YU25299A - Paraziticidni pirazoli - Google Patents

Paraziticidni pirazoli

Info

Publication number
YU25299A
YU25299A YU25299A YU25299A YU25299A YU 25299 A YU25299 A YU 25299A YU 25299 A YU25299 A YU 25299A YU 25299 A YU25299 A YU 25299A YU 25299 A YU25299 A YU 25299A
Authority
YU
Yugoslavia
Prior art keywords
hydrogen
alkyl
halo
cycloalkyl group
veterinarily
Prior art date
Application number
YU25299A
Other languages
English (en)
Inventor
Bernard Joseph Banks
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625290.3A external-priority patent/GB9625290D0/en
Priority claimed from GBGB9702235.4A external-priority patent/GB9702235D0/en
Priority claimed from GBGB9712045.5A external-priority patent/GB9712045D0/en
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of YU25299A publication Critical patent/YU25299A/sh
Publication of RS49720B publication Critical patent/RS49720B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)

Abstract

Jedinjenja formule (I) ili njihove farmaceutski, veterinarski ili poljoprivredno prihvatljive soli, ili farmaceutski, veterinarski ili poljoprivredno prihvatljivi solvati bilo kog entiteta, pri cemu R1 je 2,4,6-trisupstituisani fenil ili 3,5-disupstituisani piridin-2-il; R3 je C1-C4 alkil proizvoljno supstituisan sa hidroksi ili sa jednim ili vise halogena; cijano, C1 do C5 alkanoil ili fenil; R5 je vodonik, C1 do C4 alkil, amino ili halogen; R2 i R4 su svaki nezavisno izabrani od vodonika, C1 do C4 alkil, fluor, hlor ili brom ili, zajedno sa ugljenikovim atomom za koji su pricvrsceni, formira C3 do C6 a cikloalkil grupu; R6 i R8 su svaki nezavisno izabrani od vodonika, C1 do C4 alkil, fluor, hlor ili brom; ili, kada R2 i R4 ne formiraju deo cikloalkil grupe, R2 i R6 zajedno sa ugljenikovim atomom za koji su pricvrsceni, mogu graditi C5 do C7 cikloalkil grupu; i R7 je vodonik, C1 do C4 alkil proizvoljno supstituisani sa jednim ili vise halogena, ili C1 do C4 alkoksi; paraziticidni su agensi.
YUP-252/99A 1996-12-05 1997-11-25 Paraziticidni pirazoli RS49720B (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9625290.3A GB9625290D0 (en) 1996-12-05 1996-12-05 Parasiticidal agents
GBGB9702235.4A GB9702235D0 (en) 1997-02-04 1997-02-04 Parasiticidal agents
GBGB9712045.5A GB9712045D0 (en) 1997-06-10 1997-06-10 Parasiticidal agents

Publications (2)

Publication Number Publication Date
YU25299A true YU25299A (sh) 2002-10-18
RS49720B RS49720B (sr) 2007-12-31

Family

ID=27268619

Country Status (40)

Country Link
US (2) US6075043A (sh)
EP (1) EP0946515B1 (sh)
JP (2) JP3950483B2 (sh)
KR (1) KR100354311B1 (sh)
CN (1) CN1106386C (sh)
AR (1) AR013879A1 (sh)
AT (1) ATE233736T1 (sh)
AU (1) AU720705B2 (sh)
BG (1) BG64127B1 (sh)
BR (1) BR9713565A (sh)
CA (1) CA2273951C (sh)
CO (1) CO5031251A1 (sh)
CZ (1) CZ295295B6 (sh)
DE (1) DE69719547T2 (sh)
DK (1) DK0946515T3 (sh)
DZ (1) DZ2360A1 (sh)
EA (1) EA002278B1 (sh)
ES (1) ES2191870T3 (sh)
HK (1) HK1029111A1 (sh)
HR (1) HRP970663B1 (sh)
HU (1) HUP0000544A3 (sh)
ID (1) ID21556A (sh)
IL (1) IL129866A (sh)
IS (1) IS1982B (sh)
MA (1) MA24414A1 (sh)
MY (1) MY117021A (sh)
NO (2) NO313518B1 (sh)
NZ (1) NZ335611A (sh)
OA (1) OA11055A (sh)
PA (1) PA8442101A1 (sh)
PE (1) PE20199A1 (sh)
PL (1) PL190926B1 (sh)
PT (1) PT946515E (sh)
RS (1) RS49720B (sh)
SK (1) SK285203B6 (sh)
TN (1) TNSN97197A1 (sh)
TW (1) TW524667B (sh)
UA (1) UA60321C2 (sh)
UY (2) UY24798A1 (sh)
WO (1) WO1998024767A1 (sh)

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BR112013006686A2 (pt) 2010-09-24 2017-11-14 Zoetis Llc isoxazolina oximas como agentes antiparasitários
WO2012120399A1 (en) 2011-03-10 2012-09-13 Pfizer Inc. Spirocyclic isoxazoline derivatives as antiparasitic agents
AU2012232748A1 (en) 2011-03-22 2013-09-12 Zoetis Services Llc Isoxazoline derivatives as antiparasitic agents
CA2840704A1 (en) 2011-06-30 2013-01-03 Hansen-Ab Gmbh Agents for the control of parasites on animals
EP2814825B1 (en) 2012-02-03 2016-03-23 Zoetis Services LLC Dihydrofuran azetidine derivatives as antiparasitic agents
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
BR112014027805A2 (pt) 2012-05-09 2017-06-27 Zoetis Llc derivados de azetidina como agentes antiparasitários
WO2014093481A1 (en) 2012-12-12 2014-06-19 Zoetis Llc Phenylpyrazole injectable compositions
WO2019038412A1 (en) 2017-08-24 2019-02-28 Novo Nordisk A/S GLP-1 COMPOSITIONS AND USES THEREOF
CN111116478B (zh) * 2019-12-18 2021-10-26 浙江金伯士药业有限公司 一种兽用抗生素维吉霉素中间体的制备方法
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CN115894374A (zh) * 2023-02-16 2023-04-04 广州佳途科技股份有限公司 一种氟甲腈的制备方法及其应用

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Also Published As

Publication number Publication date
BG64127B1 (bg) 2004-01-30
ID21556A (id) 1999-06-24
PA8442101A1 (es) 2000-05-24
DK0946515T3 (da) 2003-07-14
US6075043A (en) 2000-06-13
JP2007211016A (ja) 2007-08-23
PL333922A1 (en) 2000-01-31
WO1998024767A1 (en) 1998-06-11
PE20199A1 (es) 1999-03-05
UY24923A1 (es) 1998-09-01
NZ335611A (en) 2001-01-26
HK1029111A1 (en) 2001-03-23
ATE233736T1 (de) 2003-03-15
AU720705B2 (en) 2000-06-08
DE69719547D1 (de) 2003-04-10
UY24798A1 (es) 2000-09-29
DZ2360A1 (fr) 2002-12-28
HUP0000544A3 (en) 2002-01-28
US6268509B1 (en) 2001-07-31
DE69719547T2 (de) 2003-10-02
EP0946515B1 (en) 2003-03-05
HUP0000544A2 (hu) 2000-06-28
IL129866A0 (en) 2000-02-29
NO992736D0 (no) 1999-06-04
CN1106386C (zh) 2003-04-23
SK285203B6 (sk) 2006-08-03
NO992732L (no) 1999-08-05
PL190926B1 (pl) 2006-02-28
HRP970663A2 (en) 1998-10-31
BG103454A (en) 2000-01-31
EA199900447A1 (ru) 2000-02-28
CA2273951A1 (en) 1998-06-11
CZ295295B6 (cs) 2005-06-15
CO5031251A1 (es) 2001-04-27
NO313518B1 (no) 2002-10-14
EP0946515A1 (en) 1999-10-06
JP3950483B2 (ja) 2007-08-01
IS1982B (is) 2005-01-14
CA2273951C (en) 2003-04-01
NO992732D0 (no) 1999-06-04
ES2191870T3 (es) 2003-09-16
OA11055A (en) 2002-03-07
KR100354311B1 (ko) 2002-09-28
JP2000505812A (ja) 2000-05-16
CN1258282A (zh) 2000-06-28
EA002278B1 (ru) 2002-02-28
TNSN97197A1 (fr) 2005-03-15
UA60321C2 (uk) 2003-10-15
BR9713565A (pt) 2000-03-14
AR013879A1 (es) 2001-01-31
IS5050A (is) 1999-05-11
RS49720B (sr) 2007-12-31
TW524667B (en) 2003-03-21
KR20000057432A (ko) 2000-09-15
HRP970663B1 (en) 2003-10-31
IL129866A (en) 2004-05-12
MA24414A1 (fr) 1998-07-01
AU5485998A (en) 1998-06-29
PT946515E (pt) 2003-06-30
SK74099A3 (en) 2001-02-12
MY117021A (en) 2004-04-30
CZ195199A3 (cs) 2000-08-16

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