BRPI0924997A2 - Método para preparar um composto de éster do ácido aril-2-tetrazoil etil carbâmico. - Google Patents

Método para preparar um composto de éster do ácido aril-2-tetrazoil etil carbâmico.

Info

Publication number
BRPI0924997A2
BRPI0924997A2 BRPI0924997-4A BRPI0924997A BRPI0924997A2 BR PI0924997 A2 BRPI0924997 A2 BR PI0924997A2 BR PI0924997 A BRPI0924997 A BR PI0924997A BR PI0924997 A2 BRPI0924997 A2 BR PI0924997A2
Authority
BR
Brazil
Prior art keywords
tetrazoyl
aryl
preparing
acid ester
carbamic acid
Prior art date
Application number
BRPI0924997-4A
Other languages
English (en)
Inventor
Nahm Ryune Cho
Ju Young Lee
Se Il Lee
Hyun Seok Lee
Dong Ho Lee
Hui Ho Kim
Dae Won Lee
Moo Yong Uhm
Sang Chul Lim
Original Assignee
Sk Biopharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sk Biopharmaceuticals Co Ltd filed Critical Sk Biopharmaceuticals Co Ltd
Publication of BRPI0924997A2 publication Critical patent/BRPI0924997A2/pt
Publication of BRPI0924997B1 publication Critical patent/BRPI0924997B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • C07D257/06Five-membered rings with nitrogen atoms directly attached to the ring carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • C12P17/12Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0924997-4A 2009-06-22 2009-10-14 Método para preparar um composto de éster do ácido 1-aril-2- tetrazoil etil carbâmico BRPI0924997B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20090055576 2009-06-22
KR10-2009-0055576 2009-06-22
PCT/KR2009/005906 WO2010150946A1 (en) 2009-06-22 2009-10-14 Method for preparation of carbamic acid (r)-1-aryl-2-tetrazolyl-ethyl ester

Publications (2)

Publication Number Publication Date
BRPI0924997A2 true BRPI0924997A2 (pt) 2015-08-11
BRPI0924997B1 BRPI0924997B1 (pt) 2024-01-16

Family

ID=43354688

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0924997-4A BRPI0924997B1 (pt) 2009-06-22 2009-10-14 Método para preparar um composto de éster do ácido 1-aril-2- tetrazoil etil carbâmico

Country Status (17)

Country Link
US (1) US8501436B2 (pt)
EP (1) EP2445890B1 (pt)
JP (1) JP5683580B2 (pt)
KR (1) KR101708433B1 (pt)
CN (1) CN102803233B (pt)
AU (1) AU2009348523B2 (pt)
BR (1) BRPI0924997B1 (pt)
CA (1) CA2765566C (pt)
CL (1) CL2011003244A1 (pt)
ES (1) ES2541590T3 (pt)
IL (1) IL216786A (pt)
MX (1) MX2011013982A (pt)
MY (1) MY155662A (pt)
PL (1) PL2445890T3 (pt)
RU (1) RU2508290C2 (pt)
WO (1) WO2010150946A1 (pt)
ZA (1) ZA201109362B (pt)

