BR0215415A - Proteases produzindo uma resposta imunológica alterada e métodos de preparar e usar as mesmas - Google Patents
Proteases produzindo uma resposta imunológica alterada e métodos de preparar e usar as mesmasInfo
- Publication number
- BR0215415A BR0215415A BR0215415-3A BR0215415A BR0215415A BR 0215415 A BR0215415 A BR 0215415A BR 0215415 A BR0215415 A BR 0215415A BR 0215415 A BR0215415 A BR 0215415A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- preparing
- proteins
- relates
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cosmetics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"PROTEASES PRODUZINDO UMA RESPOSTA IMUNOLóGICA ALTERADA E MéTODOS DE PREPARAR E USAR AS MESMAS". A presente invenção refere-se a novas variantes de proteína que exibem respostas imunogênicas reduzidas, quando comparado às proteínas parentais. A presente invenção também refere-se a moléculas de DNA que codificam novas variantes, células hospedeiras compreendendo DNA codificando novas variantes, bem como métodos de preparar proteínas menos alergênicas. Além disso, a presente invenção refere-se a várias composições que compreendem estas proteínas que são menos imunogênicas do que as proteínas do tipo silvestre.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34465701P | 2001-12-31 | 2001-12-31 | |
PCT/US2002/041201 WO2003057246A1 (en) | 2001-12-31 | 2002-12-20 | Proteases producing an altered immunological response and methods of making and using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0215415A true BR0215415A (pt) | 2005-04-05 |
Family
ID=23351432
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0215415-3A BR0215415A (pt) | 2001-12-31 | 2002-12-20 | Proteases produzindo uma resposta imunológica alterada e métodos de preparar e usar as mesmas |
Country Status (7)
Country | Link |
---|---|
US (3) | US20050054843A1 (pt) |
EP (1) | EP1461072A4 (pt) |
JP (1) | JP2005514026A (pt) |
AU (1) | AU2002353178C1 (pt) |
BR (1) | BR0215415A (pt) |
CA (1) | CA2471972A1 (pt) |
WO (1) | WO2003057246A1 (pt) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK200101090A (da) * | 2001-07-12 | 2001-08-16 | Novozymes As | Subtilase variants |
US7294499B2 (en) | 2003-01-30 | 2007-11-13 | Novozymes A/S | Subtilases |
CN103820423A (zh) | 2004-04-02 | 2014-05-28 | 诺维信公司 | 具有改变的免疫原性的枯草杆菌酶变体 |
JP5647976B2 (ja) * | 2008-06-06 | 2015-01-07 | ダニスコ・ユーエス・インク | 変異体微生物プロテアーゼを含む組成物及び方法 |
DE102008062772A1 (de) | 2008-12-18 | 2010-06-24 | Henkel Ag & Co. Kgaa | Desinfektion von Viren an Textilien und harten Oberflächen |
WO2011072099A2 (en) * | 2009-12-09 | 2011-06-16 | Danisco Us Inc. | Compositions and methods comprising protease variants |
DE102010002196A1 (de) | 2010-02-22 | 2011-11-17 | Henkel Ag & Co. Kgaa | Kartusche für ein wasserführendes Haushaltsgerät |
DE102010038497A1 (de) | 2010-07-27 | 2012-02-02 | Henkel Ag & Co. Kgaa | Stabilisierte flüssige enzymhaltige Tensidzubereitung |
DE102010038498A1 (de) | 2010-07-27 | 2012-02-02 | Henkel Ag & Co. Kgaa | Stabilisierte flüssige enzymhaltige Tensidzubereitung |
DE102010038502A1 (de) | 2010-07-27 | 2012-02-02 | Henkel Ag & Co. Kgaa | Stabilisierte flüssige enzymhaltige Tensidzubereitung |
DE102010038501A1 (de) | 2010-07-27 | 2012-02-02 | Henkel Ag & Co. Kgaa | Stabilisierte flüssige enzymhaltige Tensidzubereitung |
