IS6654A - Stöðugt gabapentín með pH innan stýrðra marka - Google Patents
Stöðugt gabapentín með pH innan stýrðra markaInfo
- Publication number
- IS6654A IS6654A IS6654A IS6654A IS6654A IS 6654 A IS6654 A IS 6654A IS 6654 A IS6654 A IS 6654A IS 6654 A IS6654 A IS 6654A IS 6654 A IS6654 A IS 6654A
- Authority
- IS
- Iceland
- Prior art keywords
- controlled range
- gabapentin
- stable gabapentin
- stable
- controlled
- Prior art date
Links
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title abstract 6
- 229960002870 gabapentin Drugs 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/44—Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Anesthesiology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21196600P | 2000-06-16 | 2000-06-16 | |
| PCT/US2001/019427 WO2001097782A1 (en) | 2000-06-16 | 2001-06-15 | Stable gabapentin having ph within a controlled range |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS6654A true IS6654A (is) | 2002-12-11 |
Family
ID=22788986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS6654A IS6654A (is) | 2000-06-16 | 2002-12-11 | Stöðugt gabapentín með pH innan stýrðra marka |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US20020045662A1 (is) |
| EP (1) | EP1294364A4 (is) |
| JP (1) | JP2003535885A (is) |
| KR (2) | KR20060123782A (is) |
| CN (1) | CN1447684A (is) |
| AU (2) | AU2001266992B8 (is) |
| CA (1) | CA2411787C (is) |
| CZ (1) | CZ200339A3 (is) |
| HR (1) | HRP20030002A2 (is) |
| HU (1) | HUP0301919A3 (is) |
| IL (1) | IL153441A0 (is) |
| IS (1) | IS6654A (is) |
| NZ (1) | NZ523546A (is) |
| PL (1) | PL363155A1 (is) |
| SK (1) | SK302003A3 (is) |
| WO (1) | WO2001097782A1 (is) |
| YU (1) | YU95302A (is) |
| ZA (1) | ZA200210144B (is) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7056951B2 (en) * | 2000-09-26 | 2006-06-06 | Mutual Pharmaceutical Co., Inc. | Stable solid dosage forms of amino acids and processes for producing same |
| US7612112B2 (en) | 2001-10-25 | 2009-11-03 | Depomed, Inc. | Methods of treatment using a gastric retained gabapentin dosage |
| TWI312285B (en) | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
| US20030119908A1 (en) * | 2001-12-21 | 2003-06-26 | Zambon Group S.P.A. | Stable gabapentin compositions |
| CA2478471A1 (en) * | 2002-04-16 | 2003-10-30 | Taro Pharmaceutical Industries Ltd. | Process for preparing gabapentin |
| WO2004058168A2 (en) * | 2002-12-20 | 2004-07-15 | Dynogen Pharmaceuticals, Inc. | METHODS OF TREATING NON-PAINFUL BLADDER DISORDERS USING α2δ SUBUNIT CALCIUM CHANNEL MODULATORS |
| DK1492519T3 (da) * | 2003-03-21 | 2007-03-05 | Dynogen Pharmaceuticals Inc | Fremgangsmåder til behandling af lidelser i den nedre urinvej ved anvendelse af alfa-2-delta-underenhedscalciumkanalsmodulatorer med glat muskel-modulatorer |
| WO2005046566A2 (en) * | 2003-08-04 | 2005-05-26 | Sun Pharmaceutical Industries Limited | Stable gabapentin containing composition |
| US20050187295A1 (en) * | 2004-02-19 | 2005-08-25 | Surendra Kalyan | Processes for the preparation of gabapentin |
| WO2005117526A2 (en) * | 2004-06-03 | 2005-12-15 | Matrix Laboratories Ltd | An improved process for the purification of gabapentin |
| US8367105B2 (en) | 2004-11-10 | 2013-02-05 | Teva Pharmaceutical Industries, Ltd. | Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby |
| WO2006052254A2 (en) * | 2004-11-10 | 2006-05-18 | Teva Pharmaceutical Industries Ltd. | Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby |
| US20090176882A1 (en) | 2008-12-09 | 2009-07-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
| US20080103334A1 (en) * | 2006-10-26 | 2008-05-01 | Ipca Laboratories Ltd | Process For Synthesis Of Gabapentin |
| EP2007710A1 (en) * | 2007-02-28 | 2008-12-31 | Teva Pharmaceutical Industries Ltd. | Preparation of gabapentin by liquid-liquid extraction |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
| DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE2611690A1 (de) * | 1976-03-19 | 1977-09-22 | Goedecke Ag | Cyclische sulfonyloxyimide |
| US4960931A (en) * | 1988-05-02 | 1990-10-02 | Warner-Lambert Company | Gabapentin mohohydrate and a process for producing the same |
| US4894476A (en) * | 1988-05-02 | 1990-01-16 | Warner-Lambert Company | Gabapentin monohydrate and a process for producing the same |
| DE3928183A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Lactamfreie cyclische aminosaeuren |
| DE3928182A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von gabapentin |
| US5319135A (en) * | 1989-08-25 | 1994-06-07 | Warner-Lambert Company | Process for cyclic amino acid anticonvulsant compounds |
| DE3928184A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte |
| US5132451A (en) * | 1989-08-25 | 1992-07-21 | Warner-Lambert Company | Process for cyclic amino acid anticonvulsant compounds |
| PH27359A (en) * | 1989-08-25 | 1993-06-21 | Warner Lambert Co | Process for cyclic amino acid anticonvulsant compounds |
| US5136091A (en) * | 1989-11-16 | 1992-08-04 | Lonza Ltd. | Process for the production of 1-(aminomethyl) cyclohexane acetic acid |
| US5149870A (en) * | 1989-11-16 | 1992-09-22 | Lonza Ltd. | Process for the production of 1-(aminomethyl)cyclohexane acetic acid |
| FI905584L (fi) * | 1989-11-16 | 1991-05-17 | Lonza Ag | Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra. |
| US5084479A (en) * | 1990-01-02 | 1992-01-28 | Warner-Lambert Company | Novel methods for treating neurodegenerative diseases |
| US5510381A (en) * | 1995-05-15 | 1996-04-23 | Warner-Lambert Company | Method of treatment of mania and bipolar disorder |
| IL119890A (en) * | 1996-12-24 | 2002-03-10 | Teva Pharma | Gabapentin form iii and preparation of gabapentin form ii |
| WO1999018063A2 (en) * | 1997-10-07 | 1999-04-15 | Warner-Lambert Company | Process for preparing a cyclic amino acid anticonvulsant compound |
| CU23051A3 (es) * | 1998-05-15 | 2005-06-24 | Warner Lambert Co | Composiciones solidas que contienen derivados de acido gamma-aminobutirico y procesos para prepararlas. |
| US7309719B1 (en) * | 1998-05-15 | 2007-12-18 | Warner Lambert Company, Llc | Stabilized pharmaceutical preparation of gamma-aminobutyric acid derivatives and process for preparing the same |
| FR2781793B1 (fr) * | 1998-08-03 | 2001-07-20 | Prographarm Lab | Procede de fabrication de granules de gabapentine enrobes |
| HU225502B1 (en) * | 1998-12-29 | 2007-01-29 | Richter Gedeon Vegyeszet | Process for producing 1-(amino-metyl)-cyclohexene-acetic-acid and intermediates |
| ES2164527B1 (es) * | 1999-04-26 | 2003-04-01 | Medichen S A | Procedimiento de obtencion de gabapentina de calidad farmaceutica. |
| US6294198B1 (en) * | 1999-08-24 | 2001-09-25 | Purepac Pharmaceutical Co. | Pharmaceutical tablet formulation containing gabapentin with improved physical and chemical characteristics and method of making the same |
| AU2001268426A1 (en) * | 2000-06-16 | 2002-01-02 | Teva Pharmaceutical Industries Ltd. | Stable gabapentin containing more than 2o ppm of chlorine ion |
-
2001
- 2001-06-15 YU YU95302A patent/YU95302A/sh unknown
- 2001-06-15 IL IL15344101A patent/IL153441A0/xx unknown
- 2001-06-15 AU AU2001266992A patent/AU2001266992B8/en not_active Ceased
- 2001-06-15 CZ CZ200339A patent/CZ200339A3/cs unknown
- 2001-06-15 WO PCT/US2001/019427 patent/WO2001097782A1/en not_active Application Discontinuation
- 2001-06-15 CA CA002411787A patent/CA2411787C/en not_active Expired - Fee Related
- 2001-06-15 EP EP01944600A patent/EP1294364A4/en not_active Withdrawn
- 2001-06-15 NZ NZ523546A patent/NZ523546A/en unknown
- 2001-06-15 JP JP2002503259A patent/JP2003535885A/ja active Pending
- 2001-06-15 AU AU6699201A patent/AU6699201A/xx active Pending
- 2001-06-15 US US09/880,922 patent/US20020045662A1/en not_active Abandoned
- 2001-06-15 CN CN01814117A patent/CN1447684A/zh active Pending
- 2001-06-15 PL PL01363155A patent/PL363155A1/xx unknown
- 2001-06-15 SK SK30-2003A patent/SK302003A3/sk unknown
- 2001-06-15 KR KR1020067020064A patent/KR20060123782A/ko not_active Ceased
- 2001-06-15 KR KR1020027016981A patent/KR100667721B1/ko not_active Expired - Fee Related
- 2001-06-15 HR HR20030002A patent/HRP20030002A2/xx not_active Application Discontinuation
- 2001-06-15 HU HU0301919A patent/HUP0301919A3/hu unknown
-
2002
- 2002-08-26 US US10/227,244 patent/US20030055109A1/en not_active Abandoned
- 2002-12-11 IS IS6654A patent/IS6654A/is unknown
- 2002-12-13 ZA ZA200210144A patent/ZA200210144B/en unknown
-
2004
- 2004-01-16 US US10/759,573 patent/US20040147607A1/en not_active Abandoned
-
2006
- 2006-01-20 US US11/336,552 patent/US20060122271A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1294364A1 (en) | 2003-03-26 |
| KR100667721B1 (ko) | 2007-01-15 |
| CZ200339A3 (cs) | 2003-06-18 |
| US20030055109A1 (en) | 2003-03-20 |
| HUP0301919A2 (hu) | 2003-09-29 |
| JP2003535885A (ja) | 2003-12-02 |
| CN1447684A (zh) | 2003-10-08 |
| ZA200210144B (en) | 2004-10-08 |
| US20020045662A1 (en) | 2002-04-18 |
| US20040147607A1 (en) | 2004-07-29 |
| US20060122271A1 (en) | 2006-06-08 |
| EP1294364A4 (en) | 2004-06-16 |
| IL153441A0 (en) | 2003-07-06 |
| SK302003A3 (en) | 2003-07-01 |
| WO2001097782A1 (en) | 2001-12-27 |
| AU6699201A (en) | 2002-01-02 |
| KR20030010700A (ko) | 2003-02-05 |
| HUP0301919A3 (en) | 2006-01-30 |
| KR20060123782A (ko) | 2006-12-04 |
| PL363155A1 (en) | 2004-11-15 |
| AU2001266992B2 (en) | 2005-08-04 |
| YU95302A (sh) | 2006-05-25 |
| CA2411787C (en) | 2007-03-20 |
| CA2411787A1 (en) | 2001-12-27 |
| NZ523546A (en) | 2005-04-29 |
| AU2001266992B8 (en) | 2005-12-01 |
| HRP20030002A2 (en) | 2005-10-31 |
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