该载液均匀接触干燥药物储存构件以形成注射液。该干燥药物储存构件和该均匀载液分布构件可以是两个分离的构件。或者，该两个构件可以单一的双重目的构件(singledualpurposecomponent)被组合。
该内联干燥药物组件可利用数个市场上可获得的技术中任何一种用于实现长期储存干燥药物剂量用来随后接触载液形成注射液。合适的市场上可获得的技术尤其在背景技术中承认的现有技术参考文献中被讨论了。不同的技术尤其包括使载液流过多孔基质以溶解或带走干燥药物剂量，使载液在基质表面上流动以溶解或带走干燥药物剂量等。
本发明的医疗装置与初始地空无针注射器和初始地填充的小瓶一起使用涉及单一吸入。或者，本发明的医疗装置与初始地填充的注射器和初始地空瓶一起使用需要从注射器初始地注射载液到小瓶并且随后地从小瓶吸入到注射器。至于完全使用干燥药物剂量，前者使用需要较少的时间而后者使用能提供较大的确定性。
本发明的医疗装置对准备无针注射器用来向患者注射注射液提供了方便的低成本方案。本发明的医疗装置尤其适用于与所谓的热稳定的药物和试剂一起使用，该热稳定的药物和试剂在周围环境温度下具有相对长的储存期，从而无需冷藏。合适的药物和试剂尤其包括疫苗等。
附图说明
为了理解本发明并且理解在实践中如何实施它，参考附图，仅仅借助于非限制性实施例，优选的实施例将被描述，其中相同的部分做了同样的编号，其中：
图1是初始地空无针注射器、小瓶和根据本发明第一实施例的用于使初始地空的无针注射器填充有注射液的通气式医疗装置的图示；
图2是图1中医疗装置的底部透视图；
图3是图1中医疗装置的侧视图；
图4是图1中医疗装置沿图3中A-A线的纵向截面图；
图5是图1中医疗装置的分解图；
图6是图1中医疗装置的均匀载液分布构件的底部透视图；
图7A显示了在将载液从小瓶吸入到无针注射器之前，初始地空无针注射器、图1医疗装置和小瓶的倒置的组合件；
图7B显示了载液从小瓶部分吸入到无针注射器之后倒置的组合件；
图7C显示了填充有注射液的无针注射器用于向患者投予的倒置的组合件；
图8是图7B的组合件的环形部分的近距离纵向截面图，显示了在吸入期间，载液从小瓶流向注射器；
图9是根据本发明第二实施例的通气式医疗装置的分解图；以及
图10是图9医疗装置的均匀载液分布构件的底部透视图。
附图的详细描述
图1显示了空无针注射器10、小瓶20和通气式医疗装置30，用于使得无针注射器10填充有注射液用于向患者投予。注射器10包括具有柱塞杆12和注射器端13的活塞筒11。小瓶20包括由小瓶瓶塞22密封的小瓶瓶体21。小瓶瓶体21通常包括用于固定小瓶瓶体21上的小瓶瓶塞22的铝密封条23。小瓶瓶体21具有含有载液26的小瓶内部24。载液26可以仅仅是稀释剂。或者，载液26可包括活性成分。
图1到6显示了医疗装置30具有纵向的装置中心线31并且包括具有内联干燥药物组件33的小瓶转接器32。小瓶转接器32包括裙34，裙34具有横向的顶部裙壁36和向下悬垂的弯曲部件37用于伸缩地安装到小瓶20上。顶部裙壁36与中心的裙毂(centralskirthub)38一起形成，裙毂与纵向的装置轴31同轴，具有6个平均间隔的从其向外延伸的径向肋状物39。中心的裙毂38同与纵向装置轴31同轴的液体转移端口41和相对于纵向装置轴31偏移的通气端口42一起形成。
小瓶转接器32包括顶盖43，顶盖43具有中心的直立的母连接头44，其与纵向的装置中心线31同轴，用于与注射器端13的密封连接。注射器端13优选是公鲁尔锁接头，中心的直立的母连接头44是母鲁尔锁接头用于螺纹安装无针注射器10到医疗装置30上。或者，注射器端13与母连接头44可以与其它连接头一起形成。
小瓶转接器32包括向下悬垂的穿刺套管46，其与纵向的装置31同轴用于当伸缩地安装医疗装置30到小瓶20上时刺穿小瓶瓶塞22用于与小瓶内部24的流体连通。套管46包括与液体转移端口41流体连通的液体转移腔47和与通气端口42流体连通的通气腔48。
小瓶转接器32包括用于在顶盖43和顶部裙壁36之间部署的过滤器盖49。过滤器盖49包住放置在径向肋状物39上的空气过滤器51。空气过滤器51具有与纵向的装置轴31同轴的中心的空气过滤器孔52。过滤器盖49包括与纵向的装置轴31同轴的中心的过滤器盖孔53和与多个通气孔56一起形成的外围的过滤器盖边缘54。
内联干燥药物组件33被内联地设置在中心的直立的母连接头44和穿刺套管46，具体地说液体转移端口41，之间。内联干燥药物组件33包括干燥药物储存构件57，其接近直立的母连接头44并且远离穿刺套管46。内联干燥药物组件33进一步包括均匀载液分布构件58，其接近穿刺套管46并且远离直立的母连接头44。
干燥药物储存构件57优选形成为圆盘样的基质，其由广泛的合适的生物相容的惰性多孔材料构成，使得载液26从中流动。合适的材料尤其包括玻璃纤维、塑料纤维等。干燥药物储存构件57被提供有干燥药物剂量59用于向患者投予。干燥药物剂量59可呈极细的颗粒形式等，用于当携带载液26通过干燥药物储存构件57时实现注射液的重构。
均匀载液分布构件58优选地形成为圆盘样部件，其具有朝向直立的母连接头44的均匀载液分布构件顶侧58A、朝向穿刺套管46的均匀载液分布构件下侧58B和均匀载液分布构件外围边缘61。均匀载剂分布构件下侧58B与一系列径向的沟槽62一起形成，各自终止在均匀载液分布构件外围边缘61中的开口(cutout)63中，用于实现从均匀载液分布构件下侧58B到均匀载液分布构件顶侧58A的流体连通。
现在参考图7A到7C和图8，描述了医疗装置30的使用，其用于准备具有用于向个体注射的注射液的无针注射器10，其中图8是图7B中A所示的圆形区域的放大图。
图7A显示了使用者伸缩地安装医疗装置30到小瓶20上以刺穿小瓶瓶塞22。使用者连接无针注射器10到母连接头44上。使用者倒置组合件使得小瓶20在无针注射器10以上并且开始从小瓶20吸入载液26到无针注射器10中。
图7B和图8显示载液26从小瓶20流到初始地空无针注射器10，如下所示：载液26沿着液体转移腔47向下流到均匀载液分布构件下侧58B。载液26沿着径向的沟槽62从均匀载液分布构件下侧58B的中心向外径向地流动到均匀载液分布构件外围边缘61。
载液26向下流动通过开口63并且接着径向地向内通过多孔的干燥药物储存构件57以随其带走干燥药物剂量59以形成注射液64。在载液26从小瓶20吸入到注射器10期间，空气被吸进通过通气孔56、空气过滤器51和通气腔48进入小瓶20中，如载液26中的气泡所示。
图7C显示了填充有注射液64的注射器10在从母连接头44分离并且连接针头之后，准备用于向个体注射。
图9显示了构造和操作上类似于通气式医疗装置30的通气式医疗装置70，因此，相同的部件被做了同样的编号。后者70不同于前者30之处在于它的内联干燥药物组件33包括单一的双重目的构件71，其充当干燥药物剂量储存构件和均匀载液分布构件。该双重目的构件71具有类似于均匀载液分布构件58的构造之处在于它包括朝向母连接头44的均匀载液分布构件顶侧71A、朝向穿刺套管46的均匀载液分布构件下侧71B和均匀载液分布构件外围边缘72。均匀载液分布构件顶侧71A具有干燥药物剂量涂层73，其构成干燥药物剂量储存构件。均匀载剂分布构件下侧71B由一系列径向的沟槽62构成，各自终止在均匀载液分布构件外围边缘72中的开口63处用于实现从均匀载液分布构件下侧71B到均匀载液分布构件顶侧71A的流体连通。
虽然本发明已经描述了有限数目的实施例，本发明的许多变化，修改以及其它应用能在本申请权利要求书的范围内被做出。

Claims (4)

1.医疗装置，所述医疗装置与无针注射器、小瓶和载液一起使用，用于使得无针注射器填充有注射液用来向患者注射，所述无针注射器具有公连接头，所述小瓶具有小瓶瓶塞和小瓶内部，所述医疗装置具有纵向的装置中心线并且包括：
(a)小瓶转接器，所述小瓶转接器具有裙、穿刺套管和中心的直立的公连接头，所述裙具有用于伸缩地安装到小瓶上的向下悬垂的弯曲部件，所述穿刺套管用于当所述的伸缩地安装时刺穿瓶塞用来与小瓶内部流体连通，所述中心的直立的公连接头与所述穿刺套管流体连通并且用来连接到公连接头；以及
(b)内联干燥药物组件，所述内联干燥药物组件在所述母连接头和所述穿刺套管之间被内联地设置，所述内联干燥药物组件包括用于储存干燥药物剂量的干燥药物储存构件和均匀载液分布构件，所述均匀载液分布构件用于当从小瓶吸入载液到无针注射器以形成注射液时，促进所述载液均匀接触所述干燥药物储存构件。
2.根据权利要求1所述的装置，其中所述内联干燥药物组件包括用于储存所述干燥药物剂量的分离的干燥药物储存构件和用于促进所述均匀接触的分离的均匀载液分布构件。
3.根据权利要求1所述的装置，其中所述内联干燥药物组件包括用于储存所述干燥药物剂量和促进所述均匀接触的双重目的构件。
4.根据权利要求1到3中任一项所述的装置，其中所述均匀载液构件包括朝向所述母连接头的均匀载液构件顶侧、朝向所述穿刺套管的均匀载液分布构件下侧和均匀载液分布构件外围边缘，
所述均匀载液分布构件下侧具有多个径向的沟槽，各自终止在所述均匀载液分布构件外围边缘中的开口中，从而当抽吸无针注射器以将液体内容物从小瓶抽取到无针注射器时，使得载液从所述均匀载液分布构件下侧流向所述均匀载液分布构件顶侧。
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109152699A (zh) * 2016-05-24 2019-01-04 西部制药服务以色列有限公司 包括相同的成对的小瓶转接器的双瓶转接器组合件
CN109432554A (zh) * 2018-11-19 2019-03-08 北京快舒尔医疗技术有限公司 无针注射器的注射头、注射头组件和无针注射器
CN110996877A (zh) * 2017-08-10 2020-04-10 巴克斯特国际公司 以适度剂量供给药物的重构装置、系统和方法
WO2022047962A1 (zh) * 2020-09-04 2022-03-10 汪祥海 一种液体注入器转接头

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7547300B2 (en) 2006-04-12 2009-06-16 Icu Medical, Inc. Vial adaptor for regulating pressure
WO2010022095A1 (en) 2008-08-20 2010-02-25 Icu Medical, Inc. Anti-reflux vial adaptors
EP2459146B1 (en) 2009-07-29 2020-04-29 ICU Medical, Inc. Fluid transfer methods
ES2934668T3 (es) 2011-08-18 2023-02-23 Icu Medical Inc Adaptadores de vial de regulación de presión
AU2012324021A1 (en) 2011-12-22 2013-07-11 Icu Medical, Inc. Fluid transfer devices and methods of use
WO2013106757A1 (en) 2012-01-13 2013-07-18 Icu Medical, Inc. Pressure-regulating vial adaptors and methods
AU2013204180B2 (en) 2012-03-22 2016-07-21 Icu Medical, Inc. Pressure-regulating vial adaptors
ES2739291T3 (es) 2013-01-23 2020-01-30 Icu Medical Inc Adaptadores de vial de regulación de presión
US9089475B2 (en) 2013-01-23 2015-07-28 Icu Medical, Inc. Pressure-regulating vial adaptors
JP6617101B2 (ja) 2013-07-19 2019-12-04 アイシーユー メディカル インコーポレイテッド 圧力調整流体移注システムおよび方法
WO2015077184A1 (en) 2013-11-25 2015-05-28 Icu Medical, Inc. Methods and system for filling iv bags with therapeutic fluid
AU2015277135B2 (en) 2014-06-20 2020-02-20 Icu Medical, Inc. Pressure-regulating vial adaptors
US10149969B2 (en) * 2014-09-25 2018-12-11 L'oréal Skin treatment appliance with changeable workpiece
US10039913B2 (en) * 2015-07-30 2018-08-07 Carefusion 303, Inc. Tamper-resistant cap
US11458071B2 (en) * 2017-05-11 2022-10-04 Scalpal Llc Torque enhancer device for grasping and tooling, and assemblies and uses thereof
AU2016365335B2 (en) 2015-12-04 2021-10-21 Icu Medical, Inc. Systems methods and components for transferring medical fluids
CA3012733C (en) 2016-01-29 2023-09-12 Icu Medical, Inc. Pressure-regulating vial adaptors
CA3015885A1 (en) 2016-02-24 2017-08-31 Neomed, Inc. Fluid transfer connector
DE102016110569B3 (de) 2016-06-08 2017-10-26 Sfm Medical Devices Gmbh Adapter
USD851745S1 (en) 2016-07-19 2019-06-18 Icu Medical, Inc. Medical fluid transfer system
EP3487468A4 (en) 2016-07-25 2020-03-25 ICU Medical, Inc. SYSTEMS, METHODS AND COMPONENTS FOR TRAPPING AIR BUBBLES IN MODULES AND MEDICAL FLUID TRANSFER SYSTEMS.
AU2017335746A1 (en) 2016-09-30 2019-04-11 Icu Medical, Inc. Pressure-regulating vial access devices and methods
CN111867545B (zh) 2017-12-03 2021-11-23 西部制药服务有限公司(以色列) 与输液容器和离散注射瓶一起使用的带伸缩瓶子适配器的液体传输装置
US11224555B2 (en) 2018-04-23 2022-01-18 Hospira, Inc. Access and vapor containment system for a drug vial and method of making and using same
CN112105328B (zh) * 2018-05-17 2024-03-01 贝克顿迪金森法国公司 用于将医用注射设备连接到容器的连接器
USD923812S1 (en) 2019-01-16 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
JP1648075S (zh) * 2019-01-17 2019-12-16
PT3917486T (pt) 2019-01-31 2023-05-08 West Pharma Services Il Ltd Dispositivo de transferência de líquido
EP4360670A2 (en) 2019-04-30 2024-05-01 West Pharma Services IL, Ltd Liquid transfer device with dual lumen iv spike
US11590057B2 (en) 2020-04-03 2023-02-28 Icu Medical, Inc. Systems, methods, and components for transferring medical fluids
USD956958S1 (en) 2020-07-13 2022-07-05 West Pharma. Services IL, Ltd. Liquid transfer device
US11674614B2 (en) 2020-10-09 2023-06-13 Icu Medical, Inc. Fluid transfer device and method of use for same
WO2022146949A1 (en) * 2020-12-28 2022-07-07 Typenex Medical, Llc Sampling device
CN113320837B (zh) * 2021-06-09 2022-07-26 南通智宏生物科技有限公司 一种具有分流功能的药剂瓶
USD1010112S1 (en) 2021-07-03 2024-01-02 KAIRISH INNOTECH Private Ltd. Vial adapter with valve
EP4115918A1 (en) * 2021-07-06 2023-01-11 Prof. Dr. Dr. Prantl, Dr. Baringer, Dr. Felthaus Und Eigenberger GbR (REG-2) Syringe system for processing a fluid
WO2024076590A2 (en) 2022-10-03 2024-04-11 West Pharmaceutical Services, Inc. Methods and adapters for mixing pharmaceutical complexes
WO2024077016A2 (en) 2022-10-03 2024-04-11 West Pharmaceutical Services, Inc. Microfluidic mixing and/or separater

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871463A (en) * 1988-08-23 1989-10-03 Sepratech Vertical reaction vessel
US20020193733A1 (en) * 1999-11-19 2002-12-19 Taylor Michael A. In-line iv drug delivery pack with controllable dilution
US20030068354A1 (en) * 2001-10-05 2003-04-10 Oscar-Werner Reif Genetic vaccination device and process for forming an injection therefor
CN1744871A (zh) * 2003-02-05 2006-03-08 阿卡多福塔公司 用于临时制备单次使用量的无菌流体的装置和方法
JP2006061421A (ja) * 2004-08-26 2006-03-09 Bio Media Co Ltd 薬剤収容ユニット
WO2007101772A1 (en) * 2006-03-07 2007-09-13 Novo Nordisk A/S A drug mixing device
CN101378727A (zh) * 2005-11-21 2009-03-04 剑桥生物稳定性有限公司 用于向患者供给药物的药用装置
WO2012004784A1 (en) * 2010-07-04 2012-01-12 Medimop Medical Projects Ltd Vial adapter with syringe stabilizer
CN102711712A (zh) * 2010-02-24 2012-10-03 麦迪麦珀医疗工程有限公司 具有通风布置的流体转移组合件

Family Cites Families (691)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US300060A (en) 1884-06-10 Isaac v
US62333A (en) 1867-02-26 Henry holl
US254444A (en) 1882-02-28 Chaeles w
US1021681A (en) 1911-02-13 1912-03-26 John F Jennings Valve for corrosive liquids.
US1704817A (en) 1928-01-17 1929-03-12 Okadee Company Locomotive-cylinder cock
US1930944A (en) 1932-12-21 1933-10-17 Jr William L Schmitz Measuring dispenser
US2247975A (en) 1940-04-16 1941-07-01 Tinnerman Products Inc Fastening installation and fastener therefor
US2326490A (en) 1942-06-13 1943-08-10 Harold N Perelson Fluid dispenser
US2560162A (en) 1950-02-10 1951-07-10 Becton Dickinson Co Needle structure
US2748769A (en) 1953-02-24 1956-06-05 Huber Jennie Hypodermic needle
US2830587A (en) 1954-02-01 1958-04-15 Everett Samuel James Hypodermic needles
US3059643A (en) 1954-12-10 1962-10-23 Baxter Laboratories Inc Pumping apparatus
US2931668A (en) 1956-04-30 1960-04-05 Bastian Blessing Co Coupling
US2968497A (en) 1958-02-05 1961-01-17 Avro Aircraft Ltd Self-sealing coupling
US3225763A (en) 1962-06-18 1965-12-28 Chesebrough Ponds Medicinal injector
US3277893A (en) 1964-01-31 1966-10-11 Becton Dickinson Co Hypodermic projectile with barb in the cannula bevel
US3308822A (en) 1964-04-02 1967-03-14 Loretta Fontano Hypodermic needle
DE1945279U (de) 1966-07-02 1966-09-01 Gruenenthal Chemie Hilfsgeraet zur herstellung von sterilen loesungen.
FR2029242A5 (en) 1969-01-21 1970-10-16 Alriq Christian Self-perforable plug for bacteriological - culture tubes
DE1913926A1 (de) 1969-03-19 1970-09-24 Hoechst Ag Zweikammerspritze
US3757981A (en) 1969-11-24 1973-09-11 Harris R Valves and valve needle syringes
US3618637A (en) 1970-02-04 1971-11-09 Deseret Pharma Rotary mixing valve
US3788524A (en) 1971-12-22 1974-01-29 Cutter Lab Additive container
US3826261A (en) 1971-12-27 1974-07-30 Upjohn Co Vial and syringe assembly
US3822700A (en) 1973-03-16 1974-07-09 M Pennington Intravenous solution dispenser
US4109670A (en) 1973-05-16 1978-08-29 Slagel Roger D Combination check flow control and selector valve
US3872992A (en) 1973-08-06 1975-03-25 Pharmaco Inc Medicament vial stopper piercing and needle positioning device
US3885607A (en) 1973-11-16 1975-05-27 Richard I Peltier Device for providing fluid communication between two sealed vessels
FR2268707B1 (zh) 1974-04-26 1976-12-17 Becton Dickinson France
US3977555A (en) 1974-05-07 1976-08-31 Pharmaco, Inc. Protective safety cap for medicament vial
US3938520A (en) 1974-06-10 1976-02-17 Abbott Laboratories Transfer unit having a dual channel transfer member
US3957052A (en) 1974-09-13 1976-05-18 Medical Development Corporation Pumping-syringe
US3993063A (en) 1975-06-16 1976-11-23 Union Carbide Corporation Protective shielding assembly for use in loading a hypodermic syringe with radioactive material
US4051852A (en) 1975-06-26 1977-10-04 The Kendall Company Aspirating device
US4020839A (en) 1976-02-26 1977-05-03 Parke, Davis & Company Medicament-dispensing package
USD247975S (en) 1976-07-30 1978-05-23 Luther Ronald B Catheterization needle
US4210173A (en) 1976-12-06 1980-07-01 American Hospital Supply Corporation Syringe pumping system with valves
USD248568S (en) 1976-12-13 1978-07-18 Aaron Ismach Animal intradermal nozzle for jet injection device
US4121585A (en) 1977-01-24 1978-10-24 Becker Jr Karl E Anti backflow injection device
DE2714094C3 (de) 1977-03-30 1980-04-17 Bayer Ag, 5090 Leverkusen Vorrichtung zur Bestimmung des Wassergehaltes von isotropen Materialien mit Hilfe der Mikrowellenabsorption
US4187848A (en) 1977-07-18 1980-02-12 The Kendall Company Adapter assembly
USD254444S (en) 1977-09-01 1980-03-11 Levine Robert A Blood sampling needle
US4161178A (en) 1977-12-08 1979-07-17 Abbott Laboratories Additive transfer device
US4203443A (en) 1977-12-08 1980-05-20 Abbott Laboratories Additive transfer unit with interlocking means
USD257286S (en) 1978-03-06 1980-10-07 Tronomed International, Inc. Medical valve
US4314586A (en) 1978-08-30 1982-02-09 Tronomed International, Inc. Disposable valve
US4639019A (en) 1979-06-04 1987-01-27 Baxter Travenol Laboratories, Inc. Luer connection
US4312349A (en) 1979-07-23 1982-01-26 Cohen Milton J Filter device for injectable fluid
US4296786A (en) 1979-09-28 1981-10-27 The West Company Transfer device for use in mixing a primary solution and a secondary or additive substance
US4253501A (en) 1979-11-09 1981-03-03 Ims Limited Transfer system
US4303067A (en) 1980-01-21 1981-12-01 American Hospital Supply Corporation Medical liquid bag having an improved additive port
US4328802A (en) 1980-05-14 1982-05-11 Survival Technology, Inc. Wet dry syringe package
US4376634A (en) 1980-05-30 1983-03-15 Mallinckrodt, Inc. Assay kit having syringe, dilution device and reagents within sealed container
USD267199S (en) 1980-07-17 1982-12-07 Abbott Laboratories Vial and solution container connecting device
USD268871S (en) 1980-09-18 1983-05-03 Alva Medical, Inc. Medical tubing hub for catheters or the like
USD270282S (en) 1980-10-09 1983-08-23 Abbott Laboratories Catheter insertion adapter
US4335717A (en) 1980-10-10 1982-06-22 Abbott Laboratories I.V. Administration set with retrograde volume
USD271421S (en) 1981-06-12 1983-11-15 Fetterman James W Medical valve
US4434823A (en) 1981-06-29 1984-03-06 American Hospital Supply Corporation Liquid transfer device
US4493348A (en) 1981-06-29 1985-01-15 Pur/Acc Corporation Method and apparatus for orally dispensing liquid medication
US4465471A (en) 1981-08-26 1984-08-14 Eli Lilly And Company Intravenous administration system for dry medicine
US4392850A (en) 1981-11-23 1983-07-12 Abbott Laboratories In-line transfer unit
US4410321A (en) 1982-04-06 1983-10-18 Baxter Travenol Laboratories, Inc. Closed drug delivery system
US4458733A (en) 1982-04-06 1984-07-10 Baxter Travenol Laboratories, Inc. Mixing apparatus
US4475915A (en) 1982-05-07 1984-10-09 Sloane Glenn L Holder for a syringe and an ampoule
US4588396A (en) 1982-10-22 1986-05-13 Stroebel Maurice G Apparatus for gravity feed of liquid under constant hydrostatic pressure
USD280018S (en) 1982-10-25 1985-08-06 Commonwealth Industries Syringe loading guide
US4507113A (en) 1982-11-22 1985-03-26 Derata Corporation Hypodermic jet injector
US4752292A (en) 1983-01-24 1988-06-21 Icu Medical, Inc. Medical connector
US5688254A (en) 1983-01-24 1997-11-18 Icu Medical, Inc. Medical connector
US4505709A (en) 1983-02-22 1985-03-19 Froning Edward C Liquid transfer device
US4676530A (en) 1983-04-07 1987-06-30 Warner-Lambert Company Coupling assembly for use in fluid flow systems
US4778447A (en) 1983-05-20 1988-10-18 Travenol European Research & Development Center Connectors
EP0126718A3 (en) 1983-05-20 1985-10-23 Bengt Gustavsson A device for transferring a substance from one vessel to another and further to the intended application
JPS6026391U (ja) 1983-07-30 1985-02-22 株式会社ハーマン 管接続具
US4532969A (en) 1983-09-21 1985-08-06 Kwaan Hau C Fluid withdrawal and instillation device
US4573993A (en) 1983-09-29 1986-03-04 Instafil, Inc. Fluid transfer apparatus
USD284603S (en) 1983-11-25 1986-07-08 Loignon Edward G Syphon fitting
US4743243A (en) 1984-01-03 1988-05-10 Vaillancourt Vincent L Needle with vent filter assembly
IT1173370B (it) 1984-02-24 1987-06-24 Erba Farmitalia Dispositivo di sicurezza per collegare una siringa alla imboccatura di un flacone contenente un farmaco o di un tubicino per l'erogazione del farmaco della siringa
US4585446A (en) 1984-03-16 1986-04-29 Joseph Kempf Dialysis needle
