AT500848B1 - Humanisierte anti-erbb2-antikörper - Google Patents

Humanisierte anti-erbb2-antikörper Download PDF

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Publication number
AT500848B1
AT500848B1 AT0911000A AT91102000A AT500848B1 AT 500848 B1 AT500848 B1 AT 500848B1 AT 0911000 A AT0911000 A AT 0911000A AT 91102000 A AT91102000 A AT 91102000A AT 500848 B1 AT500848 B1 AT 500848B1
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AT
Austria
Prior art keywords
antibody
erbb2
cancer
quot
cells
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Application number
AT0911000A
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German (de)
English (en)
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AT500848A1 (de
Original Assignee
Genentech Inc
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22495168&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT500848(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of AT500848A1 publication Critical patent/AT500848A1/de
Application granted granted Critical
Publication of AT500848B1 publication Critical patent/AT500848B1/de

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
AT0911000A 1999-06-25 2000-06-23 Humanisierte anti-erbb2-antikörper AT500848B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14131699P 1999-06-25 1999-06-25
PCT/US2000/017366 WO2001000245A2 (en) 1999-06-25 2000-06-23 HUMANIZED ANTI-ErbB2 ANTIBODIES AND TREATMENT WITH ANTI-ErbB2 ANTIBODIES

Publications (2)

Publication Number Publication Date
AT500848A1 AT500848A1 (de) 2006-04-15
AT500848B1 true AT500848B1 (de) 2008-01-15

Family

ID=22495168

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0911000A AT500848B1 (de) 1999-06-25 2000-06-23 Humanisierte anti-erbb2-antikörper
AT00943115T ATE437655T1 (de) 1999-06-25 2000-06-23 Humanisierte anti-erbb2 antikörper und behandlung mit anti-erbb2 antikörper

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT00943115T ATE437655T1 (de) 1999-06-25 2000-06-23 Humanisierte anti-erbb2 antikörper und behandlung mit anti-erbb2 antikörper

Country Status (32)

Country Link
EP (2) EP2112167A3 (cg-RX-API-DMAC7.html)
JP (2) JP4283474B2 (cg-RX-API-DMAC7.html)
KR (2) KR100850389B1 (cg-RX-API-DMAC7.html)
CN (4) CN101518653B (cg-RX-API-DMAC7.html)
AR (1) AR024464A1 (cg-RX-API-DMAC7.html)
AT (2) AT500848B1 (cg-RX-API-DMAC7.html)
AU (2) AU784045B2 (cg-RX-API-DMAC7.html)
BE (1) BE2013C020I2 (cg-RX-API-DMAC7.html)
BR (2) BRPI0012198B8 (cg-RX-API-DMAC7.html)
CA (2) CA2376596C (cg-RX-API-DMAC7.html)
CH (1) CH694589A5 (cg-RX-API-DMAC7.html)
CY (2) CY1109525T1 (cg-RX-API-DMAC7.html)
CZ (1) CZ299702B6 (cg-RX-API-DMAC7.html)
DE (2) DE60042648D1 (cg-RX-API-DMAC7.html)
DK (1) DK1189641T5 (cg-RX-API-DMAC7.html)
ES (1) ES2329437T3 (cg-RX-API-DMAC7.html)
FR (1) FR13C0016I2 (cg-RX-API-DMAC7.html)
GB (1) GB2368796B (cg-RX-API-DMAC7.html)
GE (1) GEP20104998B (cg-RX-API-DMAC7.html)
HU (1) HU226742B1 (cg-RX-API-DMAC7.html)
IL (3) IL146954A0 (cg-RX-API-DMAC7.html)
LU (1) LU92164I2 (cg-RX-API-DMAC7.html)
MX (1) MXPA01013458A (cg-RX-API-DMAC7.html)
NO (3) NO328377B1 (cg-RX-API-DMAC7.html)
NZ (2) NZ531426A (cg-RX-API-DMAC7.html)
PL (2) PL204629B1 (cg-RX-API-DMAC7.html)
PT (1) PT1189641E (cg-RX-API-DMAC7.html)
RU (2) RU2270029C2 (cg-RX-API-DMAC7.html)
SI (3) SI2283866T1 (cg-RX-API-DMAC7.html)
TR (1) TR200103756T2 (cg-RX-API-DMAC7.html)
WO (1) WO2001000245A2 (cg-RX-API-DMAC7.html)
ZA (2) ZA200109786B (cg-RX-API-DMAC7.html)

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