BR0210460A - métodos de produção de pirrolidonas - Google Patents

métodos de produção de pirrolidonas

Info

Publication number
BR0210460A
BR0210460A BRPI0210460-1A BR0210460A BR0210460A BR 0210460 A BR0210460 A BR 0210460A BR 0210460 A BR0210460 A BR 0210460A BR 0210460 A BR0210460 A BR 0210460A
Authority
BR
Brazil
Prior art keywords
production methods
methylpyrrolidine
making
novel
pyrrolidone production
Prior art date
Application number
BRPI0210460-1A
Other languages
English (en)
Inventor
Todd Werpy
John G Frye Jr
Yong Wang
Alan H Zacher
Original Assignee
Battelle Memorial Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute filed Critical Battelle Memorial Institute
Publication of BR0210460A publication Critical patent/BR0210460A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D201/00—Preparation, separation, purification or stabilisation of unsubstituted lactams
    • C07D201/02—Preparation of lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D201/00—Preparation, separation, purification or stabilisation of unsubstituted lactams
    • C07D201/02—Preparation of lactams
    • C07D201/08—Preparation of lactams from carboxylic acids or derivatives thereof, e.g. hydroxy carboxylic acids, lactones or nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Pyrrole Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

"MéTODOS DE PRODUçãO DE PIRROLIDONAS". A presente invenção proporciona métodos para a produção de N-metil pirrolidina e compostos análogos por meio de hidrogenação. São descritos também catalisadores para esse processo, e são descritos também condições/rendimentos. Outras melhorias de processo podem incluir etapas de extração e de hidrólise. Algumas reações preferidas ocorrem em fase aquosa. Os materiais iniciadores para a produção de N-metil pirrolidina podem incluir ácido succínico, N-metil succinimida, e seus análogos.
BRPI0210460-1A 2001-06-18 2002-06-17 métodos de produção de pirrolidonas BR0210460A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/884,602 US6603021B2 (en) 2001-06-18 2001-06-18 Methods of making pyrrolidones
PCT/US2002/019372 WO2002102772A1 (en) 2001-06-18 2002-06-17 Methods of making pyrrolidones

Publications (1)

Publication Number Publication Date
BR0210460A true BR0210460A (pt) 2006-10-10

Family

ID=25384979

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0210460-1A BR0210460A (pt) 2001-06-18 2002-06-17 métodos de produção de pirrolidonas

Country Status (8)

