CA3081669A1 - Sample carrier for optical measurements - Google Patents

Sample carrier for optical measurements Download PDF

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Publication number
CA3081669A1
CA3081669A1 CA3081669A CA3081669A CA3081669A1 CA 3081669 A1 CA3081669 A1 CA 3081669A1 CA 3081669 A CA3081669 A CA 3081669A CA 3081669 A CA3081669 A CA 3081669A CA 3081669 A1 CA3081669 A1 CA 3081669A1
Authority
CA
Canada
Prior art keywords
sample carrier
sample
area
optical measurement
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3081669A
Other languages
English (en)
French (fr)
Inventor
Noam YORAV-RAPHAEL
Joseph Joel POLLAK
Sarah LEVY SCHREIER
Yochay Shlomo ESHEL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SD Sight Diagnostics Ltd
Original Assignee
SD Sight Diagnostics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SD Sight Diagnostics Ltd filed Critical SD Sight Diagnostics Ltd
Publication of CA3081669A1 publication Critical patent/CA3081669A1/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0321—One time use cells, e.g. integrally moulded
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6482—Sample cells, cuvettes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Measuring Cells (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CA3081669A 2017-11-14 2018-11-12 Sample carrier for optical measurements Pending CA3081669A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762585621P 2017-11-14 2017-11-14
US62/585,621 2017-11-14
PCT/IB2018/058861 WO2019097387A1 (en) 2017-11-14 2018-11-12 Sample carrier for optical measurements

Publications (1)

Publication Number Publication Date
CA3081669A1 true CA3081669A1 (en) 2019-05-23

Family

ID=64477225

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3081669A Pending CA3081669A1 (en) 2017-11-14 2018-11-12 Sample carrier for optical measurements

Country Status (7)

Country Link
US (5) US11921272B2 (enExample)
EP (1) EP3710810B1 (enExample)
JP (1) JP7214729B2 (enExample)
CN (1) CN111788471B (enExample)
AU (1) AU2018369859B2 (enExample)
CA (1) CA3081669A1 (enExample)
WO (1) WO2019097387A1 (enExample)

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US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
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EP3869257B1 (en) 2013-05-23 2024-05-08 S.D. Sight Diagnostics Ltd. Method and system for imaging a cell sample
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for preparing a monolayer of cells, particularly suitable for diagnosis
CN105659151B (zh) 2013-08-26 2018-06-29 思迪赛特诊断有限公司 数码显微系统与方法
CN107077732B (zh) 2014-08-27 2020-11-24 思迪赛特诊断有限公司 用于对数字显微镜计算聚焦变化的系统及方法
AU2016322966B2 (en) 2015-09-17 2021-10-14 S.D. Sight Diagnostics Ltd Methods and apparatus for detecting an entity in a bodily sample
US11733150B2 (en) 2016-03-30 2023-08-22 S.D. Sight Diagnostics Ltd. Distinguishing between blood sample components
EP3455626B1 (en) 2016-05-11 2025-08-06 S.D. Sight Diagnostics Ltd. Performing optical measurements on a sample
EP3455610B1 (en) 2016-05-11 2023-01-04 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
CA3081669A1 (en) 2017-11-14 2019-05-23 S.D. Sight Diagnostics Ltd Sample carrier for optical measurements
BR112022007708A2 (pt) 2019-10-22 2022-07-12 S D Sight Diagnostics Ltd Contabilização de erros em medições ópticas
CA3160695A1 (en) 2019-12-12 2021-06-17 S.D. Sight Diagnostics Ltd Analyzing an analyte disposed within a medium
CA3160697A1 (en) 2019-12-12 2021-06-17 S.D. Sight Diagnostics Ltd Classification models for analyzing a sample
BR112022011354A2 (pt) 2019-12-12 2022-08-23 S D Sight Diagnostics Ltd Geração artificial de uma imagem colorida de esfregaço sanguíneo
JP7744905B2 (ja) 2019-12-12 2025-09-26 エス．ディー．サイト ダイアグノスティックス リミテッド サンプルのオフフォーカス顕微鏡画像
EP4073508B1 (en) 2019-12-12 2025-02-05 S.D. Sight Diagnostics Ltd. Detecting platelets in a blood sample
WO2022009104A2 (en) 2020-07-07 2022-01-13 S.D. Sight Diagnostics Ltd Focusing a microscope using fluorescent images
US20250108367A1 (en) 2022-01-25 2025-04-03 S.D. Sight Diagnostics Ltd. Sample carrier for use with a bodily sample
GB202218615D0 (en) 2022-12-12 2023-01-25 S D Sight Diagnostics Ltd System and method for analyzing bodily samples
WO2024236537A1 (en) 2023-05-18 2024-11-21 S.D. Sight Diagnostics Ltd Apparatus and methods for microscopic analysis of a biological sample

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