CN101654483A - 产生嵌合异源多聚体的组合物和方法 - Google Patents

产生嵌合异源多聚体的组合物和方法 Download PDF

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Publication number
CN101654483A
CN101654483A CN200910149285A CN200910149285A CN101654483A CN 101654483 A CN101654483 A CN 101654483A CN 200910149285 A CN200910149285 A CN 200910149285A CN 200910149285 A CN200910149285 A CN 200910149285A CN 101654483 A CN101654483 A CN 101654483A
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sequence
polypeptide
chain
allos dimerization
bonding unit
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Chinese (zh)
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王材力
钟平宇
刘胜江
罗培志
李胜峰
王欣慰
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Abmaxis Inc
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Abmaxis Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN200910149285A 2001-08-01 2002-07-31 产生嵌合异源多聚体的组合物和方法 Pending CN101654483A (zh)

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US09/921,144 US6833441B2 (en) 2001-08-01 2001-08-01 Compositions and methods for generating chimeric heteromultimers
US09/921,144 2001-08-01

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CN101654483A true CN101654483A (zh) 2010-02-24

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CNA02818596XA Pending CN1558916A (zh) 2001-08-01 2002-07-31 产生嵌合异源多聚体的组合物和方法

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EP (1) EP1421117B1 (https=)
JP (2) JP2005506064A (https=)
CN (2) CN101654483A (https=)
CA (1) CA2455237C (https=)
MX (1) MXPA04001053A (https=)
WO (1) WO2003012069A2 (https=)

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CN108473554A (zh) * 2015-12-03 2018-08-31 Ucb生物制药私人有限公司 多特异性抗体
WO2024120199A1 (en) * 2022-12-08 2024-06-13 Analytical Biosciences Shanghai Limited Bispecific/multi-specific antibodies and uses thereof

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