MX2011013982A - Metodo para la preparacion de este ( r ) - 1 - aril - 2 - tetrazolil - etilico de acido carbomico. - Google Patents

Metodo para la preparacion de este ( r ) - 1 - aril - 2 - tetrazolil - etilico de acido carbomico.

Info

Publication number
MX2011013982A
MX2011013982A MX2011013982A MX2011013982A MX2011013982A MX 2011013982 A MX2011013982 A MX 2011013982A MX 2011013982 A MX2011013982 A MX 2011013982A MX 2011013982 A MX2011013982 A MX 2011013982A MX 2011013982 A MX2011013982 A MX 2011013982A
Authority
MX
Mexico
Prior art keywords
tetrazolyl
aryl
preparation
carbamic acid
thyl ester
Prior art date
Application number
MX2011013982A
Other languages
English (en)
Inventor
Sang Chul Lim
Moo Yong Uhm
Nahm Ryune Cho
Dae Won Lee
Ju Young Lee
Hui Ho Kim
Dong Ho Lee
Hyun Seok Lee
Se Ll Lee
Original Assignee
Sk Biopharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sk Biopharmaceuticals Co Ltd filed Critical Sk Biopharmaceuticals Co Ltd
Publication of MX2011013982A publication Critical patent/MX2011013982A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C07D257/06—Five-membered rings with nitrogen atoms directly attached to the ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se divulga un método para la preparación de éster (R)-1-aril-2-tetrazolil-etílico de ácido carbámico, que comprende la reducción asimétrica de arilcetona y la carbamatación de alcohol.
MX2011013982A 2009-06-22 2009-10-14 Metodo para la preparacion de este ( r ) - 1 - aril - 2 - tetrazolil - etilico de acido carbomico. MX2011013982A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20090055576 2009-06-22
PCT/KR2009/005906 WO2010150946A1 (en) 2009-06-22 2009-10-14 Method for preparation of carbamic acid (r)-1-aryl-2-tetrazolyl-ethyl ester

Publications (1)

Publication Number Publication Date
MX2011013982A true MX2011013982A (es) 2013-01-29

Family

ID=43354688

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011013982A MX2011013982A (es) 2009-06-22 2009-10-14 Metodo para la preparacion de este ( r ) - 1 - aril - 2 - tetrazolil - etilico de acido carbomico.

Country Status (17)

Country Link
US (1) US8501436B2 (es)
EP (1) EP2445890B1 (es)
JP (1) JP5683580B2 (es)
KR (1) KR101708433B1 (es)
CN (1) CN102803233B (es)
AU (1) AU2009348523B2 (es)
BR (1) BRPI0924997B1 (es)
CA (1) CA2765566C (es)
CL (1) CL2011003244A1 (es)
ES (1) ES2541590T3 (es)
IL (1) IL216786A (es)
MX (1) MX2011013982A (es)
MY (1) MY155662A (es)
PL (1) PL2445890T3 (es)
RU (1) RU2508290C2 (es)
WO (1) WO2010150946A1 (es)
ZA (1) ZA201109362B (es)

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KR102421013B1 (ko) * 2016-05-19 2022-07-14 에스케이바이오팜 주식회사 삼차신경통을 예방 또는 치료하기 위한 카바메이트 화합물의 용도
KR102421006B1 (ko) * 2016-05-19 2022-07-14 에스케이바이오팜 주식회사 두통의 예방학적 치료를 위한 카바메이트 화합물의 용도
KR102635931B1 (ko) 2016-12-14 2024-02-13 에스케이바이오팜 주식회사 가려움증의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
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US11033531B2 (en) 2016-12-14 2021-06-15 Sk Biopharmaceuticals Co., Ltd. Use of carbamate compound for preventing, alleviating, or treating tremors or tremor syndrome
CA3081226A1 (en) 2017-11-14 2019-05-23 Sk Biopharmaceuticals Co., Ltd. Blend containing carbamate compound for prevention, mitigation, or treatment of schizophrenia
WO2019098628A1 (ko) 2017-11-14 2019-05-23 에스케이바이오팜 주식회사 결신 발작 또는 결신 발작을 나타내는 뇌전증의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
US11406620B2 (en) 2017-11-14 2022-08-09 Sk Biopharmaceuticals Co., Ltd. Use of carbamate compound for preventing or treating diseases associated with increase in late sodium current
KR20200074155A (ko) 2017-11-14 2020-06-24 에스케이바이오팜 주식회사 근긴장증의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
KR20200074156A (ko) 2017-11-14 2020-06-24 에스케이바이오팜 주식회사 내장통 또는 내장 질환에서 기인한 통증을 예방, 경감 또는 치료하기 위한 카바메이트 화합물의 용도
EP3711761A4 (en) 2017-11-14 2021-11-24 SK Biopharmaceuticals Co., Ltd. USE OF A CARBAMATE COMPOUND FOR ALLEVATION OR TREATMENT OF DEVELOPMENTAL DISORDERS INCLUDING FRAGILE X SYNDROME, ANGELMAN SYNDROME OR RETT SYNDROME
JP7417595B2 (ja) 2018-09-21 2024-01-18 エスケー バイオファーマスティカルズ カンパニー リミテッド てんかん重積状態の予防、軽減又は治療のためのカルバメート化合物の使用
WO2020060251A1 (ko) 2018-09-21 2020-03-26 에스케이바이오팜 주식회사 카바메이트 화합물 및 이를 포함하는 배합물의 급성 스트레스 장애 또는 외상 후 스트레스 장애의 예방, 경감 또는 치료를 위한 용도
AU2019361856A1 (en) 2018-10-19 2021-05-06 Sk Biopharmaceuticals Co., Ltd. Use of carbamate compound for preventing, alleviating or treating diabetic peripheral neuropathy or chemotherapy-induced peripheral neuropathy
US10611737B1 (en) * 2019-10-24 2020-04-07 Sk Biopharmaceuticals Co., Ltd. Method for preparing aryl 2-tetrazol-2-yl ketone with improved selectivity
CN114901647B (zh) * 2019-10-24 2024-04-02 爱思开生物制药株式会社 具有改进的选择性的制备芳基2-四唑-2-基酮的方法
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CN110982757B (zh) * 2019-12-30 2021-04-06 浙江工业大学 阴沟肠杆菌zjph1903及应用
WO2022031099A1 (ko) 2020-08-06 2022-02-10 에스케이바이오팜 주식회사 카바메이트 화합물을 포함하는 경구용 고형 제제 및 이의 제조방법
CN111778198B (zh) * 2020-08-18 2021-12-10 杭州医学院 一种藤黄细球菌hmc01及其在不对称还原制备手性醇中的应用
WO2023152711A1 (en) * 2022-02-12 2023-08-17 Metrochem Api Pvt Ltd Process for the preparation of cenobamate and intermediates thereof
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IL216786A0 (en) 2012-02-29
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US8501436B2 (en) 2013-08-06
CN102803233B (zh) 2017-03-01
MY155662A (en) 2015-11-13
RU2012102051A (ru) 2013-07-27
KR20100137389A (ko) 2010-12-30
AU2009348523B2 (en) 2015-02-26
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EP2445890A1 (en) 2012-05-02
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CN102803233A (zh) 2012-11-28
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