DE602006014519D1 - Peptide zur transglutaminase-hemmung - Google Patents
Peptide zur transglutaminase-hemmungInfo
- Publication number
- DE602006014519D1 DE602006014519D1 DE602006014519T DE602006014519T DE602006014519D1 DE 602006014519 D1 DE602006014519 D1 DE 602006014519D1 DE 602006014519 T DE602006014519 T DE 602006014519T DE 602006014519 T DE602006014519 T DE 602006014519T DE 602006014519 D1 DE602006014519 D1 DE 602006014519D1
- Authority
- DE
- Germany
- Prior art keywords
- transglutaminase
- cancers
- peptides
- disclosed
- inflammatory diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Toxicology (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Heart & Thoracic Surgery (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20050124420 | 2005-12-16 | ||
PCT/KR2006/004089 WO2007069817A1 (en) | 2005-12-16 | 2006-10-11 | Peptides for inhibiting transglutaminase |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006014519D1 true DE602006014519D1 (de) | 2010-07-08 |
Family
ID=38163103
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006014519T Active DE602006014519D1 (de) | 2005-12-16 | 2006-10-11 | Peptide zur transglutaminase-hemmung |
Country Status (8)
Country | Link |
---|---|
US (1) | US8754033B2 (de) |
EP (1) | EP1866329B1 (de) |
JP (1) | JP5006336B2 (de) |
KR (1) | KR100838715B1 (de) |
CN (1) | CN101180311A (de) |
AT (1) | ATE469168T1 (de) |
DE (1) | DE602006014519D1 (de) |
WO (1) | WO2007069817A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2822302A1 (en) | 2006-02-13 | 2007-08-23 | Alethia Biotherapeutics Inc. | Methods of impairing osteoclast differentiation |
US8168181B2 (en) | 2006-02-13 | 2012-05-01 | Alethia Biotherapeutics, Inc. | Methods of impairing osteoclast differentiation using antibodies that bind siglec-15 |
EP2408471B1 (de) * | 2009-03-19 | 2015-06-24 | Queensland University Of Technology | Zielmoleküle für wachstungsfaktorsignalwege und therapieverfahren |
MX2015000863A (es) | 2012-07-19 | 2016-05-05 | Alethia Biotherapeutics Inc | Anticuerpos anti-siglec-15. |
GB201318182D0 (en) * | 2013-10-14 | 2013-11-27 | Univ Nottingham Trent | Inhibitor peptides |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2859270B2 (ja) * | 1987-06-11 | 1999-02-17 | 旭光学工業株式会社 | カメラの視線方向検出装置 |
US5885982A (en) | 1992-03-23 | 1999-03-23 | Dolynchuk; Kenneth Nicholis | Use of transglutaminase inhibitor for the treatment of scar tissue |
EP1135504B1 (de) | 1998-12-10 | 2011-02-23 | Signal Pharmaceuticals LLC | Menschliche ubiqutin ligase e3. verwendung für die modulation von nf-kappa b |
WO2001040521A2 (en) * | 1999-11-30 | 2001-06-07 | Curagen Corporation | Nucleic acids containing single nucleotide polymorphisms and methods of use thereof |
US20030096243A1 (en) * | 2000-09-28 | 2003-05-22 | Busa William Brian | Methods and reagents for live-cell gene expression quantification |
JP2005507650A (ja) * | 2001-08-01 | 2005-03-24 | セロミックス インコーポレイテッド | 新規融合タンパク質及び分子結合に関するアッセイ |
JP2008507995A (ja) * | 2004-08-02 | 2008-03-21 | セルーメン、インコーポレイテッド | 細胞内での分子相互作用の検出方法 |
-
2006
- 2006-10-11 EP EP06799169A patent/EP1866329B1/de not_active Not-in-force
- 2006-10-11 CN CNA200680011298XA patent/CN101180311A/zh active Pending
- 2006-10-11 US US11/918,340 patent/US8754033B2/en not_active Expired - Fee Related
- 2006-10-11 KR KR1020060098921A patent/KR100838715B1/ko not_active IP Right Cessation
- 2006-10-11 JP JP2008545475A patent/JP5006336B2/ja not_active Expired - Fee Related
- 2006-10-11 AT AT06799169T patent/ATE469168T1/de not_active IP Right Cessation
- 2006-10-11 WO PCT/KR2006/004089 patent/WO2007069817A1/en active Application Filing
- 2006-10-11 DE DE602006014519T patent/DE602006014519D1/de active Active
Also Published As
Publication number | Publication date |
---|---|
US20090197812A1 (en) | 2009-08-06 |
CN101180311A (zh) | 2008-05-14 |
JP5006336B2 (ja) | 2012-08-22 |
EP1866329A1 (de) | 2007-12-19 |
KR100838715B1 (ko) | 2008-06-16 |
US8754033B2 (en) | 2014-06-17 |
WO2007069817A1 (en) | 2007-06-21 |
JP2009519323A (ja) | 2009-05-14 |
EP1866329B1 (de) | 2010-05-26 |
EP1866329A4 (de) | 2008-05-21 |
KR20070064379A (ko) | 2007-06-20 |
ATE469168T1 (de) | 2010-06-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA200809250B (en) | Tetrahydropyrrolopyrimidinediones and their use as human neutrophil elastase inhibitors | |
MX2009000285A (es) | Piperidinas sustituidas que incrementan la actividad de p53 y usos de las mismas. | |
HK1135103A1 (en) | Dihydropyridine derivatives useful as protein kinase inhibitors | |
WO2003089456A3 (en) | Peptide inhibitors of protein kinase c | |
EA200900613A1 (ru) | Спирокетоновые ингибиторы ацетил-коа-карбоксилаз | |
WO2006091395A3 (en) | Inhibitors of akt activity | |
TW200736253A (en) | Pyridopyrazine derivatives and their use | |
TW200736229A (en) | Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors | |
GEP20115283B (en) | Pyrrolopyrimidine compounds and their uses | |
DE602007005120D1 (de) | 2-pyridonderivate zur behandlung von krankheiten oder leiden, bei denen eine inhibierung der aktivität der neutrophilen elastase von nutzen ist | |
IN2005KO00312A (de) | ||
WO2007087068A3 (en) | Inhibitors of tyrosine kinases and uses thereof | |
MXPA05010711A (es) | Compuestos y composiciones novedosos como inhibidores de proteina-quinasa. | |
NO20060398L (no) | Anvendelse av en kombinasjon av en epidermal vekstfaktor reseptor kinase inhibitor og cytotoksiske midler for behandling og hemming av kreft | |
EA200800006A1 (ru) | Триазолопиридины в качестве ингибиторов 11-бета-гидроксистероиддегидрогеназы типа i | |
ATE520668T1 (de) | Sigmarezeptor-inhibitoren | |
WO2006110638A3 (en) | Inhibitors of akt activity | |
MX2008012479A (es) | Tratamiento de enfermedades neurodegenerativas. | |
UA84954C2 (ru) | Конденсированные пиримидоны, пригодные для лечения и профилактики злокачественного новообразования | |
CL2008000021A1 (es) | Compuestos derivados de 2,4-dianilinopirimidinas, inhibidores de proteinas cinasas; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento o prevencion de enfermedades inflamatorias, diabetes y cancer. | |
WO2007016338A3 (en) | Use of chk2 kinase inhibitors for cancer treatment | |
MX2008008556A (es) | Derivados de triterpenoquinonas y triterpenofenoles y su aplicacion para el tratamiento de tumores y enfermedades parasitarias. | |
WO2009041787A3 (en) | Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper nigrum for the prevention and treatment of inflammatory disease | |
WO2007121124A3 (en) | Hcv inhibitors comprising beta amino acids and their uses | |
ATE469168T1 (de) | Peptide zur transglutaminase-hemmung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |