CH622769A5 - - Google Patents
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- Publication number
- CH622769A5 CH622769A5 CH32679A CH32679A CH622769A5 CH 622769 A5 CH622769 A5 CH 622769A5 CH 32679 A CH32679 A CH 32679A CH 32679 A CH32679 A CH 32679A CH 622769 A5 CH622769 A5 CH 622769A5
- Authority
- CH
- Switzerland
- Prior art keywords
- formula
- compound
- spiro
- carbon atoms
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
- C07C49/675—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having three rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/62—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7203905A SE371190B (cs) | 1972-03-24 | 1972-03-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH622769A5 true CH622769A5 (cs) | 1981-04-30 |
Family
ID=20263107
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH428173A CH621110A5 (cs) | 1972-03-24 | 1973-03-23 | |
| CH32579A CH626044A5 (cs) | 1972-03-24 | 1979-01-12 | |
| CH32679A CH622769A5 (cs) | 1972-03-24 | 1979-01-12 | |
| CH32779A CH626045A5 (cs) | 1972-03-24 | 1979-01-12 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH428173A CH621110A5 (cs) | 1972-03-24 | 1973-03-23 | |
| CH32579A CH626044A5 (cs) | 1972-03-24 | 1979-01-12 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH32779A CH626045A5 (cs) | 1972-03-24 | 1979-01-12 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4172093A (cs) |
| JP (1) | JPS599540B2 (cs) |
| AT (1) | AT329045B (cs) |
| CA (1) | CA1032165A (cs) |
| CH (4) | CH621110A5 (cs) |
| DE (1) | DE2314636C2 (cs) |
| DK (1) | DK138598B (cs) |
| FI (1) | FI57253C (cs) |
| FR (1) | FR2177929B1 (cs) |
| GB (1) | GB1421208A (cs) |
| NO (1) | NO138628C (cs) |
| SE (1) | SE371190B (cs) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE47716B1 (en) * | 1977-08-05 | 1984-05-30 | Kabi Ab | Geminally disubstituted indene derivatives |
| CH641147A5 (de) * | 1979-01-17 | 1984-02-15 | Sandoz Ag | 3-amino-2-hydroxypropoxyaryl-derivat, seine herstellung und dieses enthaltende heilmittel. |
| CH647235A5 (de) * | 1980-02-13 | 1985-01-15 | Sandoz Ag | 4-(2,2-dialkylindan-1-yliden)piperidin derivate, ihre herstellung und verwendung. |
| IL103106A (en) * | 1991-09-25 | 1998-06-15 | Sanofi Elf | Sites of tynocyclopentanone oximes, their preparation and pharmaceutical preparations containing them |
| GB9309621D0 (en) * | 1993-05-11 | 1993-06-23 | Wellcome Found | Amide derivatives and their therapeutic use |
| US5877218A (en) * | 1994-01-10 | 1999-03-02 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
| MY113062A (en) * | 1994-05-10 | 2001-11-30 | The Wellcome Foundation Ltd | Amide derivatives and their therapeutic use |
| ES2241064T3 (es) | 1996-12-18 | 2005-10-16 | Teva Pharmaceutical Industries, Ltd. | Derivados de aminoindano. |
| US6124284A (en) * | 1998-07-16 | 2000-09-26 | Glaxo Wellcome Inc. | Bicyclic amide derivatives and their use as muscle relaxants |
| US6737547B1 (en) | 1998-12-31 | 2004-05-18 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using N-acyl-1H-aminoindenes |
| US20040010038A1 (en) * | 2002-02-27 | 2004-01-15 | Eran Blaugrund | Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors |
| GB0328906D0 (en) | 2003-12-12 | 2004-01-14 | Syngenta Participations Ag | Chemical compounds |
| US20070135518A1 (en) * | 2005-12-09 | 2007-06-14 | Marta Weinstock-Rosin | Use of low-dose ladostigil for neuroprotection |
| ES2632638T3 (es) * | 2005-12-09 | 2017-09-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Ladostigilo de baja dosis para el tratamiento de la deficiencia cognitiva |
| TW200744576A (en) * | 2006-02-24 | 2007-12-16 | Teva Pharma | Propargylated aminoindans, processes for preparation, and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1007323B (de) * | 1956-04-13 | 1957-05-02 | Schering Ag | Verfahren zur Herstellung von 1-Aminoindanen mit coronargefaesserweiternder Wirkung |
| US3308157A (en) * | 1964-08-07 | 1967-03-07 | Colgate Palmolive Co | N-(benzocyclobutene-1-loweralkyl)-carboxylic acid amides |
| US3360435A (en) * | 1964-09-15 | 1967-12-26 | Mead Johnson & Co | Treatment of depressed states |
| US3553093A (en) * | 1965-03-19 | 1971-01-05 | Xerox Corp | Color photoelectrophoretic imaging process |
| GB1139135A (en) * | 1965-10-01 | 1969-01-08 | Kefalas As | Aminoalkyl-substituted indanes and pharmaceutical compositions containing them |
| US3657440A (en) * | 1968-04-23 | 1972-04-18 | Ciba Geigy Corp | Aminoalkyl-spirocycloalkanes as analgetic agents |
| CH534120A (de) * | 1968-04-23 | 1973-02-28 | Ciba Geigy Ag | Verfahren zur Herstellung von neuen 1-Aminoalkyl-benzocycloalkan-2-spirocycloaliphatischen Verbindungen |
-
1972
- 1972-03-24 SE SE7203905A patent/SE371190B/xx unknown
-
1973
- 1973-03-16 FI FI817/73A patent/FI57253C/fi active
- 1973-03-20 CA CA166,508A patent/CA1032165A/en not_active Expired
- 1973-03-20 US US05/343,129 patent/US4172093A/en not_active Expired - Lifetime
- 1973-03-22 DK DK156173AA patent/DK138598B/da not_active IP Right Cessation
- 1973-03-22 AT AT255373A patent/AT329045B/de not_active IP Right Cessation
- 1973-03-23 FR FR7310580A patent/FR2177929B1/fr not_active Expired
- 1973-03-23 NO NO1209/73A patent/NO138628C/no unknown
- 1973-03-23 DE DE2314636A patent/DE2314636C2/de not_active Expired
- 1973-03-23 GB GB1422473A patent/GB1421208A/en not_active Expired
- 1973-03-23 JP JP48032772A patent/JPS599540B2/ja not_active Expired
- 1973-03-23 CH CH428173A patent/CH621110A5/de not_active IP Right Cessation
-
1979
- 1979-01-12 CH CH32579A patent/CH626044A5/de not_active IP Right Cessation
- 1979-01-12 CH CH32679A patent/CH622769A5/de not_active IP Right Cessation
- 1979-01-12 CH CH32779A patent/CH626045A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATA255373A (de) | 1975-07-15 |
| DE2314636C2 (de) | 1986-09-11 |
| CH626044A5 (cs) | 1981-10-30 |
| DK138598C (cs) | 1979-03-26 |
| CH621110A5 (cs) | 1981-01-15 |
| FI57253C (fi) | 1980-07-10 |
| AU5365173A (en) | 1974-09-26 |
| NO138628C (no) | 1978-10-11 |
| CH626045A5 (cs) | 1981-10-30 |
| CA1032165A (en) | 1978-05-30 |
| FR2177929B1 (cs) | 1976-10-22 |
| AT329045B (de) | 1976-04-26 |
| SE371190B (cs) | 1974-11-11 |
| FI57253B (fi) | 1980-03-31 |
| DE2314636A1 (de) | 1973-10-04 |
| FR2177929A1 (cs) | 1973-11-09 |
| US4172093A (en) | 1979-10-23 |
| NO138628B (no) | 1978-07-03 |
| JPS495957A (cs) | 1974-01-19 |
| DK138598B (da) | 1978-10-02 |
| GB1421208A (en) | 1976-01-14 |
| JPS599540B2 (ja) | 1984-03-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |