UY24798A1 - Pirazoles parasiticidas - Google Patents
Pirazoles parasiticidasInfo
- Publication number
- UY24798A1 UY24798A1 UY24798A UY24798A UY24798A1 UY 24798 A1 UY24798 A1 UY 24798A1 UY 24798 A UY24798 A UY 24798A UY 24798 A UY24798 A UY 24798A UY 24798 A1 UY24798 A1 UY 24798A1
- Authority
- UY
- Uruguay
- Prior art keywords
- alkyl
- hydrogen
- optionally substituted
- cycloalkyl group
- independently selected
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyridine Compounds (AREA)
Abstract
Esta invención se refiere a derivados de pirazol que poseen propiedades parasiticidas. Más particularmente, se refiere a 1-aril-4-ciclopropilpirazoles. La presente invención proporciona compuestos de fórmula (I) o las sales aceptables desde el punto de vista farmacéutico, veterinario o agrícola de los mismos, o solvatos aceptables desde el punto de vista farmacéutico, veterinario o agrícola de cualquiera de las entidades, en la que: R1 es fenilo 2,4,6-trisustituido, en el que los sustituyentes en 2 y 6 se seleccionan independientemente entre halógeno, y el sustituyente 4 se selecciona entre alquilo, opcionalmente sustituido; R3 es alquilo opcionalmente sustituido con hidroxi o con uno o más halógenos; ciano, alcanoílo p fenilo; R5 es hidrógeno, alquilo, amino o halógeno; R2 y R4 se seleccionan cada uno, independientemente, entre hidrógeno, alquilo, fluoro, cloro y bromo o, junto al átomo de carbono al que se encuentran unidos, forman un grupo cicloalquilo; R6 y R8 se seleccionan cada uno, independientemente, entre hidrógeno, alquilo, fluoro, cloro y bromo; o cuando R2 y R4 no forman parte de un grupo cicloalquilo, R2 y R6, junto con los átomos de carbono a los que se encuentran unidos, pueden formar un grupo cicloalquilo; R7 es hidrógeno, alquilo opcionalmente sustituido. Por ejemplo: 3-ciano-4-(2,2-dibromociclopropil)-1-(2,6-dicloro-4-trifluorometilfenil)pirazol. Los compuestos de la invención poseen actividad parasiticida en humanos, animales y plantas, siendo particularmente útiles en el tratamiento de ectoparásitos.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UY24923A UY24923A1 (es) | 1996-12-05 | 1998-03-12 | Procedimiento para preparacion de pirazoles parasiticidas |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9625290.3A GB9625290D0 (en) | 1996-12-05 | 1996-12-05 | Parasiticidal agents |
| GBGB9702235.4A GB9702235D0 (en) | 1997-02-04 | 1997-02-04 | Parasiticidal agents |
| GBGB9712045.5A GB9712045D0 (en) | 1997-06-10 | 1997-06-10 | Parasiticidal agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY24798A1 true UY24798A1 (es) | 2000-09-29 |
Family
ID=27268619
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY24798A UY24798A1 (es) | 1996-12-05 | 1997-12-03 | Pirazoles parasiticidas |
| UY24923A UY24923A1 (es) | 1996-12-05 | 1998-03-12 | Procedimiento para preparacion de pirazoles parasiticidas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY24923A UY24923A1 (es) | 1996-12-05 | 1998-03-12 | Procedimiento para preparacion de pirazoles parasiticidas |
Country Status (40)
| Country | Link |
|---|---|
| US (2) | US6075043A (es) |
| EP (1) | EP0946515B1 (es) |
| JP (2) | JP3950483B2 (es) |
| KR (1) | KR100354311B1 (es) |
| CN (1) | CN1106386C (es) |
| AR (1) | AR013879A1 (es) |
| AT (1) | ATE233736T1 (es) |
| AU (1) | AU720705B2 (es) |
| BG (1) | BG64127B1 (es) |
| BR (1) | BR9713565A (es) |
| CA (1) | CA2273951C (es) |
| CO (1) | CO5031251A1 (es) |
| CZ (1) | CZ295295B6 (es) |
| DE (1) | DE69719547T2 (es) |
| DK (1) | DK0946515T3 (es) |
| DZ (1) | DZ2360A1 (es) |
| EA (1) | EA002278B1 (es) |
| ES (1) | ES2191870T3 (es) |
| HK (1) | HK1029111A1 (es) |
| HR (1) | HRP970663B1 (es) |
| HU (1) | HUP0000544A3 (es) |
| ID (1) | ID21556A (es) |
| IL (1) | IL129866A (es) |
| IS (1) | IS1982B (es) |
| MA (1) | MA24414A1 (es) |
| MY (1) | MY117021A (es) |
| NO (2) | NO992736D0 (es) |
| NZ (1) | NZ335611A (es) |
| OA (1) | OA11055A (es) |
| PA (1) | PA8442101A1 (es) |
| PE (1) | PE20199A1 (es) |
| PL (1) | PL190926B1 (es) |
| PT (1) | PT946515E (es) |
| RS (1) | RS49720B (es) |
| SK (1) | SK285203B6 (es) |
| TN (1) | TNSN97197A1 (es) |
| TW (1) | TW524667B (es) |
| UA (1) | UA60321C2 (es) |
| UY (2) | UY24798A1 (es) |
| WO (1) | WO1998024767A1 (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW524667B (en) | 1996-12-05 | 2003-03-21 | Pfizer | Parasiticidal pyrazoles |
| GB9801851D0 (en) * | 1998-01-29 | 1998-03-25 | Pfizer Ltd | Parasiticidal agents |
| GB9811050D0 (en) * | 1998-05-22 | 1998-07-22 | Pfizer Ltd | Pyrazoles |
| US6531501B1 (en) | 1998-12-11 | 2003-03-11 | Aventis Cropscience, S.A. | Control of arthropods in animals |
| AR021608A1 (es) * | 1998-12-11 | 2002-07-31 | Merial Ltd | Represion de artropodos en animales |
| GB9916052D0 (en) * | 1999-07-08 | 1999-09-08 | Pfizer Ltd | Anthelmintic compositions |
| CO5261614A1 (es) | 1999-12-02 | 2003-03-31 | Aventis Cropsience S A | Control de artropodos en animales |
| AU2003218758A1 (en) * | 2002-03-14 | 2003-09-22 | Syngenta Participations Ag | Derivatives of 1-phenyl-3-phenylpyrazole as herbicides |
| CH697663B1 (de) * | 2003-01-07 | 2009-01-15 | Lanxess Deutschland Gmbh | Pyrazolylalkine. |
| WO2005023773A1 (en) * | 2003-09-04 | 2005-03-17 | Pfizer Limited | Process for the preparation of substituted aryl pyrazoles |
| US7514464B2 (en) | 2003-12-18 | 2009-04-07 | Pfizer Limited | Substituted arylpyrazoles |
| GB0329314D0 (en) * | 2003-12-18 | 2004-01-21 | Pfizer Ltd | Substituted arylpyrazoles |
| WO2005090313A1 (en) | 2004-03-18 | 2005-09-29 | Pfizer Limited | N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides |
| CN101228134A (zh) | 2005-06-15 | 2008-07-23 | 辉瑞有限公司 | 用作杀寄生虫剂的取代芳基吡唑 |
| US7645786B2 (en) | 2005-06-15 | 2010-01-12 | Pfizer Inc. | Substituted arylpyrazoles |
| US20070149464A1 (en) * | 2005-06-15 | 2007-06-28 | Pfizer Inc. | Combination |
| US20080176865A1 (en) * | 2005-06-15 | 2008-07-24 | Pfizer Limited | Substituted arylpyrazoles |
| US20080146643A1 (en) * | 2005-06-15 | 2008-06-19 | Pfizer Limited | Combination |
| CA2614282A1 (en) | 2005-07-06 | 2007-01-11 | Sepracor Inc. | Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders |
| EP1783114A1 (en) * | 2005-11-03 | 2007-05-09 | Novartis AG | N-(hetero)aryl indole derivatives as pesticides |
| DE102006061537A1 (de) | 2006-12-27 | 2008-07-03 | Bayer Healthcare Ag | Mittel zur Bekämpfung von Parasiten an Tieren |
| DE102006061538A1 (de) | 2006-12-27 | 2008-07-03 | Bayer Healthcare Ag | Kombinationsprodukt zur Bekämpfung von Parasiten an Tieren |
| MX2012011549A (es) | 2010-04-08 | 2013-01-29 | Ah Usa 42 Llc | Derivados de 3,5-difenil-isoxazolina sustituida como insecticidas y acaricidas. |
| EP2601190B1 (en) | 2010-08-05 | 2018-07-04 | Zoetis Services LLC | Isoxazoline derivatives as antiparasitic agents |
| ES2793481T3 (es) | 2010-09-24 | 2020-11-16 | Zoetis Services Llc | Oximas de isoxazolina como agentes antiparasitarios |
| RS54860B1 (sr) | 2011-03-10 | 2016-10-31 | Zoetis Services Llc | Spirociklični derivati izoksazolina kao antiparazitska sredstva |
| CN103562190A (zh) | 2011-03-22 | 2014-02-05 | 佐蒂斯有限责任公司 | 作为抗寄生虫药的异噁唑啉衍生物 |
| BR112013033914A2 (pt) | 2011-06-30 | 2016-11-22 | Hansen Ab Gmbh | agente para o controle de parasitas em animais e uso de um agente |
| PL2814825T3 (pl) | 2012-02-03 | 2016-08-31 | Zoetis Services Llc | Dihydrofuranowe pochodne azetydyny jako środki przeciwpasożytnicze |
| JO3626B1 (ar) | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
| JP6049866B2 (ja) | 2012-05-09 | 2016-12-21 | ゾエティス・サービシーズ・エルエルシー | 駆虫剤としてのアゼチジン誘導体 |
| WO2014093481A1 (en) | 2012-12-12 | 2014-06-19 | Zoetis Llc | Phenylpyrazole injectable compositions |
| TWI762706B (zh) | 2017-08-24 | 2022-05-01 | 丹麥商諾佛 儂迪克股份有限公司 | Glp-1組成物及其用途 |
| CN111116478B (zh) * | 2019-12-18 | 2021-10-26 | 浙江金伯士药业有限公司 | 一种兽用抗生素维吉霉素中间体的制备方法 |
| BR112022013795A2 (pt) | 2020-02-18 | 2022-09-13 | Novo Nordisk As | Composição farmacêutica líquida, e, kit |
| CN115894374A (zh) * | 2023-02-16 | 2023-04-04 | 广州佳途科技股份有限公司 | 一种氟甲腈的制备方法及其应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2658725A1 (de) * | 1976-12-24 | 1978-07-06 | Bayer Ag | Mittel zur bekaempfung von tierischen ektoparasiten mit stark ausgepraegter residualwirkung |
| US4479968A (en) | 1980-10-17 | 1984-10-30 | The Wellcome Foundation Ltd. | Control of ectoparasitic infestations of pigs |
| GB2086302A (en) * | 1980-10-24 | 1982-05-12 | Bone Cravens Ltd | Prefill Valve System |
| GB8713768D0 (en) * | 1987-06-12 | 1987-07-15 | May & Baker Ltd | Compositions of matter |
| US5547974A (en) * | 1985-12-20 | 1996-08-20 | Rhone-Poulenc Agriculture Ltd. | Derivatives of N-phenylpyrazoles |
| GB8713769D0 (en) * | 1987-06-12 | 1987-07-15 | May & Baker Ltd | Compositions of matter |
| US5232940A (en) * | 1985-12-20 | 1993-08-03 | Hatton Leslie R | Derivatives of N-phenylpyrazoles |
| GB8531485D0 (en) * | 1985-12-20 | 1986-02-05 | May & Baker Ltd | Compositions of matter |
| GB8613914D0 (en) * | 1986-06-07 | 1986-07-09 | Coopers Animal Health | Liquid formulations |
| ES2037740T3 (es) * | 1986-12-05 | 1993-07-01 | Ciba-Geigy Ag | Formulacion ectoparasiticida no acuosa para aplicar en liquido por el sistema "pour on". |
| DE3706993A1 (de) * | 1987-03-05 | 1988-09-15 | Bayer Ag | 5-amino-3-halogenalkyl-1-aryl-pyrazole |
| SE455750B (sv) | 1987-06-11 | 1988-08-01 | Ericsson Telefon Ab L M | Digitalt tidsmultiplext mobiltelefonisystem med ett effektivt utnyttjande av varje tidsram |
| GB9120641D0 (en) * | 1991-09-27 | 1991-11-06 | Ici Plc | Heterocyclic compounds |
| ZA94170B (en) * | 1993-01-20 | 1995-03-15 | Soltec Res Pty Ltd | Ectoparasiticidal formulation |
| AUPM437194A0 (en) * | 1994-03-11 | 1994-03-31 | Commonwealth Scientific And Industrial Research Organisation | Pesticide formulation |
| GB9601128D0 (en) * | 1995-08-11 | 1996-03-20 | Pfizer Ltd | Parasiticidal compounds |
| ES2221934T3 (es) | 1995-08-11 | 2005-01-16 | Novozymes A/S | Nuevas enzimas lipoliticas. |
| JPH0987111A (ja) * | 1995-09-27 | 1997-03-31 | Sumitomo Chem Co Ltd | 害虫駆除用毒餌剤 |
| FR2739255B1 (fr) * | 1995-09-29 | 1998-09-04 | Rhone Merieux | Composition antiparasitaire pour le traitement et la protection des animaux de compagnie |
| ES2191076T3 (es) * | 1995-12-19 | 2003-09-01 | Bayer Cropscience Sa | Nuevos derivados de 1-aril-pirazol y su empleo como plaguicidas. |
| IE970215A1 (en) * | 1996-03-29 | 1997-10-08 | Rhone Merieux | Direct pour-on skin solution for antiparasitic use in cattle¹and sheep |
| GR1002899B (el) * | 1996-03-29 | 1998-05-11 | Rhone Merieux | Περιλαιμιο κατα ψυλλων και κροτωνων για σκυλους και γατες, με βαση ν-φαινυλπυραζολη |
| IE80657B1 (en) * | 1996-03-29 | 1998-11-04 | Merial Sas | Insecticidal combination to control mammal fleas in particular fleas on cats and dogs |
| GR970100096A (el) * | 1996-03-29 | 1997-11-28 | Merial | Εξωτερικη διαταξη κατα των παρασιτων για βοοειδη με βαση τη ν-φαινυλπυραζολη, ειδικα σκουλαρικια. |
| TW524667B (en) | 1996-12-05 | 2003-03-21 | Pfizer | Parasiticidal pyrazoles |
| US7100379B2 (en) * | 2003-08-14 | 2006-09-05 | Samsung Electronics Co., Ltd. | Water supply control apparatus and method for ice maker |
-
1997
- 1997-10-24 TW TW086115810A patent/TW524667B/zh not_active IP Right Cessation
- 1997-11-25 SK SK740-99A patent/SK285203B6/sk not_active IP Right Cessation
- 1997-11-25 DE DE69719547T patent/DE69719547T2/de not_active Expired - Lifetime
- 1997-11-25 EA EA199900447A patent/EA002278B1/ru not_active IP Right Cessation
- 1997-11-25 JP JP52517898A patent/JP3950483B2/ja not_active Expired - Fee Related
- 1997-11-25 UA UA99052678A patent/UA60321C2/uk unknown
- 1997-11-25 BR BR9713565-8A patent/BR9713565A/pt not_active Application Discontinuation
- 1997-11-25 AT AT97951271T patent/ATE233736T1/de active
- 1997-11-25 KR KR1019997005032A patent/KR100354311B1/ko not_active IP Right Cessation
- 1997-11-25 ID IDW990469A patent/ID21556A/id unknown
- 1997-11-25 EP EP97951271A patent/EP0946515B1/en not_active Expired - Lifetime
- 1997-11-25 PL PL333922A patent/PL190926B1/pl not_active IP Right Cessation
- 1997-11-25 WO PCT/EP1997/006697 patent/WO1998024767A1/en active IP Right Grant
- 1997-11-25 CN CN97180334A patent/CN1106386C/zh not_active Expired - Fee Related
- 1997-11-25 DK DK97951271T patent/DK0946515T3/da active
- 1997-11-25 ES ES97951271T patent/ES2191870T3/es not_active Expired - Lifetime
- 1997-11-25 US US09/319,310 patent/US6075043A/en not_active Expired - Lifetime
- 1997-11-25 AU AU54859/98A patent/AU720705B2/en not_active Ceased
- 1997-11-25 RS YUP-252/99A patent/RS49720B/sr unknown
- 1997-11-25 IL IL12986697A patent/IL129866A/en not_active IP Right Cessation
- 1997-11-25 HU HU0000544A patent/HUP0000544A3/hu unknown
- 1997-11-25 CA CA002273951A patent/CA2273951C/en not_active Expired - Fee Related
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- 1997-12-03 DZ DZ970210A patent/DZ2360A1/xx active
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1998
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1999
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2000
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2007
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| Date | Code | Title | Description |
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| VENC | Patent expired |
Effective date: 20171203 |