CA2803056C - Fused pyrimidine derivatives for inhibition of tyrosine kinase activity - Google Patents
Fused pyrimidine derivatives for inhibition of tyrosine kinase activity Download PDFInfo
- Publication number
- CA2803056C CA2803056C CA2803056A CA2803056A CA2803056C CA 2803056 C CA2803056 C CA 2803056C CA 2803056 A CA2803056 A CA 2803056A CA 2803056 A CA2803056 A CA 2803056A CA 2803056 C CA2803056 C CA 2803056C
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- Prior art keywords
- phenyl
- thieno
- pyrimidin
- acrylamide
- yloxy
- Prior art date
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- C07—ORGANIC CHEMISTRY
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- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20100059686 | 2010-06-23 | ||
| KR10-2010-0059686 | 2010-06-23 | ||
| PCT/KR2011/004482 WO2011162515A2 (en) | 2010-06-23 | 2011-06-20 | Novel fused pyrimidine derivatives for inhd3ition of tyrosine kinase activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2803056A1 CA2803056A1 (en) | 2011-12-29 |
| CA2803056C true CA2803056C (en) | 2017-05-16 |
Family
ID=45371929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2803056A Active CA2803056C (en) | 2010-06-23 | 2011-06-20 | Fused pyrimidine derivatives for inhibition of tyrosine kinase activity |
Country Status (31)
| Country | Link |
|---|---|
| US (4) | USRE46511E1 (https=) |
| EP (2) | EP2585470B1 (https=) |
| JP (2) | JP5834347B2 (https=) |
| KR (2) | KR101587506B1 (https=) |
| CN (2) | CN105061438B (https=) |
| AR (2) | AR081978A1 (https=) |
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