Country Link
US (4) US6603021B2 (pt)
EP (4) EP1412329B1 (pt)
KR (1) KR100932250B1 (pt)
AT (1) ATE475646T1 (pt)
BR (1) BR0210460A (pt)
DE (1) DE60237157D1 (pt)
MX (1) MXPA03011663A (pt)
WO (1) WO2002102772A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1115389C (zh) * 2000-10-08 2003-07-23 南京化工大学 石油加氢过程催化活性促进剂
US7199250B2 (en) * 2002-12-20 2007-04-03 Battelle Memorial Institute Process for producing cyclic compounds
EP2266957A1 (en) * 2002-12-20 2010-12-29 Battelle Memorial Institute Process for producing an N-alkyl cyclic imide
GB0325384D0 (en) * 2003-10-30 2003-12-03 Davy Process Techn Ltd Process
KR100565474B1 (ko) * 2004-02-18 2006-03-30 씨엠에스테크놀로지(주) Ｎ-메틸-2-피롤리돈의 제조방법
ES2396139T3 (es) * 2004-12-21 2013-02-19 Basf Se Método para la producción de pirrolidonas a partir de succinatos de caldos de fermentación
US7955479B2 (en) * 2006-03-07 2011-06-07 Cem Corporation Method and apparatus for conducting microwave assisted organic reactions with gas-phase reactants
US20080299624A1 (en) * 2007-06-01 2008-12-04 Edward Heslop Continuous fermentation apparatus and method
WO2010063617A1 (de) 2008-12-04 2010-06-10 Basf Se Mischungen aus itaconsäure oder itaconsäurederivaten und primären aminen zur herstellung von 1,3- und 1,4-alkylmethylpyrrolidonen
US8937202B2 (en) * 2010-02-23 2015-01-20 Battelle Memorial Institute Processes and systems for the production of propylene glycol from glycerol
US20110207972A1 (en) * 2010-02-23 2011-08-25 Battelle Memorial Institute Catalysts and processes for the hydrogenolysis of glycerol and other organic compounds for producing polyols and propylene glycol
JP2013528605A (ja) * 2010-05-19 2013-07-11 ビオアンブ，ソシエテ パ アクシオンス シンプリフィエ ピロリドン類の製造方法
BR112012029415A2 (pt) 2010-05-19 2016-08-16 Bioamber Sas processos para a produção de pirrolidonas
TR201904063T4 (tr) * 2011-07-21 2019-04-22 Archer Daniels Midland Co C4 diasitlerin amonyum tuzlarının fermantasyon ile hazırlanması yöntemleri ve bunların C4 türevlerinin hazırlanmasına yönelik entegre yöntemler.
WO2013033649A1 (en) * 2011-09-01 2013-03-07 Myriant Corporation Method for conversion of diammonim succinate in fermentation broth to 2-pyrrolidone and n-methylpyrrolidone
US20130150591A1 (en) * 2011-12-07 2013-06-13 Rolf Pinkos Method for purifying n-alkyl-substituted pyrrolidones by hydrogenation
FR2989971B1 (fr) * 2012-04-27 2016-01-15 Rhodia Operations Procede de preparation de lactames
KR102096542B1 (ko) 2014-02-03 2020-04-02 바텔리 메모리얼 인스티튜트 2,3-부탄다이올의 부타다이엔으로의 전환