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KR102421013B1 (ko) * 2016-05-19 2022-07-14 에스케이바이오팜 주식회사 삼차신경통을 예방 또는 치료하기 위한 카바메이트 화합물의 용도
KR102489052B1 (ko) * 2016-05-19 2023-01-16 에스케이바이오팜 주식회사 섬유근육통 또는 섬유근육통의 연관된 기능적 증후군을 예방 또는 치료하기 위한 카바메이트 화합물의 용도
WO2018111000A1 (ko) 2016-12-14 2018-06-21 에스케이바이오팜 주식회사 카바메이트 화합물을 포함하는 비경구용 액상 제제
KR102635938B1 (ko) 2016-12-14 2024-02-13 에스케이바이오팜 주식회사 양극성 장애의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
US11033531B2 (en) 2016-12-14 2021-06-15 Sk Biopharmaceuticals Co., Ltd. Use of carbamate compound for preventing, alleviating, or treating tremors or tremor syndrome
KR102635931B1 (ko) 2016-12-14 2024-02-13 에스케이바이오팜 주식회사 가려움증의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
KR102635936B1 (ko) 2016-12-14 2024-02-13 에스케이바이오팜 주식회사 탈수초성 질환의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
US20210085646A1 (en) 2016-12-14 2021-03-25 Sk Biopharmaceuticals Co., Ltd. Orally Disintegrated Tablet Comprising Carbamate Compound
KR20200074157A (ko) 2017-11-14 2020-06-24 에스케이바이오팜 주식회사 카바메이트 화합물을 포함하는 조현병의 예방, 경감 또는 치료용 배합물
KR20200074155A (ko) 2017-11-14 2020-06-24 에스케이바이오팜 주식회사 근긴장증의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
US20200268711A1 (en) 2017-11-14 2020-08-27 Sk Biopharmaceuticals Co., Ltd. Use Of Carbamate Compound For Reducing Or Treating Developmental Disorders Including Fragile X Syndrome, Angelman Syndrome Or Rett Syndrome
EP3711760B1 (en) 2017-11-14 2024-02-14 SK Biopharmaceuticals Co., Ltd. Use of carbamate compound for preventing or treating diseases associated with increase in late sodium current
KR20200074156A (ko) 2017-11-14 2020-06-24 에스케이바이오팜 주식회사 내장통 또는 내장 질환에서 기인한 통증을 예방, 경감 또는 치료하기 위한 카바메이트 화합물의 용도
DK3711758T3 (da) 2017-11-14 2024-04-08 Sk Biopharmaceuticals Co Ltd Anvendelse af en carbamatforbindelse til forebyggelse, lindring eller behandling af fraværsanfald eller epilepsi med fraværsanfald
EP3854392A4 (en) 2018-09-21 2022-08-17 SK Biopharmaceuticals Co., Ltd. USE OF A CARBAMATE COMPOUND FOR THE PREVENTION, ATTENUATION OR TREATMENT OF CONCOMITANT EPILEPTIC SEIZURES
CN113015524A (zh) * 2018-09-21 2021-06-22 爱思开生物制药株式会社 氨基甲酸酯化合物和包含其的制剂在预防、缓解或治疗急性应激障碍或创伤后应激障碍中的用途
WO2020080866A1 (ko) 2018-10-19 2020-04-23 에스케이바이오팜 주식회사 카바메이트 화합물의 당뇨병성 말초 신경병증 또는 화학요법 유발 말초 신경병증의 예방, 완화 또는 치료를 위한 용도
CA3154266A1 (en) * 2019-10-24 2021-04-29 Sk Biopharmaceuticals Co., Ltd. Method for preparing aryl 2-tetrazol-2-yl ketone with improved selectivity
US10611737B1 (en) * 2019-10-24 2020-04-07 Sk Biopharmaceuticals Co., Ltd. Method for preparing aryl 2-tetrazol-2-yl ketone with improved selectivity
JP2023503088A (ja) 2019-11-22 2023-01-26 エスケー バイオファーマスティカルズ カンパニー リミテッド カルバメート化合物を含む経口用医薬組成物及びその製造方法
CN110982757B (zh) * 2019-12-30 2021-04-06 浙江工业大学 阴沟肠杆菌zjph1903及应用
WO2022031099A1 (ko) 2020-08-06 2022-02-10 에스케이바이오팜 주식회사 카바메이트 화합물을 포함하는 경구용 고형 제제 및 이의 제조방법
CN111778198B (zh) * 2020-08-18 2021-12-10 杭州医学院 一种藤黄细球菌hmc01及其在不对称还原制备手性醇中的应用
WO2023152711A1 (en) * 2022-02-12 2023-08-17 Metrochem Api Pvt Ltd Process for the preparation of cenobamate and intermediates thereof
ES2931000B2 (es) * 2022-07-14 2023-07-07 Univ Madrid Complutense Proceso para la preparación de cenobamato

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RU2012102051A (ru) 2013-07-27
CN102803233B (zh) 2017-03-01
ES2541590T3 (es) 2015-07-22
CA2765566A1 (en) 2010-12-29
BRPI0924997B1 (pt) 2024-01-16
KR101708433B1 (ko) 2017-02-22
IL216786A (en) 2014-09-30
MX2011013982A (es) 2013-01-29
US20100323410A1 (en) 2010-12-23
ZA201109362B (en) 2012-08-29
IL216786A0 (en) 2012-02-29
JP2012530513A (ja) 2012-12-06
CA2765566C (en) 2016-04-12
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CN102803233A (zh) 2012-11-28
EP2445890A1 (en) 2012-05-02
MY155662A (en) 2015-11-13
US8501436B2 (en) 2013-08-06
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AU2009348523B2 (en) 2015-02-26
EP2445890B1 (en) 2015-05-06
WO2010150946A1 (en) 2010-12-29
JP5683580B2 (ja) 2015-03-11
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AU2009348523A1 (en) 2012-01-12
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