US4581014A (en) 1984-04-03 1986-04-08 Ivac Corporation Fluid infusion system
US5088996A (en) 1984-04-16 1992-02-18 Kopfer Rudolph J Anti-aerosoling drug reconstitution device
US4697622A (en) 1984-06-01 1987-10-06 Parker Hannifin Corporation Passive filling device
US4588403A (en) 1984-06-01 1986-05-13 American Hospital Supply Corporation Vented syringe adapter assembly
US4604093A (en) 1984-06-12 1986-08-05 I-Flow Corporation Apparatus and method for administering multiple fluid infusions
US5113904A (en) 1984-07-13 1992-05-19 Aslanian Jerry L Flow control device for administration of intravenous fluids
US4607671A (en) 1984-08-21 1986-08-26 Baxter Travenol Laboratories, Inc. Reconstitution device
JPS6168045A (ja) 1984-09-10 1986-04-08 テルモ株式会社 医療用活栓
US4759756A (en) 1984-09-14 1988-07-26 Baxter Travenol Laboratories, Inc. Reconstitution device
US4614437A (en) 1984-11-02 1986-09-30 Dougherty Brothers Company Mixing container and adapter
USD300060S (en) 1985-02-25 1989-02-28 William Cook Europe A/S Biopsy cannula
SE8501656D0 (sv) 1985-04-03 1985-04-03 Mediplast Ab Overforingsanordning
US4721133A (en) 1985-09-26 1988-01-26 Alcon Laboratories, Inc. Multiple use valving device
US4675020A (en) 1985-10-09 1987-06-23 Kendall Mcgaw Laboratories, Inc. Connector
US4667927A (en) 1985-11-08 1987-05-26 Rao Medical Devices, Inc. Liquid flow metering device
DE3600496A1 (de) 1986-01-10 1987-07-16 Josef Magasi Punktionskanuele, deren griff sowie verfahren zu deren herstellung
US4865592A (en) 1986-02-20 1989-09-12 Becton, Dickinson And Company Container and needle assembly
US4834152A (en) 1986-02-27 1989-05-30 Intelligent Medicine, Inc. Storage receptacle sealing and transfer apparatus
US4735608A (en) 1986-05-14 1988-04-05 Del F. Kahan Apparatus for storing and reconstituting antibiotics with intravenous fluids
US5049129A (en) 1986-05-29 1991-09-17 Zdeb Brian D Adapter for passive drug delivery system
USD303013S (en) 1986-06-19 1989-08-22 Pacesetter Infusion, Ltd. Female luer connector
SE461765B (sv) 1986-07-10 1990-03-26 Haessle Ab Anordning foer frisaettning av substans
IT1201801B (it) 1986-08-04 1989-02-02 Pietro Cosmai Caricatore miscelatore per iniettori transcutanei
IE60235B1 (en) 1986-09-18 1994-06-15 Kabi Pharmacia Ab "Connector and disposable assembly utilising said connector"
US4743229A (en) 1986-09-29 1988-05-10 Collagen Corporation Collagen/mineral mixing device and method
US4683975A (en) 1986-09-30 1987-08-04 General Motors Corporation Vehicle power window control
US4797898A (en) 1986-11-21 1989-01-10 Racal Data Communications Inc. Method and apparatus for equalization of data transmission system
US4832690A (en) * 1987-01-23 1989-05-23 Baxter International Inc. Needle-pierceable cartridge for drug delivery
US4729401A (en) 1987-01-29 1988-03-08 Burron Medical Inc. Aspiration assembly having dual co-axial check valves
US5041105A (en) 1987-03-03 1991-08-20 Sherwood Medical Company Vented spike connection component
US4787898A (en) 1987-05-12 1988-11-29 Burron Medical Inc. Vented needle with sideport
US4758235A (en) 1987-05-26 1988-07-19 Tu Ho C Cardiopulmonary resuscitation medication assembly
AU101237S (en) 1987-06-18 1988-09-08 Ab Astra Transfer cannula
US5178607A (en) 1987-07-31 1993-01-12 Lynn Lawrence A Blood aspiration assembly septum and blunt needle aspirator
IT211830Z2 (it) 1987-09-22 1989-05-25 Farmitalia Carl Erba S P A Dispositivo di sicurezza perl'introduzione ed il prelievo di liquidi in e da flaconi di farmaci e simili.
US4804366A (en) 1987-10-29 1989-02-14 Baxter International Inc. Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system
USD314050S (en) 1987-11-27 1991-01-22 Terumo Kabushiki Kaisha Medical connector
US5211638A (en) 1988-01-25 1993-05-18 Baxter International Inc. Pre-slit injection site
DE3804429A1 (de) 1988-02-12 1989-08-24 Schleicher & Schuell Gmbh Einmalfilter
US4932944A (en) 1988-03-09 1990-06-12 The University Of Virginia Alumni Patents Foundation Intravenous port injection and connector system
US4857062A (en) 1988-03-09 1989-08-15 Medical Parameters, Inc. Catheter introducer valve
US4931040A (en) 1988-04-13 1990-06-05 Habley Medical Technology Safety syringe having a combination needle cannula and articulating hub for retracting said cannula into a medication carpule
US4898209A (en) 1988-09-27 1990-02-06 Baxter International Inc. Sliding reconstitution device with seal
US5122124A (en) 1988-12-14 1992-06-16 Patco Ventures Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US6344031B1 (en) 1989-03-22 2002-02-05 Laurel A. Novacek Safety syringe needle device with interchangeable and retractable needle platform
US5301685A (en) 1989-01-10 1994-04-12 Guirguis Raouf A Method and apparatus for obtaining a cytology monolayer
US5035686A (en) 1989-01-27 1991-07-30 C. R. Bard, Inc. Catheter exchange system with detachable luer fitting
USD328788S (en) 1989-05-01 1992-08-18 Terumo Kabushiki Kaisha Connector for catheter
US5135492A (en) 1989-06-26 1992-08-04 University Of Florida Arterial/venous fluid transfer system
USD341420S (en) 1989-07-14 1993-11-16 Ivac Corporation Combined universal spike and drip chamber
US4967797A (en) 1989-08-16 1990-11-06 Manska Wayne E Tap valve
US5053015A (en) 1989-08-30 1991-10-01 The Kendall Company Locking catheter adapter
US4997430A (en) 1989-09-06 1991-03-05 Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En Infusievloeistoffen B.V. Method of and apparatus for administering medicament to a patient
US5578015A (en) 1989-09-18 1996-11-26 Robb Pascal Patent Limited Safety syringe incorporating automatic needle holder release
CA2048601A1 (fr) 1990-01-08 1991-07-09 Gabriel Meyer Flacon de stockage et de transfert a double compartiment
US5304163A (en) 1990-01-29 1994-04-19 Baxter International Inc. Integral reconstitution device
US5125915A (en) 1990-03-02 1992-06-30 Cardiopulmonics, Inc. Locking y-connector for selective attachment to exterior of medical tubing
US5061248A (en) 1990-04-04 1991-10-29 Sacco John J Injection port safety shield
USRE38996E1 (en) 1990-04-20 2006-02-28 Becton, Dickinson And Company Needle tip cover
US5006114A (en) 1990-04-20 1991-04-09 Rogers Bobby E Medical valve assembly
US5104387A (en) 1990-05-25 1992-04-14 St. Jude Medical, Inc. Bi-planar fluid control valve
US5045066A (en) 1990-06-07 1991-09-03 Smith & Nephew, Inc. Dental needle with stick resistant protective sleeve
US5203775A (en) 1990-09-18 1993-04-20 Medex, Inc. Needleless connector sample site
US5515871A (en) 1990-09-28 1996-05-14 Sulzer Brothers Ltd. Hollow needle for medical use and a laser method for manufacturing
US5125908A (en) 1990-10-19 1992-06-30 Cohen Milton J Hypodermic syringe with protective holder
US5201717A (en) 1990-12-05 1993-04-13 Philip Wyatt Safety enclosure
US5232029A (en) 1990-12-06 1993-08-03 Abbott Laboratories Additive device for vial
JP3066611B2 (ja) 1991-04-30 2000-07-17 武田薬品工業株式会社 個別密封容器に収容した２種薬剤の無菌保持混合装置
US5183469A (en) 1991-05-10 1993-02-02 Becton, Dickinson And Company Device for the removal and replacement of a needle shield
DE4122221A1 (de) 1991-07-04 1993-03-18 Axel Von Brand Transfer- und entnahmespike
DE4122476A1 (de) 1991-07-06 1993-01-07 Leopold Pharma Gmbh Verfahren und vorrichtung zum ueberleiten von zwei oder mehr sterilen fluessigkeiten im geschlossenen system
US5288290A (en) 1991-09-25 1994-02-22 Alcon Surgical, Inc. Multi-ported valve assembly
US5242432A (en) 1991-09-26 1993-09-07 Ivac Needleless adapter
WO1993010001A1 (en) 1991-11-21 1993-05-27 Gds Technology, Inc. Fluid transfer device
US5171230A (en) 1991-11-29 1992-12-15 Medex, Inc. Fast flush catheter valve
US5304165A (en) 1991-12-09 1994-04-19 Habley Medical Technology Corporation Syringe-filling medication dispenser
US5247972A (en) 1991-12-17 1993-09-28 Whittier Medical, Inc. Alignment guide for hypodermic syringe
CA2588574A1 (en) 1991-12-18 1993-06-24 Icu Medical, Inc. Medical valve
US5279597A (en) 1992-01-13 1994-01-18 Arrow International Investment Corp. Catheter compression clamp
CA2093560C (en) 1992-04-10 2005-06-07 Minoru Honda Fluid container
US5328474A (en) 1992-04-13 1994-07-12 B. Braun Medical Inc. Tamper resistant syringe cap
JP2605345Y2 (ja) 1992-05-01 2000-07-10 株式会社大塚製薬工場 薬剤容器
JPH05317383A (ja) 1992-05-19 1993-12-03 Nissho Corp 薬剤容器との連通手段を備えた溶解液容器
US5279576A (en) 1992-05-26 1994-01-18 George Loo Medication vial adapter
US5232109A (en) 1992-06-02 1993-08-03 Sterling Winthrop Inc. Double-seal stopper for parenteral bottle
USD349648S (en) 1992-06-02 1994-08-16 Sterling Winthrop Inc. Closure for vials
GB9211912D0 (en) 1992-06-04 1992-07-15 Drg Flexpak Ltd Vial connector system
JPH0686738U (ja) 1992-06-16 1994-12-20 森下ルセル株式会社 医療用容器
US5419874A (en) * 1992-07-06 1995-05-30 Beckman Instruments, Inc. Synthesis reaction column
USD357733S (en) 1992-07-28 1995-04-25 Pall Corporation Spike detector
US5300034A (en) 1992-07-29 1994-04-05 Minnesota Mining And Manufacturing Company Iv injection site for the reception of a blunt cannula
AU4999793A (en) 1992-08-07 1994-03-03 West Company, Incorporated, The Needleless access stopper
US5308483A (en) 1992-08-27 1994-05-03 Gelman Sciences Inc. Microporous filtration funnel assembly
US5344417A (en) 1992-09-11 1994-09-06 Becton, Dickinson And Company Universal fitting for inoculation receptacles
US5334163A (en) 1992-09-16 1994-08-02 Sinnett Kevin B Apparatus for preparing and administering a dose of a fluid mixture for injection into body tissue
US5603706A (en) 1992-09-29 1997-02-18 Wyatt; Philip Infusion apparatus
US5334179A (en) 1992-10-16 1994-08-02 Abbott Laboratories Latching piercing pin for use with fluid vials of varying sizes
US5562696A (en) 1992-11-12 1996-10-08 Cordis Innovasive Systems, Inc. Visualization trocar
US5547471A (en) 1992-11-19 1996-08-20 Baxter International Inc. In-line drug delivery device for use with a standard IV administration set and a method for delivery
US5385547A (en) 1992-11-19 1995-01-31 Baxter International Inc. Adaptor for drug delivery
ES2115201T3 (es) 1992-12-15 1998-06-16 Sanofi Sa Dispositivo para la preparacion de una solucion, de una suspension o de una emulsion de una sustancia medicinal.
