ATE419919T1 - System und verfahren zur behandlung von magnetpartikeln in test-flüssigkeiten zum sammeln von dna und rna - Google Patents
System und verfahren zur behandlung von magnetpartikeln in test-flüssigkeiten zum sammeln von dna und rnaInfo
- Publication number
- ATE419919T1 ATE419919T1 AT01937472T AT01937472T ATE419919T1 AT E419919 T1 ATE419919 T1 AT E419919T1 AT 01937472 T AT01937472 T AT 01937472T AT 01937472 T AT01937472 T AT 01937472T AT E419919 T1 ATE419919 T1 AT E419919T1
- Authority
- AT
- Austria
- Prior art keywords
- particles
- solution
- nucleic acid
- acid molecules
- magnetic particles
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/103—General features of the devices using disposable tips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57354000A | 2000-05-19 | 2000-05-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE419919T1 true ATE419919T1 (de) | 2009-01-15 |
Family
ID=24292405
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01937472T ATE419919T1 (de) | 2000-05-19 | 2001-05-17 | System und verfahren zur behandlung von magnetpartikeln in test-flüssigkeiten zum sammeln von dna und rna |
Country Status (7)
Country | Link |
---|---|
US (1) | US20020008053A1 (de) |
EP (1) | EP1282469B1 (de) |
JP (1) | JP4792192B2 (de) |
AT (1) | ATE419919T1 (de) |
DE (1) | DE60137323D1 (de) |
ES (1) | ES2319101T3 (de) |
WO (1) | WO2001089705A2 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
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US6048734A (en) | 1995-09-15 | 2000-04-11 | The Regents Of The University Of Michigan | Thermal microvalves in a fluid flow method |
US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
US6852287B2 (en) | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
US7323140B2 (en) | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
US7829025B2 (en) * | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
JP2005522679A (ja) * | 2002-04-12 | 2005-07-28 | インストゥルメンテイション ラボラトリー カンパニー | イムノアッセイプローブ |
JP2005523692A (ja) * | 2002-04-26 | 2005-08-11 | アボット・ラボラトリーズ | 生物学的検定において磁性粒子を処理するための構造体および方法 |
EP1506413B1 (de) | 2002-05-17 | 2016-07-06 | Becton Dickinson and Company | Automatisches system zum isolieren, amplifizieren und nachweisen einer zielnukleinsäuresequenz |
SE522099C2 (sv) * | 2002-06-07 | 2004-01-13 | Genovis Ab | Anordning för multipel simultan genöverföring |
US6856163B2 (en) | 2002-09-25 | 2005-02-15 | Marvell World Trade Ltd. | Power supply decoupling for parallel terminated transmission line |
JP4996248B2 (ja) | 2003-07-31 | 2012-08-08 | ハンディーラブ インコーポレイテッド | 粒子含有サンプルの処理 |
WO2005108620A2 (en) * | 2004-05-03 | 2005-11-17 | Handylab, Inc. | Processing polynucleotide-containing samples |
US8852862B2 (en) * | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
US8211386B2 (en) * | 2004-06-08 | 2012-07-03 | Biokit, S.A. | Tapered cuvette and method of collecting magnetic particles |
EP1945815A4 (de) * | 2005-10-11 | 2009-02-18 | Handylab Inc | Polynukleotidprobenvorbereitungsvorrichtung |
US7998708B2 (en) * | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US8883490B2 (en) | 2006-03-24 | 2014-11-11 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
ES2692380T3 (es) | 2006-03-24 | 2018-12-03 | Handylab, Inc. | Método para realizar PCR con un cartucho con varias pistas |
US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
WO2008061165A2 (en) * | 2006-11-14 | 2008-05-22 | Handylab, Inc. | Microfluidic cartridge and method of making same |
US8550523B2 (en) * | 2007-06-22 | 2013-10-08 | Data I/O Corporation | Pick and place system |
US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
AU2008276211B2 (en) * | 2007-07-13 | 2015-01-22 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
AU2013205267B2 (en) * | 2007-07-13 | 2015-08-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US20090027998A1 (en) * | 2007-07-25 | 2009-01-29 | Abbott Laboratories | Magnetic mixer |
US20100009351A1 (en) * | 2008-07-11 | 2010-01-14 | Handylab, Inc. | Polynucleotide Capture Materials, and Method of Using Same |
USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
EP2191900B1 (de) | 2008-11-28 | 2016-03-30 | F. Hoffmann-La Roche AG | System und Verfahren zur Behandlung von Nukleinsäuren enthaltenden Fluiden |
ES2769028T3 (es) | 2011-04-15 | 2020-06-24 | Becton Dickinson Co | Termociclador microfluídico de barrido en tiempo real |
CN102500460B (zh) * | 2011-09-26 | 2014-04-30 | 中国科学院过程工程研究所 | 一种气助超顺磁性萃取方法 |
USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
DK3273253T3 (da) | 2011-09-30 | 2020-10-12 | Becton Dickinson Co | Forenet reagensstrimmel |
CN104040238B (zh) | 2011-11-04 | 2017-06-27 | 汉迪拉布公司 | 多核苷酸样品制备装置 |
CN107881219B (zh) | 2012-02-03 | 2021-09-10 | 贝克顿·迪金森公司 | 用于分子诊断测试分配和测试之间兼容性确定的外部文件 |
CN106367311B (zh) * | 2016-12-08 | 2019-07-12 | 湖南圣湘生物科技有限公司 | 一种核酸提取系统及其使用方法 |
KR20180090543A (ko) * | 2017-02-03 | 2018-08-13 | 주식회사 미코바이오메드 | 생물학적 시료로부터 목적하는 물질을 분리 또는 정제하기 위한 장치 및 방법 |
US11433402B2 (en) * | 2017-07-19 | 2022-09-06 | Amgen Inc. | Magnetic assisted separation apparatuses and related methods |
EP3470141B1 (de) * | 2017-10-11 | 2024-04-24 | F. Hoffmann-La Roche AG | Vorrichtung und verfahren zur verarbeitung einer biologischen probe mit magnetischen partikeln |
CN107988045B (zh) * | 2018-01-08 | 2024-01-19 | 深圳市朗司医疗科技有限公司 | 一种基于磁珠法的全自动核酸纯化系统 |
EP3520893B1 (de) * | 2018-02-02 | 2020-07-22 | F. Hoffmann-La Roche AG | System zur thermisch gesteuerten verarbeitung einer biologischen probe |
JP2019148556A (ja) * | 2018-02-28 | 2019-09-05 | シスメックス株式会社 | Bf分離装置、試料分析装置およびbf分離方法 |
CN108889627A (zh) * | 2018-07-26 | 2018-11-27 | 天津鹏宇兴业五金制品有限公司 | 一种具有减震功能的钢钉筛选装置 |
CN111896760A (zh) * | 2020-07-15 | 2020-11-06 | 宁波华仪宁创智能科技有限公司 | 封闭空间的控制方法及自动进样方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS53136764A (en) * | 1977-05-02 | 1978-11-29 | Fuji Electric Co Ltd | Magnetism separation device |
US5147529A (en) * | 1988-08-10 | 1992-09-15 | E. I. Du Pont De Nemours And Company | Method for automatically processing magnetic solid phase reagents |
GB9323305D0 (en) * | 1993-11-11 | 1994-01-05 | Medinnova Sf | Isoaltion of nucleic acid |
US5686271A (en) * | 1994-06-09 | 1997-11-11 | Gamera Bioscience Corporation | Apparatus for performing magnetic cycle reaction |
US6027945A (en) * | 1997-01-21 | 2000-02-22 | Promega Corporation | Methods of isolating biological target materials using silica magnetic particles |
DE69839294T2 (de) * | 1997-09-29 | 2009-04-09 | F. Hoffmann-La Roche Ag | Gerät zur Abscheidung magnetischer Teilchen |
JPH11326338A (ja) * | 1998-05-18 | 1999-11-26 | Tosoh Corp | 反応テーブル |
ATE303598T1 (de) * | 1998-07-31 | 2005-09-15 | Tecan Trading Ag | Magnetseparator |
US5973138A (en) * | 1998-10-30 | 1999-10-26 | Becton Dickinson And Company | Method for purification and manipulation of nucleic acids using paramagnetic particles |
-
2001
- 2001-05-17 WO PCT/US2001/015882 patent/WO2001089705A2/en active Application Filing
- 2001-05-17 EP EP01937472A patent/EP1282469B1/de not_active Expired - Lifetime
- 2001-05-17 ES ES01937472T patent/ES2319101T3/es not_active Expired - Lifetime
- 2001-05-17 JP JP2001585934A patent/JP4792192B2/ja not_active Expired - Lifetime
- 2001-05-17 DE DE60137323T patent/DE60137323D1/de not_active Expired - Lifetime
- 2001-05-17 AT AT01937472T patent/ATE419919T1/de not_active IP Right Cessation
- 2001-09-21 US US09/960,431 patent/US20020008053A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2004515333A (ja) | 2004-05-27 |
WO2001089705A3 (en) | 2002-03-21 |
US20020008053A1 (en) | 2002-01-24 |
ES2319101T3 (es) | 2009-05-04 |
EP1282469A2 (de) | 2003-02-12 |
EP1282469B1 (de) | 2009-01-07 |
WO2001089705A2 (en) | 2001-11-29 |
JP4792192B2 (ja) | 2011-10-12 |
DE60137323D1 (de) | 2009-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1282469 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |