DK1373296T3 - Proteiner, der frembringer et ændret immunogent respons, og fremgangsmåder til fremstilling og anvendelse deraf - Google Patents
Proteiner, der frembringer et ændret immunogent respons, og fremgangsmåder til fremstilling og anvendelse derafInfo
- Publication number
- DK1373296T3 DK1373296T3 DK02723603.3T DK02723603T DK1373296T3 DK 1373296 T3 DK1373296 T3 DK 1373296T3 DK 02723603 T DK02723603 T DK 02723603T DK 1373296 T3 DK1373296 T3 DK 1373296T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- preparation
- immunogenic response
- proteins
- altered immunogenic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27845901P | 2001-03-23 | 2001-03-23 | |
PCT/US2002/009205 WO2002077187A2 (en) | 2001-03-23 | 2002-03-22 | Proteins producing an altered immunogenic response and methods of making and using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1373296T3 true DK1373296T3 (da) | 2012-01-09 |
Family
ID=23065053
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02723603.3T DK1373296T3 (da) | 2001-03-23 | 2002-03-22 | Proteiner, der frembringer et ændret immunogent respons, og fremgangsmåder til fremstilling og anvendelse deraf |
Country Status (11)
Country | Link |
---|---|
US (3) | US6929939B2 (da) |
EP (1) | EP1373296B1 (da) |
CN (1) | CN100489094C (da) |
AT (1) | ATE527276T1 (da) |
AU (1) | AU2002254374A1 (da) |
CA (1) | CA2441595C (da) |
DK (1) | DK1373296T3 (da) |
HK (1) | HK1061566A1 (da) |
PL (1) | PL210859B1 (da) |
RU (1) | RU2311458C2 (da) |
WO (1) | WO2002077187A2 (da) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA23346A1 (fr) * | 1993-10-14 | 1995-04-01 | Genencor Int | Variantes de la subtilisine |
ES2367505T3 (es) * | 1997-10-23 | 2011-11-04 | Danisco Us Inc. | Variantes de proteasa con sustituciones múltiples con carga neta alterada para usar en detergentes. |
RU2311458C2 (ru) * | 2001-03-23 | 2007-11-27 | Джененкор Интернэшнл, Инк. | Белки, вызывающие измененную иммуногенную реакцию, и способы их получения и использования |
US20030157645A1 (en) * | 2001-12-21 | 2003-08-21 | Direvo Bio Tech Ag. | Subtilisin variants with improved characteristics |
CA2471972A1 (en) * | 2001-12-31 | 2003-07-17 | Genencor International, Inc. | Proteases producing an altered immunological response and methods of making and using the same |
AU2003210552A1 (en) * | 2002-01-16 | 2003-09-02 | Genencor International, Inc. | Multiply-substituted protease variants |
AU2003210551A1 (en) * | 2002-01-16 | 2003-09-02 | Genencor International, Inc. | Multiply-substituted protease variants |
AU2003272517A1 (en) * | 2002-09-13 | 2004-04-30 | Zicam, Llc. | Compositions to reduce congestion and methods for application thereof to the nasal membrane |
US20090010920A1 (en) | 2003-03-03 | 2009-01-08 | Xencor, Inc. | Fc Variants Having Decreased Affinity for FcyRIIb |
US7202202B2 (en) * | 2003-06-27 | 2007-04-10 | The Procter & Gamble Company | Consumable detergent composition for use in a lipophilic fluid |
CN101454452B (zh) * | 2003-08-06 | 2014-01-01 | 马里兰大学生物技术研究所 | 用于亲和纯化的工程蛋白酶及融合蛋白的加工 |
US8883147B2 (en) | 2004-10-21 | 2014-11-11 | Xencor, Inc. | Immunoglobulins insertions, deletions, and substitutions |
US9714282B2 (en) | 2003-09-26 | 2017-07-25 | Xencor, Inc. | Optimized Fc variants and methods for their generation |
US8399618B2 (en) | 2004-10-21 | 2013-03-19 | Xencor, Inc. | Immunoglobulin insertions, deletions, and substitutions |
US8501424B2 (en) * | 2003-11-03 | 2013-08-06 | Danisco Us Inc. | Cd4+ epitopes of bone morphogenetic proteins |
EP1697741A4 (en) | 2003-12-04 | 2008-02-13 | Xencor Inc | PROCESS FOR PRODUCING PROTEIN VARIANTS WITH INCREASED HOST STRUCTURE CONTENT AND COMPOSITIONS THEREOF |
EP1700119B1 (en) * | 2003-12-18 | 2010-02-10 | Genencor International, Inc. | Beta-lactamase cd4+ t-cell epitopes |
US7276585B2 (en) | 2004-03-24 | 2007-10-02 | Xencor, Inc. | Immunoglobulin variants outside the Fc region |
CN1969042B (zh) * | 2004-04-02 | 2014-09-24 | 诺维信公司 | 具有改变的免疫原性的枯草杆菌酶变体 |
US20090060933A1 (en) * | 2004-06-14 | 2009-03-05 | Estell David A | Proteases producing an altered immunogenic response and methods of making and using the same |
SI2471813T1 (sl) | 2004-07-15 | 2015-03-31 | Xencor, Inc. | Optimirane Fc variante |
US8367805B2 (en) | 2004-11-12 | 2013-02-05 | Xencor, Inc. | Fc variants with altered binding to FcRn |
AU2005304624B2 (en) | 2004-11-12 | 2010-10-07 | Xencor, Inc. | Fc variants with altered binding to FcRn |
US8802820B2 (en) | 2004-11-12 | 2014-08-12 | Xencor, Inc. | Fc variants with altered binding to FcRn |
US20090035798A1 (en) * | 2005-04-27 | 2009-02-05 | Harding Fiona A | Methods for Reducing the Immunogenicity of Cytokines and Removal of Cell Surface Markers |
BRPI0611936A2 (pt) * | 2005-06-24 | 2011-02-22 | Solvay Pharm Gmbh | protease, uso de uma protease, composição farmacêutica, e, método para o tratamento de doença |
DK1931709T3 (da) | 2005-10-03 | 2017-03-13 | Xencor Inc | Fc-varianter med optimerede fc-receptorbindingsegenskaber |
EP2078077A2 (en) * | 2006-10-04 | 2009-07-15 | Codon Devices, Inc | Nucleic acid libraries and their design and assembly |
EP4269443A3 (en) | 2007-12-26 | 2023-12-27 | Xencor, Inc. | Fc variants with altered binding to fcrn |
WO2009149218A2 (en) * | 2008-06-03 | 2009-12-10 | Codon Devices, Inc. | Novel proteins and methods of designing and using same |
EP2578680B1 (en) * | 2008-06-06 | 2016-04-27 | Danisco US Inc. | Compositions and methods comprising variant microbial proteases |
EP2216392B1 (en) * | 2009-02-02 | 2013-11-13 | The Procter and Gamble Company | Liquid hand dishwashing detergent composition |
PL2213713T3 (pl) * | 2009-02-02 | 2014-07-31 | Procter & Gamble | Płynna kompozycja środka czyszczącego do ręcznego mycia naczyń |
EP2216391A1 (en) * | 2009-02-02 | 2010-08-11 | The Procter & Gamble Company | Liquid hand dishwashing detergent composition |
CA2751171A1 (en) * | 2009-02-02 | 2010-08-05 | The Procter & Gamble Company | Liquid hand dishwashing detergent composition |
EP2216390B1 (en) * | 2009-02-02 | 2013-11-27 | The Procter and Gamble Company | Hand dishwashing method |
EP3023483A1 (en) * | 2009-02-02 | 2016-05-25 | The Procter and Gamble Company | Liquid hand diswashing detergent composition |
MX2011010040A (es) * | 2009-04-01 | 2011-11-18 | Danisco Us Inc | Sistema de limpieza que comprende una alfa-amilasa y una proteasa. |
US9493578B2 (en) | 2009-09-02 | 2016-11-15 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
AR079338A1 (es) * | 2009-12-09 | 2012-01-18 | Danisco Us Inc | Variantes de proteasa de bacillus y acidos nucleicos que codifican dichas variantes |
PL2558573T3 (pl) * | 2010-04-15 | 2017-08-31 | Danisco Us Inc. | Kompozycje i sposoby obejmujące warianty proteazy |
US20130260438A1 (en) * | 2010-05-06 | 2013-10-03 | Danisco Us Inc. | Compositions and methods comprising serine protease variants (as amended) |
DE102010063458A1 (de) * | 2010-12-17 | 2012-06-21 | Henkel Ag & Co. Kgaa | Lagerstabiles flüssiges Wasch- oder Reinigungsmittel enthaltend Protease und Amylase |
US9039689B2 (en) | 2011-05-11 | 2015-05-26 | Icecure Medical Ltd. | Phase separation of cryogen in cryosurgical instrument |
EP2793944A4 (en) | 2011-12-23 | 2015-09-02 | Nicholas B Lydon | IMMUNOGLOBULINS AND VARIANTS DIRECTED AGAINST PATHOGENIC MICROBES |
US9988439B2 (en) | 2011-12-23 | 2018-06-05 | Nicholas B. Lydon | Immunoglobulins and variants directed against pathogenic microbes |
GB201212934D0 (en) * | 2012-07-20 | 2012-09-05 | Dupont Nutrition Biosci Aps | Method |
Family Cites Families (66)
Publication number | Priority date | Publication date | Assignee | Title |
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US34606A (en) * | 1862-03-04 | Improvement in machines for combing cotton | ||
US3755560A (en) * | 1971-06-30 | 1973-08-28 | Dow Chemical Co | Nongreasy cosmetic lotions |
US3929678A (en) * | 1974-08-01 | 1975-12-30 | Procter & Gamble | Detergent composition having enhanced particulate soil removal performance |
JPS5333919A (en) * | 1976-09-10 | 1978-03-30 | Nippon Steel Corp | Production of cold rolled aluminum killed steel sheet with excellent deep drawability |
JPS51125468A (en) * | 1975-03-27 | 1976-11-01 | Sanyo Chem Ind Ltd | Method of preparing resins of high water absorbency |
US4152416A (en) | 1976-09-17 | 1979-05-01 | Marra Dorothea C | Aerosol antiperspirant compositions delivering astringent salt with low mistiness and dustiness |
NL190101C (nl) * | 1978-11-13 | 1993-11-01 | Givaudan & Cie Sa | Dibenzoylmethaanverbinding en tegen licht beschermend preparaat. |
US4261868A (en) * | 1979-08-08 | 1981-04-14 | Lever Brothers Company | Stabilized enzymatic liquid detergent composition containing a polyalkanolamine and a boron compound |
US4404128A (en) * | 1981-05-29 | 1983-09-13 | The Procter & Gamble Company | Enzyme detergent composition |
US4421769A (en) * | 1981-09-29 | 1983-12-20 | The Procter & Gamble Company | Skin conditioning composition |
JPS58144105A (ja) * | 1982-02-12 | 1983-08-27 | Kurabo Ind Ltd | スケ−ル除去獣毛繊維の製法 |
IE81141B1 (en) | 1983-06-24 | 2000-04-05 | Genencor Int | Procaryotic carbonyl hydrolases |
US4760025A (en) * | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
US5204015A (en) * | 1984-05-29 | 1993-04-20 | Genencor International, Inc. | Subtilisin mutants |
US5264366A (en) | 1984-05-29 | 1993-11-23 | Genencor, Inc. | Protease deficient bacillus |
US5185258A (en) * | 1984-05-29 | 1993-02-09 | Genencor International, Inc. | Subtilisin mutants |
US4663157A (en) * | 1985-02-28 | 1987-05-05 | The Proctor & Gamble Company | Sunscreen compositions |
EP0209071B2 (de) * | 1985-07-10 | 1998-07-15 | Novartis AG | Kontaktlinsenpflegesatz |
US4990452A (en) * | 1986-02-12 | 1991-02-05 | Genex Corporation | Combining mutations for stabilization of subtilisin |
EP0251446B1 (en) | 1986-04-30 | 1994-12-28 | Genencor International, Inc. | Non-human Carbonyl hydrolase mutants, DNA sequences and vectors encoding same and hosts transformed with said vectors |
US4937370A (en) * | 1987-06-02 | 1990-06-26 | The Procter & Gamble Company | Novel chromophores, sunscreen compositions and methods for preventing sunburn |
US4999186A (en) * | 1986-06-27 | 1991-03-12 | The Procter & Gamble Company | Novel sunscreen agents, sunscreen compositions and methods for preventing sunburn |
US4914031A (en) * | 1987-04-10 | 1990-04-03 | Amgen, Inc. | Subtilisin analogs |
