CN101967150A - 螺杂环化合物及其作为治疗剂的用途 - Google Patents

螺杂环化合物及其作为治疗剂的用途 Download PDF

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Publication number
CN101967150A
CN101967150A CN2010102862777A CN201010286277A CN101967150A CN 101967150 A CN101967150 A CN 101967150A CN 2010102862777 A CN2010102862777 A CN 2010102862777A CN 201010286277 A CN201010286277 A CN 201010286277A CN 101967150 A CN101967150 A CN 101967150A
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alkyl
cyclic hydrocarbon
aryl
heterocyclic radical
aralkyl
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Chinese (zh)
Inventor
麦克海里·乔威夫
苏鲁旦·乔德亨瑞
罗伯特·法瑟
傅建民
雷杰德·坎柏
歇吉瑞·史瑞威多
玛瑞·赛德·巴哈萨德
刘世峰
孙建宇
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Xenon Pharmaceuticals Inc
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Xenon Pharmaceuticals Inc
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    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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CN2010102862777A 2005-04-11 2006-04-11 螺杂环化合物及其作为治疗剂的用途 Pending CN101967150A (zh)

Applications Claiming Priority (2)

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US67096205P 2005-04-11 2005-04-11
US60/670,962 2005-04-11

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CNA2006800118134A Pending CN101166744A (zh) 2005-04-11 2006-04-11 螺杂环化合物及其作为治疗剂的用途

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US (2) US7799798B2 (enExample)
EP (1) EP1888592B1 (enExample)
JP (1) JP2008535916A (enExample)
KR (1) KR20080007250A (enExample)
CN (2) CN101967150A (enExample)
AR (1) AR053710A1 (enExample)
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MY144968A (en) * 2005-04-11 2011-11-30 Xenon Pharmaceuticals Inc Spiro-oxindole compounds and their uses as therapeutic agents
AR053713A1 (es) * 2005-04-20 2007-05-16 Xenon Pharmaceuticals Inc Compuestos heterociclicos y sus usos como agentes terapeuticos
WO2008046082A2 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Use of heterocyclic compounds as therapeutic agents
MX2009003876A (es) 2006-10-12 2009-05-11 Xenon Pharmaceuticals Inc Uso de compuestos de espiro-oxindol como agentes terapeuticos.
WO2008046087A2 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Spiro compounds and their uses as therapeutic agents
WO2008046065A1 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Spiroheterocyclic compounds and their uses as therapeutic agents
JP2010522690A (ja) * 2006-10-12 2010-07-08 ゼノン・ファーマシューティカルズ・インコーポレイテッド 三環式スピロオキシインドール誘導体および治療薬としてのその使用
MX2009003875A (es) * 2006-10-12 2009-04-22 Xenon Pharmaceuticals Inc Derivados y compuestos relacionados de espiro(furo[3,2-c]piridina- 3,3'-indol)-2' (1'h)ona para el tratamiento de enfermedades mediadas por los canales de sodio, tal como dolor.
US20100010092A1 (en) * 2006-12-19 2010-01-14 Arless Ltd. Use of modafinil to treat restless leg syndrome
US7795228B2 (en) * 2006-12-28 2010-09-14 Theracos, Inc. Spiroheterocyclic glycosides and methods of use
US8309544B2 (en) * 2007-05-16 2012-11-13 Merck Sharp & Dohme Corp. Spiroindalones
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