AU2003275093A1 - Process of making phenylpyrazoles useful as selective 5ht2a modulators and intermediates thereof - Google Patents

Process of making phenylpyrazoles useful as selective 5ht2a modulators and intermediates thereof

Info

Publication number
AU2003275093A1
AU2003275093A1 AU2003275093A AU2003275093A AU2003275093A1 AU 2003275093 A1 AU2003275093 A1 AU 2003275093A1 AU 2003275093 A AU2003275093 A AU 2003275093A AU 2003275093 A AU2003275093 A AU 2003275093A AU 2003275093 A1 AU2003275093 A1 AU 2003275093A1
Authority
AU
Australia
Prior art keywords
phenylpyrazoles
modulators
intermediates
useful
making
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003275093A
Other versions
AU2003275093A8 (en
Inventor
Keith Drouet
Katie Elwell
Konrad Feichtinger
Stefan Horns
Max Ray
Bradley Teegarden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arena Pharmaceuticals Inc
Original Assignee
Arena Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharmaceuticals Inc filed Critical Arena Pharmaceuticals Inc
Publication of AU2003275093A1 publication Critical patent/AU2003275093A1/en
Publication of AU2003275093A8 publication Critical patent/AU2003275093A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003275093A 2002-09-24 2003-09-22 Process of making phenylpyrazoles useful as selective 5ht2a modulators and intermediates thereof Abandoned AU2003275093A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41329902P 2002-09-24 2002-09-24
US60/413,299 2002-09-24
PCT/US2003/029736 WO2004028450A2 (en) 2002-09-24 2003-09-22 Process of making phenylpyrazoles useful as selective 5ht2a modulators and intermediates thereof

Publications (2)

Publication Number Publication Date
AU2003275093A1 true AU2003275093A1 (en) 2004-04-19
AU2003275093A8 AU2003275093A8 (en) 2004-04-19

Family

ID=32043230

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003275093A Abandoned AU2003275093A1 (en) 2002-09-24 2003-09-22 Process of making phenylpyrazoles useful as selective 5ht2a modulators and intermediates thereof

Country Status (2)

Country Link
AU (1) AU2003275093A1 (en)
WO (1) WO2004028450A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1558582E (en) 2003-07-22 2006-05-31 Arena Pharm Inc DIARIL- AND ARIL-HETEROARIL-UREA DERIVATIVES AS SEROTONIN 5-HT2A RECEPTOR MODULES USEFUL FOR PROPHYLAXIS AND TREATMENT OF RELEVANT DISORDERS
ATE548353T1 (en) 2004-03-23 2012-03-15 Arena Pharm Inc METHOD FOR PRODUCING SUBSTITUTED N-ARYL-N'-Ä3-(1H-PYRAZOLE-5-YL)PHENYLÜ-UREAS AND INTERMEDIATE THEREOF.
SA05260357B1 (en) 2004-11-19 2008-09-08 ارينا فارماسيتو تيكالز ، أنك 3-phenyle-pyrazole derivatives as modulators of the 5-ht 2a serotonin receptor useful for the treatment of disorders related thereto
AR052886A1 (en) * 2005-01-26 2007-04-11 Arena Pharm Inc PROCEDURES TO PREPARE PHENYLPIRAZOL REPLACED UREAS AND TO OBTAIN YOUR SYNTHESIS INTERMEDIARIES
USRE45336E1 (en) 2006-05-18 2015-01-13 Arena Pharmaceuticals, Inc. Primary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
USRE45337E1 (en) 2006-05-18 2015-01-13 Arena Pharmaceuticals, Inc. Ethers, secondary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
CA2646081C (en) 2006-05-18 2017-06-27 Arena Pharmaceuticals, Inc. Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-ht2a serotonin receptor
TWI415845B (en) 2006-10-03 2013-11-21 Arena Pharm Inc Pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
ES2421237T7 (en) 2007-08-15 2013-09-30 Arena Pharmaceuticals, Inc. Imidazo [1,2-a] pyridine derivatives as modulators of the serotonergic 5ht2a receptor in the treatment of disorders related thereto
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
PT2364142T (en) 2008-10-28 2018-04-23 Arena Pharm Inc Compositions of a 5-ht2a serotonin receptor modulator useful for the treatment of disorders related thereto
WO2011075596A1 (en) 2009-12-18 2011-06-23 Arena Pharmaceuticals, Inc. Crystalline forms of certain 3-phenyl-pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
RU2017145976A (en) 2015-06-12 2019-07-15 Аксовант Сайенсиз Гмбх Diaryl- and arylheteroarylurea derivatives applicable for the prevention and treatment of behavioral disturbances during the REM phase of sleep
KR20180064373A (en) 2015-07-15 2018-06-14 엑소반트 사이언시즈 게엠베하 Diaryl and aryl heteroaryl urea derivatives as modulators of 5-HT2A serotonin receptors useful for the prevention and treatment of hallucinations associated with neurodegenerative diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2682379B1 (en) * 1991-10-09 1994-02-11 Rhone Poulenc Agrochimie NEW FUNGICIDAL PHENYLPYRAZOLES.

Also Published As

Publication number Publication date
WO2004028450A3 (en) 2004-10-07
WO2004028450A2 (en) 2004-04-08
AU2003275093A8 (en) 2004-04-19

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase