PL1888592T3 - Związki spiroheterocykliczne oraz ich zastosowanie jako środków terapeutycznych - Google Patents

Związki spiroheterocykliczne oraz ich zastosowanie jako środków terapeutycznych

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Publication number
PL1888592T3
PL1888592T3 PL06740804T PL06740804T PL1888592T3 PL 1888592 T3 PL1888592 T3 PL 1888592T3 PL 06740804 T PL06740804 T PL 06740804T PL 06740804 T PL06740804 T PL 06740804T PL 1888592 T3 PL1888592 T3 PL 1888592T3
Authority
PL
Poland
Prior art keywords
therapeutic agents
spiroheterocyclic compounds
spiroheterocyclic
compounds
therapeutic
Prior art date
Application number
PL06740804T
Other languages
English (en)
Inventor
Mikhail Chafeev
Sultan Chowdhury
Robert Fraser
Jianmin Fu
Rajender Kamboj
Serguei Sviridov
Mehran Seid Bagherzadeh
Shifeng Liu
Jianyu Sun
Original Assignee
Xenon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenon Pharmaceuticals Inc filed Critical Xenon Pharmaceuticals Inc
Publication of PL1888592T3 publication Critical patent/PL1888592T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
PL06740804T 2005-04-11 2006-04-11 Związki spiroheterocykliczne oraz ich zastosowanie jako środków terapeutycznych PL1888592T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67096205P 2005-04-11 2005-04-11
EP06740804A EP1888592B1 (en) 2005-04-11 2006-04-11 Spiroheterocyclic compounds and their uses as therapeutic agents
PCT/US2006/013318 WO2006110654A1 (en) 2005-04-11 2006-04-11 Spiroheterocyclic compounds and their uses as therapeutic agents

Publications (1)

Publication Number Publication Date
PL1888592T3 true PL1888592T3 (pl) 2011-09-30

Family

ID=36694990

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06740804T PL1888592T3 (pl) 2005-04-11 2006-04-11 Związki spiroheterocykliczne oraz ich zastosowanie jako środków terapeutycznych

Country Status (27)

Country Link
US (2) US7799798B2 (pl)
EP (1) EP1888592B1 (pl)
JP (1) JP2008535916A (pl)
KR (1) KR20080007250A (pl)
CN (2) CN101967150A (pl)
AR (1) AR053710A1 (pl)
AT (1) ATE504587T1 (pl)
AU (1) AU2006235329B2 (pl)
BR (1) BRPI0608995A2 (pl)
CA (1) CA2604010A1 (pl)
DE (1) DE602006021169D1 (pl)
EC (1) ECSP077848A (pl)
ES (1) ES2362908T3 (pl)
HR (1) HRP20070499A2 (pl)
IL (1) IL186615A0 (pl)
MA (1) MA29685B1 (pl)
MX (1) MX2007012637A (pl)
MY (1) MY145694A (pl)
NO (1) NO20074620L (pl)
NZ (1) NZ561204A (pl)
PL (1) PL1888592T3 (pl)
RU (1) RU2428424C2 (pl)
SG (1) SG161264A1 (pl)
TN (1) TNSN07384A1 (pl)
TW (1) TW200720278A (pl)
WO (1) WO2006110654A1 (pl)
ZA (1) ZA200709004B (pl)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
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AR056968A1 (es) 2005-04-11 2007-11-07 Xenon Pharmaceuticals Inc Compuestos espiro-oxindol y composiciones farmacéuticas
AR053710A1 (es) 2005-04-11 2007-05-16 Xenon Pharmaceuticals Inc Compuestos espiroheterociclicos y sus usos como agentes terapeuticos
AR053713A1 (es) * 2005-04-20 2007-05-16 Xenon Pharmaceuticals Inc Compuestos heterociclicos y sus usos como agentes terapeuticos
WO2008046065A1 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Spiroheterocyclic compounds and their uses as therapeutic agents
TW200833695A (en) * 2006-10-12 2008-08-16 Xenon Pharmaceuticals Inc Use of spiro-oxindole compounds as therapeutic agents
WO2008046082A2 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Use of heterocyclic compounds as therapeutic agents
WO2008046087A2 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Spiro compounds and their uses as therapeutic agents
CL2007002953A1 (es) * 2006-10-12 2008-02-01 Xenon Pharmaceuticals Inc Compuestos derivados de espiro-oxindol; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento del dolor, cancer, prurito, hiperplasia prostatica benigna, hipercolesterolemia.
CN101522685A (zh) * 2006-10-12 2009-09-02 泽农医药公司 三环螺-吲哚酮衍生物及其作为治疗剂的用途
CN101641090B (zh) * 2006-12-19 2012-12-05 亚勒斯有限公司 莫达非尼在制备治疗多动腿综合征的药物中的应用
US7795228B2 (en) 2006-12-28 2010-09-14 Theracos, Inc. Spiroheterocyclic glycosides and methods of use
CA2685942A1 (en) * 2007-05-16 2008-11-27 Merck & Co., Inc. Spiroindalones
EP2209373B1 (en) * 2007-10-04 2012-05-23 Merck Sharp & Dohme Corp. N-substituted oxindoline derivatives as calcium channel blockers
EP2205079A4 (en) * 2007-10-04 2010-10-27 Merck Sharp & Dohme N-SUBSTITUTED OXINDOLINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS
UA101004C2 (en) 2007-12-13 2013-02-25 Теракос, Инк. Derivatives of benzylphenylcyclohexane and use thereof
KR101390081B1 (ko) 2008-04-29 2014-04-29 노파르티스 아게 기생충 질환의 치료를 위한 스피로－인돌 유도체
ME02702B (me) 2008-08-22 2017-10-20 Theracos Sub Llc Postupci za pripremu inhibitora sgl t2
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