JP2604240Y2 (ja) 1992-12-25 2000-04-24 川澄化学工業株式会社 医療用具
US5405333A (en) 1992-12-28 1995-04-11 Richmond; Frank M. Liquid medicament bag with needleless connector fitting using boat assembly
JPH06239352A (ja) 1993-02-05 1994-08-30 Nissho Corp 溶解液注入セット
US5766211A (en) 1993-02-08 1998-06-16 Wood; Jan Medical device for allowing insertion and drainage into a body cavity
US5269768A (en) 1993-02-08 1993-12-14 Smiths Industries Medical Systems, Inc. Valved suction catheter
US5464111A (en) 1993-03-03 1995-11-07 Sterling Winthrop Closure for medication container
US5312377A (en) 1993-03-29 1994-05-17 Dalton Michael J Tapered luer connector
US5591143A (en) 1993-04-02 1997-01-07 Medrad Inc. Luer connector with torque indicator
US5364386A (en) 1993-05-05 1994-11-15 Hikari Seiyaku Kabushiki Kaisha Infusion unit
US5607439A (en) 1993-06-24 1997-03-04 Yoon; Inbae Safety penetrating instrument with penetrating member moving during penetration and triggered safety member protrusion
CA2124970A1 (en) 1993-06-29 1994-12-30 R. Hayes Helgren Pointed adapter for blunt entry device
US5429614A (en) 1993-06-30 1995-07-04 Baxter International Inc. Drug delivery system
US5445630A (en) 1993-07-28 1995-08-29 Richmond; Frank M. Spike with luer fitting
US5364387A (en) 1993-08-02 1994-11-15 Becton, Dickinson And Company Drug access assembly for vials and ampules
US5397303A (en) 1993-08-06 1995-03-14 River Medical, Inc. Liquid delivery device having a vial attachment or adapter incorporated therein
US5451374A (en) 1993-08-23 1995-09-19 Incutech, Inc. Medicine vessel stopper
US6146362A (en) 1993-08-27 2000-11-14 Baton Development, Inc. Needleless IV medical delivery system
JP3325896B2 (ja) 1993-09-07 2002-09-17 デビオテック ソシエテ アノニム ２成分を混合する注射器装置
SE9303178D0 (sv) 1993-09-29 1993-09-29 Kabi Pharmacia Ab Improvements in injection cartridges
US5806831A (en) 1993-10-13 1998-09-15 Paradis; Joseph R. Control of fluid flow with internal cannula
US5509433A (en) 1993-10-13 1996-04-23 Paradis; Joseph R. Control of fluid flow
US5699821A (en) 1993-10-13 1997-12-23 Paradis; Joseph R. Control of fluid flow
US5472022A (en) 1993-11-02 1995-12-05 Genentech, Inc. Injection pen solution transfer apparatus and method
US5549577A (en) 1993-12-29 1996-08-27 Ivac Corporation Needleless connector
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5554128A (en) 1994-03-09 1996-09-10 Joseph K. Andonian Syringe and vial connector
US5520659A (en) 1994-03-09 1996-05-28 Joseph K. Andonian Syringe needle cover and vial connector
US5454805A (en) 1994-03-14 1995-10-03 Brony; Seth K. Medicine vial link for needleless syringes
US5462317A (en) 1994-03-23 1995-10-31 Keller; Wilhelm A. Adapter for a mixing or dispensing device
US5527306A (en) 1994-04-18 1996-06-18 Haining; Michael L. Vial adapter
USD362718S (en) 1994-04-22 1995-09-26 Mcgaw, Inc. Turn lock cannula
DE4414697C2 (de) 1994-04-27 1998-06-18 Caremed Vertriebsgesellschaft Vorrichtung zum Transferieren und Entnehmen von Flüssigkeiten aus Flaschen, Beuteln oder ähnlichen Behältnissen für medizinische Zwecke
US5746733A (en) 1994-05-19 1998-05-05 Becton, Dickinson And Company Syringe filling and delivery device
US5832971A (en) 1994-05-19 1998-11-10 Becton, Dickinson And Company Syringe filling and delivery device
IL113832A (en) 1994-05-23 1999-11-30 Liposome Co Inc Formulation preparation device
US5649637A (en) 1994-06-02 1997-07-22 Automatic Liquid Packaging, Inc. Torque-resistant closure for a hermetically sealed container
JP3456019B2 (ja) 1994-06-17 2003-10-14 ニプロ株式会社 液体導入針およびそれを用いた乾燥製剤溶解補助具
US5470319A (en) 1994-06-20 1995-11-28 Critical Device Corporation Needleless injection site
US6183448B1 (en) 1994-06-20 2001-02-06 Bruno Franz P. Mayer Needleless injection site
AU2945495A (en) 1994-06-24 1996-01-19 Icu Medical, Inc. Fluid transfer device and method of use
EP0692235A1 (en) 1994-07-14 1996-01-17 International Medication Systems (U.K.) Ltd. Mixing & dispensing apparatus
US5526853A (en) 1994-08-17 1996-06-18 Mcgaw, Inc. Pressure-activated medication transfer system
FR2726768A1 (fr) 1994-11-14 1996-05-15 Debiotech Sa Dispositif de seringue fixable sur un flacon
US6681810B2 (en) 1994-12-20 2004-01-27 Aradigm Corporation Filling device for a needleless injector cartridge
GB9425642D0 (en) 1994-12-20 1995-02-22 Weston Medical Ltd Filling device
US5531695A (en) 1994-12-22 1996-07-02 Sherwood Medical Company Tamper evident sleeve
US5616136A (en) 1995-01-09 1997-04-01 Med-Safe Systems, Inc. Quick release needle removal apparatus
USD369406S (en) 1995-01-13 1996-04-30 Sanofi Winthrop, Inc. Cannula
US5653686A (en) 1995-01-13 1997-08-05 Coulter Corporation Closed vial transfer method and system
US5492147A (en) 1995-01-17 1996-02-20 Aeroquip Corporation Dry break coupling
US5647845A (en) 1995-02-01 1997-07-15 Habley Medical Technology Corporation Generic intravenous infusion system
US5674195A (en) 1995-02-06 1997-10-07 Truthan; Charles Edwin Syringe apparatus and method of mixing liquid medicants within a syringe
DE19504413A1 (de) 1995-02-10 1996-08-22 Pharmacia Gmbh Überleitungsgerät
DE19506163C2 (de) 1995-02-22 1998-01-29 Hans Mueller Vorrichtung zur Behandlung von Blut
US5584819A (en) 1995-03-13 1996-12-17 Kopfer; Rudolph J. Nested blunt/sharp injection assembly
IL114960A0 (en) 1995-03-20 1995-12-08 Medimop Medical Projects Ltd Flow control device
US5651776A (en) 1995-03-22 1997-07-29 Angiodynamics, Inc. Luer-type connector
ATE181909T1 (de) 1995-04-04 1999-07-15 Kuraray Co Verfahren zur herstellung von 6-methylheptan-2-on
US5566729A (en) 1995-04-06 1996-10-22 Abbott Laboratories Drug reconstitution and administration system
DE19513666C1 (de) 1995-04-11 1996-11-28 Behringwerke Ag Vorrichtung zum Zusammenführen einer ersten flüssigen und einer zweiten festen oder flüssigen Komponente mittels Unterdruck unter sterilen Bedingungen
US5902280A (en) 1995-04-13 1999-05-11 Advanced Cytometrix, Inc. Aspiration needle apparatus incorporating its own vacuum and method and adapter for use therewith
US5968022A (en) 1995-04-28 1999-10-19 Saito; Yoshikuni Medical hollow needle and method of production
SE509950C2 (sv) 1995-05-02 1999-03-29 Carmel Pharma Ab Anordning för administrering av toxisk vätska
NZ286445A (en) 1995-05-16 1997-12-19 Ivac Corp Needleless luer connector: deformable piston occludes bore
US5839715A (en) 1995-05-16 1998-11-24 Alaris Medical Systems, Inc. Medical adapter having needleless valve and sharpened cannula
US5685845A (en) 1995-07-11 1997-11-11 Becton, Dickinson And Company Sterile resealable vial connector assembly
US5616203A (en) 1995-07-14 1997-04-01 Merit Medical Method of manufacturing a split ring airless rotatable connector
USD388172S (en) 1995-07-27 1997-12-23 E-Z Kare Good Health Systems, Inc. Nasal dilator
JPH0956782A (ja) 1995-08-24 1997-03-04 Kanae:Kk 受動的薬剤放出用具
FR2738550B1 (fr) 1995-09-11 1997-11-07 Biodome Dispositif d'obturation d'un recipient lui-meme ferme, ensemble pour dispenser un produit comprenant un tel recipient et un tel dispositif d'obturation
CA2185494A1 (en) 1995-09-27 1997-03-28 Jean-Pierre Grimard Resealable vial with connector assembly having a membrane and pusher
US5702019A (en) 1995-09-27 1997-12-30 Becton Dickinson France S.A. Vial having resealable membrane assembly activated by a medical delivery device
DK0957883T3 (da) 1995-10-20 2003-06-30 Schering Ag Adapter til udtagning af en væske fra en med en prop lukket beholder
US5611576A (en) 1995-11-24 1997-03-18 Industrie Borla Spa Female coupling element for haemodialysis medical equipment
US5833213A (en) 1995-12-29 1998-11-10 Rymed Technologies, Inc. Multiple dose drug vial adapter for use with a vial having a pierceable septum and a needleless syringe
ES2176661T3 (es) 1996-01-11 2002-12-01 Duoject Inc Sistema de suministro para productos farmaceuticos envasados en vialesfarmaceuticos.
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
US5879337A (en) 1997-02-27 1999-03-09 Injectimed, Inc. Needle tip guard for hypodermic needles
US6629959B2 (en) 1996-02-27 2003-10-07 Injectimed, Inc. Needle tip guard for percutaneous entry needles
US5810792A (en) 1996-04-03 1998-09-22 Icu Medical, Inc. Locking blunt cannula
USD393722S (en) 1996-04-04 1998-04-21 Icu Medical, Inc. Locking blunt cannula
CA2252404A1 (en) 1996-04-22 1997-10-30 Abbott Laboratories Container closure system
GB9609563D0 (en) 1996-05-08 1996-07-10 Sterimatic Holdings Ltd Venting devices
DE19619026A1 (de) 1996-05-10 1997-11-13 Trinova Gmbh Schnellkupplung
US5752942A (en) 1996-06-20 1998-05-19 Becton Dickinson And Company Five beveled point geometry for a hypodermic needle
US5897526A (en) 1996-06-26 1999-04-27 Vaillancourt; Vincent L. Closed system medication administering system
US6296621B1 (en) 1996-08-23 2001-10-02 Baxter International Inc. Receptacle for passive drug delivery
US5871110A (en) 1996-09-13 1999-02-16 Grimard; Jean-Pierre Transfer assembly for a medicament container having a splashless valve
CA2211629A1 (en) 1996-09-17 1998-03-17 Bernard Sams Vial connector assembly for a medicament container
US5873872A (en) 1996-09-17 1999-02-23 Becton Dickinson And Company Multipositional resealable vial connector assembly for efficient transfer of liquid
FR2753624B1 (fr) 1996-09-25 1999-04-16 Biodome Dispositif de connexion, en particulier entre un recipient avec bouchon perforable et une seringue
US5738144A (en) 1996-10-11 1998-04-14 Aeroquip Corporation Luer connecting coupling
US5895383A (en) 1996-11-08 1999-04-20 Bracco Diagnostics Inc. Medicament container closure with recessed integral spike access means
US5817082A (en) 1996-11-08 1998-10-06 Bracco Diagnostics Inc. Medicament container closure with integral spike access means
US5941848A (en) 1996-11-14 1999-08-24 Baxter International Inc. Passive drug delivery apparatus
WO1998022178A1 (en) 1996-11-18 1998-05-28 Nypro, Inc. Swabbable luer-coned valve
US6883778B1 (en) 1996-11-18 2005-04-26 Nypro Inc. Apparatus for reducing fluid drawback through a medical valve
US6004278A (en) 1996-12-05 1999-12-21 Mdc Investment Holdings, Inc. Fluid collection device with retractable needle
FR2756811B1 (fr) 1996-12-06 1999-02-05 Valois Dispositif de distribution de produit fluide du type bicomposant
GB9700177D0 (en) 1997-01-07 1997-02-26 Nycomed Imaging As Container
GB9701413D0 (en) 1997-01-24 1997-03-12 Smithkline Beecham Biolog Novel device
US5954104A (en) 1997-02-28 1999-09-21 Abbott Laboratories Container cap assembly having an enclosed penetrator
US5924584A (en) 1997-02-28 1999-07-20 Abbott Laboratories Container closure with a frangible seal and a connector for a fluid transfer device
USD405522S (en) 1997-04-18 1999-02-09 Vital Signs Inc. Breathing tube for conveying oxygen or anesthesia gas to lungs and conveying exhaled gas away from lungs of patient
US5911710A (en) 1997-05-02 1999-06-15 Schneider/Namic Medical insertion device with hemostatic valve
US5772652A (en) 1997-05-14 1998-06-30 Comar, Inc. Stab cap for a vial having a puncturable seal
JPH1147274A (ja) 1997-06-03 1999-02-23 Takeda Chem Ind Ltd ２室型注射器及び２室型注射器用接続具
IT1293856B1 (it) 1997-06-27 1999-03-10 Borla Ind Dispositivo trasduttore-protettore per linee biomedicali di emodialisi
US5755696A (en) 1997-06-30 1998-05-26 Becton, Dickinson And Company Syringe filling and delivery device
US5899468A (en) 1997-07-02 1999-05-04 Rehrig Pacific Company Organic waste cart with vented lid
US5820621A (en) 1997-07-29 1998-10-13 Becton, Dickinson And Company Medical fluid transfer and delivery device
JPH11104215A (ja) 1997-08-12 1999-04-20 Becton Dickinson Fr Sa ガラス瓶コネクタアセンブリ
US7125397B2 (en) 1997-08-20 2006-10-24 B. Braun Melsungen Ag Protective device for an injection needle
IL121605A (en) 1997-08-22 2001-03-19 Medimop Medical Projects Ltd Fluid access assembly and a method for preparing a liquid drug
US5834744A (en) 1997-09-08 1998-11-10 The Rubbright Group Tubular microwave applicator
US5919182A (en) 1997-09-12 1999-07-06 Becton, Dickinson And Company Medical fluid transfer and delivery device
US6089541A (en) 1998-09-10 2000-07-18 Halkey-Roberts Corporation Valve having a valve body and a deformable stem therein
US6036171A (en) 1997-09-17 2000-03-14 Halkey-Roberts Corporation Swabbable valve assembly
