CA2085037A1 - Compositions pharmaceutiques stabilisees contenant un compose inhibiteur de la hmg-coa reductase - Google Patents

Compositions pharmaceutiques stabilisees contenant un compose inhibiteur de la hmg-coa reductase

Info

Publication number
CA2085037A1
CA2085037A1 CA2085037A CA2085037A CA2085037A1 CA 2085037 A1 CA2085037 A1 CA 2085037A1 CA 2085037 A CA2085037 A CA 2085037A CA 2085037 A CA2085037 A CA 2085037A CA 2085037 A1 CA2085037 A1 CA 2085037A1
Authority
CA
Canada
Prior art keywords
hmg
coa reductase
reductase inhibitor
inhibitor compound
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2085037A
Other languages
English (en)
Other versions
CA2085037C (fr
Inventor
Mohan B. Kabadi
Richard Victor Vivilecchia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36808687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2085037(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2085037A1 publication Critical patent/CA2085037A1/fr
Application granted granted Critical
Publication of CA2085037C publication Critical patent/CA2085037C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002085037A 1991-12-12 1992-12-10 Compositions pharmaceutiques stabilisees contenant un compose inhibiteur de la hmg-coa reductase Expired - Lifetime CA2085037C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80566791A 1991-12-12 1991-12-12
US805,667 1991-12-12
CN93100650A CN1041794C (zh) 1991-12-12 1993-01-30 含有一种β－羟基－β－甲基戊二酸单酰辅酶A还原酶抑制剂的稳定的药物组合物

Publications (2)

Publication Number Publication Date
CA2085037A1 true CA2085037A1 (fr) 1993-06-13
CA2085037C CA2085037C (fr) 2000-11-28

Family

ID=36808687

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002085037A Expired - Lifetime CA2085037C (fr) 1991-12-12 1992-12-10 Compositions pharmaceutiques stabilisees contenant un compose inhibiteur de la hmg-coa reductase

Country Status (31)

Country Link
US (1) US5356896A (fr)
EP (1) EP0547000B1 (fr)
JP (1) JP2774037B2 (fr)
KR (1) KR100253824B1 (fr)
CN (1) CN1041794C (fr)
AT (1) AT401870B (fr)
AU (1) AU661075B2 (fr)
CA (1) CA2085037C (fr)
CH (1) CH684309A5 (fr)
CY (1) CY1994A (fr)
CZ (1) CZ287776B6 (fr)
DE (1) DE4240430B4 (fr)
DK (1) DK0547000T3 (fr)
ES (1) ES2142819T3 (fr)
FI (1) FI114284B (fr)
FR (1) FR2684876B1 (fr)
GB (1) GB2262229B (fr)
GR (1) GR3032929T3 (fr)
HK (1) HK25597A (fr)
HU (2) HU9203780D0 (fr)
IL (1) IL104041A (fr)
IT (1) IT1256698B (fr)
LU (1) LU88201A1 (fr)
MX (1) MX9207152A (fr)
NO (1) NO302099B1 (fr)
NZ (1) NZ245421A (fr)
PT (1) PT547000E (fr)
RO (1) RO111542B1 (fr)
RU (1) RU2121835C1 (fr)
SK (1) SK281710B6 (fr)
ZA (1) ZA929642B (fr)

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* Cited by examiner, † Cited by third party
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