EP0496433B1 (en) * | 1987-10-22 | 1999-03-24 | The Procter & Gamble Company | Photoprotection compositions comprising chelating agents |
DK6488D0 (da) | 1988-01-07 | 1988-01-07 | Novo Industri As | Enzymer |
US5116741A (en) * | 1988-04-12 | 1992-05-26 | Genex Corporation | Biosynthetic uses of thermostable proteases |
US5087372A (en) * | 1989-03-24 | 1992-02-11 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for removing heavy metal ions from contaminated water and a porous membrane usable therefor |
AU618675B2 (en) * | 1989-05-17 | 1992-01-02 | Amgen, Inc. | Multiply mutated subtilisins |
US5665587A (en) * | 1989-06-26 | 1997-09-09 | Novo Nordisk A/S | Modified subtilisins and detergent compositions containing same |
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US5264365A (en) * | 1990-11-09 | 1993-11-23 | Board Of Regents, The University Of Texas System | Protease-deficient bacterial strains for production of proteolytically sensitive polypeptides |
US5073372A (en) | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
US5073371A (en) * | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
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DK132892D0 (da) | 1992-10-30 | 1992-10-30 | Novo Nordisk As | Proteiner |
MA23346A1 (fr) * | 1993-10-14 | 1995-04-01 | Genencor Int | Variantes de la subtilisine |
CZ105296A3 (en) * | 1993-10-14 | 1996-09-11 | Procter & Gamble | Bleaching agent containing protease enzymes, cleansing agents, agent for cleaning fabrics and fabric cleaning method |
US5679630A (en) * | 1993-10-14 | 1997-10-21 | The Procter & Gamble Company | Protease-containing cleaning compositions |
FR2712286B1 (fr) * | 1993-11-12 | 1995-12-22 | Oreal | Nouveaux N-mercaptoalkyl alcanediamines et leur utilisation. |
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FR2719481B1 (fr) | 1994-05-05 | 1996-05-31 | Oreal | Composition à base de composés antifongiques et de composés antibactériens halogènes pour diminuer la chute des cheveux. |
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GB9415421D0 (en) | 1994-07-30 | 1994-09-21 | Procter & Gamble | Cosmetic compositions and processes for manufacture thereof |
MX9703895A (es) | 1994-11-28 | 1997-08-30 | Procter & Gamble | Composiciones topicas para el cuidado de la piel que contienen esteres de acido carboxilico de poliol espesado como agentes de acondicionamiento de la piel. |
MX9704137A (es) | 1994-12-07 | 1997-09-30 | Novo Nordisk As | Polipeptidos de alergenicidad reducida. |
WO1996040791A1 (en) | 1995-06-07 | 1996-12-19 | Novo Nordisk A/S | Modification of polypeptides |
EP0894128A1 (en) | 1996-02-15 | 1999-02-03 | Novo Nordisk A/S | Conjugation of polypeptides |
US5627508A (en) * | 1996-05-10 | 1997-05-06 | The United States Of America As Represented By The Secretary Of The Navy | Pilot vehicle which is useful for monitoring hazardous conditions on railroad tracks |
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US5966485A (en) * | 1996-11-22 | 1999-10-12 | Siecor Corporation | Method of producing core protrusion relative to cladding in an optical fiber of a fiber optic connector |
CA2272306A1 (en) | 1996-11-22 | 1998-05-28 | The Procter & Gamble Company | Cosmetic compositions |
MA25044A1 (fr) * | 1997-10-23 | 2000-10-01 | Procter & Gamble | Compositions de lavage contenant des variants de proteases multisubstituees. |
EP1082442A1 (en) | 1998-03-26 | 2001-03-14 | The Procter & Gamble Company | Serine protease variants having amino acid substitutions |
US6835550B1 (en) * | 1998-04-15 | 2004-12-28 | Genencor International, Inc. | Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins |
US6642011B2 (en) * | 1998-04-15 | 2003-11-04 | Genencor International, Inc. | Human protease and use of such protease for pharmaceutical applications and for reducing the allergenicity of non-human proteins |
US5935556A (en) | 1998-07-30 | 1999-08-10 | The Procter & Gamble Company | Sunscreen compositions |
US5989528A (en) | 1998-07-30 | 1999-11-23 | The Procter & Gamble Company | Sunscreen compositions |
US5972316A (en) * | 1998-10-16 | 1999-10-26 | The Procter & Gamble Company | UV protection compositions |
US5968485A (en) | 1998-10-16 | 1999-10-19 | The Procter & Gamble Company | UV protection compositions |
AU1275599A (en) | 1998-10-23 | 2000-05-15 | Procter & Gamble Company, The | Skin care compositions |
CN1399677A (zh) * | 1999-07-22 | 2003-02-26 | 宝洁公司 | 在确定表位区有氨基酸取代的枯草杆菌蛋白酶变体 |
US6428799B1 (en) * | 1999-08-02 | 2002-08-06 | The Procter & Gamble Company | Personal care articles |
US6815865B2 (en) | 2000-01-31 | 2004-11-09 | Seralco Microtechnology Ltd. | Switching arrangement for a radiation guide |
US20030170846A1 (en) * | 2000-04-24 | 2003-09-11 | Weisgerber David John | Enzyme variants having one or more D-amino acid substitutions |
ATE504205T1 (de) | 2000-10-02 | 2011-04-15 | Danisco Us Inc | Methode zur bestimmung der immunogenität von proteinen, die eine veränderte immunantwort hervorrufen |
RU2311458C2 (ru) * | 2001-03-23 | 2007-11-27 | Джененкор Интернэшнл, Инк. | Белки, вызывающие измененную иммуногенную реакцию, и способы их получения и использования |
-
2002
- 2002-03-22 RU RU2003131177/13A patent/RU2311458C2/ru not_active IP Right Cessation
- 2002-03-22 CN CNB028070836A patent/CN100489094C/zh not_active Expired - Fee Related
- 2002-03-22 AU AU2002254374A patent/AU2002254374A1/en not_active Abandoned
- 2002-03-22 PL PL364138A patent/PL210859B1/pl unknown
- 2002-03-22 AT AT02723603T patent/ATE527276T1/de not_active IP Right Cessation
- 2002-03-22 WO PCT/US2002/009205 patent/WO2002077187A2/en not_active Application Discontinuation
- 2002-03-22 CA CA2441595A patent/CA2441595C/en not_active Expired - Fee Related
- 2002-03-22 US US10/104,693 patent/US6929939B2/en not_active Expired - Lifetime
- 2002-03-22 EP EP02723603A patent/EP1373296B1/en not_active Expired - Lifetime
- 2002-03-22 DK DK02723603.3T patent/DK1373296T3/da active
-
2004
- 2004-06-23 HK HK04104503.8A patent/HK1061566A1/xx not_active IP Right Cessation
-
2005
- 2005-05-12 US US11/127,727 patent/US20050202551A1/en not_active Abandoned
- 2005-05-12 US US11/127,947 patent/US7476528B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2441595A1 (en) | 2002-10-03 |
US7476528B2 (en) | 2009-01-13 |
EP1373296A4 (en) | 2007-03-28 |
AU2002254374A1 (en) | 2002-10-08 |
WO2002077187A3 (en) | 2003-04-24 |
EP1373296B1 (en) | 2011-10-05 |
US20050202552A1 (en) | 2005-09-15 |
CA2441595C (en) | 2012-07-03 |
EP1373296A2 (en) | 2004-01-02 |
WO2002077187A2 (en) | 2002-10-03 |
RU2311458C2 (ru) | 2007-11-27 |
CN100489094C (zh) | 2009-05-20 |
US20050202551A1 (en) | 2005-09-15 |
PL364138A1 (en) | 2004-12-13 |
PL210859B1 (pl) | 2012-03-30 |
CN1512998A (zh) | 2004-07-14 |
US6929939B2 (en) | 2005-08-16 |
HK1061566A1 (en) | 2004-09-24 |
RU2003131177A (ru) | 2005-01-20 |
US20030118605A1 (en) | 2003-06-26 |
ATE527276T1 (de) | 2011-10-15 |
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