FR2994184B1 - Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits - Google Patents

Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits

Info

Publication number
FR2994184B1
FR2994184B1 FR1257526A FR1257526A FR2994184B1 FR 2994184 B1 FR2994184 B1 FR 2994184B1 FR 1257526 A FR1257526 A FR 1257526A FR 1257526 A FR1257526 A FR 1257526A FR 2994184 B1 FR2994184 B1 FR 2994184B1
Authority
FR
France
Prior art keywords
methods
functionalization
aza
kits
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1257526A
Other languages
English (en)
Other versions
FR2994184A1 (fr
Inventor
Thomas Cailly
Frederic Fabis
Ali Laayoun
Alain Laurent
Sylvain Ursuegui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Original Assignee
Biomerieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux SA filed Critical Biomerieux SA
Priority to FR1257526A priority Critical patent/FR2994184B1/fr
Priority to EP13744493.1A priority patent/EP2880016A1/fr
Priority to PCT/EP2013/065854 priority patent/WO2014019966A1/fr
Priority to US14/416,996 priority patent/US10174068B2/en
Priority to JP2015524746A priority patent/JP6407151B2/ja
Publication of FR2994184A1 publication Critical patent/FR2994184A1/fr
Application granted granted Critical
Publication of FR2994184B1 publication Critical patent/FR2994184B1/fr
Priority to US16/217,483 priority patent/US20190112329A1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR1257526A 2012-08-02 2012-08-02 Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits Expired - Fee Related FR2994184B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR1257526A FR2994184B1 (fr) 2012-08-02 2012-08-02 Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits
EP13744493.1A EP2880016A1 (fr) 2012-08-02 2013-07-26 Procedes de fonctionnalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoïque ou un de ses derives, molecules biologiques ainsi traitees et kits
PCT/EP2013/065854 WO2014019966A1 (fr) 2012-08-02 2013-07-26 Procedes de fonctionnalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoïque ou un de ses derives, molecules biologiques ainsi traitees et kits
US14/416,996 US10174068B2 (en) 2012-08-02 2013-07-26 Methods of functionalization and reagents used in such methods using an aza-isatoic anhydride or a derivative thereof, biological molecules thus treated and kits
JP2015524746A JP6407151B2 (ja) 2012-08-02 2013-07-26 アザイサト酸無水物又はその誘導体の一つを用いた官能化の方法及びこの方法において使用される試薬、このように処置された生物学的分子及びキット
US16/217,483 US20190112329A1 (en) 2012-08-02 2018-12-12 Methods of functionalization and reagents used in such methods using an aza-isatoic anhydride or a derivative thereof, biological molecules thus treated and kits

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1257526A FR2994184B1 (fr) 2012-08-02 2012-08-02 Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits

Publications (2)

Publication Number Publication Date
FR2994184A1 FR2994184A1 (fr) 2014-02-07
FR2994184B1 true FR2994184B1 (fr) 2017-12-08

Family

ID=46963941

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1257526A Expired - Fee Related FR2994184B1 (fr) 2012-08-02 2012-08-02 Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits

Country Status (5)

Country Link
US (2) US10174068B2 (fr)
EP (1) EP2880016A1 (fr)
JP (1) JP6407151B2 (fr)
FR (1) FR2994184B1 (fr)
WO (1) WO2014019966A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3053968A1 (fr) * 2016-07-13 2018-01-19 Biomerieux Reactifs pour la protection reversible de molecules biologiques
IL297543A (en) 2017-11-30 2022-12-01 Arrakis Therapeutics Inc Nucleic acid-binding photoprobes and their uses

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1060102A (fr) 1951-12-08 1954-03-30 Sawyer S Inc Support de vues stéréoscopiques dispositives et son procédé de labrication
US3838120A (en) * 1972-12-07 1974-09-24 Sterling Drug Inc 1-alkyl-1h,4h-pyrido(2,3-d)(1,3)oxazine-2,4-diones and their conversion to 1-alkyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids
ATE48140T1 (de) 1981-04-17 1989-12-15 Univ Yale Modifizierte nukleotide und verfahren zu ihrer herstellung und anwendung.
CA1219824A (fr) 1981-04-17 1987-03-31 David C. Ward Nucleotides modifies, leur preparation et leur emploi
US4711955A (en) 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
CA1223831A (fr) 1982-06-23 1987-07-07 Dean Engelhardt Nucleotides modifies, methodes de preparation et d'utilisation et composes les contenant
DE3910151A1 (de) 1989-03-29 1990-10-04 Toni Dr Lindl 5'-bromo-2'-desoxyuridinmarkierte dna- oder rna- sonden
WO1993016094A2 (fr) 1992-02-12 1993-08-19 Chromagen, Inc. Utilisation de n-nucleosides fluorescents et de leurs analogues structurels fluorescents
DE4213703A1 (de) 1992-04-25 1993-10-28 Merck Patent Gmbh Fluoreszenzmarkierte Verbindungen, ihre Herstellung und Verwendung
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
US6794140B1 (en) 1999-04-30 2004-09-21 Andrew Simon Goldsborough Isolation of nucleic acid
DE60137203D1 (de) 2000-03-24 2009-02-12 Qiagen Gmbh Poröse ferro- oder ferrimagnetische glasteilchen für molekültrennung
GB0024807D0 (en) 2000-10-10 2000-11-22 Smithkline Beecham Plc Novel compounds
FR2824323B1 (fr) 2001-05-04 2008-04-25 Bio Merieux Reactif de marquage et procede de detection de molecules biologiques
ATE449186T1 (de) 2001-11-28 2009-12-15 Applied Biosystems Llc Zusammensetzungen und verfahren zur selektiven nukleinsäureisolierung
SE0200543D0 (sv) 2002-02-21 2002-02-21 Amersham Biosciences Ab Method of separation using aromatic thioether ligands
GB0217963D0 (en) 2002-08-02 2002-09-11 Cyclops Genome Sciences Ltd Purification of nucleic acids
US7902203B2 (en) * 2002-11-01 2011-03-08 Abbott Laboratories, Inc. Anti-infective agents
WO2004064759A2 (fr) * 2003-01-21 2004-08-05 Chiron Corporation Utilisation de composes de tryptanthrine dans la potentialisation immunologique
JP4241183B2 (ja) 2003-05-19 2009-03-18 株式会社日立ハイテクノロジーズ 核酸回収方法及び核酸回収キット
EP1510577A1 (fr) 2003-08-29 2005-03-02 Qiagen GmbH Méthode pour l'isolation des acides nucléiques en utilisant des particules magnétiques
US20050106576A1 (en) 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Methods of using cleavable solid phases for isolating nucleic acids
US20050106577A1 (en) 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Cleavable solid phases for isolating nucleic acids
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FR2868071B1 (fr) 2004-03-26 2006-06-09 Biomerieux Sa Reactifs de marquage, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
US20050239091A1 (en) 2004-04-23 2005-10-27 Collis Matthew P Extraction of nucleic acids using small diameter magnetically-responsive particles
DE102004034433A1 (de) 2004-07-15 2006-02-02 Qiagen Gmbh Verfahren zur Reinigung und Isolierung von Nukleinsäuren unter Verwendung kationischer Detergentien
DE102005015005A1 (de) 2005-04-01 2006-10-05 Qiagen Gmbh Verfahren zur Behandlung einer Biomoleküle enthaltenden Probe
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FR2934595B1 (fr) 2008-07-29 2013-04-05 Biomerieux Sa Reactifs de marquage ayant un noyau pyridine portant une fonction diazomethyle, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
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Also Published As

Publication number Publication date
US20150210732A1 (en) 2015-07-30
JP2015526076A (ja) 2015-09-10
US20190112329A1 (en) 2019-04-18
FR2994184A1 (fr) 2014-02-07
JP6407151B2 (ja) 2018-10-17
US10174068B2 (en) 2019-01-08
WO2014019966A1 (fr) 2014-02-06
EP2880016A1 (fr) 2015-06-10

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FR2994184B1 (fr) Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits

Legal Events

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Year of fee payment: 5

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Effective date: 20200406