BRPI0114704B8 - composto de imidazol fundido a arila ou heteroarila, suas composições farmacêuticas, bem como seu uso - Google Patents

composto de imidazol fundido a arila ou heteroarila, suas composições farmacêuticas, bem como seu uso

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Publication number
BRPI0114704B8
BRPI0114704B8 BRPI0114704A BR0114704A BRPI0114704B8 BR PI0114704 B8 BRPI0114704 B8 BR PI0114704B8 BR PI0114704 A BRPI0114704 A BR PI0114704A BR 0114704 A BR0114704 A BR 0114704A BR PI0114704 B8 BRPI0114704 B8 BR PI0114704B8
Authority
BR
Brazil
Prior art keywords
alkyl
optionally containing
heteroatoms selected
aryl
well
Prior art date
Application number
BRPI0114704A
Other languages
English (en)
Portuguese (pt)
Other versions
BR0114704A (pt
BRPI0114704B1 (pt
Inventor
Kawai Akiyoshi
Taniguchi Kana
Shinjyo Katsuhiro
Nakao Kazunari
Matsumizu Miyako
Uneo Naomi
Nukui Seiji
Kato Tomoki
Miyake Yoriko
Hashizume Yoshinobu
Okumura Yoshiyuki
Original Assignee
Askat Inc
Pfizer
Raqualia Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Askat Inc, Pfizer, Raqualia Pharma Inc filed Critical Askat Inc
Publication of BR0114704A publication Critical patent/BR0114704A/pt
Publication of BRPI0114704B1 publication Critical patent/BRPI0114704B1/pt
Publication of BRPI0114704B8 publication Critical patent/BRPI0114704B8/pt

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    • C07—ORGANIC CHEMISTRY
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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