ATE285774T1 - Ranolazinhaltige arzneimittel mit verzögerter wirkstoffabgabe - Google Patents
Ranolazinhaltige arzneimittel mit verzögerter wirkstoffabgabeInfo
- Publication number
- ATE285774T1 ATE285774T1 AT99948196T AT99948196T ATE285774T1 AT E285774 T1 ATE285774 T1 AT E285774T1 AT 99948196 T AT99948196 T AT 99948196T AT 99948196 T AT99948196 T AT 99948196T AT E285774 T1 ATE285774 T1 AT E285774T1
- Authority
- AT
- Austria
- Prior art keywords
- delayed release
- products containing
- medicinal products
- ranolazine
- containing ranolazine
- Prior art date
Links
- XKLMZUWKNUAPSZ-UHFFFAOYSA-N N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide Chemical compound COC1=CC=CC=C1OCC(O)CN1CCN(CC(=O)NC=2C(=CC=CC=2C)C)CC1 XKLMZUWKNUAPSZ-UHFFFAOYSA-N 0.000 title 1
- 230000003111 delayed effect Effects 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 229960000213 ranolazine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9980498P | 1998-09-10 | 1998-09-10 | |
| US09/321,522 US6303607B1 (en) | 1998-09-10 | 1999-05-27 | Method for administering a sustained release ranolanolazine formulation |
| PCT/US1999/020968 WO2000013687A2 (en) | 1998-09-10 | 1999-09-09 | Sustained release ranolazine formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE285774T1 true ATE285774T1 (de) | 2005-01-15 |
Family
ID=26796494
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99948196T ATE285774T1 (de) | 1998-09-10 | 1999-09-09 | Ranolazinhaltige arzneimittel mit verzögerter wirkstoffabgabe |
| AT99968627T ATE217794T1 (de) | 1998-09-10 | 1999-09-09 | Ranolazinhaltige arzneimittel mit verzögerter wirkstoffabgabe |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99968627T ATE217794T1 (de) | 1998-09-10 | 1999-09-09 | Ranolazinhaltige arzneimittel mit verzögerter wirkstoffabgabe |
Country Status (33)
| Country | Link |
|---|---|
| US (14) | US6303607B1 (OSRAM) |
| EP (3) | EP1096937B9 (OSRAM) |
| JP (2) | JP3745621B2 (OSRAM) |
| KR (1) | KR100475759B1 (OSRAM) |
| CN (2) | CN1211086C (OSRAM) |
| AR (3) | AR022085A1 (OSRAM) |
| AT (2) | ATE285774T1 (OSRAM) |
| AU (4) | AU760435B2 (OSRAM) |
| BR (2) | BR9913626A (OSRAM) |
| CA (2) | CA2343376C (OSRAM) |
| CY (1) | CY2008020I1 (OSRAM) |
| CZ (2) | CZ301375B6 (OSRAM) |
| DE (3) | DE69922964T2 (OSRAM) |
| DK (2) | DK1096937T3 (OSRAM) |
| ES (2) | ES2177346T3 (OSRAM) |
| FR (1) | FR09C0001I2 (OSRAM) |
| GE (1) | GEP20053420B (OSRAM) |
| HK (1) | HK1044284B (OSRAM) |
| HU (2) | HUP0104088A3 (OSRAM) |
| IL (6) | IL141893A0 (OSRAM) |
| LU (1) | LU91504I2 (OSRAM) |
| MX (2) | MXPA01002599A (OSRAM) |
| NL (1) | NL300371I2 (OSRAM) |
| NO (4) | NO319434B1 (OSRAM) |
| NZ (2) | NZ510386A (OSRAM) |
| PL (3) | PL196263B1 (OSRAM) |
| PT (2) | PT1109558E (OSRAM) |
| RU (2) | RU2214233C2 (OSRAM) |
| SI (2) | SI1109558T1 (OSRAM) |
| TR (2) | TR200101261T2 (OSRAM) |
| TW (1) | TWI241911B (OSRAM) |
| UA (2) | UA67793C2 (OSRAM) |
| WO (2) | WO2000013687A2 (OSRAM) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6479496B1 (en) * | 1998-09-10 | 2002-11-12 | Cv Therapeutics, Inc. | Methods for treating angina with ranolazine |
| US6303607B1 (en) * | 1998-09-10 | 2001-10-16 | Cv Therapeutics, Inc. | Method for administering a sustained release ranolanolazine formulation |
| MXPA02007639A (es) | 2000-02-18 | 2004-08-23 | Cv Therapeutics Inc | Inhibidores de la oxidacion parcial de los acidos grasos en el tratamiento de la falla cardiaca congestiva. |
| US20020052377A1 (en) * | 2000-07-21 | 2002-05-02 | Wolff Andrew A. | Method for treating angina |
| AU2001211213A1 (en) * | 2000-10-20 | 2002-04-29 | Galephar M/F | Stable oral formulation containing benzimidazole derivative |
| FR2830447B1 (fr) * | 2001-10-09 | 2004-04-16 | Flamel Tech Sa | Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques |
| US8101209B2 (en) * | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
| US20080109040A1 (en) * | 2002-04-04 | 2008-05-08 | Luiz Belardinelli | Method of treating arrhythmias |
| US20030220344A1 (en) * | 2002-04-04 | 2003-11-27 | Luiz Belardinelli | Method of treating arrhythmias |
| JP4732696B2 (ja) | 2002-04-09 | 2011-07-27 | フラメル・テクノロジー | 活性成分の改変された放出のための、マイクロカプセルの水性懸濁液形態での経口医薬品製剤 |
| AU2003246791A1 (en) * | 2002-04-09 | 2003-10-20 | Flamel Technologies | Oral suspension of amoxicillin capsules |
| US20040063717A1 (en) | 2002-05-21 | 2004-04-01 | Andrew Wolff | Method of treating diabetes |
| US8822473B2 (en) * | 2002-05-21 | 2014-09-02 | Gilead Sciences, Inc. | Method of treating diabetes |
| GB0403098D0 (en) | 2004-02-12 | 2004-03-17 | Euro Celtique Sa | Extrusion |
| TWI350762B (en) | 2004-02-12 | 2011-10-21 | Euro Celtique Sa | Particulates |
| WO2006074398A2 (en) * | 2005-01-06 | 2006-07-13 | Cv Therapeutics, Inc. | Sustained release pharmaceutical formulations comprising ranolazine |
| FR2886150B1 (fr) * | 2005-05-24 | 2007-08-24 | Flamel Technologies Sa | Forme pharmaceutique orale a base d'au moins un principe actif dont la solubilite varie en fonction des conditions de ph gastrique |
| JP2009502957A (ja) * | 2005-07-28 | 2009-01-29 | スパーナス ファーマシューティカルズ インコーポレイテッド | 機械的特性の向上した徐放性錠剤配合物 |
| WO2007108362A1 (ja) * | 2006-03-17 | 2007-09-27 | Konica Minolta Holdings, Inc. | 有機エレクトロルミネッセンス素子、表示装置および照明装置 |
| FI20060501A7 (fi) * | 2006-05-22 | 2007-11-23 | Biohit Oyj | Koostumus ja menetelmä asetaldehydin sitomiseksi mahalaukussa |
| WO2008101012A1 (en) * | 2007-02-13 | 2008-08-21 | Cv Therapeutics, Inc. | Use of ranolazine for the treatment of non-coronary microvascular diseases |
| US20090111826A1 (en) * | 2007-02-13 | 2009-04-30 | Louis Lange | Use of ranolazine for the treatment of cardiovascular diseases |
| US20090312340A1 (en) * | 2007-02-13 | 2009-12-17 | Whedy Wang | Use of ranolazine for the treatment of cardiovascular diseases |
| JP2010518169A (ja) * | 2007-02-13 | 2010-05-27 | ギリアード・パロ・アルト・インコーポレイテッド | 心血管疾患の処置のためのラノラジンの使用 |
| US20080248112A1 (en) * | 2007-02-13 | 2008-10-09 | Brent Blackburn | Use of ranolazine for the treatment of coronary microvascular diseases |
| ES2395241T3 (es) * | 2007-03-07 | 2013-02-11 | Concert Pharmaceuticals Inc. | Derivados deuterados de piperazina como compuestos antianginosos |
| US20080233191A1 (en) * | 2007-03-22 | 2008-09-25 | Brent Blackburn | Use of ranolazine for elevated brain-type natriuretic peptide |
| CN101896181A (zh) * | 2007-05-31 | 2010-11-24 | 吉利德帕洛阿尔托股份有限公司 | 用于升高的脑钠肽的雷诺嗪 |
| RU2442585C2 (ru) * | 2007-05-31 | 2012-02-20 | Си Ви Терапьютикс, Инк. | Способ лечения диабета |
| CN101066253B (zh) * | 2007-06-07 | 2011-01-05 | 北京本草天源药物研究院 | 一种雷诺嗪缓释片 |
| AU2008266124A1 (en) * | 2007-06-13 | 2008-12-24 | Auspex Pharmaceuticals, Inc. | Substituted piperazines |
| US20090012103A1 (en) * | 2007-07-05 | 2009-01-08 | Matthew Abelman | Substituted heterocyclic compounds |
| US20090076018A1 (en) * | 2007-09-15 | 2009-03-19 | Protia, Llc | Deuterium-enriched ranolazine |
| WO2009100380A1 (en) * | 2008-02-06 | 2009-08-13 | Cv Therapeutics, Inc. | Use of ranolazine for treating pain |
| WO2010132696A1 (en) * | 2009-05-14 | 2010-11-18 | Gilead Palo Alto, Inc. | Ranolazine for the treatment of cns disorders |
| US8901128B2 (en) | 2009-05-28 | 2014-12-02 | Lupin Limited | Pharmaceutical compositions of ranolazine |
| EP2480234B1 (en) | 2009-09-25 | 2020-02-26 | Lupin Limited | Sustained release composition of ranolazine |
| TWI508726B (zh) | 2009-12-21 | 2015-11-21 | Gilead Sciences Inc | 治療心房纖維性顫動之方法 |
| TW201215392A (en) | 2010-06-16 | 2012-04-16 | Gilead Sciences Inc | Use of ranolazine for treating pulmonary hypertension |
| ES2414384T3 (es) | 2011-05-11 | 2013-07-19 | Ratiopharm Gmbh | Composición de liberación modificada que comprende ranolazina |
| NO3175985T3 (OSRAM) | 2011-07-01 | 2018-04-28 | ||
| AU2012312266A1 (en) | 2011-09-21 | 2013-05-02 | Gilead Sciences, Inc. | Sodium channel blockers reduce glucagon secretion |
| WO2014176567A2 (en) * | 2013-04-26 | 2014-10-30 | Chanrx Corporation | Pharmaceutical compositions comprising vanoxerine and antianginal compounds, and methods of administration of the same for treating episodes of cardiac arrhythmia, maintaining normal sinus rhythm, preventing recurrence of cardiac arrhythmia, and treatment of chronic cardiac arrhythmia in mammals |
| CN104758265B (zh) * | 2014-01-07 | 2019-05-17 | 四川海思科制药有限公司 | 一种雷诺嗪缓释片药物组合物及其制备方法 |
| AR101476A1 (es) | 2014-08-07 | 2016-12-21 | Acerta Pharma Bv | Métodos para tratar cánceres, enfermedades inmunes y autoinmunes, y enfermedades inflamatorias en base a la tasa de ocupación de la tirosin quinasa de bruton (btk) y a la tasa de resíntesis de la tirosin quinasa de bruton (btk) |
| TW201717919A (zh) * | 2015-07-02 | 2017-06-01 | 國際藥品股份公司 | 雷諾多重壓縮錠劑 |
| WO2018001582A1 (en) | 2016-06-30 | 2018-01-04 | Interquim, S.A. | Ranolazine multiple compressed tablets |
| AR110252A1 (es) | 2016-11-30 | 2019-03-13 | Gilead Sciences Inc | Compuestos heterocíclicos fusionados como inhibidores de la quinasa cam |
| US10898444B2 (en) * | 2017-06-01 | 2021-01-26 | Sun Pharmaceutical Industries Limited | Extended release multiparticulates of ranolazine |
| CN112438955A (zh) * | 2019-08-30 | 2021-03-05 | 深圳翰宇药业股份有限公司 | 一种雷诺嗪缓释组合物及其制备方法 |
| WO2021126884A1 (en) | 2019-12-16 | 2021-06-24 | Tenax Therapeutics, Inc. | LEVOSIMENDAN FOR TREATING PULMONARY HYPERTENSION WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION (PH-HF-pEF) |
| CN110898024A (zh) * | 2019-12-17 | 2020-03-24 | 卓和药业集团有限公司 | 一种治疗心绞痛的药物组合物及制备方法 |
| GR1010345B (el) * | 2021-12-16 | 2022-11-28 | Φαρματεν Α.Β.Ε.Ε., | Δισκια παρατεταμενης αποδεσμευσης που περιλαμβανουν ρανολαζινη και μεθοδος παραγωγης αυτων |
| US20250064799A1 (en) | 2021-12-31 | 2025-02-27 | Tenax Therapeutics, Inc. | Oral formulations of levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction |
| GR1010510B (el) * | 2022-06-07 | 2023-07-20 | Ελπεν Α.Ε. Φαρμακευτικη Βιομηχανια, | Στερεες φαρμακοτεχνικες μορφες παρατεταμενης αποδεσμευσης ρανολαζινης |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4567264A (en) | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
| IL81419A0 (en) * | 1986-01-30 | 1987-08-31 | Syntex Inc | Long acting sustained release pharmaceutical compositions containing dihydropyridines and their preparation |
| DK0719558T3 (da) * | 1989-06-23 | 2002-10-07 | Syntex Llc | Ranolzin og beslægtede piperazin til anvendelse ved behandling af chocktilstande |
| US5527545A (en) | 1989-09-18 | 1996-06-18 | Recordati S.A. Chemical And Pharmaceutical Company | Liquid-suspension controlled-release pharmaceutical composition |
| US5209933A (en) * | 1990-01-10 | 1993-05-11 | Syntex (U.S.A.) Inc. | Long acting calcium channel blocker composition |
| JP2516524B2 (ja) * | 1992-04-27 | 1996-07-24 | 大洋薬品工業株式会社 | 持続性製剤 |
| JPH06199657A (ja) * | 1992-12-10 | 1994-07-19 | Sumitomo Pharmaceut Co Ltd | 徐放性製剤 |
| US5455045A (en) | 1993-05-13 | 1995-10-03 | Syntex (U.S.A.) Inc. | High dose formulations |
| JPH07112932A (ja) * | 1993-08-27 | 1995-05-02 | Mitsui Toatsu Chem Inc | 徐放性医薬製剤 |
| US5525606A (en) * | 1994-08-01 | 1996-06-11 | The United States Of America As Represented By The Department Of Health And Human Services | Substituted 06-benzylguanines and 6(4)-benzyloxypyrimidines |
| JPH08259446A (ja) * | 1995-01-24 | 1996-10-08 | Mitsui Toatsu Chem Inc | 持効性医薬製剤 |
| JPH08310946A (ja) * | 1995-05-19 | 1996-11-26 | Yuutoku Yakuhin Kogyo Kk | 経皮吸収製剤 |
| JPH09188617A (ja) * | 1996-01-08 | 1997-07-22 | Pola Chem Ind Inc | 徐放性医薬組成物 |
| US6479496B1 (en) * | 1998-09-10 | 2002-11-12 | Cv Therapeutics, Inc. | Methods for treating angina with ranolazine |
| US6303607B1 (en) * | 1998-09-10 | 2001-10-16 | Cv Therapeutics, Inc. | Method for administering a sustained release ranolanolazine formulation |
-
1999
- 1999-05-27 US US09/321,522 patent/US6303607B1/en not_active Expired - Lifetime
- 1999-09-09 RU RU2001109431/14A patent/RU2214233C2/ru active Protection Beyond IP Right Term
- 1999-09-09 CA CA002343376A patent/CA2343376C/en not_active Expired - Lifetime
- 1999-09-09 CZ CZ20010879A patent/CZ301375B6/cs not_active IP Right Cessation
- 1999-09-09 NZ NZ510386A patent/NZ510386A/en not_active IP Right Cessation
- 1999-09-09 DE DE69922964T patent/DE69922964T2/de not_active Expired - Lifetime
- 1999-09-09 BR BR9913626-0A patent/BR9913626A/pt not_active Application Discontinuation
- 1999-09-09 JP JP2000568494A patent/JP3745621B2/ja not_active Expired - Lifetime
- 1999-09-09 TR TR2001/01261T patent/TR200101261T2/xx unknown
- 1999-09-09 IL IL14189399A patent/IL141893A0/xx active IP Right Grant
- 1999-09-09 RU RU2001109432/14A patent/RU2207856C2/ru active
- 1999-09-09 UA UA2001031623A patent/UA67793C2/uk unknown
- 1999-09-09 KR KR10-2001-7003126A patent/KR100475759B1/ko not_active Expired - Lifetime
- 1999-09-09 PT PT99968627T patent/PT1109558E/pt unknown
- 1999-09-09 DK DK99948196T patent/DK1096937T3/da active
- 1999-09-09 CA CA002342390A patent/CA2342390C/en not_active Expired - Lifetime
- 1999-09-09 AR ARP990104545A patent/AR022085A1/es active IP Right Grant
- 1999-09-09 EP EP99948196A patent/EP1096937B9/en not_active Expired - Lifetime
- 1999-09-09 AT AT99948196T patent/ATE285774T1/de active
- 1999-09-09 AU AU61425/99A patent/AU760435B2/en not_active Revoked
- 1999-09-09 IL IL14189299A patent/IL141892A0/xx active IP Right Grant
- 1999-09-09 GE GE4322A patent/GEP20053420B/en unknown
- 1999-09-09 EP EP99968627A patent/EP1109558B1/en not_active Expired - Lifetime
- 1999-09-09 ES ES99968627T patent/ES2177346T3/es not_active Expired - Lifetime
- 1999-09-09 HK HK02105856.0A patent/HK1044284B/zh not_active IP Right Cessation
- 1999-09-09 CZ CZ20010880A patent/CZ301341B6/cs not_active IP Right Cessation
- 1999-09-09 CN CNB998108359A patent/CN1211086C/zh not_active Expired - Lifetime
- 1999-09-09 ES ES99948196T patent/ES2234302T3/es not_active Expired - Lifetime
- 1999-09-09 MX MXPA01002599A patent/MXPA01002599A/es active IP Right Grant
- 1999-09-09 NZ NZ510384A patent/NZ510384A/xx not_active IP Right Cessation
- 1999-09-09 MX MXPA01002598A patent/MXPA01002598A/es active IP Right Grant
- 1999-09-09 AT AT99968627T patent/ATE217794T1/de active
- 1999-09-09 TR TR2001/01262T patent/TR200101262T2/xx unknown
- 1999-09-09 HU HU0104088A patent/HUP0104088A3/hu unknown
- 1999-09-09 AU AU60364/99A patent/AU744071B2/en not_active Revoked
- 1999-09-09 EP EP04030151A patent/EP1527779A1/en not_active Withdrawn
- 1999-09-09 DK DK99968627T patent/DK1109558T3/da active
- 1999-09-09 CN CNB998108367A patent/CN1193757C/zh not_active Expired - Lifetime
- 1999-09-09 WO PCT/US1999/020968 patent/WO2000013687A2/en not_active Ceased
- 1999-09-09 PL PL348249A patent/PL196263B1/pl unknown
- 1999-09-09 PL PL347073A patent/PL196668B1/pl unknown
- 1999-09-09 HU HU0103844A patent/HU224215B1/hu active Protection Beyond IP Right Term
- 1999-09-09 PT PT99948196T patent/PT1096937E/pt unknown
- 1999-09-09 UA UA2001031622A patent/UA75027C2/uk unknown
- 1999-09-09 SI SI9930078T patent/SI1109558T1/xx unknown
- 1999-09-09 SI SI9930749T patent/SI1096937T1/xx unknown
- 1999-09-09 WO PCT/US1999/020967 patent/WO2000013686A2/en not_active Ceased
- 1999-09-09 DE DE69901570T patent/DE69901570T2/de not_active Expired - Lifetime
- 1999-09-09 PL PL381164A patent/PL202207B1/pl unknown
- 1999-09-09 DE DE122008000065C patent/DE122008000065I1/de active Pending
- 1999-09-09 BR BR9913553-1A patent/BR9913553A/pt not_active Application Discontinuation
-
2000
- 2000-03-29 US US09/538,337 patent/US6369062B1/en not_active Expired - Lifetime
- 2000-05-30 TW TW088115657A patent/TWI241911B/zh not_active IP Right Cessation
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2001
- 2001-03-07 IL IL141893A patent/IL141893A/en not_active IP Right Cessation
- 2001-03-07 IL IL141892A patent/IL141892A/en not_active IP Right Cessation
- 2001-03-08 NO NO20011191A patent/NO319434B1/no not_active IP Right Cessation
- 2001-03-08 NO NO20011192A patent/NO320986B1/no not_active IP Right Cessation
- 2001-08-09 US US09/925,871 patent/US6525057B2/en not_active Expired - Lifetime
- 2001-10-19 US US10/041,521 patent/US6503911B2/en not_active Expired - Lifetime
-
2002
- 2002-09-25 US US10/254,707 patent/US6562826B1/en not_active Expired - Lifetime
- 2002-09-27 US US10/256,993 patent/US6620814B2/en not_active Expired - Lifetime
- 2002-09-27 US US10/259,143 patent/US6617328B2/en not_active Expired - Lifetime
-
2003
- 2003-03-05 US US10/382,266 patent/US6852724B2/en not_active Expired - Lifetime
- 2003-07-07 US US10/614,420 patent/US20040097514A1/en not_active Abandoned
- 2003-07-07 US US10/614,460 patent/US6864258B2/en not_active Expired - Lifetime
-
2004
- 2004-10-21 US US10/969,891 patent/US20050059667A1/en not_active Abandoned
-
2005
- 2005-01-06 US US11/031,220 patent/US20050153982A1/en not_active Abandoned
- 2005-09-07 US US11/221,450 patent/US20060147521A1/en not_active Abandoned
- 2005-09-20 NO NO20054324A patent/NO20054324L/no unknown
- 2005-10-11 JP JP2005296674A patent/JP2006096757A/ja active Pending
- 2005-11-02 US US11/265,536 patent/US20060217397A1/en not_active Abandoned
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2006
- 2006-02-24 AR ARP060100700A patent/AR052921A1/es not_active Application Discontinuation
- 2006-02-24 AR ARP060100699A patent/AR053440A2/es not_active Application Discontinuation
- 2006-05-01 IL IL175371A patent/IL175371A0/en unknown
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2007
- 2007-01-22 IL IL180864A patent/IL180864A0/en unknown
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2008
- 2008-09-03 AU AU2008207707A patent/AU2008207707A1/en active Pending
- 2008-09-03 AU AU2008207703A patent/AU2008207703A1/en active Pending
- 2008-11-27 NL NL300371C patent/NL300371I2/nl unknown
- 2008-12-03 LU LU91504C patent/LU91504I2/fr unknown
- 2008-12-30 CY CY2008020C patent/CY2008020I1/el unknown
-
2009
- 2009-01-05 FR FR09C0001C patent/FR09C0001I2/fr active Active
- 2009-03-05 NO NO2009005C patent/NO2009005I1/no not_active IP Right Cessation
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