BG64127B1 - Противопаразитни пиразоли - Google Patents

Противопаразитни пиразоли Download PDF

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Publication number
BG64127B1
BG64127B1 BG103454A BG10345499A BG64127B1 BG 64127 B1 BG64127 B1 BG 64127B1 BG 103454 A BG103454 A BG 103454A BG 10345499 A BG10345499 A BG 10345499A BG 64127 B1 BG64127 B1 BG 64127B1
Authority
BG
Bulgaria
Prior art keywords
dichloro
cyano
halo
hydrogen
pyrazole
Prior art date
Application number
BG103454A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG103454A (en
Inventor
Bernard J. Banks
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625290.3A external-priority patent/GB9625290D0/en
Priority claimed from GBGB9702235.4A external-priority patent/GB9702235D0/en
Priority claimed from GBGB9712045.5A external-priority patent/GB9712045D0/en
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of BG103454A publication Critical patent/BG103454A/xx
Publication of BG64127B1 publication Critical patent/BG64127B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BG103454A 1996-12-05 1999-06-01 Противопаразитни пиразоли BG64127B1 (bg)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9625290.3A GB9625290D0 (en) 1996-12-05 1996-12-05 Parasiticidal agents
GBGB9702235.4A GB9702235D0 (en) 1997-02-04 1997-02-04 Parasiticidal agents
GBGB9712045.5A GB9712045D0 (en) 1997-06-10 1997-06-10 Parasiticidal agents
PCT/EP1997/006697 WO1998024767A1 (en) 1996-12-05 1997-11-25 Parasiticidal pyrazoles

Publications (2)

Publication Number Publication Date
BG103454A BG103454A (en) 2000-01-31
BG64127B1 true BG64127B1 (bg) 2004-01-30

Family

ID=27268619

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103454A BG64127B1 (bg) 1996-12-05 1999-06-01 Противопаразитни пиразоли

Country Status (40)

Country Link
US (2) US6075043A (ko)
EP (1) EP0946515B1 (ko)
JP (2) JP3950483B2 (ko)
KR (1) KR100354311B1 (ko)
CN (1) CN1106386C (ko)
AR (1) AR013879A1 (ko)
AT (1) ATE233736T1 (ko)
AU (1) AU720705B2 (ko)
BG (1) BG64127B1 (ko)
BR (1) BR9713565A (ko)
CA (1) CA2273951C (ko)
CO (1) CO5031251A1 (ko)
CZ (1) CZ295295B6 (ko)
DE (1) DE69719547T2 (ko)
DK (1) DK0946515T3 (ko)
DZ (1) DZ2360A1 (ko)
EA (1) EA002278B1 (ko)
ES (1) ES2191870T3 (ko)
HK (1) HK1029111A1 (ko)
HR (1) HRP970663B1 (ko)
HU (1) HUP0000544A3 (ko)
ID (1) ID21556A (ko)
IL (1) IL129866A (ko)
IS (1) IS1982B (ko)
MA (1) MA24414A1 (ko)
MY (1) MY117021A (ko)
NO (2) NO313518B1 (ko)
NZ (1) NZ335611A (ko)
OA (1) OA11055A (ko)
PA (1) PA8442101A1 (ko)
PE (1) PE20199A1 (ko)
PL (1) PL190926B1 (ko)
PT (1) PT946515E (ko)
RS (1) RS49720B (ko)
SK (1) SK285203B6 (ko)
TN (1) TNSN97197A1 (ko)
TW (1) TW524667B (ko)
UA (1) UA60321C2 (ko)
UY (2) UY24798A1 (ko)
WO (1) WO1998024767A1 (ko)

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TW524667B (en) 1996-12-05 2003-03-21 Pfizer Parasiticidal pyrazoles
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GB9811050D0 (en) * 1998-05-22 1998-07-22 Pfizer Ltd Pyrazoles
US6531501B1 (en) 1998-12-11 2003-03-11 Aventis Cropscience, S.A. Control of arthropods in animals
AR021608A1 (es) * 1998-12-11 2002-07-31 Merial Ltd Represion de artropodos en animales
GB9916052D0 (en) * 1999-07-08 1999-09-08 Pfizer Ltd Anthelmintic compositions
BR0015945A (pt) 1999-12-02 2002-11-12 Aventis Cropscience Sa Controle de artrópodos em animais
AU2003218758A1 (en) * 2002-03-14 2003-09-22 Syngenta Participations Ag Derivatives of 1-phenyl-3-phenylpyrazole as herbicides
CH697663B1 (de) * 2003-01-07 2009-01-15 Lanxess Deutschland Gmbh Pyrazolylalkine.
WO2005023773A1 (en) * 2003-09-04 2005-03-17 Pfizer Limited Process for the preparation of substituted aryl pyrazoles
US7514464B2 (en) 2003-12-18 2009-04-07 Pfizer Limited Substituted arylpyrazoles
GB0329314D0 (en) * 2003-12-18 2004-01-21 Pfizer Ltd Substituted arylpyrazoles
AU2005223483B2 (en) 2004-03-18 2009-04-23 Zoetis Llc N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides
US20080146643A1 (en) * 2005-06-15 2008-06-19 Pfizer Limited Combination
US20080176865A1 (en) * 2005-06-15 2008-07-24 Pfizer Limited Substituted arylpyrazoles
AU2006257647A1 (en) * 2005-06-15 2006-12-21 Pfizer Limited Substituted arylpyrazoles for use against parasites
US20070149464A1 (en) * 2005-06-15 2007-06-28 Pfizer Inc. Combination
US7645786B2 (en) 2005-06-15 2010-01-12 Pfizer Inc. Substituted arylpyrazoles
CA2614282A1 (en) 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
EP1783114A1 (en) * 2005-11-03 2007-05-09 Novartis AG N-(hetero)aryl indole derivatives as pesticides
DE102006061537A1 (de) 2006-12-27 2008-07-03 Bayer Healthcare Ag Mittel zur Bekämpfung von Parasiten an Tieren
DE102006061538A1 (de) * 2006-12-27 2008-07-03 Bayer Healthcare Ag Kombinationsprodukt zur Bekämpfung von Parasiten an Tieren
EP2556060A1 (en) 2010-04-08 2013-02-13 Ah Usa 42 Llc Substituted 3,5- diphenyl-isoxazoline derivatives as insecticides and acaricides
MX2013001437A (es) 2010-08-05 2013-06-05 Zoetis Llc Derivados de isoxazolina como agentes antiparasitarios.
WO2012038851A1 (en) 2010-09-24 2012-03-29 Pfizer Inc. Isoxazoline oximes as antiparasitic agents
SI2683723T1 (sl) 2011-03-10 2016-07-29 Zoetis Services Llc Spirociklični izoksazolinski derivati kot antiparazitiki
CN103562190A (zh) 2011-03-22 2014-02-05 佐蒂斯有限责任公司 作为抗寄生虫药的异噁唑啉衍生物
BR112013033914A2 (pt) 2011-06-30 2016-11-22 Hansen Ab Gmbh agente para o controle de parasitas em animais e uso de um agente
JP5997779B2 (ja) 2012-02-03 2016-09-28 ゾエティス・サービシーズ・エルエルシー 抗寄生虫薬としてのジヒドロフランアゼチジン誘導体
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
EP2855457A1 (en) 2012-05-09 2015-04-08 Zoetis Products LLC Azetidine derivatives as antiparasitic agents
MX363173B (es) 2012-12-12 2019-03-12 Zoetis Services Llc Composiciones inyectables de fenilpirazol.
KR102665710B1 (ko) 2017-08-24 2024-05-14 노보 노르디스크 에이/에스 Glp-1 조성물 및 그 용도
CN111116478B (zh) * 2019-12-18 2021-10-26 浙江金伯士药业有限公司 一种兽用抗生素维吉霉素中间体的制备方法
IL294521A (en) 2020-02-18 2022-09-01 Novo Nordisk As glp-1 compounds and their uses
CN115894374A (zh) * 2023-02-16 2023-04-04 广州佳途科技股份有限公司 一种氟甲腈的制备方法及其应用

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DE69627281T2 (de) * 1995-12-19 2003-11-13 Bayer Cropscience S.A., Lyon Neue 1-Aryl Pyrazol Derivate und ihre Verwendung als Schädlingsbekämpfungsmittel
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GR1002899B (el) * 1996-03-29 1998-05-11 Rhone Merieux Περιλαιμιο κατα ψυλλων και κροτωνων για σκυλους και γατες, με βαση ν-φαινυλπυραζολη
IE80657B1 (en) * 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
IE970215A1 (en) * 1996-03-29 1997-10-08 Rhone Merieux Direct pour-on skin solution for antiparasitic use in cattle¹and sheep
TW524667B (en) 1996-12-05 2003-03-21 Pfizer Parasiticidal pyrazoles
US7100379B2 (en) * 2003-08-14 2006-09-05 Samsung Electronics Co., Ltd. Water supply control apparatus and method for ice maker

Also Published As

Publication number Publication date
BR9713565A (pt) 2000-03-14
RS49720B (sr) 2007-12-31
DZ2360A1 (fr) 2002-12-28
IL129866A0 (en) 2000-02-29
HUP0000544A3 (en) 2002-01-28
IS5050A (is) 1999-05-11
CN1106386C (zh) 2003-04-23
UY24923A1 (es) 1998-09-01
IS1982B (is) 2005-01-14
UA60321C2 (uk) 2003-10-15
NO992732L (no) 1999-08-05
PT946515E (pt) 2003-06-30
CZ295295B6 (cs) 2005-06-15
IL129866A (en) 2004-05-12
DE69719547D1 (de) 2003-04-10
EP0946515A1 (en) 1999-10-06
MA24414A1 (fr) 1998-07-01
TNSN97197A1 (fr) 2005-03-15
BG103454A (en) 2000-01-31
CA2273951C (en) 2003-04-01
AU5485998A (en) 1998-06-29
CN1258282A (zh) 2000-06-28
NO992736D0 (no) 1999-06-04
PL190926B1 (pl) 2006-02-28
NZ335611A (en) 2001-01-26
PL333922A1 (en) 2000-01-31
UY24798A1 (es) 2000-09-29
AR013879A1 (es) 2001-01-31
OA11055A (en) 2002-03-07
EA199900447A1 (ru) 2000-02-28
HRP970663A2 (en) 1998-10-31
TW524667B (en) 2003-03-21
WO1998024767A1 (en) 1998-06-11
EP0946515B1 (en) 2003-03-05
HK1029111A1 (en) 2001-03-23
CZ195199A3 (cs) 2000-08-16
AU720705B2 (en) 2000-06-08
SK74099A3 (en) 2001-02-12
DE69719547T2 (de) 2003-10-02
EA002278B1 (ru) 2002-02-28
NO313518B1 (no) 2002-10-14
US6075043A (en) 2000-06-13
HRP970663B1 (en) 2003-10-31
PE20199A1 (es) 1999-03-05
PA8442101A1 (es) 2000-05-24
HUP0000544A2 (hu) 2000-06-28
KR20000057432A (ko) 2000-09-15
DK0946515T3 (da) 2003-07-14
ID21556A (id) 1999-06-24
MY117021A (en) 2004-04-30
SK285203B6 (sk) 2006-08-03
NO992732D0 (no) 1999-06-04
JP2000505812A (ja) 2000-05-16
JP3950483B2 (ja) 2007-08-01
CO5031251A1 (es) 2001-04-27
KR100354311B1 (ko) 2002-09-28
JP2007211016A (ja) 2007-08-23
CA2273951A1 (en) 1998-06-11
ES2191870T3 (es) 2003-09-16
YU25299A (sh) 2002-10-18
US6268509B1 (en) 2001-07-31
ATE233736T1 (de) 2003-03-15

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