AR054283A1 - Formulacion que comprende un compuesto de tienopiridina , su uso para preparar un medicamento, metodo para mejorar la estabilidad y vida de anaquel de dicho compuesto, metodo para minimizar impurezas en la formulacion proceso para la manufactura de dicha formulacion envasada, articulo de manufactura - Google Patents
Formulacion que comprende un compuesto de tienopiridina , su uso para preparar un medicamento, metodo para mejorar la estabilidad y vida de anaquel de dicho compuesto, metodo para minimizar impurezas en la formulacion proceso para la manufactura de dicha formulacion envasada, articulo de manufacturaInfo
- Publication number
- AR054283A1 AR054283A1 AR20060102430A ARP060102430A AR054283A1 AR 054283 A1 AR054283 A1 AR 054283A1 AR 20060102430 A AR20060102430 A AR 20060102430A AR P060102430 A ARP060102430 A AR P060102430A AR 054283 A1 AR054283 A1 AR 054283A1
- Authority
- AR
- Argentina
- Prior art keywords
- formulation
- compound
- manufacture
- tienopiridine
- anaquel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Formulacion que comprende una cantidad terapéuticamente efectiva de 5 mg hasta 60 mg de equivalente base del compuesto de tienopiridina de formula (1) envasado en forma de tabletas, comprimidos ovalados o cápsulas, en un paquete de burbuja de gas inerte, tal como nitrogeno, argon, neon, dioxido o monoxido de C, impermeable al aire y humedad, que puede ser de lámina e aluminio. Métodos para mejorar la estabilidad, minimizar las impurezas y para la manufactura de un medicamento que la comprenden. Proceso para manufactura de una formulacion envasada y artículo de manufactura correspondientes. Método para preparar un medicamento comprendiendo dicho compuesto de formula (1) que es util para el tratamiento y/o prevencion de trombosis, síndrome coronario agudo, ACS-MM, apoplejía, aneurismas cerebro vasculares y enfermedades vasculares de alto riesgo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68918305P | 2005-06-10 | 2005-06-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR054283A1 true AR054283A1 (es) | 2007-06-13 |
Family
ID=37198935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR20060102430A AR054283A1 (es) | 2005-06-10 | 2006-06-09 | Formulacion que comprende un compuesto de tienopiridina , su uso para preparar un medicamento, metodo para mejorar la estabilidad y vida de anaquel de dicho compuesto, metodo para minimizar impurezas en la formulacion proceso para la manufactura de dicha formulacion envasada, articulo de manufactura |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US20080176893A1 (es) |
| EP (1) | EP1896019B1 (es) |
| JP (1) | JP2008543755A (es) |
| KR (2) | KR20080008413A (es) |
| CN (1) | CN101193633B (es) |
| AR (1) | AR054283A1 (es) |
| AT (1) | ATE441413T1 (es) |
| AU (1) | AU2006258102B2 (es) |
| BR (1) | BRPI0611350B8 (es) |
| CA (1) | CA2611668C (es) |
| CY (1) | CY1109502T1 (es) |
| DE (1) | DE602006008942D1 (es) |
| DK (1) | DK1896019T3 (es) |
| DO (1) | DOP2006000126A (es) |
| EA (1) | EA011693B1 (es) |
| EC (1) | ECSP077984A (es) |
| ES (1) | ES2330373T3 (es) |
| HK (1) | HK1116422A1 (es) |
| HR (1) | HRP20090516T1 (es) |
| IL (1) | IL187830A0 (es) |
| MA (1) | MA29688B1 (es) |
| MX (1) | MX2007015431A (es) |
| MY (1) | MY151038A (es) |
| NO (1) | NO20076317L (es) |
| NZ (1) | NZ564003A (es) |
| PE (1) | PE20070320A1 (es) |
| PL (1) | PL1896019T3 (es) |
| PT (1) | PT1896019E (es) |
| RS (1) | RS51194B (es) |
| SI (1) | SI1896019T1 (es) |
| TN (1) | TNSN07466A1 (es) |
| TW (1) | TWI318571B (es) |
| UA (1) | UA91051C2 (es) |
| WO (1) | WO2006135605A2 (es) |
| ZA (1) | ZA200710697B (es) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2672157C (en) * | 2006-12-07 | 2016-07-26 | Daiichi Sankyo Company, Limited | Method for producing solid preparation |
| JP5289975B2 (ja) * | 2006-12-07 | 2013-09-11 | 第一三共株式会社 | マンニトール又は乳糖を含有する固形製剤 |
