CN102803293B - 治疗骨丢失相关疾病的siglec 15抗体 - Google Patents

治疗骨丢失相关疾病的siglec 15抗体 Download PDF

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Publication number
CN102803293B
CN102803293B CN201080053103.4A CN201080053103A CN102803293B CN 102803293 B CN102803293 B CN 102803293B CN 201080053103 A CN201080053103 A CN 201080053103A CN 102803293 B CN102803293 B CN 102803293B
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seq
antibody
antigen
amino acid
binding fragment
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CN102803293A (zh
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G·B·特雷姆勃雷
M·菲利昂
M·司徒伯雷
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Alethia Biotherapeutics Inc
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Alethia Biotherapeutics Inc
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C—CHEMISTRY; METALLURGY
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CN201080053103.4A 2009-10-06 2010-10-06 治疗骨丢失相关疾病的siglec 15抗体 Expired - Fee Related CN102803293B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610363038.4A CN106046160A (zh) 2009-10-06 2010-10-06 治疗骨丢失相关疾病的 siglec 15 抗体

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24896009P 2009-10-06 2009-10-06
US61/248,960 2009-10-06
US12/580,943 2009-10-16
US12/580,943 US8168181B2 (en) 2006-02-13 2009-10-16 Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
PCT/CA2010/001586 WO2011041894A1 (en) 2009-10-06 2010-10-06 Siglec 15 antibodies in treating bone loss-related disease

Related Child Applications (1)

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CN201610363038.4A Division CN106046160A (zh) 2009-10-06 2010-10-06 治疗骨丢失相关疾病的 siglec 15 抗体

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CN102803293A CN102803293A (zh) 2012-11-28
CN102803293B true CN102803293B (zh) 2016-05-18

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CN201080053103.4A Expired - Fee Related CN102803293B (zh) 2009-10-06 2010-10-06 治疗骨丢失相关疾病的siglec 15抗体
CN201610363038.4A Pending CN106046160A (zh) 2009-10-06 2010-10-06 治疗骨丢失相关疾病的 siglec 15 抗体

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US (6) US8168181B2 (enExample)
EP (1) EP2486060A4 (enExample)
JP (2) JP5855569B2 (enExample)
KR (1) KR20120086297A (enExample)
CN (2) CN102803293B (enExample)
AU (2) AU2010305281C1 (enExample)
BR (1) BR112012007860A2 (enExample)
CA (2) CA2775793C (enExample)
IL (1) IL218985A0 (enExample)
MX (1) MX2012004084A (enExample)
NZ (1) NZ599193A (enExample)
RU (1) RU2596392C2 (enExample)
WO (1) WO2011041894A1 (enExample)

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US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
WO2007093042A1 (en) 2006-02-13 2007-08-23 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in the process of bone remodeling
MX2010003394A (es) * 2007-09-28 2010-04-09 Daiichi Sankyo Co Ltd Derivado de gamma-aminoacido biciclico.
EP2206727B1 (en) 2007-10-11 2015-04-01 Daiichi Sankyo Company, Limited ANTIBODY TARGETING OSTEOCLAST-RELATED PROTEIN Siglec-15
ES2635354T3 (es) 2009-03-26 2017-10-03 Daiichi Sankyo Company, Limited Procedimiento de producción de un derivado de ácido gamma-amino bicíclico
NZ593550A (en) 2009-04-09 2013-11-29 Daiichi Sankyo Co Ltd ANTI-Siglec-15 ANTIBODY
CN103237813A (zh) 2010-10-05 2013-08-07 第一三共株式会社 靶向破骨细胞相关蛋白涎免凝集素-15的抗体
JP6216317B2 (ja) * 2011-09-09 2017-10-18 メディミューン リミテッド 抗Ｓｉｇｌｅｃ−１５抗体およびその使用
US9003797B2 (en) * 2011-11-02 2015-04-14 E L Du Pont De Nemours And Company Use of compositions comprising 1,1,1,2,3-pentafluoropropane and optionally Z-1,1,1,4,4,4-hexafluoro-2-butene in power cycles
KR20140138215A (ko) * 2012-03-30 2014-12-03 다이이찌 산쿄 가부시키가이샤 신규 항 Ｓｉｇｌｅｃ-15 항체
JP6059205B2 (ja) * 2012-03-30 2017-01-11 第一三共株式会社 ＣＤＲ改変抗Ｓｉｇｌｅｃ−１５抗体
CA2928851A1 (en) * 2012-07-19 2014-01-23 Alethia Biotherapeutics Inc. Anti-siglec-15 antibodies
RU2656153C1 (ru) * 2013-12-20 2018-05-31 Девелопмент Сентер Фор Байотекнолоджи Антитела, специфичные к альфа-энолазе, и способы применения в противоопухолевой терапии
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