ATE313532T1 - Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen - Google Patents

Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen

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Publication number
ATE313532T1
ATE313532T1 AT04758159T AT04758159T ATE313532T1 AT E313532 T1 ATE313532 T1 AT E313532T1 AT 04758159 T AT04758159 T AT 04758159T AT 04758159 T AT04758159 T AT 04758159T AT E313532 T1 ATE313532 T1 AT E313532T1
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Austria
Prior art keywords
ht2a
diaryl
prophylaxis
modulators
treatment
Prior art date
Application number
AT04758159T
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German (de)
English (en)
Inventor
Bradley Teegarden
Honnappa Jayakumar
Hongmei Li
Sonja Strah-Pleynet
Peter Ian Dosa
Original Assignee
Arena Pharm Inc
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Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
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Publication of ATE313532T1 publication Critical patent/ATE313532T1/de

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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AT04758159T 2003-07-22 2004-07-21 Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen ATE313532T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48957203P 2003-07-22 2003-07-22
US50358603P 2003-09-16 2003-09-16
PCT/US2004/023488 WO2005012254A1 (en) 2003-07-22 2004-07-21 Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related therto

Publications (1)

Publication Number Publication Date
ATE313532T1 true ATE313532T1 (de) 2006-01-15

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AT04758159T ATE313532T1 (de) 2003-07-22 2004-07-21 Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen

Country Status (29)

Country Link
US (9) US8754238B2 (enExample)
EP (1) EP1558582B1 (enExample)
JP (3) JP4198733B2 (enExample)
KR (1) KR101157272B1 (enExample)
CN (3) CN101871931A (enExample)
AR (1) AR045069A1 (enExample)
AT (1) ATE313532T1 (enExample)
AU (1) AU2004261582C1 (enExample)
BR (1) BRPI0412263B1 (enExample)
CA (1) CA2533369C (enExample)
DE (1) DE602004000260T2 (enExample)
DK (1) DK1558582T3 (enExample)
EA (1) EA009732B1 (enExample)
EC (1) ECSP066269A (enExample)
ES (1) ES2258760T3 (enExample)
HR (1) HRP20060100T3 (enExample)
IL (1) IL172582A0 (enExample)
IS (1) IS2232B (enExample)
MA (1) MA28066A1 (enExample)
MX (1) MXPA06000795A (enExample)
MY (1) MY141862A (enExample)
NO (1) NO20060877L (enExample)
NZ (1) NZ544331A (enExample)
PL (1) PL1558582T3 (enExample)
PT (1) PT1558582E (enExample)
RS (1) RS20060035A (enExample)
TN (1) TNSN06017A1 (enExample)
TW (1) TW200523253A (enExample)
WO (1) WO2005012254A1 (enExample)

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JP4198733B2 (ja) 2003-07-22 2008-12-17 アリーナ ファーマシューティカルズ， インコーポレイテッド 関連性障害の予防および処置に有用な、５−ｈｔ２ａセロトニンレセプターのモジュレーターとしてのジアリールおよびアリールへテロアリールウレア誘導体
EP1727803B3 (en) * 2004-03-23 2014-04-23 Arena Pharmaceuticals, Inc. Processes for preparing substituted n-aryl-n'-[3-(1h-pyrazol-5-yl)phenyl] ureas and intermediates thereof
SA05260357B1 (ar) * 2004-11-19 2008-09-08 ارينا فارماسيتو تيكالز ، أنك مشتقات 3_فينيل_بيرازول كمعدلات لمستقبل سيروتينين 5_ht2a مفيدة في علاج الاضطرابات المتعلقه به
WO2006060762A2 (en) * 2004-12-03 2006-06-08 Arena Pharmaceuticals, Inc. Pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
WO2006078610A1 (en) * 2005-01-19 2006-07-27 Arena Pharmaceuticals, Inc. Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis or treatment of progressive multifocal leukoencephalopathy
AR052886A1 (es) * 2005-01-26 2007-04-11 Arena Pharm Inc Procedimientos para preparar fenilpirazol ureas sustituidas y para la obtencion de sus intermediarios de sintesis
WO2006089871A2 (en) * 2005-02-23 2006-08-31 Neurosearch A/S Diphenylurea derivatives useful as erg channel openers for the treatment of cardiac arrhythmias
JP4559262B2 (ja) 2005-03-07 2010-10-06 学校法人関西医科大学 動脈硬化および糖尿病性腎障害の判定方法
EA200800971A1 (ru) * 2005-09-29 2008-08-29 Арена Фармасьютикалз, Инк. Фармацевтические композиции модулятора 5-нтрецепторов серотонина, полезные в лечении связанных с ними нарушений
JP5406018B2 (ja) 2006-05-18 2014-02-05 アリーナ ファーマシューティカルズ， インコーポレイテッド ５−ｈｔ２ａセロトニンレセプターに関連する障害の処置に有用な５−ｈｔ２ａセロトニンレセプターのモジュレーターとしての１級アミン、およびその誘導体
NZ571829A (en) * 2006-05-18 2011-10-28 Arena Pharm Inc Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-HT2A serotonin receptor
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