DE69417900T2 - Vorrichtung und Verfahren zum schnellen und hochempfindlichen Erkennen und Zählen von Mikroorganismen mittels Fluoreszenz - Google Patents
Vorrichtung und Verfahren zum schnellen und hochempfindlichen Erkennen und Zählen von Mikroorganismen mittels FluoreszenzInfo
- Publication number
- DE69417900T2 DE69417900T2 DE69417900T DE69417900T DE69417900T2 DE 69417900 T2 DE69417900 T2 DE 69417900T2 DE 69417900 T DE69417900 T DE 69417900T DE 69417900 T DE69417900 T DE 69417900T DE 69417900 T2 DE69417900 T2 DE 69417900T2
- Authority
- DE
- Germany
- Prior art keywords
- microorganisms
- fluorescence
- counting
- fast
- highly sensitive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1468—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94402610A EP0713087B1 (de) | 1994-11-17 | 1994-11-17 | Vorrichtung und Verfahren zum schnellen und hochempfindlichen Erkennen und Zählen von Mikroorganismen mittels Fluoreszenz |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69417900D1 DE69417900D1 (de) | 1999-05-20 |
DE69417900T2 true DE69417900T2 (de) | 1999-11-11 |
Family
ID=8218061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69417900T Expired - Lifetime DE69417900T2 (de) | 1994-11-17 | 1994-11-17 | Vorrichtung und Verfahren zum schnellen und hochempfindlichen Erkennen und Zählen von Mikroorganismen mittels Fluoreszenz |
Country Status (4)
Country | Link |
---|---|
US (2) | US5663057A (de) |
EP (1) | EP0713087B1 (de) |
JP (1) | JP3035698B2 (de) |
DE (1) | DE69417900T2 (de) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6122396A (en) * | 1996-12-16 | 2000-09-19 | Bio-Tech Imaging, Inc. | Method of and apparatus for automating detection of microorganisms |
US6731100B1 (en) | 1997-05-05 | 2004-05-04 | Chemometec A/S | Method and a system for determination of somatic cells in milk |
EP0980516B1 (de) | 1997-05-05 | 2003-04-02 | ChemoMetec A/S | Bestimmung von partikeln in einer flüssigen probe |
US5796478A (en) * | 1997-07-25 | 1998-08-18 | Nalco Chemical Company | Monitoring of film forming living desposits |
US6221671B1 (en) * | 1997-12-12 | 2001-04-24 | Chemunex S.A. | Digital flow cytometer and method |
AU2884499A (en) * | 1998-03-02 | 1999-09-20 | Compucyte Corp. | Selective cell analysis |
US5972641A (en) * | 1998-08-28 | 1999-10-26 | Colifast Systems Asa | Rapid coliform detection system |
US6511819B2 (en) | 1998-08-28 | 2003-01-28 | Nye Colifast As | Rapid coliform detection system |
GB9903555D0 (en) * | 1999-02-16 | 1999-04-07 | The Technology Partnership Plc | Chemical and biological assay method and apparatus |
JP2000304689A (ja) * | 1999-04-21 | 2000-11-02 | Hiroyuki Ogawa | 投影観察方法、微生物検査方法および投影検出装置 |
WO2001046382A2 (en) * | 1999-12-21 | 2001-06-28 | Compucyte Corporation | Particle separation cassette and related methods |
EP1854873A3 (de) * | 2000-01-31 | 2008-03-19 | Matsushita Ecology Systems Co., Ltd. | Reagenziensatz zur Detektion von Mikroorganismen, Vorrichtung zur Quantifizierung von Mikroorganismen und Verfahren zur Quantifizierung von Mikroorganismen |
GB0004529D0 (en) * | 2000-02-25 | 2000-04-19 | The Technology Partnership Plc | Screening and diagnostics |
DE10100246A1 (de) * | 2001-01-05 | 2002-07-11 | Leica Microsystems | Mikroskop und Verfahren zum Betreiben eines Mikroskops |
US6750039B1 (en) | 2001-03-21 | 2004-06-15 | Boston Probes, Inc. | Filtration apparatus and method for the separation of microscopic entities from a fluid |
US6796710B2 (en) | 2001-06-08 | 2004-09-28 | Ethicon Endo-Surgery, Inc. | System and method of measuring and controlling temperature of optical fiber tip in a laser system |
US6775315B1 (en) * | 2001-06-08 | 2004-08-10 | Scott Allen Nield | Apparatus and method of directing a laser beam to a thermally managed beam dump in a laser system |
