AU580990B2 - 3-``3-(quaternaryammonio)-1-propen-1-yl``-3-cephem derivatives - Google Patents

3-``3-(quaternaryammonio)-1-propen-1-yl``-3-cephem derivatives

Info

Publication number
AU580990B2
AU580990B2 AU40862/85A AU4086285A AU580990B2 AU 580990 B2 AU580990 B2 AU 580990B2 AU 40862/85 A AU40862/85 A AU 40862/85A AU 4086285 A AU4086285 A AU 4086285A AU 580990 B2 AU580990 B2 AU 580990B2
Authority
AU
Australia
Prior art keywords
quaternaryammonio
propen
cephem derivatives
cephem
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU40862/85A
Other languages
English (en)
Other versions
AU4086285A (en
Inventor
Takayuki Naito
Masahisa Oka
Jun Okumura
Haruhiro Yamashita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of AU4086285A publication Critical patent/AU4086285A/en
Application granted granted Critical
Publication of AU580990B2 publication Critical patent/AU580990B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/081,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78Separation; Purification; Stabilisation; Use of additives
    • C07C45/79Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU40862/85A 1984-04-09 1985-04-04 3-``3-(quaternaryammonio)-1-propen-1-yl``-3-cephem derivatives Expired AU580990B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59794184A 1984-04-09 1984-04-09
US597941 1984-04-09

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU25041/88A Division AU610278B2 (en) 1984-04-09 1988-11-11 Novel intermediates of cephalosporin derivatives

Publications (2)

Publication Number Publication Date
AU4086285A AU4086285A (en) 1985-10-17
AU580990B2 true AU580990B2 (en) 1989-02-09

Family

ID=24393575

Family Applications (2)

Application Number Title Priority Date Filing Date
AU40862/85A Expired AU580990B2 (en) 1984-04-09 1985-04-04 3-``3-(quaternaryammonio)-1-propen-1-yl``-3-cephem derivatives
AU25041/88A Expired AU610278B2 (en) 1984-04-09 1988-11-11 Novel intermediates of cephalosporin derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU25041/88A Expired AU610278B2 (en) 1984-04-09 1988-11-11 Novel intermediates of cephalosporin derivatives

Country Status (31)

Country Link
JP (4) JPS615084A (fr)
KR (1) KR870002166B1 (fr)
AR (1) AR244694A1 (fr)
AT (1) AT388735B (fr)
AU (2) AU580990B2 (fr)
BE (1) BE902148A (fr)
CA (3) CA1276929C (fr)
CH (1) CH669197A5 (fr)
DD (3) DD249024A5 (fr)
DE (1) DE3512225A1 (fr)
DK (1) DK155985A (fr)
ES (4) ES8607318A1 (fr)
FI (1) FI84830C (fr)
FR (1) FR2563832B1 (fr)
GB (3) GB2157293B (fr)
GR (1) GR850883B (fr)
HU (2) HU193750B (fr)
IE (2) IE58408B1 (fr)
IL (1) IL74826A (fr)
IT (1) IT1190353B (fr)
LU (1) LU85840A1 (fr)
MY (1) MY101940A (fr)
NL (1) NL192925C (fr)
NZ (1) NZ211659A (fr)
OA (1) OA07985A (fr)
PT (1) PT80246B (fr)
RU (1) RU2056425C1 (fr)
SE (4) SE466205B (fr)
SU (4) SU1436882A3 (fr)
YU (2) YU46151B (fr)
ZA (1) ZA852236B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61145186A (ja) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd 新規セフエム化合物及びその製造法
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
ATE114657T1 (de) * 1985-12-26 1994-12-15 Eisai Co Ltd Cephalosporin-verbindungen.
AU614723B2 (en) * 1986-10-13 1991-09-12 Eisai Co. Ltd. 3-propenylcephem derivative
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
JPH085897B2 (ja) * 1986-11-06 1996-01-24 エーザイ株式会社 3−プロペニルセフェム誘導体
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
JPH0699449B2 (ja) * 1988-03-16 1994-12-07 エーザイ株式会社 セフェム誘導体の合成中間体
ATE212027T1 (de) * 1988-03-16 2002-02-15 Eisai Co Ltd Cephemderivate und verfahren zu ihrer herstellung
FR2655042B1 (fr) * 1989-11-29 1994-01-21 Adir Cie Nouvelles benzothiazolinones substituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
JPH0741484A (ja) * 1993-07-29 1995-02-10 Katayama Seiyakushiyo:Kk セフェム化合物及び抗菌剤
EP0723966A4 (fr) * 1994-08-16 1997-01-29 Meiji Seika Co Nouveau derive de cepheme
TR200003807T2 (tr) 1998-06-22 2001-06-21 Basilea Pharmaceutica Ag Propenil sefalosporin türevleri
WO2005026176A1 (fr) 2003-09-09 2005-03-24 Nippon Chemical Industrial Co.,Ltd. Procede de production de derives de 3-chloromethyl-3-cepheme

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2134522A (en) * 1983-02-10 1984-08-15 Bristol Myers Co Cephalosporin derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
EP0025017A1 (fr) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Composés polyazathia, procédé pour leur préparation, compositions pharmaceutiques les contenant et utilisation de ces dernières
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
GR75644B (fr) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
GR78245B (fr) * 1980-09-12 1984-09-26 Ciba Geigy Ag
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2134522A (en) * 1983-02-10 1984-08-15 Bristol Myers Co Cephalosporin derivatives

Also Published As

Publication number Publication date
IL74826A (en) 1990-01-18
GB2157293B (en) 1988-10-05
ZA852236B (en) 1985-11-27
HU193750B (en) 1987-11-30
GB8508846D0 (en) 1985-05-09
FR2563832A1 (fr) 1985-11-08
GB2194790B (en) 1988-10-05
ES551550A0 (es) 1987-06-01
JPH0350754B2 (fr) 1991-08-02
GB2157293A (en) 1985-10-23
SU1436882A3 (ru) 1988-11-07
JPH0351716B2 (fr) 1991-08-07
RU2056425C1 (ru) 1996-03-20
MY101940A (en) 1992-02-15
ES8800949A1 (es) 1987-12-01
AU610278B2 (en) 1991-05-16
GB2194790A (en) 1988-03-16
NL8501002A (nl) 1985-11-01
GR850883B (fr) 1985-11-25
HUT37622A (en) 1986-01-23
ES8706694A1 (es) 1987-07-01
SU1367858A3 (ru) 1988-01-15
YU46151B (sh) 1993-05-28
DD251752A5 (de) 1987-11-25
SE8901224L (sv) 1989-04-06
CA1276929C (fr) 1990-11-27
SE8501680L (sv) 1985-10-10
IE58408B1 (en) 1993-09-22
CH669197A5 (de) 1989-02-28
SE8501680D0 (sv) 1985-04-03
FI84830B (fi) 1991-10-15
IL74826A0 (en) 1985-07-31
ATA103985A (de) 1989-01-15
SE505256C2 (sv) 1997-07-21
ES557060A0 (es) 1987-12-01
PT80246B (pt) 1987-10-20
HU204277B (en) 1991-12-30
PT80246A (en) 1985-05-01
JPH0357106B2 (fr) 1991-08-30
SU1375140A3 (ru) 1988-02-15
ES551551A0 (es) 1987-07-01
DE3512225C2 (fr) 1990-02-22
GB2194789A (en) 1988-03-16
FI851379L (fi) 1985-10-10
JPS61143390A (ja) 1986-07-01
JPS61143387A (ja) 1986-07-01
OA07985A (fr) 1987-01-31
SE8901225D0 (sv) 1989-04-06
CA1340638C (fr) 1999-07-06
GB8721347D0 (en) 1987-10-14
YU46213B (sh) 1993-05-28
IT8520267A0 (it) 1985-04-05
JPS615084A (ja) 1986-01-10
ES8607318A1 (es) 1986-06-16
JPH0262557B2 (fr) 1990-12-26
KR870002166B1 (ko) 1987-12-14
SE466205B (sv) 1992-01-13
LU85840A1 (fr) 1985-12-16
FI851379A0 (fi) 1985-04-04
CA1340672C (fr) 1999-07-20
NL192925B (nl) 1998-01-05
FR2563832B1 (fr) 1989-08-18
ES8706155A1 (es) 1987-06-01
KR850007424A (ko) 1985-12-04
IE58403B1 (en) 1993-09-22
GB8721346D0 (en) 1987-10-14
AT388735B (de) 1989-08-25
NZ211659A (en) 1988-11-29
YU118987A (en) 1988-10-31
SE8901225L (sv) 1989-04-06
SE8901226L (sv) 1989-04-06
AR244694A1 (es) 1993-11-30
JPS61143391A (ja) 1986-07-01
SE8901224D0 (sv) 1989-04-06
NL192925C (nl) 1998-05-07
SE470259B (sv) 1993-12-20
DK155985D0 (da) 1985-04-03
DK155985A (da) 1985-10-10
ES542013A0 (es) 1986-06-16
YU60085A (en) 1987-12-31
DD249024A5 (de) 1987-08-26
DD236735A5 (de) 1986-06-18
FI84830C (fi) 1992-01-27
IE850866L (en) 1985-10-09
GB2194789B (en) 1988-10-12
DE3512225A1 (de) 1985-10-17
AU4086285A (en) 1985-10-17
IT1190353B (it) 1988-02-16
SE470260B (sv) 1993-12-20
SU1487814A3 (ru) 1989-06-15
SE8901226D0 (sv) 1989-04-06
BE902148A (fr) 1985-10-09
AU2504188A (en) 1989-03-02

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