DE102010038499A1 (de) | 2010-07-27 | 2012-02-02 | Henkel Ag & Co. Kgaa | Stabilisierte flüssige enzymhaltige Tensidzubereitung |
DE102010038496A1 (de) | 2010-07-27 | 2012-02-02 | Henkel Ag & Co. Kgaa | Stabilisierte flüssige enzymhaltige Tensidzubereitung |
DE102010043934A1 (de) | 2010-11-15 | 2012-05-16 | Henkel Ag & Co. Kgaa | Stabilisierte flüssige enzymhaltige Tensidzubereitung |
DE102011118027A1 (de) | 2011-09-12 | 2013-03-14 | Henkel Ag & Co. Kgaa | Verfahren zur Anpassung eines Hydrolytischen Enzyms an eine das hydrolytische Enzym stabilisierende Komponente |
WO2013092635A1 (en) * | 2011-12-20 | 2013-06-27 | Novozymes A/S | Subtilase variants and polynucleotides encoding same |
WO2017089093A1 (en) | 2015-11-25 | 2017-06-01 | Unilever N.V. | A liquid detergent composition |
EP3770240A1 (de) | 2019-07-22 | 2021-01-27 | Henkel AG & Co. KGaA | Geschirrspülmittel mit bleichkatalysator und bacillus gibsonii protease |
EP3770237A1 (de) | 2019-07-22 | 2021-01-27 | Henkel AG & Co. KGaA | Wasch- und reinigungsmittel mit verbesserter enzym-stabilität |
EP3770238A1 (de) | 2019-07-22 | 2021-01-27 | Henkel AG & Co. KGaA | Wasch- und reinigungsmittel mit protease und amylase |
DE102019126683A1 (de) | 2019-10-02 | 2021-04-08 | Henkel Ag & Co. Kgaa | Copolymere zur Verbesserung der Lagerstabilität von Enzymen in Wasch- und Reinigungsmitteln |
DE102020204505A1 (de) | 2020-04-07 | 2021-10-07 | Henkel Ag & Co. Kgaa | Wasch-/Pflegeartikel umfassend Pheromone |
DE102020205400A1 (de) | 2020-04-29 | 2021-11-04 | Henkel Ag & Co. Kgaa | Hochalkalisches Textilwaschmittel mit Protease |
DE102020205381A1 (de) | 2020-04-29 | 2021-11-04 | Henkel Ag & Co. Kgaa | Hochalkalisches Textilwaschmittel mit Protease |
DE102020131794A1 (de) | 2020-12-01 | 2022-06-02 | Henkel Ag & Co. Kgaa | Verbesserte Reinigung durch Hydrogencarbonat im maschinellen Geschirrspülmittel |
EP4012011A1 (de) | 2020-12-14 | 2022-06-15 | Henkel AG & Co. KGaA | Reinigungsmittel insbesondere für eine küchenmaschine |
WO2022128620A1 (de) | 2020-12-14 | 2022-06-23 | Henkel Ag & Co. Kgaa | Verfahren zur reinigung einer elektromotorisch betriebenen küchenmaschine |
DE102021213462A1 (de) | 2021-11-30 | 2023-06-01 | Henkel Ag & Co. Kgaa | Verfahren zur Reinigung einer elektromotorisch betriebenen Küchenmaschine |
EP4011256A1 (de) | 2020-12-14 | 2022-06-15 | Henkel AG & Co. KGaA | Verfahren zur reinigung einer elektromotorisch betriebenen küchenmaschine |
DE102020134229A1 (de) | 2020-12-18 | 2022-06-23 | Henkel Ag & Co. Kgaa | Getränktes Reinigungstuch |
DE102021116100A1 (de) | 2021-06-22 | 2022-12-22 | Henkel Ag & Co. Kgaa | Blooming-Effekt durch den Einsatz von löslichen Waschtüchern |
DE102021116096A1 (de) | 2021-06-22 | 2022-12-22 | Henkel Ag & Co. Kgaa | Reinigungsmittel |
EP4134423A1 (en) | 2021-08-12 | 2023-02-15 | Henkel AG & Co. KGaA | Sprayable laundry pre-treatment composition |
CN118742632A (zh) | 2022-02-24 | 2024-10-01 | 赢创运营有限公司 | 生物基组合物 |
DE102022107827A1 (de) | 2022-04-01 | 2023-10-05 | Henkel Ag & Co. Kgaa | Haarentfernung durch Waschmittel/-Additive enthaltend Enzyme |
DE102022205591A1 (de) | 2022-06-01 | 2023-12-07 | Henkel Ag & Co. Kgaa | Wasch- und reinigungsmittel mit verbesserter enzymstabilität |
DE102022205588A1 (de) | 2022-06-01 | 2023-12-07 | Henkel Ag & Co. Kgaa | Wasch- und reinigungsmittel mit verbesserter enzymstabilität |
DE102022205594A1 (de) | 2022-06-01 | 2023-12-07 | Henkel Ag & Co. Kgaa | Leistungsverbesserte und lagerstabile protease-varianten |
DE102022205593A1 (de) | 2022-06-01 | 2023-12-07 | Henkel Ag & Co. Kgaa | Wasch- und reinigungsmittel mit verbesserter enzymstabilität |
WO2024002738A1 (en) | 2022-06-28 | 2024-01-04 | Evonik Operations Gmbh | Composition comprising biosurfactant and persicomycin |
EP4324900A1 (en) | 2022-08-17 | 2024-02-21 | Henkel AG & Co. KGaA | Detergent composition comprising enzymes |
WO2024115213A1 (en) | 2022-11-30 | 2024-06-06 | Evonik Operations Gmbh | Detergent compartment pouch comprising biosurfactants |
DE102022131732A1 (de) | 2022-11-30 | 2024-06-06 | Henkel Ag & Co. Kgaa | Verbesserte Waschleistung durch den Einsatz einer Protease fusioniert mit speziellem Adhäsionsvermittlerpeptid |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
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US3755560A (en) * | 1971-06-30 | 1973-08-28 | Dow Chemical Co | Nongreasy cosmetic lotions |
DE2437090A1 (de) * | 1974-08-01 | 1976-02-19 | Hoechst Ag | Reinigungsmittel |
JPS51125468A (en) * | 1975-03-27 | 1976-11-01 | Sanyo Chem Ind Ltd | Method of preparing resins of high water absorbency |
US4152416A (en) * | 1976-09-17 | 1979-05-01 | Marra Dorothea C | Aerosol antiperspirant compositions delivering astringent salt with low mistiness and dustiness |
NL190101C (nl) * | 1978-11-13 | 1993-11-01 | Givaudan & Cie Sa | Dibenzoylmethaanverbinding en tegen licht beschermend preparaat. |
US4261868A (en) * | 1979-08-08 | 1981-04-14 | Lever Brothers Company | Stabilized enzymatic liquid detergent composition containing a polyalkanolamine and a boron compound |
DE3009104C2 (de) * | 1980-03-10 | 1990-10-04 | Odenwald-Chemie GmbH, 6901 Schönau | Verwendung eines Epoxydharzes zur Herstellung von feuerhemmenden Schichten oder Überzügen und Verfahren zur Herstellung derselben |
US4404128A (en) * | 1981-05-29 | 1983-09-13 | The Procter & Gamble Company | Enzyme detergent composition |
US4421769A (en) * | 1981-09-29 | 1983-12-20 | The Procter & Gamble Company | Skin conditioning composition |
JPS58144105A (ja) * | 1982-02-12 | 1983-08-27 | Kurabo Ind Ltd | スケ−ル除去獣毛繊維の製法 |
NZ208612A (en) * | 1983-06-24 | 1991-09-25 | Genentech Inc | Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations |
US4760025A (en) * | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
US5182204A (en) * | 1984-05-29 | 1993-01-26 | Genencor International, Inc. | Non-human carbonyl hydrolase mutants, vectors encoding same and hosts transformed with said vectors |
US5204015A (en) * | 1984-05-29 | 1993-04-20 | Genencor International, Inc. | Subtilisin mutants |
US5264366A (en) * | 1984-05-29 | 1993-11-23 | Genencor, Inc. | Protease deficient bacillus |
US5185258A (en) * | 1984-05-29 | 1993-02-09 | Genencor International, Inc. | Subtilisin mutants |
US4663157A (en) * | 1985-02-28 | 1987-05-05 | The Proctor & Gamble Company | Sunscreen compositions |
US4999186A (en) * | 1986-06-27 | 1991-03-12 | The Procter & Gamble Company | Novel sunscreen agents, sunscreen compositions and methods for preventing sunburn |
US4937370A (en) * | 1987-06-02 | 1990-06-26 | The Procter & Gamble Company | Novel chromophores, sunscreen compositions and methods for preventing sunburn |
DE3856302T2 (de) * | 1987-10-22 | 1999-09-09 | The Procter & Gamble Co. | Chelatbildner enthaltende Lichtschutzmittel |