US6803208B2 (en) * | 2001-07-30 | 2004-10-12 | The United States Of America As Represented By The Secretary Of The Navy | Automated epifluorescence microscopy for detection of bacterial contamination in platelets |
US20030027219A1 (en) * | 2001-07-31 | 2003-02-06 | Ilsley Diane D. | Methods for depositing small volumes of protein fluids onto the surface of a substrate |
US7191103B2 (en) * | 2001-08-08 | 2007-03-13 | Hewlett-Packard Development Company, L.P. | Predominant color identification in digital images |
ATE437216T1 (de) * | 2001-09-06 | 2009-08-15 | Genomic Profiling Systems Inc | Schnellnachweis replizierender zellen |
US20030138906A1 (en) * | 2001-11-05 | 2003-07-24 | Ingun Tryland | Fluorescence test for measuring heterotrophic bacteria in water |
US20030186252A1 (en) * | 2002-04-01 | 2003-10-02 | Ilsley Diane D. | Array based hybridization assays employing enzymatically generated labeled target nucleic acids and compositions for practicing the same |
DE10347123B4 (de) * | 2003-10-02 | 2005-07-28 | Petra Dr.-Ing. Perner | Verfahren zur automatischen Bestimmung auf einem Träger gesammelter luftgetragener Partikel insbesondere Pilzsporen |
US7217937B2 (en) * | 2003-11-21 | 2007-05-15 | Brightwell Technologies | Automatic identification of suspended particles |
DE102005006237A1 (de) * | 2005-02-10 | 2006-08-24 | Henkel Kgaa | Verfahren zur Bestimmung von Keimen |
US20070037135A1 (en) * | 2005-08-08 | 2007-02-15 | Barnes Russell H | System and method for the identification and quantification of a biological sample suspended in a liquid |
US9057046B2 (en) * | 2005-09-26 | 2015-06-16 | Rapid Micro Biosystems, Inc. | Cassette containing growth medium |
WO2008130655A1 (en) | 2007-04-20 | 2008-10-30 | The General Hospital Corporation | Methods for counting cells |
US20080305514A1 (en) * | 2007-06-06 | 2008-12-11 | Alcon Research, Ltd. | Method for detecting microbes |
EP2197350A2 (de) * | 2007-09-11 | 2010-06-23 | Baxter International Inc. | Infusionstherapie-sensorsystem |
GB2476663A (en) * | 2009-12-31 | 2011-07-06 | Blood Analysis Ltd | Detection of microorganisms |
CN102224260B (zh) | 2008-09-24 | 2015-11-25 | 施特劳斯控股公司 | 用于检测分析物的试剂盒和装置 |
US8481302B2 (en) * | 2008-11-03 | 2013-07-09 | General Electric Company | Total bacteria monitoring system |
US20100112630A1 (en) * | 2008-11-03 | 2010-05-06 | Scott Martell Boyette | Methods for measuring microbiological content in aqueous media |
JP5451770B2 (ja) * | 2008-11-24 | 2014-03-26 | コーニンクレッカ フィリップス エヌ ヴェ | 流体サンプルの迅速なフィルタ解析方法及び装置 |
EP2194368B1 (de) | 2008-12-03 | 2019-07-17 | Grundfos Management A/S | Sensorsystem zum Erfassen und Spezifizieren von einzelnen Partikeln in einem Fluid |
WO2010077304A2 (en) | 2008-12-16 | 2010-07-08 | Biomerieux, Inc. | Methods for the characterization of microorganisms on solid or semi-solid media |
WO2010080643A1 (en) * | 2008-12-18 | 2010-07-15 | Biovigilant Systems, Inc. | Integrated microbial collector |
EP2241875A1 (de) * | 2009-04-14 | 2010-10-20 | Koninklijke Philips Electronics N.V. | UP-Konzentration von organischen Mikroobjekten für die mikroskopische Abbildung |
US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
DE102011076238A1 (de) | 2011-05-20 | 2012-11-22 | Siemens Ag | Anordnung und Verfahren zur optischen Analyse und spezifischen Isolierung von biologischen Proben |
DE102011076221B3 (de) * | 2011-05-20 | 2012-07-12 | Siemens Aktiengesellschaft | Automatisierter CTC Nachweis |
HUE049333T2 (hu) | 2011-11-07 | 2020-09-28 | Rapid Micro Biosystems Inc | Kazetta sterilitási vizsgálathoz |
CN104169719B (zh) | 2011-12-29 | 2017-03-08 | 思迪赛特诊断有限公司 | 用于检测生物样品中病原体的方法和系统 |