US5925029A (en) 1997-09-25 1999-07-20 Becton, Dickinson And Company Method and apparatus for fixing a connector assembly onto a vial with a crimp cap
US6090093A (en) 1997-09-25 2000-07-18 Becton Dickinson And Company Connector assembly for a vial having a flexible collar
US5944700A (en) 1997-09-26 1999-08-31 Becton, Dickinson And Company Adjustable injection length pen needle
US5935112A (en) 1997-10-15 1999-08-10 Stevens; Brian W. Hemostasis valve with catheter/guidewire seals
US5902298A (en) 1997-11-07 1999-05-11 Bracco Research Usa Medicament container stopper with integral spike access means
USD399559S (en) 1997-11-12 1998-10-13 Incutech, Inc. Pediatric catheter connector
IT236233Y1 (it) 1997-11-26 2000-08-08 Eurospital S P A Dispositivo per il collegamento di un contenitore di prodottofarmaceutico ad una sacca di prodotto liquido per effettuare il
US6159192A (en) 1997-12-04 2000-12-12 Fowles; Thomas A. Sliding reconstitution device with seal
US6457488B2 (en) 1998-01-08 2002-10-01 George Loo Stopcock having axial port for syringe twist actuation
FR2773735B1 (fr) 1998-01-20 2000-02-25 Becton Dickinson France Dispositif de confinement etanche
US6179822B1 (en) 1998-01-20 2001-01-30 Bracco Research Usa Single use universal access device/medical container assembly
US6179823B1 (en) 1998-01-20 2001-01-30 Bracco Research Usa Multiple use universal connector flexible medical container assembly
US6096011A (en) 1998-01-29 2000-08-01 Medrad, Inc. Aseptic connector and fluid delivery system using such an aseptic connector
US6681946B1 (en) 1998-02-26 2004-01-27 Becton, Dickinson And Company Resealable medical transfer set
US6003566A (en) 1998-02-26 1999-12-21 Becton Dickinson And Company Vial transferset and method
US6382442B1 (en) 1998-04-20 2002-05-07 Becton Dickinson And Company Plastic closure for vials and other medical containers
US6080132A (en) 1998-02-27 2000-06-27 Abbott Laboratories Apparatus for altering characteristics of a fluid
US6221065B1 (en) 1998-04-03 2001-04-24 Filtertek Inc. Self-priming needle-free “Y”-adapter
US6378714B1 (en) 1998-04-20 2002-04-30 Becton Dickinson And Company Transferset for vials and other medical containers
US6209738B1 (en) 1998-04-20 2001-04-03 Becton, Dickinson And Company Transfer set for vials and medical containers
US6957745B2 (en) 1998-04-20 2005-10-25 Becton, Dickinson And Company Transfer set
US6692478B1 (en) 1998-05-04 2004-02-17 Paradis Joseph R Swabbable needleless vial access
USD422357S (en) 1998-05-04 2000-04-04 Bracco Research Usa Stopper for medication container
US5921419A (en) 1998-05-04 1999-07-13 Bracco Research Usa Universal stopper
US6117114A (en) 1998-05-07 2000-09-12 Paradis; Joseph R. Swabbable needleless valve adaptations
USD410740S (en) 1998-05-11 1999-06-08 Incutech, Inc. Pediatric catheter connector
CA2262477C (en) 1998-05-16 2008-02-12 Bracco International B.V. Multiple use universal stopper
MXPA00011767A (es) 1998-05-29 2002-10-17 Lawrence A Lynn Receptor luer y metodos para transferir fluidos.
US6245044B1 (en) 1998-07-17 2001-06-12 Becton, Dickinson And Company Variable extension combined spinal/epidural needle set and method for its use
US6358236B1 (en) 1998-08-06 2002-03-19 Baxter International Inc. Device for reconstituting medicaments for injection
US6276568B1 (en) 1998-08-21 2001-08-21 Pharmacia & Upjohn Company Spray bottle grip
GB2359754B (en) 2000-03-03 2004-04-28 Nmt Group Plc Needle sheath
US6113583A (en) 1998-09-15 2000-09-05 Baxter International Inc. Vial connecting device for a sliding reconstitution device for a diluent container
US7425209B2 (en) 1998-09-15 2008-09-16 Baxter International Inc. Sliding reconstitution device for a diluent container
US7074216B2 (en) 1998-09-15 2006-07-11 Baxter International Inc. Sliding reconstitution device for a diluent container
AR021220A1 (es) 1998-09-15 2002-07-03 Baxter Int DISPOSITIVO DE CONEXIoN PARA ESTABLECER UNA COMUNICACIoN FLUíDA ENTRE UN PRIMER RECIPIENTE Y UN SEGUNDO RECIPIENTE.
FR2783808B1 (fr) 1998-09-24 2000-12-08 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US6726672B1 (en) 1998-09-28 2004-04-27 Icu Medical, Inc. Intravenous drug access system
US6113068A (en) 1998-10-05 2000-09-05 Rymed Technologies Swabbable needleless injection port system having low reflux
USD430291S (en) 1998-10-08 2000-08-29 Becton, Dickinson And Company Medical container
USD431864S (en) 1998-11-24 2000-10-10 Becton Dickinson And Company Tamper evident cap for a tip cap
USD427308S (en) 1999-01-22 2000-06-27 Medimop Medical Projects Ltd. Vial adapter
US6364866B1 (en) 1999-01-22 2002-04-02 Douglas Furr Syringe loading aid
FR2789369B1 (fr) 1999-02-10 2001-04-27 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
EP1034809A1 (en) 1999-02-26 2000-09-13 F. Hoffmann-La Roche Ag Administering device for medication
USD445895S1 (en) 1999-03-05 2001-07-31 Maersk Medical A/S Funnel for a catheter
JP2000262497A (ja) 1999-03-16 2000-09-26 Sekisui Chem Co Ltd 分注器具、分注システム及び分注方法
FR2790948B1 (fr) 1999-03-18 2001-06-22 Sedat Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une capsule
US6099511A (en) 1999-03-19 2000-08-08 Merit Medical Systems, Inc. Manifold with check valve positioned within manifold body
USD427309S (en) 1999-04-30 2000-06-27 Incutech, Inc. Pediatric catheter connector
US6231552B1 (en) 1999-05-04 2001-05-15 Saf-T-Med, Inc. Threaded latching mechanism
US6092692A (en) 1999-05-10 2000-07-25 Riskin; Jane G. Medication applicator with incident reminder system
US6156025A (en) 1999-06-17 2000-12-05 Bracco Research Usa Inc. Twist valve
JP4329954B2 (ja) 1999-06-29 2009-09-09 東洋ゴム工業株式会社 空気入りタイヤ
US6706022B1 (en) 1999-07-27 2004-03-16 Alaris Medical Systems, Inc. Needleless medical connector with expandable valve mechanism
USD428141S (en) 1999-08-04 2000-07-11 Pharmacia & Upjohn Company Spray bottle grip
US6348044B1 (en) 1999-10-12 2002-02-19 George D. N. Coletti Method and apparatus for recapping single-use hypodermic needles
CN1236826C (zh) 1999-10-22 2006-01-18 安塔雷斯制药公司 医用注射器以及用于该注射器中的药物装载系统
US7198618B2 (en) 1999-11-04 2007-04-03 Tyco Healthcare Group Lp Safety shield for medical needles
US6453956B2 (en) 1999-11-05 2002-09-24 Medtronic Minimed, Inc. Needle safe transfer guard
US6253804B1 (en) 1999-11-05 2001-07-03 Minimed Inc. Needle safe transfer guard
FR2800713B1 (fr) 1999-11-05 2002-01-04 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
DE19960226C1 (de) 1999-12-14 2001-05-10 Fresenius Ag Sterilitäterhaltendes Konnektionssystem für medizinische Systeme und dessen Verwendung
US6503240B1 (en) 2000-01-24 2003-01-07 Brocco Diagnostics, Inc. Vial access adapter
US6139534A (en) 2000-01-24 2000-10-31 Bracco Diagnostics, Inc. Vial access adapter
US6832994B2 (en) 2000-01-24 2004-12-21 Bracco Diagnostics Inc. Table top drug dispensing vial access adapter
US7799009B2 (en) 2000-01-24 2010-09-21 Bracco Diagnostics Inc. Tabletop drug dispensing vial access adapter
US6544246B1 (en) 2000-01-24 2003-04-08 Bracco Diagnostics, Inc. Vial access adapter and vial combination
USD445501S1 (en) 2000-01-24 2001-07-24 Bracco Diagnostics, Inc. Vial access adapter
WO2001060436A1 (en) 2000-02-15 2001-08-23 Comar, Inc. Needleless access apparatus and system
ES2223644T3 (es) 2000-02-16 2005-03-01 Haselmeier S.A R.L. Procedimiento de reconstitucion de un liquido de inyeccion, y aparato para llevar a cabo un procedimiento de este tipo.
US6530903B2 (en) 2000-02-24 2003-03-11 Xiping Wang Safety syringe
US6173868B1 (en) 2000-03-08 2001-01-16 Calmar Inc. Nasal sprayer with folding actuator
US6652509B1 (en) 2000-04-03 2003-11-25 Abbott Laboratories Housing capable of connecting a container to a medical device
JP4372310B2 (ja) 2000-04-10 2009-11-25 ニプロ株式会社 混注用アダプター
US6884253B1 (en) 2000-05-16 2005-04-26 Taut, Inc. Penetrating tip for trocar assembly
US6343629B1 (en) 2000-06-02 2002-02-05 Carmel Pharma Ab Coupling device for coupling a vial connector to a drug vial
US6499617B1 (en) 2000-07-17 2002-12-31 Brocco Diagnostics, Inc. Rotary seal stopper
JP2002035140A (ja) 2000-07-21 2002-02-05 Terumo Corp コネクタ
JP5058425B2 (ja) 2000-08-02 2012-10-24 ベクトン・ディキンソン・アンド・カンパニー ペン針および安全シールドシステム
US20030036725A1 (en) 2000-09-21 2003-02-20 Gilad Lavi Reconstitution and injection system
FR2815328B1 (fr) 2000-10-17 2002-12-20 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US6769430B1 (en) 2000-10-31 2004-08-03 Kimberly-Clark Worldwide, Inc. Heat and moisture exchanger adaptor for closed suction catheter assembly and system containing the same
JP2002177392A (ja) 2000-11-08 2002-06-25 West Pharmaceutical Services Inc 注射器安全装置
US6666852B2 (en) 2000-12-04 2003-12-23 Bracco Diagnostics, Inc. Axially activated vial access adapter
FR2817566B1 (fr) 2000-12-04 2003-02-07 Freyssinet Int Stup Toron individuellement protege, son utilisation dans la construction, et procede de fabrication
US20020087118A1 (en) 2000-12-29 2002-07-04 Duoject Medical Systems Inc. Pharmaceutical delivery system
US6558365B2 (en) 2001-01-03 2003-05-06 Medimop Medical Projects, Ltd. Fluid transfer device
USD468015S1 (en) 2001-01-22 2002-12-31 Astra Tech Ab Combined connector with valve and non-return valve for medical equipment
US6474375B2 (en) 2001-02-02 2002-11-05 Baxter International Inc. Reconstitution device and method of use
WO2002066100A2 (en) 2001-02-20 2002-08-29 Medrad, Inc. Syringes, connectors, and syringe and connector systems for use in fluid delivery systems
US6503244B2 (en) 2001-03-07 2003-01-07 Micro Therapeutics, Inc. High pressure injection system
US6656433B2 (en) 2001-03-07 2003-12-02 Churchill Medical Systems, Inc. Vial access device for use with various size drug vials
US6685692B2 (en) 2001-03-08 2004-02-03 Abbott Laboratories Drug delivery system
US20020138045A1 (en) 2001-03-20 2002-09-26 Moen Michael E. Quick connect fitting
PT1383456E (pt) 2001-03-27 2007-05-31 Lilly Co Eli Kit de montagem incluindo uma agulha de seringa com saída lateral, para preparação de um remédio num cartucho destinado a um dispositivo de injecção
US6581593B1 (en) 2001-04-03 2003-06-24 Darren A. Rubin Universal oxygen connector system
US20030028156A1 (en) 2001-05-07 2003-02-06 Nexell Therapeutics, Inc. Fluid connector devices and methods of use
JP2002355318A (ja) 2001-06-01 2002-12-10 Terumo Corp 弁体付コネクター
EP1264609B1 (en) 2001-06-06 2006-01-18 Graziano Azzolini High-sterility and high-capacity connector for lines for outflow from bottles
USD457954S1 (en) 2001-06-19 2002-05-28 Becton, Dickinson And Company Syringe tip cap
JP2003033441A (ja) 2001-07-23 2003-02-04 Terumo Corp 三方活栓
US6453949B1 (en) 2001-08-08 2002-09-24 Sam Chau Plug for medical bayonet connectors and drug infusion ports
US6745998B2 (en) 2001-08-10 2004-06-08 Alaris Medical Systems, Inc. Valved male luer
USD476731S1 (en) 2001-08-27 2003-07-01 Kimberly-Clark Worldwide, Inc. Bendable connector
DE10142450C1 (de) 2001-08-31 2003-06-18 Aventis Behring Gmbh Vorrichtung zum Zusammenführen von Komponenten unter sterilen Bedingungen
FR2829691B1 (fr) 2001-09-17 2004-07-09 Sedat Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une carpule
US7354422B2 (en) 2001-09-26 2008-04-08 B. Braun Melsungen Ag Spring launched needle safety clip
JP4817564B2 (ja) 2001-09-28 2011-11-16 株式会社細川洋行 ニードルケース及び輸液容器
US20030069550A1 (en) 2001-10-06 2003-04-10 Sharp M. Keith Hypodermic needle
US6715520B2 (en) 2001-10-11 2004-04-06 Carmel Pharma Ab Method and assembly for fluid transfer
US20030073971A1 (en) 2001-10-17 2003-04-17 Saker Gordon Mark Universal connector and method for securing flexible tube assemblies
JP3945480B2 (ja) 2001-11-14 2007-07-18 株式会社ジェイ・エム・エス 三方活栓及び当該三方活栓を用いた輸液回路又は輸血回路
US6802828B2 (en) 2001-11-23 2004-10-12 Duoject Medical Systems, Inc. System for filling and assembling pharmaceutical delivery devices
US6802490B2 (en) 2001-11-29 2004-10-12 Alaris Medical Systems, Inc. Needle free medical connector with expanded valve mechanism and method of fluid flow control
KR100879498B1 (ko) 2001-11-30 2009-01-20 노보 노르디스크 에이/에스 안전 바늘 조립체
EP1453561B1 (en) 2001-12-13 2016-08-31 Becton Dickinson and Company Needle closure system removal device
ES2262733T3 (es) 2001-12-17 2006-12-01 Bristol-Myers Squibb Company Dispositivo de transferencia y sistema que comprende un conjunto de tapa, un recipiente y el dispositivo de transferencia.
US6651956B2 (en) 2002-01-31 2003-11-25 Halkey-Roberts Corporation Slit-type swabable valve
US6875205B2 (en) 2002-02-08 2005-04-05 Alaris Medical Systems, Inc. Vial adapter having a needle-free valve for use with vial closures of different sizes
FR2836129B1 (fr) 2002-02-20 2004-04-02 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US8562583B2 (en) 2002-03-26 2013-10-22 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US9440046B2 (en) 2002-04-04 2016-09-13 Angiodynamics, Inc. Venous insufficiency treatment method
US7744581B2 (en) 2002-04-08 2010-06-29 Carmel Pharma Ab Device and method for mixing medical fluids
US7867215B2 (en) 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
US6740277B2 (en) 2002-04-24 2004-05-25 Becton Dickinson And Company Process of making a catheter
USD472630S1 (en) 2002-04-30 2003-04-01 Sterling Medivations, Inc. Pen needle catheter connector
USD472316S1 (en) 2002-04-30 2003-03-25 Sterling Medivations, Inc. Pen needle catheter connector
US6914212B2 (en) 2002-05-01 2005-07-05 Becton Dickinson And Company Method of making a needle and a needle
USD476733S1 (en) 2002-05-09 2003-07-01 Becton, Dickinson And Company Medical needle assembly
MXPA04011395A (es) 2002-05-16 2005-02-17 Scott Lab Inc Mecanismos de introduccion a recipiente de farmaco y metodo.
US20030236543A1 (en) 2002-06-25 2003-12-25 Brenneman Allen J. Polygonal cross section lancet needle
JP4427965B2 (ja) 2002-07-02 2010-03-10 ニプロ株式会社 連通手段付き薬液容器
SE523001C2 (sv) 2002-07-09 2004-03-23 Carmel Pharma Ab En kopplingsdel, en koppling, en infusionspåse, en infusionsanordning och ett förfarande för överföring av medicinska substanser
JP4209642B2 (ja) 2002-07-26 2009-01-14 川澄化学工業株式会社 針カバー及びキャップ付針カバー並びに針カバー付翼付針
US7326188B1 (en) 2002-08-02 2008-02-05 Elcam Medical Anesthesia manifold and induction valve
US7083600B2 (en) 2002-08-08 2006-08-01 Advanced Medical Sharps, Inc. Safety needle and shield
JP2004097253A (ja) 2002-09-04 2004-04-02 Nipro Corp 液体移注具
USD482121S1 (en) 2002-09-17 2003-11-11 Becton Dickinson And Company Needleless luer access port
USD482447S1 (en) 2002-09-17 2003-11-18 Becton Dickinson And Company Needleless luer access port
US6979318B1 (en) 2002-10-07 2005-12-27 Lemaitre Vascular, Inc. Catheter introducer
US20040073189A1 (en) 2002-10-09 2004-04-15 Phil Wyatt Vial access transfer set
US7544191B2 (en) 2002-10-22 2009-06-09 Baxter International Inc. Formed, filled, sealed solution container, port and method for establishing flow between the container and an administration set
USD483869S1 (en) 2002-10-29 2003-12-16 Pre Holding, Inc. Tubing connector
AU2003281876A1 (en) 2002-11-08 2004-06-07 Duoject Medical Systems Inc. Pharmaceutical delivery systems and methods for using same
US8100879B2 (en) 2002-11-18 2012-01-24 Nestec S.A. Connector device for enteral administration set
CH696186A5 (de) 2002-11-25 2007-02-15 Tecpharma Licensing Ag Vorrichtung zur Sicherung von Injektionsnadeln.
USD506256S1 (en) 2002-11-26 2005-06-14 Nipro Corporation Adapter for transfer of medical solution
US7086431B2 (en) 2002-12-09 2006-08-08 D'antonio Consultants International, Inc. Injection cartridge filling apparatus
USD483487S1 (en) 2002-12-19 2003-12-09 Becton Dickinson And Company Stopcock device
JP4341239B2 (ja) 2002-12-19 2009-10-07 ニプロ株式会社 液体移注具
US7125396B2 (en) 2002-12-30 2006-10-24 Cardinal Health 303, Inc. Safety catheter system and method
US7140592B2 (en) 2002-12-31 2006-11-28 Cardinal Health 303, Inc. Self-sealing male Luer connector with biased valve plug
US20040143226A1 (en) 2003-01-16 2004-07-22 Becton, Dickinson And Company Blood collection set with venting mechanism
US20040143218A1 (en) 2003-01-21 2004-07-22 Animas Corporation Needle having optimum grind for reduced insertion force
CA2514673A1 (en) 2005-08-05 2007-02-05 Duoject Medical Systems Inc. Fluid transfer assembly for pharmaceutical delivery system and method for using same
US20040162540A1 (en) 2003-02-13 2004-08-19 Becton, Dickinson And Company Transfer device
EP1454609B1 (de) 2003-03-05 2012-10-24 CSL Behring GmbH Transfervorrichtung
ES2293105T3 (es) 2003-03-06 2008-03-16 Csl Behring Gmbh Dispositivo de transferencia, en particular para fluidos medicinales.
US20040181192A1 (en) 2003-03-11 2004-09-16 Cuppy Michael John Vascular access device and method of using same
US7470262B2 (en) 2003-03-17 2008-12-30 Nipro Corporation Medical valve
US7470265B2 (en) 2003-03-20 2008-12-30 Nxstage Medical, Inc. Dual access spike for infusate bags
US7024968B2 (en) 2003-03-26 2006-04-11 Boston Scientific Scimed, Inc. Luer lock wrench
US7001369B2 (en) 2003-03-27 2006-02-21 Scimed Life Systems, Inc. Medical device
US7040598B2 (en) 2003-05-14 2006-05-09 Cardinal Health 303, Inc. Self-sealing male connector
USD495416S1 (en) 2003-05-30 2004-08-31 Alaris Medical Systems, Inc. Vial access device
US20040249235A1 (en) 2003-06-03 2004-12-09 Connell Edward G. Hazardous material handling system and method
US6948522B2 (en) 2003-06-06 2005-09-27 Baxter International Inc. Reconstitution device and method of use
EP1639286B1 (en) 2003-06-17 2014-12-03 Filtertek Inc. Fluid handling device
FR2856660A1 (fr) 2003-06-30 2004-12-31 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
ITMO20030204A1 (it) 2003-07-14 2005-01-15 Gambro Lundia Ab Sacca per dialisi, set per dialisi comprendente detta
JP3883527B2 (ja) 2003-07-17 2007-02-21 ニプロ株式会社 トランスファーニードル
US7488297B2 (en) 2003-07-30 2009-02-10 Patrice Flaherty Blood collecting devices
US6960164B2 (en) 2003-08-01 2005-11-01 Neosurg Technologies, Inc. Obturator tip for a trocar
FR2858931B1 (fr) 2003-08-21 2007-04-13 Becton Dickinson France Dispositif d'administration orale d'un medicament
US20050082828A1 (en) 2003-09-12 2005-04-21 Wicks Jeffrey C. Releasable connection assembly for joining tubing sections
CN1886295B (zh) 2003-10-30 2010-05-26 泰瓦医学有限公司 药物混合系统和药物混合方法
FR2863161B1 (fr) 2003-12-05 2006-09-01 Map France Capuchon pour conditionnement de securite pour flacon a usage medical
US7712637B2 (en) 2003-12-11 2010-05-11 Gregory Lambrecht Wine extraction and preservation device and method
US20080009822A1 (en) 2003-12-18 2008-01-10 Halkey-Roberts Corporation Needleless access vial
AU2004317020A1 (en) 2003-12-18 2005-09-15 Halkey-Roberts Corporation Needleless access vial
US20050137523A1 (en) 2003-12-22 2005-06-23 Wyatt Philip W. Medicament administration apparatus
US8454573B2 (en) 2008-05-06 2013-06-04 Philip Wyatt Medicament administration apparatus
US6997916B2 (en) 2004-01-02 2006-02-14 Smiths Medical Asd, Inc. Fluid transfer holder assembly and a method of fluid transfer
US6994315B2 (en) 2004-01-13 2006-02-07 Rymed Technologies, Inc. Swabbable needle-free injection port valve system with neutral fluid displacement
US7530546B2 (en) 2004-01-13 2009-05-12 Rymed Technologies, Inc. Swabbable needle-free injection port valve system with zero fluid displacement
DE102004005435B3 (de) 2004-02-04 2005-09-15 Haindl, Hans, Dr. Medizinisches Transfergerät
IL160891A0 (en) 2004-03-16 2004-08-31 Auto-mix needle
US20050209554A1 (en) 2004-03-19 2005-09-22 Sergio Landau Needle-free single-use cartridge and injection system
JP4968607B2 (ja) 2004-03-26 2012-07-04 クック メディカル テクノロジーズ エルエルシー ルアー取付接続を改善するための方法及び装置
IL161660A0 (en) 2004-04-29 2004-09-27 Medimop Medical Projects Ltd Liquid drug delivery device
DE102004021670A1 (de) 2004-05-03 2005-12-01 Saint-Gobain Calmar Gmbh Manuell betätigbarer Spender mit Schutzkappe
FR2869795B1 (fr) 2004-05-07 2006-08-04 Sedat Sa Dispositif de transfert bidirectionnel
US20050261637A1 (en) 2004-05-21 2005-11-24 Halkey-Roberts Corporation T-port with swabbable valve
DE102004036051A1 (de) 2004-07-24 2006-02-16 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Spritze
US7615041B2 (en) 2004-07-29 2009-11-10 Boston Scientific Scimed, Inc. Vial adaptor
DE202004012714U1 (de) 2004-08-12 2004-11-04 Smiths Medical Deutschland Gmbh Luer-Lock-Verbinder für medizinische Geräte
CA2836337C (en) 2004-09-03 2015-12-01 Elcam Medical Agricultural Cooperative Association Ltd. Stopcock
US20060161192A1 (en) 2004-09-03 2006-07-20 Young Christopher S Wound needle with composite cutting edge
US20060106832A1 (en) 2004-10-04 2006-05-18 Ben-Dyke Andy D Method and system for implementing an enhanced database
US7731678B2 (en) 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
JP4821947B2 (ja) 2004-10-19 2011-11-24 朝日インテック株式会社 薬液注入装置
US7771383B2 (en) 2004-10-22 2010-08-10 Medegen, Inc. Fluid control device with valve and methods of use
US20060089594A1 (en) 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device
US7192423B2 (en) 2004-11-17 2007-03-20 Cindy Wong Dispensing spike assembly with removable indicia bands
US7241285B1 (en) 2004-12-06 2007-07-10 Medical Ventures, Inc. Medical site connection
FR2878737B1 (fr) 2004-12-07 2007-03-16 Maptech Soc Par Actions Simpli Dispositif de securite pour flacon a usage medical
US7645274B2 (en) 2004-12-10 2010-01-12 Cardinal Health 303, Inc. Self-sealing male luer connector with multiple seats
US7523967B2 (en) 2004-12-13 2009-04-28 Alcon, Inc. Tubing fitting
US20060135948A1 (en) 2004-12-16 2006-06-22 Medtronic Vascular, Inc., A Delaware Corporation Multi-exchange catheter guide member with improved seal
US7935070B2 (en) * 2005-01-28 2011-05-03 Fresenius Medical Care North America Systems and methods for dextrose containing peritoneal dialysis (PD) solutions with neutral pH and reduced glucose degradation product
US7651482B2 (en) 2005-02-04 2010-01-26 Boston Scientific Scimed, Inc. Non-coring needles and methods of manufacturing same
ES2354018T3 (es) 2005-02-14 2011-03-09 Medimop Medical Projects Ltd. Dispositivo médico para la reconstitución in situ de fármacos líquidos en recipientes medicinales.
US20070060904A1 (en) 2005-03-14 2007-03-15 Becton, Dickinson And Company Filling system and method for syringes with short needles
US7666172B2 (en) 2005-03-15 2010-02-23 Plaridel Cerna Atil Medical needle having a closed tip
US20060253084A1 (en) 2005-05-03 2006-11-09 Greg Nordgren Outdwelling slit valves and assemblies for medical liquid flow through a cannula and related methods
US7648491B2 (en) 2005-05-13 2010-01-19 Bob Rogers Medical substance transfer system
CA111438S (fr) 2005-05-23 2006-12-22 Rexam Dispensing Sys Pulvérisateur nasal
US20070088294A1 (en) 2005-07-06 2007-04-19 Fangrow Thomas F Jr Medical connector with closeable male luer
JP2007024928A (ja) 2005-07-12 2007-02-01 Nidec Sankyo Corp 光ビーム出射装置および画像形成装置
WO2007015233A1 (en) 2005-08-01 2007-02-08 Medimop Medical Projects Ltd Liquid drug delivery system
US8070739B2 (en) 2005-08-11 2011-12-06 Medimop Medical Projects Ltd. Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials
WO2007053799A2 (en) 2005-10-19 2007-05-10 Cd Solutions, Llc Apparatus and method for mixing and transferring medications
US7611502B2 (en) 2005-10-20 2009-11-03 Covidien Ag Connector for enteral fluid delivery set
JP2009513294A (ja) 2005-10-30 2009-04-02 メディモップ・メディカル・プロジェクツ・リミテッド ニードルレス添加剤制御バルブ
PL1951344T3 (pl) 2005-11-07 2015-02-27 Borla Ind Odpowietrzana bezpieczna podczas obsługi przystawka pośrednicząca do fiolki
DE102005055326A1 (de) 2005-11-11 2007-05-16 Storz Karl Gmbh & Co Kg Anschluss für ein medizinisches Saug- oder Spülinstrument
JP2007143813A (ja) 2005-11-28 2007-06-14 Nippon Sherwood Medical Industries Ltd 医療用活栓
US20070191767A1 (en) 2005-12-16 2007-08-16 Medtronic Vascular, Inc. Bifurcated Catheter Joints
US7981101B2 (en) 2005-12-30 2011-07-19 Carefusion 303, Inc. Medical vial adapter with reduced diameter cannula and enlarged vent lumen
EP1820485B1 (de) 2006-02-16 2009-11-11 F.Hoffmann-La Roche Ag System und Vorrichtung zum Entnehmen von Pharmazeutika
JP2007222472A (ja) 2006-02-24 2007-09-06 Nipro Corp 薬剤微量投与具セット
EP1911432A1 (en) * 2006-10-10 2008-04-16 Novo Nordisk A/S A mixing unit
IL174352A0 (en) 2006-03-16 2006-08-20 Medimop Medical Projects Ltd Medical devices for use with carpules
JP4769103B2 (ja) 2006-03-17 2011-09-07 日本シャーウッド株式会社 コネクタ
FR2898812B1 (fr) 2006-03-24 2008-06-13 Technoflex Sa Connecteur luer, connecteur medical et set de transfert comportant un tel connecteur
JP4775638B2 (ja) 2006-03-31 2011-09-21 株式会社ジェイ・エム・エス 連通部材、およびそれを用いた医療用容器、並びに輸液調剤用具セット
US7547300B2 (en) 2006-04-12 2009-06-16 Icu Medical, Inc. Vial adaptor for regulating pressure
EP2014322A4 (en) 2006-04-18 2012-09-26 Zhongshan Botai Pharmaceutic Instr Co Ltd STERILIZED SYRINGE FOR MIXING MEDICINES
JP4820703B2 (ja) 2006-04-28 2011-11-24 日本シャーウッド株式会社 液体混注具
JP4871019B2 (ja) 2006-05-15 2012-02-08 日本コヴィディエン株式会社 液体混注具
ES2425579T3 (es) 2006-05-25 2013-10-16 Bayer Healthcare, Llc Dispositivo de reconstitución
CN101453949B (zh) 2006-06-02 2011-05-18 旭石墨尼龙株式会社 穿刺针及具有它的柳叶刀
KR101298462B1 (ko) 2006-06-19 2013-08-23 니프로 가부시키가이샤 약액 조제용 키트
JP2008005974A (ja) 2006-06-28 2008-01-17 Nippon Sherwood Medical Industries Ltd ルアー固定フィッティング接続構造
US20090177178A1 (en) 2006-07-21 2009-07-09 Polimoon Medical Packaging A/S Connector device and method for sterile mixing
USD561348S1 (en) 2006-08-17 2008-02-05 Medimop Medical Projects Ltd. Vial adapter
US7670326B2 (en) 2006-09-25 2010-03-02 Teva Medical Ltd.. Syringe adapter element in drug mixing system
USD580558S1 (en) 2006-09-29 2008-11-11 Fujifilm Corporation Cap of cartridge for component extraction
US8167863B2 (en) 2006-10-16 2012-05-01 Carefusion 303, Inc. Vented vial adapter with filter for aerosol retention
US8105314B2 (en) 2006-10-25 2012-01-31 Icu Medical, Inc. Medical connector
WO2008067511A1 (en) 2006-11-30 2008-06-05 Medi-Physics, Inc. Dual-lumen needle with an elongate notch opening
WO2008067506A1 (en) 2006-11-30 2008-06-05 Medi-Physics, Inc. Dual-lumen needle
US7758082B2 (en) 2006-12-05 2010-07-20 Nxstage Medical, Inc. Fluid line connector safety device
US20080135051A1 (en) 2006-12-07 2008-06-12 George Lee Air Line Adapter Structure Of Suction Apparatus
US8002756B2 (en) 2006-12-08 2011-08-23 Becton, Dickinson And Company Method and apparatus for delivering a therapeutic substance through an injection port
US7900659B2 (en) 2006-12-19 2011-03-08 Carefusion 303, Inc. Pressure equalizing device for vial access
AU2007335240B2 (en) 2006-12-21 2011-08-11 Ssb Technology Pty Ltd Needle tip
IL180565A0 (en) 2007-01-04 2007-06-03 Ilan Brand An improved stopcock for administering medicaments into the patient's body
US8523830B2 (en) 2007-01-16 2013-09-03 Catheter Connections Disinfecting caps for medical female luer connectors
GB2446778A (en) 2007-02-01 2008-08-27 Pa Knowledge Ltd Syringe adaptor
US7883499B2 (en) 2007-03-09 2011-02-08 Icu Medical, Inc. Vial adaptors and vials for regulating pressure
GB0705782D0 (en) 2007-03-26 2007-05-02 Novartis Ag Vial assemblies
IL182605A0 (en) 2007-04-17 2007-07-24 Medimop Medical Projects Ltd Fluid control device with manually depressed actuator
BRPI0810542A2 (pt) 2007-04-23 2014-10-21 Plastmed Ltd Método para transferência sem contaminação de líquido, aparelho de transferência de fluídos, método de acoplamento do aparelho, seção conectora para uso em uma operação de transferência de fluídos e método de acoplamento da seção conectora
IL182922A0 (en) 2007-05-02 2007-09-20 Medimop Medical Projects Ltd Automatic liquid drug reconstitution apparatus
US20080306439A1 (en) 2007-06-08 2008-12-11 Nelson M Bud Devices for mixing and applying a fluid composition
USD588693S1 (en) 2007-06-12 2009-03-17 Nordson Corporation Liquid dispensing syringe
US8657803B2 (en) 2007-06-13 2014-02-25 Carmel Pharma Ab Device for providing fluid to a receptacle
US8241265B2 (en) 2007-08-01 2012-08-14 Hospira, Inc. Medicament admixing system
GB0716159D0 (en) 2007-08-17 2007-09-26 Precisense As Injection apparatus
EP2188004A4 (en) 2007-08-21 2015-06-17 Yukon Medical Llc SYSTEM FOR ACCESSING A BOTTLE AND INJECTION
WO2009029010A1 (en) 2007-08-30 2009-03-05 Carmel Pharma Ab Device, sealing member and fluid container
US8287513B2 (en) 2007-09-11 2012-10-16 Carmel Pharma Ab Piercing member protection device
BRPI0822769A2 (pt) 2007-09-18 2015-06-30 Sabiedriba Ar Ierobezotu Atbildibu Sdmd Dispositivo de agulha de segurança
WO2009038860A2 (en) 2007-09-18 2009-03-26 Medeq Llc Medicament mixing and injection apparatus
IL186290A0 (en) 2007-09-25 2008-01-20 Medimop Medical Projects Ltd Liquid drug delivery devices for use with syringe having widened distal tip
DE102007046951B3 (de) 2007-10-01 2009-02-26 B. Braun Melsungen Ag Vorrichtung zum Einführen eines Medikaments in einen Infusionsbehälter
USD616090S1 (en) 2007-10-29 2010-05-18 Daikyo Seiko, Ltd. Sealing device for medicine container or medical apparatus
WO2009060419A2 (en) 2007-11-08 2009-05-14 Elcam Medical A.C.A..L. Ltd Vial adaptor and manufacturing method therfor
DE102007061346A1 (de) 2007-12-17 2009-06-18 Bayer Schering Pharma Aktiengesellschaft Spike mit zwei Dornen
US9039673B2 (en) 2008-01-09 2015-05-26 Novartis Ag Unitary withdrawal spike unit suitable for factory fitting
US8287496B2 (en) 2008-01-17 2012-10-16 Custom Medical Applications, Inc. Flow elements for use with flexible spinal needles, needle assemblies and methods therefor
IL188975A0 (en) 2008-01-23 2008-11-03 Medimop Medical Projects Ltd Fluid control device with stopper
CA2715894C (en) 2008-02-18 2014-10-14 Icu Medical, Inc. Vial adaptor
FR2927533B1 (fr) 2008-02-18 2011-02-11 P2A Medical Capuchon de transfert securise
DE102008002800A1 (de) 2008-03-10 2009-09-24 Süddeutsche Feinmechanik GmbH Mischvorrichtung
EP2271387B1 (en) 2008-04-01 2016-06-15 Yukon Medical, LLC Dual container fluid transfer device
US20090267011A1 (en) 2008-04-23 2009-10-29 Jason Hatton Dispensing valve assembly
FR2931363B1 (fr) 2008-05-23 2010-06-25 Vygon Connecteur pour circuit de liquide, notamment a usage medical et utilisation d'un tel connecteur
US8075550B2 (en) 2008-07-01 2011-12-13 Carmel Pharma Ab Piercing member protection device
US7967785B2 (en) 2008-07-14 2011-06-28 Nipro Healthcare Systems, Llc Insulin reservoir detection via magnetic switching
USD595421S1 (en) 2008-07-18 2009-06-30 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595420S1 (en) 2008-07-18 2009-06-30 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595863S1 (en) 2008-07-18 2009-07-07 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595862S1 (en) 2008-07-18 2009-07-07 Hitachi High-Technologies Corporation Adapter for a sample rack
CN104127318A (zh) 2008-08-22 2014-11-05 斯尔科生物科学公司 流体管理装置和方法
US8480645B1 (en) 2008-08-22 2013-07-09 Sambhu N. Choudhury Multi-dose device for insertion into a vial and method of using the same
JP5854836B2 (ja) 2008-08-30 2016-02-09 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング カートリッジ及びそのための針システム
US8523837B2 (en) 2008-10-14 2013-09-03 Mead Johnson Nutrition Company Nutritive substance delivery container
US7762524B2 (en) 2008-10-20 2010-07-27 Baxter International Inc. Barrier assembly for use with needleless connector
CA2780712A1 (en) 2008-11-12 2010-05-20 British Columbia Cancer Agency Branch Vial handling and injection safety systems and connectors
EP2351548B1 (en) 2008-11-21 2016-01-27 Terumo Kabushiki Kaisha Connector
CN102196798B (zh) 2008-11-25 2014-04-09 株式会社Jms 连接器
WO2010061743A1 (ja) 2008-11-25 2010-06-03 株式会社ジェイ・エム・エス コネクタ
US20100160889A1 (en) 2008-12-22 2010-06-24 Baxter International Inc. Vial access spike assembly
US8512309B2 (en) 2009-01-15 2013-08-20 Teva Medical Ltd. Vial adapter element
US8123736B2 (en) 2009-02-10 2012-02-28 Kraushaar Timothy Y Cap adapters for medicament vial and associated methods
US8012132B2 (en) 2009-02-24 2011-09-06 Becton, Dickinson And Company Luer-snap connection and luer-snap syringe
USD608900S1 (en) 2009-03-06 2010-01-26 Csp Technologies, Inc. Identification component for a vial
US8864725B2 (en) 2009-03-17 2014-10-21 Baxter Corporation Englewood Hazardous drug handling system, apparatus and method
USD641080S1 (en) 2009-03-31 2011-07-05 Medimop Medical Projects Ltd. Medical device having syringe port with locking mechanism
USD634007S1 (en) 2009-03-31 2011-03-08 Medimop Medical Projects Ltd. Needleless additive control valve
US8182452B2 (en) 2009-04-06 2012-05-22 Carefusion 303, Inc. Closed male luer device for use with needleless access devices
EP3124007A1 (en) 2009-04-14 2017-02-01 Yukon Medical, LLC Fluid transfer device
US7963939B2 (en) 2009-04-24 2011-06-21 Thomas Chun Syringe having extended blending path
DE202009011019U1 (de) 2009-07-01 2010-12-02 Süddeutsche Feinmechanik GmbH Anordnung zum Entnehmen eines Mediums aus einem Fläschchen
EP2448614B1 (en) 2009-07-01 2018-10-10 Fresenius Medical Care Holdings, Inc. Drug delivery devices and related systems and methods
USD616984S1 (en) 2009-07-02 2010-06-01 Medimop Medical Projects Ltd. Vial adapter having side windows
IL199767A0 (en) 2009-07-09 2010-04-15 Medimop Medical Projects Ltd Medical device for use with cartridge and vial
JP5333850B2 (ja) 2009-07-15 2013-11-06 ニプロ株式会社 連結器具
USD627216S1 (en) 2009-07-21 2010-11-16 The United States Of America As Represented By The Director, National Security Agency Tamper cup seal
US9149624B2 (en) 2009-09-02 2015-10-06 Carefusion 303, Inc. Disinfecting male luer connector caps
USD630732S1 (en) 2009-09-29 2011-01-11 Medimop Medical Projects Ltd. Vial adapter with female connector
IL201323A0 (en) 2009-10-01 2010-05-31 Medimop Medical Projects Ltd Fluid transfer device for assembling a vial with pre-attached female connector
WO2011050333A1 (en) 2009-10-23 2011-04-28 Amgen Inc. Vial adapter and system
IL202070A0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Inline liquid drug medical device
IL202069A0 (en) * 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Fluid transfer device with sealing arrangement
US8480646B2 (en) 2009-11-20 2013-07-09 Carmel Pharma Ab Medical device connector
USD637713S1 (en) 2009-11-20 2011-05-10 Carmel Pharma Ab Medical device adaptor
DK2501356T3 (da) 2009-12-23 2014-04-28 Medimop Medical Projects Ltd Medicinsk apparatur og engangssæt omfattende strømningsstyrende indretning til anvendelse dermed til at rekonstituere og indgive en væskeformig medikamentdosering
WO2011088471A1 (en) 2010-01-15 2011-07-21 Bayer Healthcare Llc Device
WO2011101651A1 (en) 2010-01-19 2011-08-25 Cambridge Enterprise Limited Apparatus and methods
EP2361599A1 (de) 2010-02-22 2011-08-31 Fresenius Kabi Deutschland GmbH Vorrichtung zum Zuführen oder Entnehmen einer Flüssigkeit in ein oder aus einem Behältnis
BR112012020829B1 (pt) 2010-02-24 2020-04-14 Medimop Medical Projects Ltd dispositivo de transferência de droga líquida para usar com um frasco medicinal
EP2545950A4 (en) 2010-03-10 2014-05-07 Terumo Corp Injection needle assembly and drug injection device
USD644104S1 (en) 2010-04-15 2011-08-30 Sumitomo Rubber Industries, Ltd. Rubber stopper for vial
US8702674B2 (en) 2010-04-27 2014-04-22 Crisi Medical Systems, Inc. Medication and identification information transfer apparatus
USD655017S1 (en) 2010-06-17 2012-02-28 Yukon Medical, Llc Shroud
JP5888234B2 (ja) 2010-06-30 2016-03-16 ニプロ株式会社 噴霧器
US8721627B2 (en) 2010-07-22 2014-05-13 Carefusion 303, Inc. Needleless valve infection prevention and pre-opening device
USD654166S1 (en) 2010-08-06 2012-02-14 Neomed, Inc. Enteral connector
KR101899449B1 (ko) 2010-08-25 2018-09-17 박스앨타 게엠베하 사용자 재구성을 용이하게 하는 어셈블리
US20120078214A1 (en) 2010-09-28 2012-03-29 Tyco Healthcare Group Lp Vial transfer needle assembly
USD669980S1 (en) 2010-10-15 2012-10-30 Medimop Medical Projects Ltd. Vented vial adapter
IL209102A0 (en) 2010-11-04 2011-01-31 Medimop Medical Projects Ltd Inline liquid drug medical device with handle operated flow control member
IL209290A0 (en) 2010-11-14 2011-01-31 Medimop Medical Projects Ltd Inline liquid drug medical device having rotary flow control member
EP2462913A1 (en) 2010-12-10 2012-06-13 Fresenius Medical Care Deutschland GmbH Insert and vial for the infusion of liquids
JP5670242B2 (ja) 2011-03-29 2015-02-18 テルモ株式会社 薬剤調製用具
USD657461S1 (en) 2011-04-04 2012-04-10 Cook Medical Technologies Llc Biopsy needle tip
US20120265163A1 (en) 2011-04-14 2012-10-18 Marc Bunjiun Cheng Coupling system to transfer material between containers
IL212420A0 (en) 2011-04-17 2011-06-30 Medimop Medical Projects Ltd Liquid drug transfer assembly
USD690418S1 (en) 2011-05-02 2013-09-24 Carmel Pharma Ab Medical device
WO2012150587A1 (en) 2011-05-03 2012-11-08 Sabiedriba Ar Ierobezotu Atbildibu "Sdmd" Vial adaptor
FR2975896B1 (fr) 2011-06-06 2014-06-06 Biocorp Rech Et Dev Dispositif de connexion entre un recipient et un contenant, procede d'assemblage et d'utilisation d'un tel dispositif
WO2012174464A2 (en) 2011-06-17 2012-12-20 Tautona Group Lp Needle for delivery of dermal filler threads
USD673673S1 (en) 2011-07-11 2013-01-01 Hsien-Tsung Wang Transparent Y-type of intravenous drip infusion set
USD674084S1 (en) 2011-07-21 2013-01-08 Mtp Medical Technical Promotion Gmbh Puncture cannula
USD681230S1 (en) 2011-09-08 2013-04-30 Yukon Medical, Llc Shroud
IL215699A0 (en) 2011-10-11 2011-12-29 Medimop Medical Projects Ltd Liquid drug reconstitution assemblage for use with iv bag and drug vial
USD711516S1 (en) 2011-12-09 2014-08-19 John Guest International Limited Fluid connector
USD720452S1 (en) 2011-12-15 2014-12-30 Mark Jordan Syringe connection hub
AU344164S (en) 2012-02-02 2012-09-04 Terumo Corp Safety device for indwelling needle
USD720451S1 (en) 2012-02-13 2014-12-30 Medimop Medical Projects Ltd. Liquid drug transfer assembly
USD674088S1 (en) 2012-02-13 2013-01-08 Medimop Medical Projects Ltd. Vial adapter
JP2015508690A (ja) 2012-02-29 2015-03-23 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 容器から薬剤を１回だけ引き出すための引出しデバイス
US10206854B2 (en) 2012-03-05 2019-02-19 Becton, Dickinson And Company Transfer set with floating needle for drug reconstitution
US20130253448A1 (en) 2012-03-09 2013-09-26 Steven Baron Hypodermic Needle With Multiple Dispersement Openings
IL219065A0 (en) 2012-04-05 2012-07-31 Medimop Medical Projects Ltd Fluid transfer device with manual operated cartridge release arrangement
IL219222A0 (en) 2012-04-17 2012-07-31 Medimop Medical Projects Ltd Quick release vial adapter
ITRM20120169A1 (it) 2012-04-19 2013-10-20 Consiglio Nazionale Ricerche Dispositivo di rilascio di specie chimiche a controllo ottico
IL221634A0 (en) 2012-08-26 2012-12-31 Medimop Medical Projects Ltd Universal drug vial adapter
IL221635A0 (en) 2012-08-26 2012-12-31 Medimop Medical Projects Ltd Drug vial mixing and transfer device for use with iv bag and drug vial
EP2922590B1 (en) 2012-11-21 2020-02-05 Amgen Inc. Drug delivery device
CA2892760C (en) 2012-11-30 2017-07-11 Becton Dickinson and Company Limited Infusion adapter for drug transfer assembly
USD717406S1 (en) 2012-12-10 2014-11-11 Enviro Water Solutions, Inc. Backwash fitting
USD714935S1 (en) 2013-01-10 2014-10-07 Fuso Pharmaeutical Industries, Ltd. Adapter for connecting a needle to a syringe
USD733291S1 (en) 2013-01-15 2015-06-30 Hsien-Tsung Wang Depressible plug for vial
USD732664S1 (en) 2013-02-25 2015-06-23 B. Braun Melsungen Ag Proximal catheter hub body
USD738494S1 (en) 2013-03-05 2015-09-08 Ikashmore Pty Ltd Blood collection safety device
USD733292S1 (en) 2013-03-10 2015-06-30 Rocomp Global, Llc Energy guide
US9308020B2 (en) 2013-03-14 2016-04-12 Cook Medical Technologies Llc Tri-fluted vascular access needle
USD720850S1 (en) 2013-03-15 2015-01-06 Sanovas, Inc. Catheter hub
USD733293S1 (en) 2013-03-15 2015-06-30 Rocomp Global, Llc Energy guide
GB201307385D0 (en) 2013-04-24 2013-06-05 Star Syringe Ltd Syringes
WO2015042517A2 (en) 2013-09-23 2015-03-26 Becton, Dickinson And Company, Ltd. Piercing member for container access device
AU353353S (en) 2013-10-02 2014-01-21 Terumo Corp Medical syringe
US20150305770A1 (en) 2014-03-12 2015-10-29 Epicardial Frontiers, LLC System and method of image guided pericardial procedures including pericardioscopy, pericardial ablation, pericardial material delivery, pericardial tissue grasping and manipulation, pericardial lead placement, and pericardial surgical fastener placement
USD750235S1 (en) 2014-03-19 2016-02-23 ERBE-USA, Inc. Endoscope connector
CN107073211B (zh) 2014-08-14 2021-01-05 韦贝尔Cds公司 具有可选择的流动通道和密封部的注射器
JP6368603B2 (ja) 2014-09-25 2018-08-01 テルモ株式会社 消毒キャップ

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871463A (en) * 1988-08-23 1989-10-03 Sepratech Vertical reaction vessel
US20020193733A1 (en) * 1999-11-19 2002-12-19 Taylor Michael A. In-line iv drug delivery pack with controllable dilution
US20030068354A1 (en) * 2001-10-05 2003-04-10 Oscar-Werner Reif Genetic vaccination device and process for forming an injection therefor
CN1744871A (zh) * 2003-02-05 2006-03-08 阿卡多福塔公司 用于临时制备单次使用量的无菌流体的装置和方法
JP2006061421A (ja) * 2004-08-26 2006-03-09 Bio Media Co Ltd 薬剤収容ユニット
CN101378727A (zh) * 2005-11-21 2009-03-04 剑桥生物稳定性有限公司 用于向患者供给药物的药用装置
WO2007101772A1 (en) * 2006-03-07 2007-09-13 Novo Nordisk A/S A drug mixing device
CN102711712A (zh) * 2010-02-24 2012-10-03 麦迪麦珀医疗工程有限公司 具有通风布置的流体转移组合件
WO2012004784A1 (en) * 2010-07-04 2012-01-12 Medimop Medical Projects Ltd Vial adapter with syringe stabilizer

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109152699A (zh) * 2016-05-24 2019-01-04 西部制药服务以色列有限公司 包括相同的成对的小瓶转接器的双瓶转接器组合件
CN109152699B (zh) * 2016-05-24 2020-03-10 西部制药服务以色列有限公司 包括相同的成对的小瓶转接器的双瓶转接器组合件
CN110996877A (zh) * 2017-08-10 2020-04-10 巴克斯特国际公司 以适度剂量供给药物的重构装置、系统和方法
CN109432554A (zh) * 2018-11-19 2019-03-08 北京快舒尔医疗技术有限公司 无针注射器的注射头、注射头组件和无针注射器
WO2022047962A1 (zh) * 2020-09-04 2022-03-10 汪祥海 一种液体注入器转接头

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