| BRPI0719395C1 (pt) * | 2006-12-07 | 2021-05-25 | Daiichi Sankyo Co Ltd | tablete revestido de filme |
| KR101647842B1 (ko) * | 2006-12-07 | 2016-08-11 | 다이이찌 산쿄 가부시키가이샤 | 저장 안정성이 개선된 의약 조성물 |
| BRPI0720248A2 (pt) * | 2006-12-07 | 2013-12-31 | Lilly Co Eli | Artigo de fabricação de prasugrel |
| JP5274261B2 (ja) * | 2006-12-07 | 2013-08-28 | 第一三共株式会社 | 低置換度ヒドロキシプロピルセルロースを含有する医薬組成物 |
| CN101675058A (zh) * | 2007-03-02 | 2010-03-17 | 第一三共株式会社 | 用于制备高纯度普拉格雷盐酸盐的方法 |
| DK2152078T3 (da) | 2007-04-27 | 2021-02-08 | Cydex Pharmaceuticals Inc | Formuleringer indeholdende clopidogrel og sulfoalkylethercyclodextrin og anvendelsesfremgangsmåder |
| GB2450117A (en) * | 2007-06-13 | 2008-12-17 | Reckitt Benckiser Healthcare | A water- and oxygen-occlusive blister tablet pack |
| US20110003847A1 (en) * | 2008-02-06 | 2011-01-06 | Helm Ag | Prasugrel Salts with Improved Properties |
| EP2107061A1 (en) * | 2008-04-02 | 2009-10-07 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of optically enriched clopidogrel |
| PL2112155T3 (pl) | 2008-04-25 | 2011-03-31 | Sandoz Ag | Wodorosiarczan (VI) 2-acetoksy-5-(α-cyklopropylokarbonylo-2-fluorobenzylo)-4,5,6,7-tetrahydrotieno[3,2-c]pirydyny i sposób jego otrzymywania |
| SI2398468T1 (sl) * | 2009-02-17 | 2017-03-31 | Krka, D.D., Novo Mesto | Farmacevtske sestave, ki obsegajo prasugrel ali njegove farmacevtsko sprejemljive kislinske adicijske soli in postopek za njihovo pripravo |
| ES2769949T3 (es) | 2009-05-13 | 2020-06-29 | Cydex Pharmaceuticals Inc | Composiciones farmacéuticas que comprenden prasugrel y derivados de ciclodextrina y métodos de preparación y uso de las mismas |
| DE102009036646A1 (de) | 2009-08-07 | 2011-02-10 | Ratiopharm Gmbh | Prasugrel in nicht-kristalliner Form und pharmazeutische Zusammensetzung davon |
| JP2013032289A (ja) * | 2009-10-28 | 2013-02-14 | Daiichi Sankyo Co Ltd | ワックス安定製剤 |
| WO2011052499A1 (ja) * | 2009-10-28 | 2011-05-05 | 第一三共株式会社 | 貯蔵安定性が改善された医薬組成物 |
| WO2011092720A2 (en) * | 2010-02-01 | 2011-08-04 | Msn Laboratories Limited | Pharmaceutical composition of prasugrel and its pharmaceutically acceptable salts |
| EP2409685A3 (en) | 2010-07-19 | 2012-02-01 | Sanovel Ilac Sanayi ve Ticaret A.S. | Orally-disintegrating formulations of prasugrel |
| TR201006802A1 (tr) * | 2010-08-17 | 2012-03-21 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Prasugrelin oral yolla dağılan formülasyonları. |
| TR201007926A1 (tr) | 2010-07-19 | 2012-02-21 | Sanovel İlaç San.Ve Ti̇c.A.Ş. | Prasugrel tablet formülasyonları. |
| TR201005900A1 (tr) | 2010-07-19 | 2012-02-21 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Geliştirilmiş stabiliteye sahip prasugrel granülleri. |
| CZ2011872A3 (cs) | 2011-12-22 | 2013-07-03 | Zentiva, K.S. | Farmaceutická formulace prasugrelu hydrobromidu |
| US8603537B2 (en) | 2012-04-02 | 2013-12-10 | Egis Pharmaceuticals Plc | Prasugrel containing quickly released stable oral pharmaceutical compositions |
| EP2722036A1 (en) | 2012-10-19 | 2014-04-23 | Sanovel Ilac Sanayi ve Ticaret A.S. | Solid oral formulations of prasugrel |
| EP2722037A1 (en) | 2012-10-19 | 2014-04-23 | Sanovel Ilac Sanayi ve Ticaret A.S. | Prasugrel formulations |
| CN102993210A (zh) * | 2012-12-19 | 2013-03-27 | 苏春华 | 一种吡啶并噻吩的新化合物 |
| EP2979693A1 (en) | 2014-08-01 | 2016-02-03 | Zaklady Farmaceutyczne Polpharma SA | Pharmaceutical composition comprising prasugrel or pharmaceutically acceptable salt thereof and process for its preparation |
| WO2016122421A1 (en) | 2015-01-29 | 2016-08-04 | Pharmactive Ilaç Sanayi Ve Ticaret A.Ş. | Stable pharmaceutical compositions containing prasugrel base |
| EP3158993A1 (en) | 2015-10-22 | 2017-04-26 | Zaklady Farmaceutyczne Polpharma SA | Process for preparing a tablet comprising prasugrel or pharmaceutically acceptable salt thereof |
| CN107304216A (zh) * | 2016-04-20 | 2017-10-31 | 陕西合成药业股份有限公司 | 噻吩吡啶类衍生物及其制备方法和用途 |
| HU231079B1 (hu) | 2016-06-23 | 2020-06-29 | Richter Gedeon Nyrt. | Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával |
| GR1009230B (el) | 2016-10-12 | 2018-02-22 | Φαρματεν Αβεε | Φαρμακευτικο σκευασμα που περιλαμβανει βεσυλικη πρασουγρελη |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI101150B (fi) * | 1991-09-09 | 1998-04-30 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi |
| JP4001199B2 (ja) * | 2000-07-06 | 2007-10-31 | 第一三共株式会社 | ヒドロピリジン誘導体酸付加塩 |
| PT1728794E (pt) * | 2000-07-06 | 2008-07-15 | Ube Industries | Sal de adição maleato de derivados de hidropiridina |
| EP1243524A3 (en) * | 2001-03-16 | 2004-04-07 | Pfizer Products Inc. | Pharmaceutical kit for oxygen-sensitive drugs |
| JP4394873B2 (ja) * | 2001-12-19 | 2010-01-06 | 武田薬品工業株式会社 | 酸素に不安定な化合物を含有する固形組成物およびその安定化方法 |
| SI21302A (sl) * | 2002-10-11 | 2004-04-30 | LEK farmacevtska dru�ba d.d. | Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino |
| US20050020554A1 (en) * | 2003-06-06 | 2005-01-27 | Ahmed Salah U. | Stability of hormone formulations |
| SK50462005A3 (sk) * | 2003-08-05 | 2005-09-08 | Zentiva, A. S. | Spôsoby stabilizácie atorvastatínu |
-
2006
- 2006-06-02 TW TW095119687A patent/TWI318571B/zh active
- 2006-06-06 AU AU2006258102A patent/AU2006258102B2/en not_active Ceased
- 2006-06-06 MX MX2007015431A patent/MX2007015431A/es active IP Right Grant
- 2006-06-06 KR KR1020077028749A patent/KR20080008413A/ko not_active Application Discontinuation
- 2006-06-06 PL PL06772240T patent/PL1896019T3/pl unknown
- 2006-06-06 SI SI200630490T patent/SI1896019T1/sl unknown
- 2006-06-06 DK DK06772240T patent/DK1896019T3/da active
- 2006-06-06 RS RSP-2009/0425A patent/RS51194B/sr unknown
- 2006-06-06 CA CA2611668A patent/CA2611668C/en not_active Expired - Fee Related
- 2006-06-06 NZ NZ564003A patent/NZ564003A/en not_active IP Right Cessation
- 2006-06-06 ES ES06772240T patent/ES2330373T3/es active Active
- 2006-06-06 KR KR1020107011742A patent/KR20100076050A/ko not_active Application Discontinuation
- 2006-06-06 DO DO2006000126A patent/DOP2006000126A/es unknown
- 2006-06-06 CN CN2006800205289A patent/CN101193633B/zh active Active
- 2006-06-06 US US11/913,889 patent/US20080176893A1/en not_active Abandoned
- 2006-06-06 UA UAA200712993A patent/UA91051C2/ru unknown
- 2006-06-06 AT AT06772240T patent/ATE441413T1/de active
- 2006-06-06 BR BRPI0611350A patent/BRPI0611350B8/pt active IP Right Grant
- 2006-06-06 PT PT06772240T patent/PT1896019E/pt unknown
- 2006-06-06 DE DE602006008942T patent/DE602006008942D1/de active Active
- 2006-06-06 WO PCT/US2006/021860 patent/WO2006135605A2/en active Application Filing
- 2006-06-06 JP JP2008515813A patent/JP2008543755A/ja active Pending
- 2006-06-06 EP EP06772240A patent/EP1896019B1/en not_active Revoked
- 2006-06-06 EA EA200702670A patent/EA011693B1/ru not_active IP Right Cessation
- 2006-06-08 PE PE2006000641A patent/PE20070320A1/es not_active Application Discontinuation
- 2006-06-09 MY MYPI20062708 patent/MY151038A/en unknown
- 2006-06-09 AR AR20060102430A patent/AR054283A1/es unknown
-
2007
- 2007-12-03 IL IL187830A patent/IL187830A0/en unknown
- 2007-12-07 EC EC2007007984A patent/ECSP077984A/es unknown
- 2007-12-07 TN TNP2007000466A patent/TNSN07466A1/en unknown
- 2007-12-07 ZA ZA200710697A patent/ZA200710697B/xx unknown
- 2007-12-07 NO NO20076317A patent/NO20076317L/no not_active Application Discontinuation
-
2008
- 2008-01-09 MA MA30568A patent/MA29688B1/fr unknown
- 2008-06-20 HK HK08106909.9A patent/HK1116422A1/xx not_active IP Right Cessation
-
2009
- 2009-09-25 HR HR20090516T patent/HRP20090516T1/xx unknown
- 2009-10-22 CY CY20091101101T patent/CY1109502T1/el unknown
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| Date | Code | Title | Description |
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| FB | Suspension of granting procedure |