WO2009041787A3 - Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper nigrum for the prevention and treatment of inflammatory disease - Google Patents

Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper nigrum for the prevention and treatment of inflammatory disease Download PDF

Info

Publication number
WO2009041787A3
WO2009041787A3 PCT/KR2008/005723 KR2008005723W WO2009041787A3 WO 2009041787 A3 WO2009041787 A3 WO 2009041787A3 KR 2008005723 W KR2008005723 W KR 2008005723W WO 2009041787 A3 WO2009041787 A3 WO 2009041787A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
piper nigrum
inhibitors
prevention
treatment
Prior art date
Application number
PCT/KR2008/005723
Other languages
French (fr)
Other versions
WO2009041787A2 (en
Inventor
Mun-Chual Rho
Young-Kook Kim
Hyun-Sun Lee
Chang-Duk Jun
Koanhoi Kim
Seung-Woong Lee
Jung Ho Choi
Jae Jun Song
Original Assignee
Korea Res Inst Of Bioscience
Mun-Chual Rho
Young-Kook Kim
Hyun-Sun Lee
Chang-Duk Jun
Koanhoi Kim
Seung-Woong Lee
Jung Ho Choi
Jae Jun Song
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Res Inst Of Bioscience, Mun-Chual Rho, Young-Kook Kim, Hyun-Sun Lee, Chang-Duk Jun, Koanhoi Kim, Seung-Woong Lee, Jung Ho Choi, Jae Jun Song filed Critical Korea Res Inst Of Bioscience
Publication of WO2009041787A2 publication Critical patent/WO2009041787A2/en
Publication of WO2009041787A3 publication Critical patent/WO2009041787A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a Piper nigrum extract having prophylactic and therapeutic effects on inflammatory or infectious diseases, and to amide compounds isolated therefrom. In addition, the present invention relates to a pharmaceutical composition for preventing or treating inflammatory or infectious diseases, comprising the Piper nigrum extract or amide compound isolated therefrom as an active ingredient.
PCT/KR2008/005723 2007-09-28 2008-09-26 Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper nigrum for the prevention and treatment of inflammatory disease WO2009041787A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020070097968A KR100954866B1 (en) 2007-09-28 2007-09-28 Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from Piper nigrum for the prevention and treatment of inflammatory disease
KR10-2007-0097968 2007-09-28

Publications (2)

Publication Number Publication Date
WO2009041787A2 WO2009041787A2 (en) 2009-04-02
WO2009041787A3 true WO2009041787A3 (en) 2009-05-14

Family

ID=40512030

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2008/005723 WO2009041787A2 (en) 2007-09-28 2008-09-26 Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper nigrum for the prevention and treatment of inflammatory disease

Country Status (2)

Country Link
KR (1) KR100954866B1 (en)
WO (1) WO2009041787A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010136221A1 (en) * 2009-05-29 2010-12-02 Dr. August Wolff Gmbh & Co. Kg Arzneimittel Dodeca-2e,4e-diene amides and their use as medicaments and cosmetics
FR2957259B1 (en) * 2010-03-12 2012-04-27 Silab Sa ACTIVE REFINING COSMETIC PRINCIPLE FROM PIPER NIGRUM, COSMETIC COMPOSITIONS INCLUDING THE SAME AND USE THEREOF
WO2012091685A1 (en) * 2010-12-30 2012-07-05 Anandechakunkorn Siridechpong Thai herb modified traditional drugs
CA2738357C (en) * 2011-04-07 2019-08-06 Amerisciences, Lp Methods and compositions to promote ocular health
KR20140057040A (en) * 2012-11-02 2014-05-12 연세대학교 산학협력단 Compositions for improving skin aging comprising piperine compounds as active ingredients
KR101431987B1 (en) * 2013-09-12 2014-08-22 중앙대학교 산학협력단 Composition for treating contact dermatitis comprising pellitorine as an active ingredient
CN104587070A (en) * 2015-02-25 2015-05-06 胡运冲 Traditional Chinese medicine composition for treating wind-cold-dampness arthralgia and stasis type cervical spondylosis
KR20200078803A (en) 2018-12-21 2020-07-02 강릉원주대학교산학협력단 An anti-inflammatory or immunological enhancing composition comprising a Halocynthia aurantium tunic lipids as an active ingredient
CZ309814B6 (en) * 2022-01-04 2023-11-01 Ústav experimentální botaniky AV ČR, v. v. i Phenylpropanoid derivatives, preparations containing these derivatives and their use
CN115636801B (en) * 2022-10-26 2024-01-09 武汉润禾生物医药有限公司 Amide alkaloid and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005298429A (en) * 2004-04-14 2005-10-27 Maruzen Pharmaceut Co Ltd Vascular endothelial type nitric oxide synthase activity promoter
US7081260B2 (en) * 2002-10-29 2006-07-25 Council Of Scientific And Industrial Research α-Glucosidase inhibitors from a natural source

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7081260B2 (en) * 2002-10-29 2006-07-25 Council Of Scientific And Industrial Research α-Glucosidase inhibitors from a natural source
JP2005298429A (en) * 2004-04-14 2005-10-27 Maruzen Pharmaceut Co Ltd Vascular endothelial type nitric oxide synthase activity promoter

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ASHOK K ET AL.: "Investigation toward new lead compounds from medicinally important plants", PURE APPL. CHEM., vol. 77, no. 1, 2005, pages 25 - 40 *
JOCHEN R ET AL.: "Constituents of Chinese Piper species and their inhibitory activity on prostaglandin and leukotriene biosynthesis in vitro", J. ETHNOPHARMACOL., vol. 75, 2001, pages 133 - 139 *
SARVESH KUMAR ET AL.: "Piperine inhibits TNF- a induced adhesion of neutrophils to endothelial monolayer through suppression of NF- K B and I K B kinase activation", EUR. J. PHARMACOL., vol. 575, August 2007 (2007-08-01), pages 177 - 186 *

Also Published As

Publication number Publication date
WO2009041787A2 (en) 2009-04-02
KR100954866B1 (en) 2010-04-28
KR20090032601A (en) 2009-04-01

Similar Documents

Publication Publication Date Title
WO2009041787A3 (en) Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper nigrum for the prevention and treatment of inflammatory disease
WO2007096151A3 (en) Inhibitors of p38-kinase for treatment of pulmonary hypertension
WO2007133637A3 (en) Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
WO2009144555A8 (en) Pyrazolospiroketone acetyl-coa carboxylase inhibitors
WO2006096439A3 (en) Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases
WO2006102610A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
WO2004078712A3 (en) Isoquinoline derivatives and methods of use thereof
WO2008070129A3 (en) Compositions and methods for the treatment of inflammatory disease
WO2007019251A3 (en) Sphingosine kinase inhibitors and methods of their use
WO2007109192A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
WO2005075425A3 (en) Substituted bisarylurea derivatives as kinase inhibitors
WO2011058474A8 (en) N1-pyrazolospiroketone acetyl-coa carboxylase inhibitors
WO2007109172A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
WO2008022256A3 (en) Methods and compositions for preventing or treating age-related diseases
EA200900613A1 (en) SPIROKETONE ACETYL-COA-CARBOXYLAS INHIBITORS
WO2008148074A3 (en) Inhibitors of mtor and methods of treatment using same
WO2007109154A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
WO2009030952A3 (en) Phenylcarboxamide derivatives as inhibitors and effectors of the hedgehog pathway
WO2007106537A3 (en) Aminoquinolones as gsk-3 inhibitors
WO2007109182A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
ZA200806778B (en) N-Hydroxyacrylamide compounds
WO2006093832A3 (en) Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
WO2007123939A8 (en) Novel arylamino n-heteraryls as mek inhibitors
WO2007028022A3 (en) Novel compounds as p2x7 modulators and uses thereof
WO2007109201A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08834301

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08834301

Country of ref document: EP

Kind code of ref document: A2