US5087372A (en) * | 1989-03-24 | 1992-02-11 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for removing heavy metal ions from contaminated water and a porous membrane usable therefor |
US5011681A (en) * | 1989-10-11 | 1991-04-30 | Richardson-Vicks, Inc. | Facial cleansing compositions |
US5073372A (en) * | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
US5073371A (en) * | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
ATE170630T1 (de) * | 1990-12-05 | 1998-09-15 | Novo Nordisk As | Proteine mit geänderten epitopen und verfahren zur deren herstellung |
US5827508A (en) * | 1996-09-27 | 1998-10-27 | The Procter & Gamble Company | Stable photoprotective compositions |
JP2002512624A (ja) * | 1997-05-21 | 2002-04-23 | バイオベーション リミテッド | 非免疫原性タンパク質の製造方法 |
KR20010034697A (ko) * | 1998-03-26 | 2001-04-25 | 데이비드 엠 모이어 | 아미노산 치환을 갖는 세린 프로테아제 변이체 |
US6838269B1 (en) * | 1998-04-15 | 2005-01-04 | Genencor International, Inc. | Proteins producing an altered immunogenic response and methods of making and using the same |
US6835550B1 (en) * | 1998-04-15 | 2004-12-28 | Genencor International, Inc. | Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins |
US5935556A (en) * | 1998-07-30 | 1999-08-10 | The Procter & Gamble Company | Sunscreen compositions |
US5972316A (en) * | 1998-10-16 | 1999-10-26 | The Procter & Gamble Company | UV protection compositions |
US5968485A (en) * | 1998-10-16 | 1999-10-19 | The Procter & Gamble Company | UV protection compositions |
CN1373802A (zh) * | 1999-07-22 | 2002-10-09 | 宝洁公司 | 在特定表位区域具有氨基酸缺失和取代的枯草杆菌蛋白酶变体 |
US20020022040A1 (en) * | 2000-07-10 | 2002-02-21 | The Proctor & Gamble Company | Methods of enhancing delivery of oil-soluble skin care actives |
DK1373296T3 (da) * | 2001-03-23 | 2012-01-09 | Procter & Gamble | Proteiner, der frembringer et ændret immunogent respons, og fremgangsmåder til fremstilling og anvendelse deraf |
-
2002
- 2002-12-20 BR BR0215415-3A patent/BR0215415A/pt not_active Application Discontinuation
- 2002-12-20 EP EP02790158A patent/EP1461072A4/en not_active Withdrawn
- 2002-12-20 US US10/498,694 patent/US20050054843A1/en not_active Abandoned
- 2002-12-20 CA CA002471972A patent/CA2471972A1/en not_active Abandoned
- 2002-12-20 JP JP2003557603A patent/JP2005514026A/ja active Pending
- 2002-12-20 WO PCT/US2002/041201 patent/WO2003057246A1/en active Application Filing
- 2002-12-20 AU AU2002353178A patent/AU2002353178C1/en not_active Ceased
-
2008
- 2008-09-18 US US12/233,539 patent/US20140294881A1/en not_active Abandoned
-
2015
- 2015-01-09 US US14/593,951 patent/US20150152404A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2005514026A (ja) | 2005-05-19 |
AU2002353178C1 (en) | 2011-02-03 |
US20150152404A1 (en) | 2015-06-04 |
AU2002353178B2 (en) | 2008-05-29 |
WO2003057246A1 (en) | 2003-07-17 |
CA2471972A1 (en) | 2003-07-17 |
AU2002353178A1 (en) | 2003-07-24 |
US20140294881A1 (en) | 2014-10-02 |
US20050054843A1 (en) | 2005-03-10 |
EP1461072A1 (en) | 2004-09-29 |
EP1461072A4 (en) | 2005-02-09 |
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Legal Events
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B25D | Requested change of name of applicant approved |
Owner name: DANISCO US INC. (US) |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 24, 8O C/C 11, 8O C/C 13, 18 E 25 DA LPI. |
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B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |