BR9805897A - M-todos de isolamento de materiais alvo biolÄgicos que utilizam part¡culas magne-ticas de s¡lica - Google Patents

M-todos de isolamento de materiais alvo biolÄgicos que utilizam part¡culas magne-ticas de s¡lica

Info

Publication number
BR9805897A
BR9805897A BR9805897A BR9805897A BR9805897A BR 9805897 A BR9805897 A BR 9805897A BR 9805897 A BR9805897 A BR 9805897A BR 9805897 A BR9805897 A BR 9805897A BR 9805897 A BR9805897 A BR 9805897A
Authority
BR
Brazil
Prior art keywords
silica particles
target materials
biological target
use magnetic
isolation methods
Prior art date
Application number
BR9805897A
Other languages
English (en)
Inventor
Criag E Smith
Charles K York
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25134438&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9805897(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Promega Corp filed Critical Promega Corp
Priority claimed from PCT/US1998/001194 external-priority patent/WO1998036298A1/en
Publication of BR9805897A publication Critical patent/BR9805897A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/832—Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
    • Y10S977/838—Magnetic property of nanomaterial
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y10S977/916—Gene therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/92—Detection of biochemical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/932—Specified use of nanostructure for electronic or optoelectronic application
    • Y10S977/953—Detector using nanostructure
    • Y10S977/96—Of magnetic property

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Compounds Of Iron (AREA)
  • Silicon Compounds (AREA)
  • Saccharide Compounds (AREA)
BR9805897A 1997-01-21 1998-01-21 M-todos de isolamento de materiais alvo biolÄgicos que utilizam part¡culas magne-ticas de s¡lica BR9805897A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/785,097 US6027945A (en) 1997-01-21 1997-01-21 Methods of isolating biological target materials using silica magnetic particles
PCT/US1998/001194 WO1998036298A1 (en) 1997-02-12 1998-01-21 Azobenzene-containing polymer films

Publications (1)

Publication Number Publication Date
BR9805897A true BR9805897A (pt) 1999-08-24

Family

ID=25134438

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9805897A BR9805897A (pt) 1997-01-21 1998-01-21 M-todos de isolamento de materiais alvo biolÄgicos que utilizam part¡culas magne-ticas de s¡lica

Country Status (9)

Country Link
US (5) US6027945A (pt)
EP (2) EP0895546B1 (pt)
JP (1) JP3253638B2 (pt)
AU (1) AU732756B2 (pt)
BR (1) BR9805897A (pt)
CA (1) CA2249393A1 (pt)
DE (3) DE69841555D1 (pt)
DK (1) DK1367137T3 (pt)
WO (1) WO1998031840A1 (pt)

Families Citing this family (261)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
DE19520398B4 (de) * 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
KR100463475B1 (ko) 1995-06-08 2005-06-22 로셰 디아그노스틱스 게엠베하 자기성피그먼트
JP2965131B2 (ja) * 1995-07-07 1999-10-18 東洋紡績株式会社 核酸結合用磁性担体およびそれを用いる核酸単離方法
JP4034351B2 (ja) 1996-04-25 2008-01-16 バイオアレイ ソリューションズ エルエルシー 粒子近接表面の光制御した動電学的アッセンブリ
ATE229371T1 (de) 1997-01-21 2002-12-15 Grace W R & Co Siliciumdioxidadsorbent auf magnetischem träger
US20050287583A1 (en) * 1997-01-21 2005-12-29 Promega Corporation Methods and kits for isolating biological target materials using silica magnetic particles
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
WO1998050567A1 (en) * 1997-05-02 1998-11-12 Abbott Laboratories Reagents and methods useful for detecting diseases of the prostate
DE19743518A1 (de) * 1997-10-01 1999-04-15 Roche Diagnostics Gmbh Automatisierbare universell anwendbare Probenvorbereitungsmethode
US20080064108A1 (en) * 1997-12-10 2008-03-13 Tony Baker Urine Preservation System
US7569342B2 (en) * 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
EP0937497B9 (en) 1997-12-25 2003-10-29 Tosoh Corporation Magnetic carrier, preparation thereof, and method of extraction of nucleic acid
US7078224B1 (en) * 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
WO1999058664A1 (en) 1998-05-14 1999-11-18 Whitehead Institute For Biomedical Research Solid phase technique for selectively isolating nucleic acids
EP0969090A1 (en) * 1998-05-27 2000-01-05 QIAGEN GmbH Rapid and simple process for isolation of circular nucleic acids
US6368866B1 (en) 1998-08-03 2002-04-09 Reference Diagnostics, Inc. Rapid separation assay for total iron binding capacity
US6703228B1 (en) * 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
US6361947B1 (en) 1998-10-27 2002-03-26 Affymetrix, Inc. Complexity management and analysis of genomic DNA
US5973138A (en) * 1998-10-30 1999-10-26 Becton Dickinson And Company Method for purification and manipulation of nucleic acids using paramagnetic particles
AU762188B2 (en) * 1998-11-30 2003-06-19 Inm Institut Fur Neue Materialien Gmbh Magnetic particles for purifying nucleic acids
EP1162444A4 (en) * 1999-01-18 2007-02-21 Prec System Science Co Ltd CONCENTRATION DEVICE USING MAGNETIC PARTICLES AND METHOD THEREOF
FI990082A0 (fi) * 1999-01-18 1999-01-18 Labsystems Oy Puhdistusprosessi magneettipartikkeleita käyttäen
WO2000043199A1 (en) * 1999-01-20 2000-07-27 Reference Diagnostics, Inc. Magnetically responsive gel particle
US6270970B1 (en) * 1999-05-14 2001-08-07 Promega Corporation Mixed-bed solid phase and its use in the isolation of nucleic acids
AU778486B2 (en) * 1999-05-14 2004-12-09 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
EP1621618B1 (en) 1999-05-14 2011-10-26 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
US6310199B1 (en) 1999-05-14 2001-10-30 Promega Corporation pH dependent ion exchange matrix and method of use in the isolation of nucleic acids
DK1069131T3 (da) * 1999-07-15 2006-06-26 Qiagen Gmbh Fremgangsmåde til at skille partikelformige substrater fra en oplösning med et minimalt tab af partikler
DE19937607A1 (de) * 1999-08-09 2001-02-15 Bilatec Ges Zur Entwicklung Bi Reagenzienkit zur Isolierung von Nukleinsäuren
EP1510578A3 (en) * 1999-08-20 2005-03-16 Promega Corporation Simultaneous isolation and quantitation of dna
WO2001014590A2 (en) * 1999-08-20 2001-03-01 Promega Corporation Simultaneous isolation and quantitation of dna
US6503761B1 (en) * 1999-10-19 2003-01-07 Kimberly-Clark Worldwide, Inc. Selective removal of contaminants from a surface using articles having magnets
US6841393B2 (en) 1999-10-19 2005-01-11 Kimberly-Clark Worldwide, Inc. Selective removal of contaminants from a surface using colored particles and articles having magnets
US6958225B2 (en) 1999-10-27 2005-10-25 Affymetrix, Inc. Complexity management of genomic DNA
CZ20021608A3 (cs) * 1999-11-17 2003-06-18 Roche Diagnostics Gmbh Magnetické skleněné částice, metody jejich přípravy a použití
US6936414B2 (en) * 1999-12-22 2005-08-30 Abbott Laboratories Nucleic acid isolation method and kit
CA2400724C (en) * 2000-03-24 2009-11-24 Qiagen Gmbh Porous ferro- or ferrimagnetic glass particles for isolating molecules
ATE419919T1 (de) * 2000-05-19 2009-01-15 Becton Dickinson Co System und verfahren zur behandlung von magnetpartikeln in test-flüssigkeiten zum sammeln von dna und rna
US6672458B2 (en) * 2000-05-19 2004-01-06 Becton, Dickinson And Company System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample
GB0013658D0 (en) * 2000-06-05 2000-07-26 Dynal Asa Nucleic acid isolation
WO2001098765A1 (en) * 2000-06-21 2001-12-27 Bioarray Solutions, Ltd. Multianalyte molecular analysis
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
WO2002000342A2 (en) * 2000-06-23 2002-01-03 Irm, Llc Method and apparatus for performing an assay
ATE469246T1 (de) * 2000-09-06 2010-06-15 Transnetyx Inc Computer-basiertes verfahren und system zum screenen von genomischer dns
US20050272085A1 (en) * 2000-09-06 2005-12-08 Hodge Timothy A Methods for forensic and congenic screening
WO2002020842A1 (en) * 2000-09-06 2002-03-14 Transnetyx, Inc. System, method and apparatus for transgenic and targeted mutagenesis screening
EP1978110B1 (en) * 2000-09-06 2010-05-26 Transnetyx, Inc. Computer-based method and system for screening genomic DNA
US20050266494A1 (en) * 2000-09-06 2005-12-01 Hodge Timothy A System and method for computer network ordering of biological testing
US20050239125A1 (en) * 2000-09-06 2005-10-27 Hodge Timothy A Methods for genotype screening
US7494817B2 (en) * 2000-09-06 2009-02-24 Transnet Yx, Inc. Methods for genotype screening using magnetic particles
US20030082605A1 (en) * 2000-09-06 2003-05-01 Hodge Timothy A. Genomic DNA detection method and system thereof
US20030087286A1 (en) * 2000-09-06 2003-05-08 Hodge Timothy A. Isolation of eukaryotic genomic DNA using magnetically responsive solid functionalized particles
US20030207289A1 (en) * 2001-09-04 2003-11-06 Hodge Timothy A. Detection of genetic sequences using a bipartite probe
CA2428532C (en) * 2000-11-13 2009-05-19 Promega Corporation Lysate clearance and nucleic acid isolation using silanized silica matrices
US6607667B2 (en) * 2000-11-28 2003-08-19 W. R. Grace & Co.-Conn. Method for adsorbing substances using silica adsorbent on magnetic substrate
EP1339876A2 (en) * 2000-11-28 2003-09-03 Promega Corporation Purification of dna sequencing reactions using silica magnetic particles
US6794141B2 (en) * 2000-12-22 2004-09-21 Arcturus Bioscience, Inc. Nucleic acid amplification
JP4065405B2 (ja) * 2001-01-19 2008-03-26 デー エル エム ドクトル ミュラー アクチェンゲゼルシャフト プラスミドｄｎａを含有する細胞溶解物を製造するためのバイオマスの処理法
US6855499B1 (en) 2001-02-16 2005-02-15 Cortex Biochem, Inc. Magnetic isolation and purification of nucleic acids
EP2090655B1 (en) 2001-02-16 2013-05-08 Promega Corporation Magnetic isolation and purification of nucleic acids
US20030022203A1 (en) * 2001-04-23 2003-01-30 Rajan Kumar Cellular Arrays
US6656587B2 (en) 2001-05-02 2003-12-02 Phillips Plastics Corporation Composite particles
US6849186B2 (en) * 2001-05-02 2005-02-01 Phillips Plastic Corporation Composite particles
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US7217513B2 (en) * 2001-07-10 2007-05-15 Massachusetts Institute Of Technology Apparatus and method for isolating a nucleic acid from a sample
US7285412B2 (en) * 2001-07-27 2007-10-23 Surface Logix Inc. Device for magnetic immobilization of cells
US7169577B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US7169578B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US20030040129A1 (en) * 2001-08-20 2003-02-27 Shah Haresh P. Binding assays using magnetically immobilized arrays
US20060014186A1 (en) * 2001-09-04 2006-01-19 Hodge Timothy A Methods for genotype screening of a strain disposed on an adsorbent carrier
US20040137449A1 (en) * 2001-10-05 2004-07-15 Nargessi R D Magnetic isolation and purification of nucleic acids
ES2661167T3 (es) 2001-10-15 2018-03-27 Bioarray Solutions Ltd. Análisis multiplexado de loci polimórficos mediante consulta simultánea y detección mediada por enzimas
EP1442045B1 (en) 2001-11-06 2009-01-07 Cortex Biochem Inc. Isolation and purification of nucleic acids
JP2005538929A (ja) 2002-01-16 2005-12-22 ダイナル バイオテック エイエスエイ 単一サンプルからの核酸及びタンパク質の単離方法
WO2003068788A1 (en) * 2002-02-13 2003-08-21 Medimolecular Pty. Ltd. Method of isolating nucleic acids from stool samples
US20060246434A1 (en) * 2002-03-15 2006-11-02 Erlander Mark G Nucleic acid amplification
US7214427B2 (en) * 2002-03-21 2007-05-08 Aviva Biosciences Corporation Composite beads comprising magnetizable substance and electro-conductive substance
GB0207975D0 (en) * 2002-04-05 2002-05-15 Genovision As Isolating nucleic acid
GB0210766D0 (en) * 2002-05-10 2002-06-19 Genovision As Isolating nucleic acid
EP1376129B1 (en) * 2002-06-27 2007-10-10 Toyo Boseki Kabushiki Kaisha Magnetic carrier for biological substance, production method thereof and isolation method of biological substance using the same
GB0215185D0 (en) 2002-07-01 2002-08-07 Genovision As Binding a target substance
US20040126783A1 (en) * 2002-07-10 2004-07-01 Massachusetts Institute Of Technology Apparatus and method for isolating a nucleic acid from a sample
WO2004013633A2 (en) * 2002-07-29 2004-02-12 Axxima Pharmaceuticals Ag Method for isolating atp binding proteins by means of immobolized protein inhibitors
US7183104B1 (en) 2002-08-23 2007-02-27 Duane Morris Llp Separator and particle detection system
US7176036B2 (en) * 2002-09-20 2007-02-13 Arrowhead Center, Inc. Electroactive microspheres and methods
US7526114B2 (en) 2002-11-15 2009-04-28 Bioarray Solutions Ltd. Analysis, secure access to, and transmission of array images
GB0229287D0 (en) * 2002-12-16 2003-01-22 Dna Res Innovations Ltd Polyfunctional reagents
US7601491B2 (en) * 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
US20040157219A1 (en) * 2003-02-06 2004-08-12 Jianrong Lou Chemical treatment of biological samples for nucleic acid extraction and kits therefor
JP2004000922A (ja) * 2003-03-26 2004-01-08 Toyobo Co Ltd 核酸またはタンパク質抽出用シリカ粒子組成物
US7465562B2 (en) 2003-05-19 2008-12-16 Brandeis University Nucleic acid processing methods, kits and devices
JP4612789B2 (ja) * 2003-05-29 2011-01-12 キヤノン株式会社 Ｄｎａハイブリッド及びｄｎａハイブリッドを用いた環境浄化システム
WO2004108925A1 (en) * 2003-06-04 2004-12-16 Qiagen As Method for sequentially isolating dna and rna from the same nucleic acid-containing sample
US20050042660A1 (en) * 2003-07-31 2005-02-24 Hall Gerald Edward Devices and methods for isolating RNA
GB0319671D0 (en) * 2003-08-21 2003-09-24 Secr Defence Apparatus for processing a fluid sample
EP1510577A1 (en) * 2003-08-29 2005-03-02 Qiagen GmbH Method for magnetic bead isolation of nucleic acids
WO2005029705A2 (en) * 2003-09-18 2005-03-31 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
ES2375962T3 (es) * 2003-09-22 2012-03-07 Bioarray Solutions Ltd Polielectrolito inmovilizado en superficie con múltiples grupos funcionales capaces de unirse covalentemente a biomoléculas.
JP2007521017A (ja) * 2003-10-28 2007-08-02 バイオアレイ ソリューションズ リミテッド 固定化捕捉プローブを用いる遺伝子発現分析法の最適化
US20050089916A1 (en) * 2003-10-28 2005-04-28 Xiongwu Xia Allele assignment and probe selection in multiplexed assays of polymorphic targets
CN1882703B (zh) 2003-10-29 2011-07-06 佰尔瑞溶液有限公司 通过断裂双链脱氧核糖核酸进行多元核酸分析
US20050106577A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Cleavable solid phases for isolating nucleic acids
US20050106576A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Methods of using cleavable solid phases for isolating nucleic acids
US20050136477A1 (en) * 2003-11-17 2005-06-23 Hashem Akhavan-Tafti Methods for isolating nucleic acids from biological and cellular materials
US20050106589A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Compositions and methods for releasing nucleic acids from solid phase binding materials
US20050106602A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Simplified methods for isolating nucleic acids from cellular materials
DE10358137A1 (de) * 2003-12-12 2005-07-07 Merck Patent Gmbh Verfahren und Kit zur Isolierung von RNA
KR20060129340A (ko) * 2003-12-30 2006-12-15 시그마-알드리치컴퍼니 효소 소화에 의한 핵산의 신속한 제조
EP1715953A1 (en) * 2004-02-18 2006-11-02 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
US8426126B2 (en) * 2004-03-18 2013-04-23 Applied Biosystems, Llc Modified surfaces as solid supports for nucleic acid purification
US20050239091A1 (en) * 2004-04-23 2005-10-27 Collis Matthew P Extraction of nucleic acids using small diameter magnetically-responsive particles
US20050236299A1 (en) * 2004-04-27 2005-10-27 Mark Weber Folded material containment packages and related methods of packaging folded material products
NL1026271C2 (nl) * 2004-05-26 2005-11-30 Keygene Nv Werkwijze en inrichting voor het isoleren van nucleïnezuur uit nucleïnezuur bevattend materiaal.
US20060024712A1 (en) * 2004-06-25 2006-02-02 Invitrogen Corporation Separation of nucleic acid
JP4476050B2 (ja) * 2004-06-30 2010-06-09 株式会社ニデック 視野計
US7363170B2 (en) * 2004-07-09 2008-04-22 Bio Array Solutions Ltd. Transfusion registry network providing real-time interaction between users and providers of genetically characterized blood products
JP4798971B2 (ja) * 2004-07-30 2011-10-19 キヤノン株式会社 磁性粒子集合体およびそれを用いた標的核酸の抽出装置および抽出方法
US7527929B2 (en) 2004-07-30 2009-05-05 Agencourt Bioscience Corporation Methods of isolating nucleic acids using multifunctional group-coated solid phase carriers
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
EP1773865A1 (en) * 2004-08-03 2007-04-18 Becton, Dickinson and Company Use of magnetic material to fractionate samples
CA2839092C (en) * 2004-08-03 2018-04-03 Becton, Dickinson And Company Use of magnetic material to direct isolation of compounds and fractionation of multipart samples
US20080193912A1 (en) 2004-08-03 2008-08-14 Yiu-Lian Fong Compositions and Methods for Preparation of Nucleic Acids from Microbial Samples
EP1623996A1 (en) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved method of selecting a desired protein from a library
US20060099605A1 (en) * 2004-11-11 2006-05-11 Hall Gerald E Jr Devices and methods for isolating RNA
US7320891B2 (en) * 2004-09-10 2008-01-22 Promega Corporation Methods and kits for isolating sperm cells
US7166680B2 (en) * 2004-10-06 2007-01-23 Advanced Cardiovascular Systems, Inc. Blends of poly(ester amide) polymers
EP1650297B1 (en) * 2004-10-19 2011-04-13 Samsung Electronics Co., Ltd. Method and apparatus for the rapid disruption of cells or viruses using micro magnetic beads and laser
DE102005002343A1 (de) 2005-01-18 2006-07-27 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur spezifischen oder unspezifischen Separation von Zellen und/oder Viren aus flüssigen Medien und dessen Verwendung
US7964380B2 (en) * 2005-01-21 2011-06-21 Argylia Technologies Nanoparticles for manipulation of biopolymers and methods of thereof
US20060166223A1 (en) * 2005-01-26 2006-07-27 Reed Michael W DNA purification and analysis on nanoengineered surfaces
EP1690938A1 (de) * 2005-02-11 2006-08-16 Qiagen GmbH Verfahren zur Isolierung von Nukleinsäuren, wobei die Nukleinsäuren bei erhöhter Temperatur an einer Matrix immobilisiert werden
US7914982B2 (en) * 2005-02-17 2011-03-29 Trovagene, Inc. Methods for detecting pathogen specific nucleic acids in urine
ITRM20050067A1 (it) * 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine.
ITRM20050068A1 (it) * 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine.
US20060223071A1 (en) * 2005-04-01 2006-10-05 Wisniewski Michele E Methods, compositions, and kits for detecting nucleic acids in a single vessel
US8628918B2 (en) * 2005-05-09 2014-01-14 Affymetrix, Inc. Multiplex capture of nucleic acids
US8632970B2 (en) * 2005-05-09 2014-01-21 Affymetrix, Inc. Multiplex capture of nucleic acids
ATE502120T1 (de) * 2005-05-12 2011-04-15 Affymetrix Inc Multiplex-assays für verzweigtkettige dna
US20060269929A1 (en) * 2005-05-26 2006-11-30 Hall Gerald E Jr Methods and kits for DNA purification on polymeric membranes at low ionic strength
US20060270843A1 (en) * 2005-05-26 2006-11-30 Hall Gerald E Jr Methods for isolation of nucleic acids
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
EP2460893B1 (en) * 2005-06-20 2013-08-28 Advanced Cell Diagnostics, Inc. Multiplex detection of nucleic acids
CA2613094A1 (en) * 2005-07-01 2007-01-11 Promega Corporation Network of buoyant particles for biomolecule purification
US20070072195A1 (en) * 2005-09-29 2007-03-29 Constantine Haralambopoulos Bio-commemorative article incorporating amplified genetic material
WO2007044427A2 (en) * 2005-10-05 2007-04-19 Panomics, Inc. Detection of nucleic acids from whole blood
US7754148B2 (en) 2006-12-27 2010-07-13 Progentech Limited Instrument for cassette for sample preparation
US7727473B2 (en) 2005-10-19 2010-06-01 Progentech Limited Cassette for sample preparation
US20070092403A1 (en) * 2005-10-21 2007-04-26 Alan Wirbisky Compact apparatus, compositions and methods for purifying nucleic acids
US8030034B2 (en) * 2005-12-09 2011-10-04 Promega Corporation Nucleic acid purification with a binding matrix
KR101066179B1 (ko) * 2006-02-15 2011-09-21 토소가부시키가이샤 생물재료로부터의 핵산 추출법
US20070254284A1 (en) * 2006-05-01 2007-11-01 Biwei Zhao A nucleic acid detection method
US8163535B2 (en) * 2006-06-26 2012-04-24 Blood Cell Storage, Inc. Devices and processes for nucleic acid extraction
US7608399B2 (en) * 2006-06-26 2009-10-27 Blood Cell Storage, Inc. Device and method for extraction and analysis of nucleic acids from biological samples
EP2054501A4 (en) * 2006-10-06 2010-11-03 Promega Corp METHODS AND KITS FOR ISOLATING CELLS
EP1911844A1 (en) 2006-10-10 2008-04-16 Qiagen GmbH Methods and kit for isolating nucleic acids
EP2140026B1 (en) 2006-11-03 2019-08-14 Siemens Healthcare Diagnostics Inc. Random access method for polymerase chain reaction testing
DE602007010986D1 (de) * 2006-12-13 2011-01-13 Roche Diagnostics Gmbh Verwendung von acetalen zur isolation von nukleinsäuren
ES2394815T3 (es) * 2006-12-13 2013-02-05 F. Hoffmann-La Roche Ag Utilización de TDE para el aislamiento de ácidos nucleicos
JP2011503244A (ja) * 2006-12-21 2011-01-27 インヴィトロジェン ダイナル エーエス 核酸の単離方法またはリン酸化タンパク質の単離方法における粒子およびその使用
US8993292B2 (en) * 2007-01-16 2015-03-31 Applied Biosystems Llc Methods and systems for differential extraction
US7960180B2 (en) * 2007-02-20 2011-06-14 University Of Notre Dame Du Lac Methods and apparatus to capture and release microbe particles using amino-functionalized silica
US20100129878A1 (en) * 2007-04-25 2010-05-27 Parthasarathy Ranjani V Methods for nucleic acid amplification
WO2009006417A2 (en) * 2007-06-29 2009-01-08 Becton, Dickinson And Company Methods for extraction and purification of components of biological samples
US7868145B2 (en) * 2007-07-11 2011-01-11 Industrial Technology Research Institute Magnetic particles containing a copolymer core, magnetic layer and silicon layer
US8969044B2 (en) 2007-07-23 2015-03-03 Life Technologies Corporation Method for recovering sperm nucleic acid from a forensic sample
DK2195450T4 (en) * 2007-08-22 2016-10-24 Trovagene Inc Methods of using miRNA FOR DETECTION IN VIVO cell death
CN101363045B (zh) * 2007-09-10 2012-10-17 厦门致善生物科技有限公司 一种用超微磁颗粒分离纯化生物靶物质的方法
US9388457B2 (en) 2007-09-14 2016-07-12 Affymetrix, Inc. Locus specific amplification using array probes
US8357296B2 (en) * 2007-09-24 2013-01-22 Emd Millipore Corporation Centrifugal filter
JP2011504592A (ja) * 2007-11-26 2011-02-10 アトノミックス アクティーゼルスカブ 双峰性サイズ分布を有する磁気粒子を備える、統合型分離および検出カートリッジ
WO2009088987A2 (en) 2008-01-03 2009-07-16 The Johns Hopkins University Compositions and methods for polynucleotide extraction and methylation detection
KR101053023B1 (ko) * 2008-02-14 2011-08-01 (주)바이오니아 구형 실리카 자성입자 및 이의 제조방법
US9074244B2 (en) 2008-03-11 2015-07-07 Affymetrix, Inc. Array-based translocation and rearrangement assays
US20120149587A1 (en) * 2008-03-12 2012-06-14 University Of Virginia Patent Foundation Method for detecting nucleated cells
EP2265942B1 (en) 2008-03-12 2017-10-18 University Of Virginia Patent Foundation Detection of polymeric analytes
DE102008029356A1 (de) * 2008-06-20 2009-12-24 Siemens Healthcare Diagnostics Gmbh Verfahren zur Aufreinigung von Nukleinsäuren, insbesondere aus fixiertem Gewebe
EP2147981A1 (en) * 2008-07-25 2010-01-27 Biotype AG Kit and method for evaluating detection properties in amplification reactions
US20100062518A1 (en) * 2008-09-09 2010-03-11 Sukanta Banerjee Concentrating White Blood Cells for DNA Extraction from a Leukodepleted Blood Sample
WO2010040108A2 (en) * 2008-10-03 2010-04-08 Board Of Regents, The University Of Texas System Method for measuring carbon nanotube taken-up by a plurality of living cells
EP2362907A4 (en) * 2008-11-04 2012-08-08 Blood Cell Storage Inc NUCLEAR ACID EXTRACTION ON DOVED GLASS SURFACES
US8846878B1 (en) 2009-01-23 2014-09-30 Cubrc Corporation Method and device for isolating a protein sample
EP2391725A4 (en) * 2009-01-30 2013-01-02 Us Health METHOD AND SYSTEMS FOR CLEANING TRANSMITTING AND / OR MANIPULATING NUCLEIC ACIDS
DE102009001864A1 (de) * 2009-03-25 2010-09-30 Qiagen Gmbh Überschichtung zur Partikelabtrennung
DE102009022512A1 (de) * 2009-05-25 2010-12-02 Qiagen Gmbh Verfahren zur Reaktivierung von Silikaoberflächen zur Isolierung von Nukleinsäuren
US8039613B2 (en) 2009-08-28 2011-10-18 Promega Corporation Methods of purifying a nucleic acid and formulation and kit for use in performing such methods
US8222397B2 (en) 2009-08-28 2012-07-17 Promega Corporation Methods of optimal purification of nucleic acids and kit for use in performing such methods
TW201113523A (en) * 2009-08-31 2011-04-16 Mbio Diagnostics Inc Integrated sample preparation and analyte detection
US11096345B2 (en) 2009-09-01 2021-08-24 Basf Se Method for treating post-emergent rice
TW201113376A (en) 2009-09-01 2011-04-16 Basf Agrochemical Products Bv Herbicide-tolerant plants
TWI407994B (zh) 2009-10-22 2013-09-11 Ind Tech Res Inst 分離核酸的方法、試劑及套組
WO2011077333A1 (en) * 2009-12-23 2011-06-30 Koninklijke Philips Electronics N.V. Analyte measurement apparatus and method
EP2345719A1 (en) 2010-01-18 2011-07-20 Qiagen GmbH Method for isolating small RNA
KR101643196B1 (ko) 2010-02-23 2016-07-27 루미넥스 코포레이션 일체화된 샘플 제조, 반응 및 검출을 위한 장치 및 방법
US20110223588A1 (en) * 2010-03-09 2011-09-15 Biosample Llc Solid Phase Nucleic Acid Extraction From Small Sample Volumes, and Release of Controlled Quantities
EP2407540A1 (en) 2010-07-15 2012-01-18 Qiagen GmbH Method for purifying a target nucleic acid
DE102010036111B4 (de) 2010-09-01 2013-08-29 Bundesrepublik Deutschland (Bundesamt für Ausrüstung, Informationstechnik und Nutzung der Bundeswehr) Vorbehandlungsverfahren zur Isolierung und Aufkonzentrierung von Nukleinsäuren aus einer Umweltprobe
ES2562821T3 (es) 2010-10-21 2016-03-08 Advanced Cell Diagnostics, Inc. Método ultrasensible para la detección in situ de ácidos nucleicos
US20120149088A1 (en) 2010-11-30 2012-06-14 Life Technologies Corporation Alkylene glycols and polymers and copolymers thereof for direct isolation of nucleic acid from embedded samples
BR112013014778A2 (pt) 2010-12-16 2017-06-06 Basf Se método para controlar a vegetação indesejável em um sítio de cultivo de plantas, método para identificar uma herbicida derivado de benzoxazinona, método de identificação de uma sequência de nucleotídeos, ácido nucleico isolado, célula vegetal transgênica, planta transgênica e semente
EP2465934A1 (de) 2010-12-20 2012-06-20 Steffen Mergemeier Extraktion von Nukleinsäuren
US9051563B2 (en) 2011-01-14 2015-06-09 Zymo Research Corporation Nucleic acid purification
CN107338189B (zh) 2011-05-04 2021-02-02 卢米耐克斯公司 用于集成的样品制备、反应和检测的设备与方法
US8629264B2 (en) 2011-05-19 2014-01-14 Blood Cell Storage, Inc. Gravity flow fluidic device for nucleic acid extraction
US9304070B2 (en) 2011-07-13 2016-04-05 Emd Millipore Corporation All-in-one sample preparation device and method
DE102011054474B4 (de) 2011-07-20 2014-02-13 Stratec Biomedical Ag System zur Stabilisierung, Aufbewahrung und Lagerung einer Nukleinsäure
US9695465B2 (en) 2011-08-12 2017-07-04 Qiagen Gmbh Method for isolating nucleic acids
CA2863215C (en) 2012-01-30 2021-05-04 Exact Sciences Corporation Modification of dna on magnetic beads
EP2634254A1 (en) 2012-02-29 2013-09-04 QIAGEN GmbH Method for isolating nucleic acids from a food sample
AR091489A1 (es) 2012-06-19 2015-02-11 Basf Se Plantas que tienen una mayor tolerancia a herbicidas inhibidores de la protoporfirinogeno oxidasa (ppo)
US10041087B2 (en) 2012-06-19 2018-08-07 BASF Agro B.V. Plants having increased tolerance to herbicides
IN2014DN11074A (pt) 2012-06-25 2015-09-25 Gen Hospital Corp
EP2770056B1 (en) 2012-07-18 2017-05-31 Zymo Research Corporation Nucleic acid purification
FR2994184B1 (fr) 2012-08-02 2017-12-08 Biomerieux Sa Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits
EP2888363B1 (en) 2012-08-21 2018-06-06 Qiagen GmbH Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
EP2888354B1 (en) 2012-08-21 2020-04-01 Qiagen GmbH Virus particle stabilisation and method for isolating viral nucleic acids
SG10201701747YA (en) 2012-09-03 2017-04-27 Qiagen Gmbh Method for isolating rna including small rna with high yield
CA2885263C (en) 2012-09-17 2021-11-16 W. R. Grace & Co.-Conn. Chromatography media and devices
GB201217405D0 (en) * 2012-09-28 2012-11-14 Fermentas Uab Protein removal agent
WO2014122288A1 (en) 2013-02-08 2014-08-14 Qiagen Gmbh Method for separating dna by size
CN105190312B (zh) 2013-03-01 2017-12-12 斯彼诺米克斯公司 基于磁性粒子的分离和测定方法
CN105378108A (zh) * 2013-03-13 2016-03-02 雅培分子公司 用于分离核酸的系统和方法
US9670479B2 (en) 2013-03-15 2017-06-06 F Cubed, LLC Sample preparation device and methods of use
JP5802237B2 (ja) * 2013-04-18 2015-10-28 三洋化成工業株式会社 磁性粒子及びその製造方法
WO2015022639A2 (en) 2013-08-12 2015-02-19 Basf Se Plants having increased tolerance to herbicides
EP3033426A4 (en) 2013-08-12 2017-08-02 BASF Agro B.V. Plants having increased tolerance to herbicides
DE202014002379U1 (de) 2014-03-15 2014-08-19 Ruprecht-Karls-Universität Heidelberg DNA Stabilisierungssystem
WO2015150465A2 (en) 2014-04-03 2015-10-08 Basf Se Plants having increased tolerance to herbicides
CN107847907A (zh) 2014-05-02 2018-03-27 格雷斯公司 官能化载体材料以及制备和使用官能化载体材料的方法
WO2015199423A1 (ko) * 2014-06-24 2015-12-30 (주)바이오니아 자성 입자를 이용한 핵산 분리 방법
US10000750B2 (en) 2014-10-09 2018-06-19 Promega Corporation Method of isolating nucleic acid
CN107112105A (zh) 2014-10-23 2017-08-29 康宁股份有限公司 聚合物包封的磁性纳米颗粒
JP6773402B2 (ja) * 2014-11-04 2020-10-21 三洋化成工業株式会社 磁性シリカ粒子を用いた対象物質の分離方法
EP3059312A1 (en) 2015-02-20 2016-08-24 QIAGEN GmbH Nucleic acid extraction method
US9422596B1 (en) 2015-04-27 2016-08-23 Norgen Biotek Corp. Methods and columns for nucleic acid purification
KR101646610B1 (ko) * 2015-05-28 2016-08-09 (주)바이오니아 생체 물질 정제용 고활성 실리카 자성나노입자 및 이의 제조 방법
WO2016193282A1 (en) 2015-06-01 2016-12-08 Qiagen Gmbh Electrophoresis assisted method for purifying a target nucleic acid using a delayed elution approach
EP3303582A1 (en) 2015-06-01 2018-04-11 Qiagen GmbH Electrophoresis assisted method and device for purifying a charged target molecule from a sample
PL3302784T3 (pl) 2015-06-05 2022-01-17 W.R. Grace & Co.-Conn. Adsorbentowe środki klarujące do bioprzetwarzania oraz sposoby ich wytwarzania i stosowania
JP7007197B2 (ja) 2015-06-05 2022-01-24 キアゲン ゲーエムベーハー サイズによってｄｎａを分離する方法
CN108026570A (zh) * 2015-09-11 2018-05-11 康宁股份有限公司 从血液样品中纯化核酸的组合物和方法
EP3913068B1 (en) 2015-10-12 2023-08-02 Advanced Cell Diagnostics, Inc. In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto
EP3448990B1 (en) 2016-04-29 2021-06-09 BASF Plant Science Company GmbH Methods for modification of target nucleic acids using a fusion molecule of guide and donor rna, fusion rna molecule and vector systems encoding the fusion rna molecule
TR201606310A2 (tr) 2016-05-12 2017-11-21 Akdeniz Ueniversitesi Genomik dna izolasyon yöntemi ve kiti.
CA3024770A1 (en) 2016-05-20 2017-11-23 BASF Agro B.V. Dual transit peptides for targeting polypeptides
US20200308631A1 (en) 2016-06-30 2020-10-01 Biois Co., Ltd Double-stranded nucleic acid signal probe and method for detecting target molecule using same
BR112019001483A2 (pt) 2016-07-27 2019-09-10 Basf Agro Bv método para controlar a vegetação indesejada em um local de cultivo de plantas
US10077465B2 (en) * 2016-09-13 2018-09-18 The United States Of America, As Represented By The Secretary Of The Navy Sorbents for extraction and stabilization of nucleic acids
EP3519093B1 (en) 2016-09-30 2021-03-10 Koninklijke Philips N.V. System for applying a reagent to a sample
CA3043489A1 (en) 2016-11-21 2018-05-24 Nanostring Technologies, Inc. Chemical compositions and methods of using same
MX2019007469A (es) 2016-12-20 2020-02-07 Basf Agro Bv Plantas que tienen una mayor tolerancia a herbicidas.
US11891599B2 (en) * 2017-05-22 2024-02-06 Qiagen Healthcare Biotechnologies Systems Gmbh Recovery of nucleic acids from solid supports
WO2019063071A1 (en) 2017-09-27 2019-04-04 Qiagen Gmbh METHOD FOR HIGH-PERFORMANCE RNA ISOLATION
EP3794146A1 (en) 2018-05-14 2021-03-24 Nanostring Technologies, Inc. Chemical compositions and methods of using same
JP7428657B2 (ja) * 2018-10-26 2024-02-06 テルモ株式会社 標的物質の分離方法および定量方法
US20220276270A1 (en) * 2019-05-08 2022-09-01 Hitachi High-Tech Corporation Pretreatment method of an automatic analyzer
US11807909B1 (en) 2019-09-12 2023-11-07 Zymo Research Corporation Methods for species-level resolution of microorganisms
WO2021100801A1 (ja) * 2019-11-20 2021-05-27 東レ株式会社 核酸の分離方法、検出方法、核酸精製カラム及びその製造方法
EP4163397A1 (en) 2020-06-05 2023-04-12 Seegene, Inc. Specimen transport kit for detecting respiratory pathogens and methods for detecting respiratory pathogens using same
KR20220075978A (ko) 2020-11-30 2022-06-08 (주)바이오니아 중저 비유전율을 가진 화합물을 포함한 핵산 결합 완충액을 이용한 핵산 분리방법
WO2023075394A1 (ko) 2021-10-29 2023-05-04 주식회사 씨젠 검체 채취 스왑 도구 및 호흡기 병원체의 검출 방법

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395271A (en) * 1979-04-13 1983-07-26 Corning Glass Works Method for making porous magnetic glass and crystal-containing structures
US4297337A (en) * 1979-04-13 1981-10-27 Corning Glass Works Solid-phase immunoassays using magnetic glass
US4233169A (en) * 1979-04-13 1980-11-11 Corning Glass Works Porous magnetic glass structure
DE3211309A1 (de) 1982-03-26 1983-09-29 Metin Dipl.-Ing. 6100 Darmstadt Colpan Chromatographisches verfahren zur isolierung von makromolekuelen
US5482834A (en) 1982-05-17 1996-01-09 Hahnemann University Evaluation of nucleic acids in a biological sample hybridization in a solution of chaotrophic salt solubilized cells
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US4672040A (en) 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
US4695393A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5076950A (en) * 1985-12-20 1991-12-31 Syntex (U.S.A.) Inc. Magnetic composition for particle separation
US6027750A (en) * 1986-09-04 2000-02-22 Gautsch; James Systems and methods for the rapid isolation of nucleic acids
DE3639949A1 (de) 1986-11-22 1988-06-09 Diagen Inst Molekularbio Verfahren zur trennung von langkettigen nukleinsaeuren
US4767670A (en) 1987-01-21 1988-08-30 E. I. Du Pont De Nemours And Company Chromatographic supports for separation of oligonucleotides
DE68920778T2 (de) * 1988-05-24 1995-05-18 Anagen Uk Ltd Magnetisch anziehbare Teilchen und Herstellungsverfahren.
US5512439A (en) * 1988-11-21 1996-04-30 Dynal As Oligonucleotide-linked magnetic particles and uses thereof
US5075430A (en) * 1988-12-12 1991-12-24 Bio-Rad Laboratories, Inc. Process for the purification of DNA on diatomaceous earth
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5523231A (en) 1990-02-13 1996-06-04 Amersham International Plc Method to isolate macromolecules using magnetically attractable beads which do not specifically bind the macromolecules
US5243037A (en) * 1990-09-21 1993-09-07 E. I. Du Pont De Nemours And Company Poly(fluoroalkyl) sugar reagents for surface modification of supports
WO1992011933A1 (en) 1991-01-04 1992-07-23 Perseptive Biosystems, Inc. Sulfonamide bonded hydrophilic coatings
US5155018A (en) * 1991-07-10 1992-10-13 Hahnemann University Process and kit for isolating and purifying RNA from biological sources
US5395498A (en) * 1991-11-06 1995-03-07 Gombinsky; Moshe Method for separating biological macromolecules and means therfor
US5610274A (en) * 1991-11-20 1997-03-11 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5734020A (en) 1991-11-20 1998-03-31 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5346994A (en) * 1992-01-28 1994-09-13 Piotr Chomczynski Shelf-stable product and process for isolating RNA, DNA and proteins
DE69324716T2 (de) 1992-02-13 1999-09-09 Becton Dickinson Co Celithydrat und Reinigung von DNS
JP3494646B2 (ja) * 1992-06-08 2004-02-09 ジェン−プローブ・インコーポレイテッド 単核細胞からの核酸の調製
US5316680A (en) 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
JP3615545B2 (ja) 1993-02-01 2005-02-02 キアゲン・エヌ・ブイ 第四級アンモニウム塩界面活性剤及びそのｒｎａの単離剤
DE4307262A1 (de) * 1993-03-02 1994-09-08 Christian Bergemann Magnetisches polymeres Siliciumdioxid
WO1995006652A1 (en) * 1993-08-30 1995-03-09 Promega Corporation Nucleic acid purification compositions and methods
CA2182397C (en) 1994-02-07 2004-04-13 Metin Colpan Endotoxin reduction or removal process
US5990301A (en) 1994-02-07 1999-11-23 Qiagen Gmbh Process for the separation and purification of nucleic acids from biological sources
DE4420732A1 (de) * 1994-06-15 1995-12-21 Boehringer Mannheim Gmbh Vorrichtung zur Behandlung von Nukleinsäuren aus einer Probe
WO1996003653A1 (de) * 1994-07-27 1996-02-08 Silica Gel Ges.Mbh Absorptionstechnik, Apparatebau Superparamagnetische teilchen, verfahren zur herstellung und deren verwendung
US5582988A (en) 1994-09-15 1996-12-10 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same
US5652348A (en) 1994-09-23 1997-07-29 Massey University Chromatographic resins and methods for using same
US5660984A (en) * 1994-12-09 1997-08-26 Davis; Thomas E. DNA isolating apparatus comprising a non-porous DNA binding, anion exchange resin and methods of use thereof
DE19520398B4 (de) * 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
JP2965131B2 (ja) * 1995-07-07 1999-10-18 東洋紡績株式会社 核酸結合用磁性担体およびそれを用いる核酸単離方法
US5783686A (en) * 1995-09-15 1998-07-21 Beckman Instruments, Inc. Method for purifying nucleic acids from heterogenous mixtures
SE9600590D0 (sv) 1996-02-19 1996-02-19 Pharmacia Biotech Ab Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris
US5904848A (en) 1996-02-21 1999-05-18 Cpg, Inc. Controlled pore glass-synthetic resin membrane
CA2248981C (en) * 1996-03-15 2009-11-24 The Penn State Research Foundation Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays
JP3940935B2 (ja) * 1996-06-11 2007-07-04 東洋紡績株式会社 プラスミドｄｎａの抽出精製方法
JPH09327291A (ja) * 1996-06-11 1997-12-22 Toyobo Co Ltd Ｒｎａの抽出精製方法
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
ATE229371T1 (de) 1997-01-21 2002-12-15 Grace W R & Co Siliciumdioxidadsorbent auf magnetischem träger
JP4196227B2 (ja) 1997-05-20 2008-12-17 東洋紡績株式会社 核酸またはタンパク質抽出用シリカ粒子組成物
US6410725B1 (en) * 1999-02-26 2002-06-25 Myriad Genetics Inc. Method for extracting DNA from dried specimens

Also Published As

Publication number Publication date
DE69841555D1 (de) 2010-04-22
EP1367137B1 (en) 2010-03-10
US6027945A (en) 2000-02-22
US6368800B1 (en) 2002-04-09
DE69817484D1 (de) 2003-10-02
AU732756B2 (en) 2001-04-26
US20040086930A1 (en) 2004-05-06
EP0895546B1 (en) 2003-08-27
AU6647598A (en) 1998-08-07
US20020086326A1 (en) 2002-07-04
EP0895546A1 (en) 1999-02-10
DE895546T1 (de) 2002-10-17
US6673631B1 (en) 2004-01-06
EP0895546A4 (en) 2002-03-20
CA2249393A1 (en) 1998-07-23
JP3253638B2 (ja) 2002-02-04
DE69817484T2 (de) 2004-06-17
WO1998031840A1 (en) 1998-07-23
EP1367137A1 (en) 2003-12-03
JPH11509742A (ja) 1999-08-31
DK1367137T3 (da) 2010-07-12

Similar Documents

Publication Publication Date Title
BR9805897A (pt) M-todos de isolamento de materiais alvo biolÄgicos que utilizam part¡culas magne-ticas de s¡lica
DE69838515D1 (de) Aminothiazole zur hemmung cyclinabhängiger kinasen
AU8781898A (en) Ventilated cage for laboratory animal
DE69831358D1 (de) System und verfahren zur vereinfachung des weiterreichens
PT1002244E (pt) Metodo de preparacao de materiais para dispositivos oftalmicos dobraveis acrilicos de elevado indicerefractivo
DE69832349D1 (de) Verfahren zur Herstellung von gebundenen Zeolithen
DE69813349D1 (de) Vorrichtung zur Kontrolle der Datenmenge und Kodierer dieselbige anwendend
DE69504362D1 (de) Vorrichtung zur übertragung des bremsmomentes einer flugzeugbremse
DE69832968D1 (de) Werkzeug zur reibungsminderung
NO20011126L (no) Pulveriserer samt fremgangsmåte ved pulverisering
DE69522019D1 (de) Einteilige Vorrichtung zur Aufbereitung von biologischen Proben
AU4158797A (en) Screening assay for the identification of agents which alter expression of pth-rp
GB2341092B (en) Composition for the removal of biological and organic substances
ATE268998T1 (de) Verfahren zur erhöhung der reproduzierenden leistung von hunden und katzen
AU8898198A (en) Methods of identifying biological agent compositions
PT998470E (pt) Processo de preparacao de derivados aminados de alquiloxifuranona compostos provenientes desse processo e utilizacao desses compostos
DE29709099U1 (de) Vorrichtung zur Detektion elektromagneticher Störquellen
AU2002218460A8 (en) Transportation of biological specimens
GB2276088B (en) An isolator for laboratory animals
DE69830744D1 (de) Vorrichtung zur steuerung der verstärkung der photonenstrahlungsdosis
BR9804794A (pt) Processo para prepara-Æo de 1-alquil-4-(2-cloro-3-alcÄxi-4-alquil-sulfonil-benzoil) -5-hidrÄxi-pirazol e compostos relacioonados
DE29719093U1 (de) Vorrichtung zur physischen Simulation virtueller Räume
DE69809421T2 (de) Einrichtung zur steuerung eines im winkel bewegbaren teils
IT1290457B1 (it) Processo per la preparazione di tetraazamacrocicli
DE29714382U1 (de) Vorrichtung zur drahtlosen Betätigung von Anlagen

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1905 DE 10/07/2007.