EP4060016A1 (de) | 2012-04-16 | 2022-09-21 | Rapid Micro Biosystems, Inc. | Zellkultivierungsvorrichtung |
US8993259B2 (en) | 2012-05-02 | 2015-03-31 | Charles River Laboratories, Inc. | Method of viability staining with membrane permeable fluorescent dye and membrane impermeable fluorescence quencher |
WO2013166338A2 (en) * | 2012-05-02 | 2013-11-07 | Charles River Laboratories, Inc. | Cell capture system and use thereof |
CN104755931B (zh) * | 2012-05-02 | 2016-08-31 | 查尔斯河实验室公司 | 用于检测细胞样品中的活细胞的方法 |
IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for obtaining a monolayer of cells, for use specifically for diagnosis |
CN105874052B (zh) | 2013-11-04 | 2019-05-21 | 查尔斯河实验室公司 | 过滤系统和其使用 |
AU2016322966B2 (en) | 2015-09-17 | 2021-10-14 | S.D. Sight Diagnostics Ltd | Methods and apparatus for detecting an entity in a bodily sample |
CA3018536A1 (en) | 2016-03-30 | 2017-10-05 | S.D. Sight Diagnostics Ltd | Distinguishing between blood sample components |
US11307196B2 (en) | 2016-05-11 | 2022-04-19 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
AU2017263807B2 (en) | 2016-05-11 | 2023-02-02 | S.D. Sight Diagnostics Ltd | Performing optical measurements on a sample |
EP3679154A4 (de) * | 2017-09-07 | 2021-05-26 | Eagle Analytical Services, Inc. | Verfahren und system zur durchflusszytometrie-fluoreszenzdetektion von reaktiven materialien in viskosen nicht filtrierbaren materialien |
EP3710810B1 (de) | 2017-11-14 | 2023-09-06 | S.D. Sight Diagnostics Ltd. | Probenträger für optische messungen |
FR3086951B1 (fr) | 2018-10-05 | 2021-02-26 | Redberry | Methode et dispositif pour la detection d'au moins un microorganisme selon sa cinetique de marquage, et support de detection |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4180831A (en) * | 1975-05-23 | 1979-12-25 | Bausch & Lomb Incorporated | Image analysis data extraction |
US4647531A (en) * | 1984-02-06 | 1987-03-03 | Ortho Diagnostic Systems, Inc. | Generalized cytometry instrument and methods of use |
US5246829A (en) * | 1984-10-04 | 1993-09-21 | Immunotech | Products for separation applicable to cells in the immunopurification field |
US4745285A (en) * | 1986-08-21 | 1988-05-17 | Becton Dickinson And Company | Multi-color fluorescence analysis with single wavelength excitation |
US4845653A (en) * | 1987-05-07 | 1989-07-04 | Becton, Dickinson And Company | Method of displaying multi-parameter data sets to aid in the analysis of data characteristics |
US4845552A (en) * | 1987-08-20 | 1989-07-04 | Bruno Jaggi | Quantitative light microscope using a solid state detector in the primary image plane |
US5093866A (en) * | 1990-02-09 | 1992-03-03 | Hamilton Equine Associates Limited | Fluorescence and motility characterization system for cells, bacteria, and particles in fluids |
US5103101A (en) * | 1991-03-04 | 1992-04-07 | Etec Systems, Inc. | Multiphase printing for E-beam lithography |
JP3102938B2 (ja) * | 1991-12-30 | 2000-10-23 | シスメックス株式会社 | 粒子画像分析装置 |
-
1994
- 1994-11-17 EP EP94402610A patent/EP0713087B1/de not_active Expired - Lifetime
- 1994-11-17 DE DE69417900T patent/DE69417900T2/de not_active Expired - Lifetime
-
1995
- 1995-06-21 US US08/493,130 patent/US5663057A/en not_active Expired - Lifetime
- 1995-11-17 JP JP7323740A patent/JP3035698B2/ja not_active Expired - Lifetime
-
1997
- 1997-06-06 US US08/870,294 patent/US5891394A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0713087B1 (de) | 1999-04-14 |
US5663057A (en) | 1997-09-02 |
DE69417900D1 (de) | 1999-05-20 |
US5891394A (en) | 1999-04-06 |
JPH08292145A (ja) | 1996-11-05 |
EP0713087A1 (de) | 1996-05-22 |
JP3035698B2 (ja) | 2000-04-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |