ATE424823T1 - 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydrochinolin- derivate als arzneimittel zur behandlung von unfruchtbarkeit - Google Patents
4-phenyl-5-oxo-1,4,5,6,7,8-hexahydrochinolin- derivate als arzneimittel zur behandlung von unfruchtbarkeitInfo
- Publication number
- ATE424823T1 ATE424823T1 AT06754952T AT06754952T ATE424823T1 AT E424823 T1 ATE424823 T1 AT E424823T1 AT 06754952 T AT06754952 T AT 06754952T AT 06754952 T AT06754952 T AT 06754952T AT E424823 T1 ATE424823 T1 AT E424823T1
- Authority
- AT
- Austria
- Prior art keywords
- hexahydrocinoline
- infertility
- oxo
- phenyl
- derivatives
- Prior art date
Links
- 208000000509 infertility Diseases 0.000 title 1
- 230000036512 infertility Effects 0.000 title 1
- 231100000535 infertility Toxicity 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05103738 | 2005-05-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE424823T1 true ATE424823T1 (de) | 2009-03-15 |
Family
ID=34939695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06754952T ATE424823T1 (de) | 2005-05-04 | 2006-05-02 | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydrochinolin- derivate als arzneimittel zur behandlung von unfruchtbarkeit |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US8034945B2 (de) |
| EP (1) | EP1879580B1 (de) |
| JP (1) | JP5129738B2 (de) |
| KR (1) | KR20080010427A (de) |
| CN (1) | CN101212972B (de) |
| AR (1) | AR056338A1 (de) |
| AT (1) | ATE424823T1 (de) |
| AU (1) | AU2006243190B2 (de) |
| BR (1) | BRPI0611118A2 (de) |
| CA (1) | CA2606682C (de) |
| CY (1) | CY1109076T1 (de) |
| DE (1) | DE602006005640D1 (de) |
| DK (1) | DK1879580T3 (de) |
| ES (1) | ES2322295T3 (de) |
| HR (1) | HRP20090189T1 (de) |
| IL (1) | IL186676A (de) |
| MX (1) | MX2007013742A (de) |
| NO (1) | NO20075567L (de) |
| NZ (1) | NZ562685A (de) |
| PE (1) | PE20061440A1 (de) |
| PL (1) | PL1879580T3 (de) |
| PT (1) | PT1879580E (de) |
| RS (1) | RS50968B (de) |
| RU (1) | RU2403243C2 (de) |
| SI (1) | SI1879580T1 (de) |
| UA (1) | UA92008C2 (de) |
| WO (1) | WO2006117370A1 (de) |
| ZA (1) | ZA200709094B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA92007C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности |
| UA92009C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия |
| DE602005027002D1 (en) * | 2005-05-04 | 2011-04-28 | Organon Nv | Dihydropyridinderivate |
| TW200944523A (en) | 2008-02-08 | 2009-11-01 | Organon Nv | (Dihydro)pyrrolo[2,1-a]isoquinolines |
| US8071587B2 (en) | 2009-05-27 | 2011-12-06 | N. V. Organon | (Dihydro)imidazoiso[5,1-A]quinolines |
| TW201116531A (en) | 2009-07-29 | 2011-05-16 | Organon Nv | Ring-annulated dihydropyrrolo[2,1-a]isoquinolines |
| US8431564B2 (en) | 2009-07-29 | 2013-04-30 | Merck Sharp & Dohme B.V. | Ring-annulated dihydropyrrolo[2,1-α]isoquinolines |
| TW201116515A (en) | 2009-07-31 | 2011-05-16 | Organon Nv | Dihydrobenzoindazoles |
| KR20130089232A (ko) | 2010-06-15 | 2013-08-09 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 안트라닐산 디아미드 유도체 |
| RU2648352C1 (ru) * | 2017-07-18 | 2018-03-23 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Способ лечения первичного бесплодия, обусловленного тромбофилиями при проведении экстракорпорального оплодотворения |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1070162B (de) | 1959-12-03 | Farbwerke Hoechst Aktiengesellschaft vormals Meister Lucius &. Brüning, Frankfurt/M | Verfahren zur Herstellung von 5 - Brom - 3 - nitro - 4 - hydroxybenzaldehyd bzw. 5 - Chlor - 3 - nitro - 4 - hydroxybenzaldehyd | |
| US5455253A (en) * | 1992-10-20 | 1995-10-03 | Zeneca Limited | Heterocyclic derivatives |
| GB9318935D0 (en) * | 1992-10-20 | 1993-10-27 | Zeneca Ltd | Heterocyclic derivatives |
| GB9407432D0 (en) * | 1994-04-14 | 1994-06-08 | Zeneca Ltd | Heterocyclic derivative |
| DE4430639A1 (de) * | 1994-08-29 | 1996-03-07 | Bayer Ag | Verwendung von 5-substituierten Pyridin- und Hexahydrochinolin-3-carbonsäurederivaten |
| GB9515445D0 (en) | 1995-07-27 | 1995-09-27 | Pharmacia Spa | Dihydropyridine and pyridine derivatives and process for their preparation |
| CN1200114A (zh) * | 1995-10-19 | 1998-11-25 | 武田药品工业株式会社 | 作为gnrh拮抗剂的喹啉衍生物 |
| US6593335B1 (en) * | 1997-12-18 | 2003-07-15 | Abbott Laboratories | Potassium channel openers |
| IL141063A (en) | 1998-08-07 | 2005-06-19 | Applied Research Systems | Derivatives of pyrrolidine-2-carboxylic acid and piperidine-2-carboxylic acids and pharmaceutical compositions comprising said derivatives for treating infertility |
| EP1307193A1 (de) | 2000-07-27 | 2003-05-07 | Affymax Research Institute | Agonisten mit aktivität bezüglich des follikel-stimulierenden hormons |
| HUP0400390A2 (hu) | 2001-07-02 | 2004-09-28 | Akzo Nobel N.V. | Tetrahidrokinolin-származékok és ezeket tartalmazó gyógyszerkészítmények |
| JP2003026630A (ja) | 2001-07-13 | 2003-01-29 | Taoka Chem Co Ltd | カラーカプラー中間体用カルボン酸クロリド類の製造法 |
| TWI322012B (en) * | 2002-12-20 | 2010-03-21 | Organon Nv | Tetrahydroquinoline derivatives |
| UA92009C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия |
| DE602005027002D1 (en) * | 2005-05-04 | 2011-04-28 | Organon Nv | Dihydropyridinderivate |
| UA92007C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности |
-
2006
- 2006-02-05 UA UAA200711803A patent/UA92008C2/ru unknown
- 2006-05-02 RS RSP-2009/0251A patent/RS50968B/sr unknown
- 2006-05-02 RU RU2007144988/04A patent/RU2403243C2/ru not_active IP Right Cessation
- 2006-05-02 JP JP2008509436A patent/JP5129738B2/ja not_active Expired - Fee Related
- 2006-05-02 EP EP06754952A patent/EP1879580B1/de active Active
- 2006-05-02 DE DE602006005640T patent/DE602006005640D1/de active Active
- 2006-05-02 PL PL06754952T patent/PL1879580T3/pl unknown
- 2006-05-02 ES ES06754952T patent/ES2322295T3/es active Active
- 2006-05-02 HR HR20090189T patent/HRP20090189T1/xx unknown
- 2006-05-02 BR BRPI0611118-1A patent/BRPI0611118A2/pt not_active IP Right Cessation
- 2006-05-02 WO PCT/EP2006/061976 patent/WO2006117370A1/en not_active Ceased
- 2006-05-02 AT AT06754952T patent/ATE424823T1/de active
- 2006-05-02 NZ NZ562685A patent/NZ562685A/en not_active IP Right Cessation
- 2006-05-02 CA CA2606682A patent/CA2606682C/en not_active Expired - Fee Related
- 2006-05-02 DK DK06754952T patent/DK1879580T3/da active
- 2006-05-02 US US11/912,746 patent/US8034945B2/en active Active
- 2006-05-02 CN CN2006800237472A patent/CN101212972B/zh not_active Expired - Fee Related
- 2006-05-02 PT PT06754952T patent/PT1879580E/pt unknown
- 2006-05-02 KR KR1020077026920A patent/KR20080010427A/ko not_active Ceased
- 2006-05-02 SI SI200630269T patent/SI1879580T1/sl unknown
- 2006-05-02 AU AU2006243190A patent/AU2006243190B2/en not_active Ceased
- 2006-05-02 MX MX2007013742A patent/MX2007013742A/es active IP Right Grant
- 2006-05-03 AR ARP060101780A patent/AR056338A1/es not_active Application Discontinuation
- 2006-05-03 PE PE2006000468A patent/PE20061440A1/es not_active Application Discontinuation
-
2007
- 2007-10-16 IL IL186676A patent/IL186676A/en not_active IP Right Cessation
- 2007-10-22 ZA ZA200709094A patent/ZA200709094B/xx unknown
- 2007-11-05 NO NO20075567A patent/NO20075567L/no not_active Application Discontinuation
-
2009
- 2009-05-19 CY CY20091100532T patent/CY1109076T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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