AR013879A1 - Compuesto parasiticida derivado pirazol, formulaciones veterinarias o agricolas y composiciones farmaceuticas que lo contienen, el uso de dicho compuesto para la manufactura de medicamentos, compuestos utiles y procedimiento para la fabricacion de dicho compuesto - Google Patents

Compuesto parasiticida derivado pirazol, formulaciones veterinarias o agricolas y composiciones farmaceuticas que lo contienen, el uso de dicho compuesto para la manufactura de medicamentos, compuestos utiles y procedimiento para la fabricacion de dicho compuesto

Info

Publication number
AR013879A1
AR013879A1 ARP970105679A ARP970105679A AR013879A1 AR 013879 A1 AR013879 A1 AR 013879A1 AR P970105679 A ARP970105679 A AR P970105679A AR P970105679 A ARP970105679 A AR P970105679A AR 013879 A1 AR013879 A1 AR 013879A1
Authority
AR
Argentina
Prior art keywords
compound
manufacture
veterinary
hydrogen
pharmaceutical compositions
Prior art date
Application number
ARP970105679A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625290.3A external-priority patent/GB9625290D0/en
Priority claimed from GBGB9702235.4A external-priority patent/GB9702235D0/en
Priority claimed from GBGB9712045.5A external-priority patent/GB9712045D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of AR013879A1 publication Critical patent/AR013879A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)

Abstract

Un compuesto parasiticida derivado pirazol de formula (I) o una de sus sales aceptables desde el punto de vista farmacéutico, veterinario o agrícolao un solvato aceptable desde el punto de vista farmacéutico, veterinario o agrícola decualq uiera de las entidades en la que R1 es fenilo, 2,4,6-trisustituido o piridin-2-ilo 3,5-disustituido; R3 es alquilo C1-4 opcionalmente sustituido con hidroxi o con uno o más halogenos, ciano,acanoílo, C1-5 o fenilo; R5 eshidrogeno, alqui lo C1-4, amino o halogeno; R2 y R4 se seleccionan cada uno independientemente, entre hidrogeno, alquiloC1-4, fluoro, cloro y bromo o, junto al átomo de carbono al que se encuentran unidos, forman un grupo cicloalquilo C3-6;R6 y R8 se selecci onan cada uno,independientemente, entre hidrogeno, alquilo C1-4, fluoro, cloro y bromo; o, cuando R2 y R4 no forman parte de un grupo cicloalquilo, R2 y R6, junto a losátomos de carbono a los que se encuentran unidos, puedenformar un grupo cicloalquilo C5-7; y R7 es hidrogeno, alquilo C1-4 opcionalmente sustituidocon uno o más halogenos o alcoxi. Se describen también formulaciones veterinarias o agrícolas y composiciones farmacéuticas que contienendichocompuesto, el uso de dicho compuesto para la manufactura de medicamentos, compuestos utiles y procedimiento para la fabricacion de dicho compuesto.
ARP970105679A 1996-12-05 1997-12-03 Compuesto parasiticida derivado pirazol, formulaciones veterinarias o agricolas y composiciones farmaceuticas que lo contienen, el uso de dicho compuesto para la manufactura de medicamentos, compuestos utiles y procedimiento para la fabricacion de dicho compuesto AR013879A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9625290.3A GB9625290D0 (en) 1996-12-05 1996-12-05 Parasiticidal agents
GBGB9702235.4A GB9702235D0 (en) 1997-02-04 1997-02-04 Parasiticidal agents
GBGB9712045.5A GB9712045D0 (en) 1997-06-10 1997-06-10 Parasiticidal agents

Publications (1)

Publication Number Publication Date
AR013879A1 true AR013879A1 (es) 2001-01-31

Family

ID=27268619

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970105679A AR013879A1 (es) 1996-12-05 1997-12-03 Compuesto parasiticida derivado pirazol, formulaciones veterinarias o agricolas y composiciones farmaceuticas que lo contienen, el uso de dicho compuesto para la manufactura de medicamentos, compuestos utiles y procedimiento para la fabricacion de dicho compuesto

Country Status (40)