Family Cites Families (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2674602A (en) 1954-04-06 Production of n-alkyl lactams
US2187745A (en) * 1934-09-01 1940-01-23 Du Pont Process for hydrogenating amides and imides to amines
US2267757A (en) 1938-07-20 1941-12-30 Gen Aniline & Film Corp Process of producing substituted alpha-pyrrolidones
US3109005A (en) 1961-05-15 1963-10-29 Halcon International Inc Process for making 2-pyrrolidone from maleic anhydride
US3080377A (en) 1961-07-17 1963-03-05 Fmc Corp Preparation of 2-pyrrolidone from succinic anhydride, ammonia and hydrogen in the presence of raney cobalt
US3092638A (en) 1961-07-17 1963-06-04 Fmc Corp Synthesis of 2-pyrrolidone
NL284786A (pt) 1961-10-28 1900-01-01
FR1439192A (fr) 1965-04-07 1966-05-20 Rhone Poulenc Sa Procédé de préparation d'alpha-pyrrolidones nu-substituées
US3637743A (en) 1968-08-28 1972-01-25 Atlantic Richfield Co Production of 2-pyrrolidones
FR2048383A5 (en) 1969-06-25 1971-03-19 Leuna Werke Veb N-alkyllactams prodn
US3634346A (en) 1969-08-15 1972-01-11 Union Carbide Corp Oxidation of cyclic amines to lactams
US3661894A (en) 1970-06-29 1972-05-09 Leuna Werke Veb Method of producing n-alkyl lactams
US3681387A (en) 1970-10-16 1972-08-01 Sun Oil Co Preparation of 2-pyrrolidinone
JPS4926622B1 (pt) 1970-12-30 1974-07-10
US3775431A (en) 1970-12-30 1973-11-27 Mobil Oil Corp Pyrrolidones from ypsilon-butyrolactones using a zeolite catalyst
US3884936A (en) 1971-01-21 1975-05-20 Sun Research Development Preparation of 2-pyrrolidone
JPS49259A (pt) 1972-04-18 1974-01-05
JPS4920586A (pt) 1972-06-19 1974-02-23
JPS5212348B2 (pt) 1972-06-20 1977-04-06
JPS524704B2 (pt) 1972-06-22 1977-02-05
US3812148A (en) 1972-07-21 1974-05-21 Sun Research Development Preparation of 2-pyrrolidone
JPS5119385B2 (pt) 1972-09-09 1976-06-17
JPS5116657A (en) 1974-08-01 1976-02-10 Asahi Chemical Ind Nn arukirurakutamuno seizoho
NL7412694A (nl) 1974-09-26 1976-03-30 Stamicarbon Werkwijze voor de bereiding van een pyrrolidon- -2.
JPS5142107A (ja) 1974-10-07 1976-04-09 Yasushi Aoki Rootaanoheikoidootomonaurootarii pisuton mizuagehonpu
US3966763A (en) 1975-06-30 1976-06-29 Standard Oil Company Process for producing 2-pyrrolidone
SU619484A1 (ru) 1976-02-16 1978-08-15 Институт электрохимии АН СССР Способ получени -метил -2пирролидона
CS191496B1 (en) 1976-06-11 1979-07-31 Jaroslav Palecek Process for preparing n-substituted lactames
US4113735A (en) 1976-12-13 1978-09-12 Chevron Research Company Process for the production of N-acetyl-2-pyrrolidone
NL7704179A (nl) 1977-04-18 1978-10-20 Stamicarbon Werkwijze voor de bereiding van n-gesubstitu- eerde 2-pyrrolidonen.
US4356124A (en) 1979-10-05 1982-10-26 The Standard Oil Company Process for the production of pyrrolidones
US4263175A (en) 1979-10-05 1981-04-21 Standard Oil Company Catalyst for the production of pyrrolidone
NL8002019A (nl) 1980-04-04 1981-11-02 Stamicarbon Werkwijze voor de bereiding van n-alkyl-2-pyrrolidonen.
CS212181B1 (en) 1980-09-23 1982-02-26 Milan Polievka Method of making the n-alkyl-2-pyrolidone
US4420620A (en) 1981-11-27 1983-12-13 National Distillers And Chemical Corporation Preparation of 2-pyrrolidones
US4904804A (en) 1984-07-16 1990-02-27 Phillips Petroleum Company Preparation of 2-pyrrolidone
US4800227A (en) * 1984-08-20 1989-01-24 Phillips Petroleum Company Process for the production of lactams
JPS62120360A (ja) 1985-11-20 1987-06-01 Mitsubishi Chem Ind Ltd Ｎ−アルキルラクタムの製造方法
JPH07116139B2 (ja) * 1986-06-09 1995-12-13 三菱化学株式会社 ラクタム類の製造方法
US4731454A (en) 1986-06-09 1988-03-15 Mitsubishi Chemical Industries Limited Process for producing lactams
DE3622759A1 (de) 1986-07-07 1988-01-28 Huels Chemische Werke Ag Verfahren zur herstellung von c(pfeil abwaerts)1(pfeil abwaerts)- bis c(pfeil abwaerts)6(pfeil abwaerts)-n-alkylpyrrolidonen aus bernsteinsaeureanhydrid bzw. c(pfeil abwaerts)1(pfeil abwaerts)- bis c(pfeil abwaerts)6(pfeil abwaerts)-n-alkylsuccinimid
JPH07116140B2 (ja) 1986-07-21 1995-12-13 三菱化学株式会社 ラクタム類の製造法
DE3701297A1 (de) 1987-01-17 1988-07-28 Basf Ag Verfahren zur herstellung von pyrrolidon bzw. n-methylpyrrolidon
US4841069A (en) 1987-03-30 1989-06-20 Amoco Corporation Ammonolysis-alkylation reactions using ammonia and an alcohol to prepare N-alkyl maleimides and N-alkyl succinimides
US4814464A (en) 1987-03-30 1989-03-21 Amoco Corporation Process for making N-alkylpyrrolidones
US4851546A (en) 1987-10-01 1989-07-25 The Standard Oil Company Preparation of pyrrolidones by catalytic hydrogenation of maleimides
RO96953B1 (ro) 1987-11-16 1989-05-31 Combinatul Ppetrochimic Procedeu de obtinere a n-metilpirolidonei
JPH0678304B2 (ja) 1988-01-21 1994-10-05 三菱化成株式会社 Ｎ−アルキル置換ラクタムの製造方法
JPH0710835B2 (ja) 1988-01-21 1995-02-08 三菱化学株式会社 Ｎ−アルキル置換ラクタムの製造方法
JPH0678305B2 (ja) 1988-01-21 1994-10-05 三菱化成株式会社 Ｎ−メチル−２−ピロリドンの製造方法
SU1558903A1 (ru) 1988-07-01 1990-04-23 Ленинградское научно-производственное объединение по разработке и внедрению нефтехимических процессов "Леннефтехим" Способ получени N-метилпирролидона
US4885371A (en) 1989-06-22 1989-12-05 Gaf Chemicals Corporation Process for the preparation of purified N-alkyl lactams
US5106730A (en) 1989-07-24 1992-04-21 Microprobe Corporation Lactam-containing compositions and methods useful for the hybridization of nucleic acids
JPH0381261A (ja) 1989-08-23 1991-04-05 Idemitsu Kosan Co Ltd ラクタム類の製造方法
EP0422366B1 (de) 1989-09-01 1997-01-22 BASF Aktiengesellschaft Verfahren zur Herstellung N-substituierter Pyrrolidin-2-one
SU1735283A1 (ru) 1989-12-12 1992-05-23 Новочеркасский завод синтетических продуктов Способ получени N-метилпирролидона
SU1735284A1 (ru) 1989-12-12 1992-05-23 Новочеркасский завод синтетических продуктов Способ выделени N-метилпирролидона из побочных продуктов
US5347021A (en) 1990-04-16 1994-09-13 Isp Investments Inc. Process of vapor phase catalytic hydrogenation of maleic anhydride to gamma-butyrolactone in high conversion and high selectivity using an activated catalyst
DE4018243A1 (de) 1990-06-07 1991-12-12 Basf Ag Verfahren zur herstellung von n-substituierten pyrrolidonen
DE4018242A1 (de) 1990-06-07 1991-12-12 Basf Ag Verfahren zur herstellung von n-substituierten pyrrolidonen
JP2868864B2 (ja) 1990-08-09 1999-03-10 イビデン株式会社 プリント配線基板の検査装置
DE4125457A1 (de) 1991-08-01 1993-02-04 Bayer Ag Verfahren zur herstellung von n-substituierten lactamen
DE4139607A1 (de) 1991-11-30 1993-06-03 Basf Ag Verfahren zur herstellung von n-substituierten lactamen
DE4203527A1 (de) 1992-02-07 1993-08-12 Akzo Nv Verfahren zur herstellung von pyrrolidon und n-alkylpyrrolidonen
DE4303334A1 (de) 1993-02-05 1994-08-11 Basf Ag Verfahren zur Herstellung von N-substituierten Pyrrolid-2-onen
DE4321843A1 (de) 1993-07-01 1995-01-12 Basf Ag Verfahren zur Herstellung von Stickstoff-Fünfringheterocyclen
DE4326692A1 (de) 1993-08-10 1995-02-16 Akzo Nobel Nv Verfahren zur Herstellung von gamma-Butyrolacton
CN1043758C (zh) 1993-12-27 1999-06-23 化学工业部北京化工研究院 改进的N－甲基吡咯烷酮及α－吡咯烷酮的生产方法
DE4400407C1 (de) 1994-01-05 1995-05-04 Dichter Hans Joachim Vorrichtung zum Verformen von Glasrohren
US5401856A (en) 1994-02-28 1995-03-28 Arco Chemical Technology, L.P. Process for making pyrrolidones
DE4423603C2 (de) 1994-07-06 2002-01-17 Degussa Verfahren zur Herstellung von N-Alkyl-Lactamen
DE19520258A1 (de) 1995-06-02 1996-12-05 Bayer Ag Verfahren zur Herstellung von 2-Pyrrolidonen
RO111189B1 (ro) 1995-08-07 1996-07-30 Sc Chimcomplex Sa Borzesti One Procedeu de preparare a n-metilpirolidonei
TW341568B (en) 1995-12-27 1998-10-01 Akzo Nobel Nv Process for manufacturing Gamma-butyrolactone and its use
JPH09241220A (ja) 1996-03-05 1997-09-16 Nippon Shokubai Co Ltd ３級アミン化合物の製造法
DE19626123A1 (de) 1996-06-28 1998-01-08 Basf Ag Verfahren zur Herstellung von Pyrrolidonen
CN1054843C (zh) 1996-08-12 2000-07-26 中国石油化工总公司 N－甲基吡咯烷酮的制备方法
JPH10158238A (ja) 1996-12-02 1998-06-16 Tonen Chem Corp Ｎ−メチル−２− ピロリドンの製造方法
RO113640B1 (ro) 1997-09-05 1998-09-30 Sc Chimcomplex Sa Borzesti Procedeu de sinteza a n-metilpirolidonei
BE1012013A6 (fr) 1998-04-09 2000-04-06 Pantochim Sa Procede de production de n-methylpyrrolidone.
JPH11349566A (ja) 1998-06-10 1999-12-21 Tonen Kagaku Kk Ｎ‐メチル‐２‐ピロリドンの回収精製法
JP4036580B2 (ja) 1998-11-24 2008-01-23 三菱化学株式会社 Ｎ−アルキル−２−ピロリドンの製造方法
JP2000256312A (ja) 1999-03-10 2000-09-19 Tonen Chem Corp ピロリドン類の製造法
JP2001002638A (ja) 1999-06-18 2001-01-09 Tonen Chem Corp 高純度ピロリドン類の製造方法
JP2001002640A (ja) 1999-06-18 2001-01-09 Tonen Chem Corp 高純度ピロリドン類の製造方法
JP3996306B2 (ja) 1999-10-14 2007-10-24 三菱化学株式会社 ピロリドン類の製造方法
BE1012946A6 (fr) 1999-10-27 2001-06-05 Pantochim Sa Procede de production de n-methyl pyrrolidone en utilisant de la gamma-butyrolactone et des methylamines mixtes comme materiaux de depart.
DE10004909A1 (de) 2000-02-04 2001-08-09 Basf Ag Verfahren zur Herstellung von N-Methyl-2-pyrrolidon (NMP)
TWI257386B (en) 2000-04-14 2006-07-01 Dairen Chemical Corp Method for preparing lactams
JP2001302626A (ja) 2000-04-21 2001-10-31 Tonen Chem Corp 高純度ピロリドン類の製造方法
JP2001354647A (ja) 2000-06-14 2001-12-25 Mitsubishi Chemicals Corp Ｎ−メチル−２−ピロリドン組成物及びその製造方法
JP2001354646A (ja) 2000-06-14 2001-12-25 Mitsubishi Chemicals Corp ピロリドン組成物及びその製造方法
ATE298743T1 (de) 2000-10-27 2005-07-15 Dairen Chemical Corp Verfahren zur herstellung von lactamen
EP1251122A1 (en) * 2001-04-17 2002-10-23 Dsm N.V. Process for the preparation of epsilon-Caprolactam
EP2266957A1 (en) * 2002-12-20 2010-12-29 Battelle Memorial Institute Process for producing an N-alkyl cyclic imide
ES2396139T3 (es) * 2004-12-21 2013-02-19 Basf Se Método para la producción de pirrolidonas a partir de succinatos de caldos de fermentación

Also Published As

Publication number Publication date
US20030125570A1 (en) 2003-07-03
US20030120087A1 (en) 2003-06-26
WO2002102772B1 (en) 2003-11-20
US20030097006A1 (en) 2003-05-22
WO2002102772A1 (en) 2002-12-27
KR100932250B1 (ko) 2009-12-16
US6632951B2 (en) 2003-10-14
EP1412329A1 (en) 2004-04-28
US20030114687A1 (en) 2003-06-19
ATE475646T1 (de) 2010-08-15
EP2210874A1 (en) 2010-07-28
EP2210877A1 (en) 2010-07-28
US6603021B2 (en) 2003-08-05
US6670483B2 (en) 2003-12-30
US6706893B2 (en) 2004-03-16
EP1412329B1 (en) 2010-07-28
EP2210875A1 (en) 2010-07-28
KR20040012945A (ko) 2004-02-11
DE60237157D1 (de) 2010-09-09
MXPA03011663A (es) 2004-07-08

Similar Documents

Publication Publication Date Title
BR0210460A (pt) métodos de produção de pirrolidonas
IL189359A0 (en) Novel process for the synthesis of 5 - (4 - fluorophenyl) - 1 - [2 - ((2r, 4r)- 4 - hydroxy - 6 - oxo -tetrahydro - pyran - 2 - yl) - ethyl] - 2 - isopropyl- 4 - phenyl - 1h - pyrrole - 3 - carboxylic acid phenylamide
WO2004085349A3 (en) Production of 5-methyl-1-hydrocarbyl-2-pyrrolidone by reductive amination of levulinic acid
WO2003027066A3 (en) Methods of making porphyrins and related compounds with lewis acid
HK1077825A1 (en) process for preparing 5-(4-fluorophenyl)-1-Ä2-(2r,4r)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)ethylÜ-2-isopropyl-4-phenyl-1h-pyrrole-3-carboxylic acid phenylamide
ES2173422T3 (es) Disociacion de treo-metilfenidato.
WO2005048954A3 (en) Continuous process for producing hydroxyazapirones by oxidation
WO2002026705A8 (en) Highly enantiomerically pure lactam-substituted propanoic acid derivatives and their preparation
MY134290A (en) Methods of making pyrrolidones
DE50310200D1 (de) Verfahren zur herstellung von aminoalkoxybenzylaminen und aminoalkoxybenzonitrilen als zwischenprodukte
WO2003078420A3 (en) Process for making chiral 1,4-disubstituted piperazines
WO2000064882A3 (en) Enantiomers of mercapto lactones and processes for their synthesis
RS20050366A (en) A method for preparing indan-1,3- dicarboxylic acid
PT1001929E (pt) Processo para o fabrico de acidos 3-ciano-2,4-di-halogeno-5-fluorobenzoicos
WO2004039819A3 (de) Verfahren zur herstellung von palladium(0)-haltigen verbindungen
IL178228A (en) Process for the semisynthesis of deserpidine
DE50002865D1 (de) Verfahren zur herstellung von benzofuranonoximen
BR0011559A (pt) Processo para a preparação de derivados de 10, 11-metano benzossuberano
MX2007000042A (es) Metodo para producir una forma enantiomerica de derivados de acido 2,3-diaminopropionico.
PT1444244E (pt) Processo para a preparacao de desclaritromicina, assim como produtos intermedios
DE50213160D1 (de) Verfahren zur Herstellung von Pyrrolen
ATE281428T1 (de) Verfahren zur herstellung von methoxyimino- essigsäureamiden
MXPA02012053A (es) Procedimiento para la obtencion de 3,3,5-trimetilciclohexanol.
AU2002254935A1 (en) Use of neuroactive substances and combinations thereof for the treatment of parkinsons disease
ATE354376T1 (de) Zusammensetzungen für die elektroporation

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements