NO973814D0 - Basisk stabilisert sammensetning av HMG-CoA-reduktase inhibitor - Google Patents

Basisk stabilisert sammensetning av HMG-CoA-reduktase inhibitor

Info

Publication number
NO973814D0
NO973814D0 NO973814A NO973814A NO973814D0 NO 973814 D0 NO973814 D0 NO 973814D0 NO 973814 A NO973814 A NO 973814A NO 973814 A NO973814 A NO 973814A NO 973814 D0 NO973814 D0 NO 973814D0
Authority
NO
Norway
Prior art keywords
hmg
coa reductase
reductase inhibitor
stabilized composition
basic stabilized
Prior art date
Application number
NO973814A
Other languages
English (en)
Other versions
NO973814L (no
NO316724B1 (no
Inventor
Toyojiro Muramatsu
Katsumi Mashita
Yasuo Shinoda
Hironori Sassa
Hiroyuki Kawashima
Yoshio Tanizawa
Hideatsu Takeuchi
Original Assignee
Kowa Co
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co, Nissan Chemical Ind Ltd filed Critical Kowa Co
Publication of NO973814D0 publication Critical patent/NO973814D0/no
Publication of NO973814L publication Critical patent/NO973814L/no
Publication of NO316724B1 publication Critical patent/NO316724B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
NO19973814A 1995-12-22 1997-08-19 Basisk stabilisert sammensetning av HMG-CoA-reduktase inhibitor NO316724B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP35465495 1995-12-22
PCT/JP1996/003722 WO1997023200A1 (en) 1995-12-22 1996-12-20 Pharmaceutical composition stabilized with a basic agent

Publications (3)

Publication Number Publication Date
NO973814D0 true NO973814D0 (no) 1997-08-19
NO973814L NO973814L (no) 1997-10-13
NO316724B1 NO316724B1 (no) 2004-04-19

Family

ID=18439011

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19973814A NO316724B1 (no) 1995-12-22 1997-08-19 Basisk stabilisert sammensetning av HMG-CoA-reduktase inhibitor
NO2011006C NO2011006I2 (no) 1995-12-22 2011-05-04 Pitavastatin, valgfritt i form av av farmasøytisk akseptabelt salt eller ester

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO2011006C NO2011006I2 (no) 1995-12-22 2011-05-04 Pitavastatin, valgfritt i form av av farmasøytisk akseptabelt salt eller ester

Country Status (26)

Country Link
EP (1) EP0814782B1 (no)
JP (1) JP3276962B2 (no)
KR (1) KR100348842B1 (no)
CN (1) CN1137684C (no)
AT (1) ATE228354T1 (no)
AU (1) AU725622B2 (no)
CA (1) CA2213608C (no)
CZ (1) CZ288545B6 (no)
DE (2) DE69625046T2 (no)
DK (1) DK0814782T3 (no)
ES (1) ES2183023T3 (no)
FR (1) FR11C0007I2 (no)
HU (1) HU227798B1 (no)
IL (1) IL121565A (no)
MX (1) MX9706389A (no)
NO (2) NO316724B1 (no)
NZ (1) NZ324446A (no)
PL (1) PL186907B1 (no)
PT (1) PT814782E (no)
RU (1) RU2142790C1 (no)
SI (1) SI0814782T1 (no)
SK (1) SK282991B6 (no)
TW (1) TW436294B (no)
UA (1) UA29513C2 (no)
WO (1) WO1997023200A1 (no)
ZA (1) ZA9610792B (no)

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SI20109A (sl) * 1998-12-16 2000-06-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Stabilna farmacevtska formulacija
US6569461B1 (en) 1999-03-08 2003-05-27 Merck & Co., Inc. Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors
EP1161236A1 (en) * 1999-03-08 2001-12-12 Merck & Co., Inc. Dihydroxy open-acid and salts of hmg-co-a reductase inhibitors
EP1036563A1 (en) * 1999-03-08 2000-09-20 MERCK & CO. INC. Delayed-release oral formulation of dihydroxy open acid simvastatin and salts and esters thereof
JP4048780B2 (ja) 1999-12-13 2008-02-20 株式会社豊田中央研究所 キノリン誘導体化合物及び有機電界発光素子
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USRE44578E1 (en) 2000-04-10 2013-11-05 Teva Pharmaceutical Industries, Ltd. Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
US6242003B1 (en) 2000-04-13 2001-06-05 Novartis Ag Organic compounds
SK16982002A3 (sk) 2000-06-09 2003-04-01 Lek Pharmaceuticals D. D. Stabilizovaná farmaceuticky účinná kompozícia a liečivý prípravok túto kompozíciu obsahujúci
US6806290B2 (en) 2000-06-09 2004-10-19 Lek Pharmaceuticals D.D. Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same
US20060127474A1 (en) 2001-04-11 2006-06-15 Oskar Kalb Pharmaceutical compositions comprising fluvastatin
TW200404544A (en) * 2002-06-17 2004-04-01 Kowa Co Controlled release pharmaceutical composition
WO2004026297A1 (ja) * 2002-09-20 2004-04-01 Kowa Co., Ltd. 外用剤
AR041089A1 (es) 2003-05-15 2005-05-04 Merck & Co Inc Procedimiento y composiciones farmaceutiicas para tratar aterosclerosis, dislipidemias y afecciones relacionadas
AU2004308332B2 (en) 2003-12-23 2008-04-10 Merck Sharp & Dohme Corp. Anti-hypercholesterolemic compounds
WO2005063294A1 (ja) 2003-12-30 2005-07-14 Kowa Company, Ltd. γ-セクレターゼ複合体形成阻害剤
SE0400235D0 (sv) 2004-02-06 2004-02-06 Active Biotech Ab New composition containing quinoline compounds
US8314124B2 (en) 2004-02-06 2012-11-20 Active Biotech Ab Crystalline salts of quinoline compounds and methods for preparing them
JP4728226B2 (ja) 2004-02-25 2011-07-20 興和株式会社 Ｃｄｃ４２タンパク質の核内移行促進剤及びそのスクリーニング方法
WO2005079846A1 (ja) 2004-02-25 2005-09-01 Kowa Company, Ltd. Racタンパク質の核内移行促進剤及びそのスクリーニング方法
US20060211752A1 (en) 2004-03-16 2006-09-21 Kohn Leonard D Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
AU2006204038A1 (en) 2005-01-06 2006-07-13 Merck & Co., Inc. Drug combination therapy and pharmaceutical compositions for treating inflammatory disorders
EP1726962A1 (en) * 2005-05-24 2006-11-29 Leiden University Medical Center Apolipoprotein E plasma levels for monitoring and reducing the risk of cardiovascular disease
CN101103983B (zh) * 2006-07-14 2012-09-26 海南盛科生命科学研究院 一种用碱试剂稳定的含匹伐他汀钙的药用组合物及制备工艺
WO2008156721A1 (en) 2007-06-20 2008-12-24 Merck & Co., Inc. Diphenyl substituted alkanes
US8372877B2 (en) 2010-04-16 2013-02-12 Cumberland Pharmaceuticals Stabilized statin formulations
JPWO2012046772A1 (ja) 2010-10-06 2014-02-24 国立大学法人 東京大学 リンパ浮腫予防治療剤
RU2598842C2 (ru) 2011-01-20 2016-09-27 Мерк Шарп Энд Домэ Корп. Антагонисты рецептора минералокортикоидов
US9399064B2 (en) 2011-04-12 2016-07-26 Sawai Pharmaceutical Co., Ltd. Pitavastatin-containing preparation and method for producing same
WO2012139495A1 (en) 2011-04-13 2012-10-18 Merck Sharp & Dohme Corp. Mineralocorticoid receptor antagonists
WO2012153181A1 (en) 2011-05-11 2012-11-15 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Pharmaceutical composition comprising pitavastatin or its pharmaceutically acceptable salts
CN102861018A (zh) * 2011-07-05 2013-01-09 南京长澳医药科技有限公司 一种匹伐他汀钙制剂及其制备工艺
JP5809467B2 (ja) * 2011-07-12 2015-11-11 エルメッド エーザイ株式会社 ピタバスタチン含有組成物及びその製造方法
JP5844574B2 (ja) * 2011-08-10 2016-01-20 共和薬品工業株式会社 ピタバスタチンを含有する安定化された薬物組成物
WO2013055606A1 (en) 2011-10-13 2013-04-18 Merck Sharp & Dohme Corp. Mineralocorticoid receptor antagonists
JP5190159B1 (ja) 2012-08-08 2013-04-24 興和株式会社 医薬
CN102885797A (zh) * 2012-10-29 2013-01-23 福州海王福药制药有限公司 一种含匹伐他汀钙的组合物及其制备方法和应用
WO2015066490A1 (en) 2013-10-31 2015-05-07 Ohio University Prevention and treatment of non-alcoholic fatty liver disease
KR20160147007A (ko) 2014-05-30 2016-12-21 화이자 인코포레이티드 선택적인 안드로겐 수용체 조절제로서의 카보니트릴 유도체
US10023567B2 (en) 2014-07-18 2018-07-17 Ohio University Imidazole and thiazole compositions for modifying biological signaling
CN105343008A (zh) * 2015-12-15 2016-02-24 青岛华之草医药科技有限公司 一种匹伐他汀钙组合物
CN107913257A (zh) * 2016-10-10 2018-04-17 北京阜康仁生物制药科技有限公司 一种包含瑞舒伐他汀钙的药物组合物及其制备方法
JP6937195B2 (ja) * 2017-09-01 2021-09-22 興和株式会社 医薬組成物
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HU9203780D0 (en) * 1991-12-12 1993-03-29 Sandoz Ag Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them

Also Published As

Publication number Publication date
AU725622B2 (en) 2000-10-19
NZ324446A (en) 1999-08-30
PT814782E (pt) 2003-04-30
EP0814782A1 (en) 1998-01-07
CA2213608C (en) 2003-07-08
HUP9903536A2 (hu) 2000-03-28
HUP9903536A3 (en) 2001-06-28
TW436294B (en) 2001-05-28
MX9706389A (es) 1998-08-30
NO973814L (no) 1997-10-13
ZA9610792B (en) 1997-07-09
SK116097A3 (en) 1998-03-04
PL186907B1 (pl) 2004-03-31
DK0814782T3 (da) 2002-12-16
ES2183023T3 (es) 2003-03-16
CN1137684C (zh) 2004-02-11
WO1997023200A1 (en) 1997-07-03
NO2011006I1 (no) 2011-06-06
DE69625046T2 (de) 2003-04-10
AU1171597A (en) 1997-07-17
NO316724B1 (no) 2004-04-19
SK282991B6 (sk) 2003-01-09
SI0814782T1 (en) 2003-04-30
DE69625046D1 (de) 2003-01-09
FR11C0007I1 (no) 2011-04-22
CA2213608A1 (en) 1997-07-03
IL121565A (en) 2002-02-10
CZ288545B6 (cs) 2001-07-11
IL121565A0 (en) 1998-02-08
JP3276962B2 (ja) 2002-04-22
HU227798B1 (en) 2012-03-28
EP0814782B1 (en) 2002-11-27
RU2142790C1 (ru) 1999-12-20
KR100348842B1 (ko) 2002-12-31
JPH11503763A (ja) 1999-03-30
UA29513C2 (uk) 2000-11-15
DE122011000014I1 (de) 2011-11-03
FR11C0007I2 (fr) 2012-03-16
CZ268197A3 (cs) 1998-05-13
ATE228354T1 (de) 2002-12-15
PL321868A1 (en) 1997-12-22
KR19980702370A (ko) 1998-07-15
CN1189098A (zh) 1998-07-29
NO2011006I2 (no) 2012-10-01

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