CN1037336A - 新型4-氯-3-氨磺酰苯甲酰肼-制备方法，含此化合物的药物组分及其医疗用途 - Google Patents

新型4-氯-3-氨磺酰苯甲酰肼-制备方法，含此化合物的药物组分及其医疗用途 Download PDF

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Publication number
CN1037336A
CN1037336A CN88108996A CN88108996A CN1037336A CN 1037336 A CN1037336 A CN 1037336A CN 88108996 A CN88108996 A CN 88108996A CN 88108996 A CN88108996 A CN 88108996A CN 1037336 A CN1037336 A CN 1037336A
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CN
China
Prior art keywords
general formula
compound
amino
chloro
benzoyl
Prior art date
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Pending
Application number
CN88108996A
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English (en)
Chinese (zh)
Inventor
恩德雷·帕洛斯
得索·科布恩斯
厄泽伯特·莫尔纳
伊达·肖沃布达
拉斯兹·哈辛
吉奥吉·西蒙
桑多尔·弗艾
维拉·格根利
卡塔琳·马玛奥斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of CN1037336A publication Critical patent/CN1037336A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/22—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN88108996A 1987-12-30 1988-12-30 新型4-氯-3-氨磺酰苯甲酰肼-制备方法，含此化合物的药物组分及其医疗用途 Pending CN1037336A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU876131A HU207051B (en) 1987-12-30 1987-12-30 Process for producing 4-chloro-3-sulfamoylbenzoic acid hydrazides and pharmaceutical compositions comprising such compounds
HU6131/87 1987-12-30

Publications (1)

Publication Number Publication Date
CN1037336A true CN1037336A (zh) 1989-11-22

Family

ID=10971250

Family Applications (1)

Application Number Title Priority Date Filing Date
CN88108996A Pending CN1037336A (zh) 1987-12-30 1988-12-30 新型4-氯-3-氨磺酰苯甲酰肼-制备方法，含此化合物的药物组分及其医疗用途

Country Status (27)

Country Link
US (1) US4916149A (es)
EP (1) EP0324988B1 (es)
JP (1) JPH01213269A (es)
CN (1) CN1037336A (es)
AT (1) ATE75467T1 (es)
AU (1) AU609682B2 (es)
CA (1) CA1332739C (es)
CS (1) CS277585B6 (es)
DD (1) DD283383A5 (es)
DE (1) DE3870601D1 (es)
DK (1) DK727488A (es)
ES (1) ES2034149T3 (es)
FI (1) FI886045A (es)
GR (1) GR3004471T3 (es)
HU (1) HU207051B (es)
IE (1) IE63246B1 (es)
IL (1) IL88735A (es)
NO (1) NO172285C (es)
NZ (1) NZ227481A (es)
PH (1) PH25739A (es)
PL (2) PL157971B1 (es)
PT (1) PT89368B (es)
RU (2) RU1838303C (es)
SU (1) SU1736339A3 (es)
UA (1) UA19123A (es)
YU (1) YU47125B (es)
ZA (1) ZA889729B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100374424C (zh) * 2001-07-06 2008-03-12 拜尔农作物科学股份公司 杂环酰胺衍生物和其用途

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0581904T3 (da) * 1991-04-01 1997-12-29 Univ Duke Fremgangsmåde til inhibering af fibrose
FR2708608B1 (fr) * 1993-07-30 1995-10-27 Sanofi Sa Dérivés de N-sulfonylbenzimidazolone, leur préparation, les compositions pharmaceutiques en contenant.
DE102005002130A1 (de) * 2005-01-17 2006-07-27 Sanofi-Aventis Deutschland Gmbh Substituierte N-Aminomethylensulfonamide, ihre Herstellung und Verwendung als Arzneimittel

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1122541B (de) * 1959-12-28 1962-01-25 Hoechst Ag Verfahren zur Herstellung von Sulfamyl-anthranilsaeuren
DE1158927B (de) * 1961-09-15 1963-12-12 Werner Rahms Grubenstempel
DE2144908C2 (de) * 1971-09-08 1982-12-09 Hoechst Ag, 6000 Frankfurt 5-(3- oder 4-Aminobenzolsulfonylamino)-benzimidazolone-(2) und Verfahren zu ihrer Herstellung
BE793718A (fr) * 1972-01-07 1973-07-05 Merck & Co Inc Aminobenzimidazoles
DE2247828A1 (de) * 1972-09-29 1974-04-04 Hoechst Ag Sulfamoyl-anthranilsaeuren und verfahren zu ihrer herstellung
US4420487A (en) * 1978-04-10 1983-12-13 The Purdue Frederick Company Diuretic and antihypertensive benzimidazoles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100374424C (zh) * 2001-07-06 2008-03-12 拜尔农作物科学股份公司 杂环酰胺衍生物和其用途

Also Published As

Publication number Publication date
HUT56550A (en) 1991-09-30
RU1838303C (ru) 1993-08-30
AU2763188A (en) 1989-07-13
CS910888A3 (en) 1992-09-16
YU47125B (sh) 1994-12-28
DK727488A (da) 1989-07-01
GR3004471T3 (es) 1993-03-31
NO172285B (no) 1993-03-22
IE883892L (en) 1989-06-30
IE63246B1 (en) 1995-04-05
IL88735A0 (en) 1989-07-31
RU1830064C (ru) 1993-07-23
CA1332739C (en) 1994-10-25
PL157971B1 (pl) 1992-07-31
FI886045A (fi) 1989-07-01
IL88735A (en) 1992-12-01
US4916149A (en) 1990-04-10
PL158049B1 (pl) 1992-07-31
NO172285C (no) 1993-06-30
DE3870601D1 (de) 1992-06-04
ES2034149T3 (es) 1993-04-01
JPH01213269A (ja) 1989-08-28
PT89368B (pt) 1993-08-31
HU207051B (en) 1993-03-01
DK727488D0 (da) 1988-12-29
PT89368A (pt) 1989-12-29
PH25739A (en) 1991-10-18
DD283383A5 (de) 1990-10-10
SU1736339A3 (ru) 1992-05-23
EP0324988A1 (de) 1989-07-26
CS277585B6 (en) 1993-03-17
UA19123A (uk) 1997-12-25
NZ227481A (en) 1990-11-27
NO885830D0 (no) 1988-12-30
ZA889729B (en) 1989-10-25
EP0324988B1 (de) 1992-04-29
YU240188A (en) 1990-10-31
NO885830L (no) 1989-07-03
AU609682B2 (en) 1991-05-02
ATE75467T1 (de) 1992-05-15
PL276889A1 (en) 1990-04-02

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