ATE277189T1 - Verfahren zur herstellung von protein mutanten mit reduzierter allergener wirkung in menschen. - Google Patents

Verfahren zur herstellung von protein mutanten mit reduzierter allergener wirkung in menschen.

Info

Publication number
ATE277189T1
ATE277189T1 AT99918575T AT99918575T ATE277189T1 AT E277189 T1 ATE277189 T1 AT E277189T1 AT 99918575 T AT99918575 T AT 99918575T AT 99918575 T AT99918575 T AT 99918575T AT E277189 T1 ATE277189 T1 AT E277189T1
Authority
AT
Austria
Prior art keywords
humans
producing protein
protein mutants
reduced allergenic
allergenic effects
Prior art date
Application number
AT99918575T
Other languages
English (en)
Inventor
David A Estell
Fiona A Harding
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22032273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE277189(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genencor Int filed Critical Genencor Int
Application granted granted Critical
Publication of ATE277189T1 publication Critical patent/ATE277189T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
AT99918575T 1998-04-15 1999-04-14 Verfahren zur herstellung von protein mutanten mit reduzierter allergener wirkung in menschen. ATE277189T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/060,872 US6835550B1 (en) 1998-04-15 1998-04-15 Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
PCT/US1999/008253 WO1999053038A2 (en) 1998-04-15 1999-04-14 Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins

Publications (1)

Publication Number Publication Date
ATE277189T1 true ATE277189T1 (de) 2004-10-15

Family

ID=22032273

Family Applications (2)

Application Number Title Priority Date Filing Date
AT99918575T ATE277189T1 (de) 1998-04-15 1999-04-14 Verfahren zur herstellung von protein mutanten mit reduzierter allergener wirkung in menschen.
AT04016880T ATE452195T1 (de) 1998-04-15 1999-04-14 Protease mutanten mit reduzierter allergener wirkung in menschen und methoden zur konstruktion,identifizierung und herstellung dieser proteasen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT04016880T ATE452195T1 (de) 1998-04-15 1999-04-14 Protease mutanten mit reduzierter allergener wirkung in menschen und methoden zur konstruktion,identifizierung und herstellung dieser proteasen

Country Status (20)

Country Link
US (4) US6835550B1 (de)
EP (3) EP1997897B1 (de)
JP (1) JP4447774B2 (de)
KR (1) KR20010034776A (de)
CN (1) CN1302113C (de)
AT (2) ATE277189T1 (de)
AU (1) AU752934B2 (de)
BR (1) BR9909640A (de)
CA (1) CA2327311C (de)
CZ (1) CZ20003789A3 (de)
DE (3) DE69920434T4 (de)
DK (3) DK1073754T3 (de)
ES (2) ES2338319T3 (de)
ID (1) ID26645A (de)
IL (2) IL138445A0 (de)
MX (2) MXPA05003288A (de)
NO (1) NO20005153L (de)
NZ (2) NZ506926A (de)
PL (1) PL343509A1 (de)
WO (1) WO1999053038A2 (de)

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ES2229703T3 (es) 2005-04-16
DE69941827D1 (de) 2010-01-28
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EP1073754A2 (de) 2001-02-07
DK1586649T3 (da) 2010-04-26
PL343509A1 (en) 2001-08-27
EP1073754B9 (de) 2005-01-19
CN1297484A (zh) 2001-05-30
IL138445A0 (en) 2001-10-31
DE69920434T2 (de) 2005-10-13
KR20010034776A (ko) 2001-04-25
EP1586649B1 (de) 2009-12-16
DK1997897T3 (da) 2013-02-11
NO20005153D0 (no) 2000-10-13
EP1997897B1 (de) 2012-11-14
IL138445A (en) 2013-05-30
US6596525B1 (en) 2003-07-22
US6835550B1 (en) 2004-12-28
US6218165B1 (en) 2001-04-17
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JP2002511251A (ja) 2002-04-16
NZ524596A (en) 2004-09-24
DE69920434D1 (de) 2004-10-28
ES2229703T4 (es) 2006-07-16
MXPA05003289A (es) 2005-09-08
EP1586649A2 (de) 2005-10-19
US20050137112A1 (en) 2005-06-23
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BR9909640A (pt) 2000-12-19
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ATE452195T1 (de) 2010-01-15
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