Country Link
US (2) US6075043A (es)
EP (1) EP0946515B1 (es)
JP (2) JP3950483B2 (es)
KR (1) KR100354311B1 (es)
CN (1) CN1106386C (es)
AR (1) AR013879A1 (es)
AT (1) ATE233736T1 (es)
AU (1) AU720705B2 (es)
BG (1) BG64127B1 (es)
BR (1) BR9713565A (es)
CA (1) CA2273951C (es)
CO (1) CO5031251A1 (es)
CZ (1) CZ295295B6 (es)
DE (1) DE69719547T2 (es)
DK (1) DK0946515T3 (es)
DZ (1) DZ2360A1 (es)
EA (1) EA002278B1 (es)
ES (1) ES2191870T3 (es)
HK (1) HK1029111A1 (es)
HR (1) HRP970663B1 (es)
HU (1) HUP0000544A3 (es)
ID (1) ID21556A (es)
IL (1) IL129866A (es)
IS (1) IS1982B (es)
MA (1) MA24414A1 (es)
MY (1) MY117021A (es)
NO (2) NO992736D0 (es)
NZ (1) NZ335611A (es)
OA (1) OA11055A (es)
PA (1) PA8442101A1 (es)
PE (1) PE20199A1 (es)
PL (1) PL190926B1 (es)
PT (1) PT946515E (es)
RS (1) RS49720B (es)
SK (1) SK285203B6 (es)
TN (1) TNSN97197A1 (es)
TW (1) TW524667B (es)
UA (1) UA60321C2 (es)
UY (2) UY24798A1 (es)
WO (1) WO1998024767A1 (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW524667B (en) 1996-12-05 2003-03-21 Pfizer Parasiticidal pyrazoles
GB9801851D0 (en) * 1998-01-29 1998-03-25 Pfizer Ltd Parasiticidal agents
GB9811050D0 (en) * 1998-05-22 1998-07-22 Pfizer Ltd Pyrazoles
US6531501B1 (en) 1998-12-11 2003-03-11 Aventis Cropscience, S.A. Control of arthropods in animals
AR021608A1 (es) * 1998-12-11 2002-07-31 Merial Ltd Represion de artropodos en animales
GB9916052D0 (en) * 1999-07-08 1999-09-08 Pfizer Ltd Anthelmintic compositions
MY129771A (en) 1999-12-02 2007-04-30 Merial Ltd Control of arthropods in animals
AU2003218758A1 (en) * 2002-03-14 2003-09-22 Syngenta Participations Ag Derivatives of 1-phenyl-3-phenylpyrazole as herbicides
CH697663B1 (de) * 2003-01-07 2009-01-15 Lanxess Deutschland Gmbh Pyrazolylalkine.
WO2005023773A1 (en) * 2003-09-04 2005-03-17 Pfizer Limited Process for the preparation of substituted aryl pyrazoles
GB0329314D0 (en) * 2003-12-18 2004-01-21 Pfizer Ltd Substituted arylpyrazoles
US7514464B2 (en) * 2003-12-18 2009-04-07 Pfizer Limited Substituted arylpyrazoles
EP1735284A1 (en) 2004-03-18 2006-12-27 Pfizer Limited N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides
US20080146643A1 (en) * 2005-06-15 2008-06-19 Pfizer Limited Combination
US20070149464A1 (en) * 2005-06-15 2007-06-28 Pfizer Inc. Combination
US20080176865A1 (en) * 2005-06-15 2008-07-24 Pfizer Limited Substituted arylpyrazoles
MX2007015114A (es) * 2005-06-15 2008-02-15 Pfizer Ltd Arilpirazoles sustituidos.
US7645786B2 (en) 2005-06-15 2010-01-12 Pfizer Inc. Substituted arylpyrazoles
WO2007006003A2 (en) 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
EP1783114A1 (en) * 2005-11-03 2007-05-09 Novartis AG N-(hetero)aryl indole derivatives as pesticides
DE102006061538A1 (de) * 2006-12-27 2008-07-03 Bayer Healthcare Ag Kombinationsprodukt zur Bekämpfung von Parasiten an Tieren
DE102006061537A1 (de) * 2006-12-27 2008-07-03 Bayer Healthcare Ag Mittel zur Bekämpfung von Parasiten an Tieren
JP2013523805A (ja) 2010-04-08 2013-06-17 ゾエティス・エルエルシー 殺虫剤および殺ダニ剤としての置換3,5−ジフェニル−イソオキサゾリン誘導体
NZ606194A (en) 2010-08-05 2013-12-20 Zoetis Services Llc Isoxazoline derivatives as antiparasitic agents
WO2012038851A1 (en) 2010-09-24 2012-03-29 Pfizer Inc. Isoxazoline oximes as antiparasitic agents
PT2683723T (pt) 2011-03-10 2016-08-05 Zoetis Services Llc Derivados espirocíclicos de isoxazolina como agentes antiparasitários
WO2012127347A1 (en) 2011-03-22 2012-09-27 Pfizer Inc. Isoxazoline derivatives as antiparasitic agents
WO2013000572A1 (de) 2011-06-30 2013-01-03 2LUTION GmbH Mittel zur bekämpfung von parasiten an tieren
RU2014131951A (ru) 2012-02-03 2016-03-27 Зоэтис Ллс Производные дигидрофуран азетидина в качестве противопаразитарных агентов
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
BR112014027805A2 (pt) 2012-05-09 2017-06-27 Zoetis Llc derivados de azetidina como agentes antiparasitários
BR112015013491B1 (pt) 2012-12-12 2021-03-30 Zoetis Services Llc Composição veterinária ectoparasítica injetável e uso da mesma
PL3474820T3 (pl) 2017-08-24 2024-05-13 Novo Nordisk A/S Kompozycje glp-1 i ich zastosowania
CN111116478B (zh) * 2019-12-18 2021-10-26 浙江金伯士药业有限公司 一种兽用抗生素维吉霉素中间体的制备方法
KR20220143037A (ko) 2020-02-18 2022-10-24 노보 노르디스크 에이/에스 Glp-1 조성물 및 이의 용도
CN115894374A (zh) * 2023-02-16 2023-04-04 广州佳途科技股份有限公司 一种氟甲腈的制备方法及其应用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658725A1 (de) * 1976-12-24 1978-07-06 Bayer Ag Mittel zur bekaempfung von tierischen ektoparasiten mit stark ausgepraegter residualwirkung
US4479968A (en) * 1980-10-17 1984-10-30 The Wellcome Foundation Ltd. Control of ectoparasitic infestations of pigs
GB2086302A (en) * 1980-10-24 1982-05-12 Bone Cravens Ltd Prefill Valve System
GB8713768D0 (en) * 1987-06-12 1987-07-15 May & Baker Ltd Compositions of matter
GB8531485D0 (en) * 1985-12-20 1986-02-05 May & Baker Ltd Compositions of matter
US5547974A (en) * 1985-12-20 1996-08-20 Rhone-Poulenc Agriculture Ltd. Derivatives of N-phenylpyrazoles
GB8713769D0 (en) * 1987-06-12 1987-07-15 May & Baker Ltd Compositions of matter
US5232940A (en) * 1985-12-20 1993-08-03 Hatton Leslie R Derivatives of N-phenylpyrazoles
GB8613914D0 (en) * 1986-06-07 1986-07-09 Coopers Animal Health Liquid formulations
ATE65013T1 (de) * 1986-12-05 1991-07-15 Ciba Geigy Ag Ektoparasitizide nicht-waessrige pour-onfl¨ssigformulierung.
DE3706993A1 (de) * 1987-03-05 1988-09-15 Bayer Ag 5-amino-3-halogenalkyl-1-aryl-pyrazole
SE455750B (sv) 1987-06-11 1988-08-01 Ericsson Telefon Ab L M Digitalt tidsmultiplext mobiltelefonisystem med ett effektivt utnyttjande av varje tidsram
GB9120641D0 (en) * 1991-09-27 1991-11-06 Ici Plc Heterocyclic compounds
ZA94170B (en) * 1993-01-20 1995-03-15 Soltec Res Pty Ltd Ectoparasiticidal formulation
AUPM437194A0 (en) * 1994-03-11 1994-03-31 Commonwealth Scientific And Industrial Research Organisation Pesticide formulation
GB9601128D0 (en) * 1995-08-11 1996-03-20 Pfizer Ltd Parasiticidal compounds
DE69632538T2 (de) 1995-08-11 2005-05-19 Novozymes A/S Neuartige lipolytische enzyme
JPH0987111A (ja) * 1995-09-27 1997-03-31 Sumitomo Chem Co Ltd 害虫駆除用毒餌剤
FR2739255B1 (fr) * 1995-09-29 1998-09-04 Rhone Merieux Composition antiparasitaire pour le traitement et la protection des animaux de compagnie
EP0780378B1 (en) * 1995-12-19 2003-04-09 Bayer CropScience S.A. New 1-aryl pyrazole derivatives and their use as pesticides
IE80657B1 (en) * 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
GR970100096A (el) * 1996-03-29 1997-11-28 Merial Εξωτερικη διαταξη κατα των παρασιτων για βοοειδη με βαση τη ν-φαινυλπυραζολη, ειδικα σκουλαρικια.
GR1002899B (el) * 1996-03-29 1998-05-11 Rhone Merieux Περιλαιμιο κατα ψυλλων και κροτωνων για σκυλους και γατες, με βαση ν-φαινυλπυραζολη
IE970215A1 (en) * 1996-03-29 1997-10-08 Rhone Merieux Direct pour-on skin solution for antiparasitic use in cattle¹and sheep
TW524667B (en) 1996-12-05 2003-03-21 Pfizer Parasiticidal pyrazoles
US7100379B2 (en) * 2003-08-14 2006-09-05 Samsung Electronics Co., Ltd. Water supply control apparatus and method for ice maker

Also Published As

Publication number Publication date
PT946515E (pt) 2003-06-30
EP0946515A1 (en) 1999-10-06
YU25299A (sh) 2002-10-18
PE20199A1 (es) 1999-03-05
IS5050A (is) 1999-05-11
BR9713565A (pt) 2000-03-14
EA002278B1 (ru) 2002-02-28
MA24414A1 (fr) 1998-07-01
UY24798A1 (es) 2000-09-29
AU720705B2 (en) 2000-06-08
NO992736D0 (no) 1999-06-04
CN1258282A (zh) 2000-06-28
PL190926B1 (pl) 2006-02-28
IL129866A (en) 2004-05-12
HK1029111A1 (en) 2001-03-23
KR20000057432A (ko) 2000-09-15
PL333922A1 (en) 2000-01-31
JP3950483B2 (ja) 2007-08-01
HUP0000544A2 (hu) 2000-06-28
DK0946515T3 (da) 2003-07-14
HUP0000544A3 (en) 2002-01-28
KR100354311B1 (ko) 2002-09-28
US6075043A (en) 2000-06-13
CN1106386C (zh) 2003-04-23
WO1998024767A1 (en) 1998-06-11
NO992732L (no) 1999-08-05
ES2191870T3 (es) 2003-09-16
DE69719547D1 (de) 2003-04-10
CO5031251A1 (es) 2001-04-27
BG103454A (en) 2000-01-31
US6268509B1 (en) 2001-07-31
UY24923A1 (es) 1998-09-01
CZ195199A3 (cs) 2000-08-16
IL129866A0 (en) 2000-02-29
CA2273951A1 (en) 1998-06-11
CA2273951C (en) 2003-04-01
ID21556A (id) 1999-06-24
DE69719547T2 (de) 2003-10-02
EA199900447A1 (ru) 2000-02-28
BG64127B1 (bg) 2004-01-30
TW524667B (en) 2003-03-21
JP2007211016A (ja) 2007-08-23
TNSN97197A1 (fr) 2005-03-15
JP2000505812A (ja) 2000-05-16
PA8442101A1 (es) 2000-05-24
DZ2360A1 (fr) 2002-12-28
EP0946515B1 (en) 2003-03-05
HRP970663A2 (en) 1998-10-31
NZ335611A (en) 2001-01-26
CZ295295B6 (cs) 2005-06-15
NO992732D0 (no) 1999-06-04
SK285203B6 (sk) 2006-08-03
RS49720B (sr) 2007-12-31
MY117021A (en) 2004-04-30
HRP970663B1 (en) 2003-10-31
NO313518B1 (no) 2002-10-14
IS1982B (is) 2005-01-14
OA11055A (en) 2002-03-07
UA60321C2 (uk) 2003-10-15
AU5485998A (en) 1998-06-29
SK74099A3 (en) 2001-02-12
ATE233736T1 (de) 2003-03-15

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