ATE441413T1 - Formulierung eines thienopyridin- thrombozytenaggregationshemmers - Google Patents

Formulierung eines thienopyridin- thrombozytenaggregationshemmers

Info

Publication number
ATE441413T1
ATE441413T1 AT06772240T AT06772240T ATE441413T1 AT E441413 T1 ATE441413 T1 AT E441413T1 AT 06772240 T AT06772240 T AT 06772240T AT 06772240 T AT06772240 T AT 06772240T AT E441413 T1 ATE441413 T1 AT E441413T1
Authority
AT
Austria
Prior art keywords
thienopyridine
formulation
aggregation inhibitor
thrombocyte aggregation
thrombocyte
Prior art date
Application number
AT06772240T
Other languages
English (en)
Inventor
David Dziennik
Tamara Edelman
Peter Oren
Robert Ternik
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37198935&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE441413(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE441413T1 publication Critical patent/ATE441413T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
AT06772240T 2005-06-10 2006-06-06 Formulierung eines thienopyridin- thrombozytenaggregationshemmers ATE441413T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68918305P 2005-06-10 2005-06-10
PCT/US2006/021860 WO2006135605A2 (en) 2005-06-10 2006-06-06 Formulation of a thienopyridine platelet aggregation inhibitor

Publications (1)

Publication Number Publication Date
ATE441413T1 true ATE441413T1 (de) 2009-09-15

Family

ID=37198935

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06772240T ATE441413T1 (de) 2005-06-10 2006-06-06 Formulierung eines thienopyridin- thrombozytenaggregationshemmers

Country Status (35)

Country Link
US (1) US20080176893A1 (de)
EP (1) EP1896019B1 (de)
JP (1) JP2008543755A (de)
KR (2) KR20080008413A (de)
CN (1) CN101193633B (de)
AR (1) AR054283A1 (de)
AT (1) ATE441413T1 (de)
AU (1) AU2006258102B2 (de)
BR (1) BRPI0611350B8 (de)
CA (1) CA2611668C (de)
CY (1) CY1109502T1 (de)
DE (1) DE602006008942D1 (de)
DK (1) DK1896019T3 (de)
DO (1) DOP2006000126A (de)
EA (1) EA011693B1 (de)
EC (1) ECSP077984A (de)
ES (1) ES2330373T3 (de)
HK (1) HK1116422A1 (de)
HR (1) HRP20090516T1 (de)
IL (1) IL187830A0 (de)
MA (1) MA29688B1 (de)
MX (1) MX2007015431A (de)
MY (1) MY151038A (de)
NO (1) NO20076317L (de)
NZ (1) NZ564003A (de)
PE (1) PE20070320A1 (de)
PL (1) PL1896019T3 (de)
PT (1) PT1896019E (de)
RS (1) RS51194B (de)
SI (1) SI1896019T1 (de)
TN (1) TNSN07466A1 (de)
TW (1) TWI318571B (de)
UA (1) UA91051C2 (de)
WO (1) WO2006135605A2 (de)
ZA (1) ZA200710697B (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
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EP2101767A2 (de) * 2006-12-07 2009-09-23 Eli Lilly & Company Artikel mit prasugrel
TWI488657B (zh) * 2006-12-07 2015-06-21 Daiichi Sankyo Co Ltd 貯藏安定性經改善之醫藥組成物及改善醫藥組成物之貯藏安定性的方法
WO2008069262A1 (ja) * 2006-12-07 2008-06-12 Daiichi Sankyo Company, Limited 安定性が改善されたフィルムコーティング製剤
EP2100608A4 (de) * 2006-12-07 2009-12-09 Daiichi Sankyo Co Ltd Verfahren zur herstellung einer festen zubereitung
BRPI0719393B8 (pt) * 2006-12-07 2021-05-25 Daiichi Sankyo Co Ltd composição farmacêutica
US20100004279A1 (en) * 2006-12-07 2010-01-07 Tomoyuki Watanabe Solid medicinal preparation containing mannitol or lactose
SI2123656T1 (sl) * 2007-03-02 2014-09-30 Daiichi Sankyo Company, Limited Postopek izdelave hidroklorid prasugrela visoke ÄŤistosti
EP3766493B1 (de) 2007-04-27 2023-08-23 CyDex Pharmaceuticals, Inc. Methode zur stabilisierung von clopidogrel unter verwendung von sulfoalkylethercyclodextrin
GB2450117A (en) * 2007-06-13 2008-12-17 Reckitt Benckiser Healthcare A water- and oxygen-occlusive blister tablet pack
DE112009000268T5 (de) 2008-02-06 2011-06-01 Helm Ag Prasugrel-Salze mit verbesserten Eigenschaften
EP2107061A1 (de) * 2008-04-02 2009-10-07 Krka Tovarna Zdravil, D.D., Novo Mesto Herstellungsverfahren für optisch angereichertes Clopidogrel
DE602008002820D1 (de) * 2008-04-25 2010-11-11 Sandoz Ag Hydrogensulfat von 2-Acetoxy-5-(a-cyclopropylcarbonyl-2-fluorbenzyl)-4,5,6,7-tetrahydrothienoÄ3,2-cÜpyridin und dessen Zubereitung
SI2398468T1 (sl) * 2009-02-17 2017-03-31 Krka, D.D., Novo Mesto Farmacevtske sestave, ki obsegajo prasugrel ali njegove farmacevtsko sprejemljive kislinske adicijske soli in postopek za njihovo pripravo
JP5808739B2 (ja) * 2009-05-13 2015-11-10 サイデックス・ファーマシューティカルズ・インコーポレイテッド プラスグレル及びシクロデキストリン誘導体を含む医薬組成物並びにその製造方法及び使用方法
DE102009036646A1 (de) 2009-08-07 2011-02-10 Ratiopharm Gmbh Prasugrel in nicht-kristalliner Form und pharmazeutische Zusammensetzung davon
WO2011052499A1 (ja) * 2009-10-28 2011-05-05 第一三共株式会社 貯蔵安定性が改善された医薬組成物
JP2013032289A (ja) * 2009-10-28 2013-02-14 Daiichi Sankyo Co Ltd ワックス安定製剤
WO2011092720A2 (en) * 2010-02-01 2011-08-04 Msn Laboratories Limited Pharmaceutical composition of prasugrel and its pharmaceutically acceptable salts
TR201005900A1 (tr) 2010-07-19 2012-02-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Geliştirilmiş stabiliteye sahip prasugrel granülleri.
TR201007926A1 (tr) 2010-07-19 2012-02-21 Sanovel İlaç San.Ve Ti̇c.A.Ş. Prasugrel tablet formülasyonları.
EP2409685A3 (de) 2010-07-19 2012-02-01 Sanovel Ilac Sanayi ve Ticaret A.S. Sich im Mund auflösende Formulierungen aus Prasugrel
TR201006802A1 (tr) * 2010-08-17 2012-03-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Prasugrelin oral yolla dağılan formülasyonları.
CZ2011872A3 (cs) 2011-12-22 2013-07-03 Zentiva, K.S. Farmaceutická formulace prasugrelu hydrobromidu
US8603537B2 (en) 2012-04-02 2013-12-10 Egis Pharmaceuticals Plc Prasugrel containing quickly released stable oral pharmaceutical compositions
EP2722037A1 (de) 2012-10-19 2014-04-23 Sanovel Ilac Sanayi ve Ticaret A.S. Prasugrelformulierungen
EP2722036A1 (de) 2012-10-19 2014-04-23 Sanovel Ilac Sanayi ve Ticaret A.S. Feste orale Formulierungen aus Prasugrel
CN102993210A (zh) * 2012-12-19 2013-03-27 苏春华 一种吡啶并噻吩的新化合物
EP2979693A1 (de) 2014-08-01 2016-02-03 Zaklady Farmaceutyczne Polpharma SA Pharmazeutische zusammensetzung mit prasugrel oder pharmazeutisch verträglichem salz davon und verfahren zu deren herstellung
WO2016122421A1 (en) 2015-01-29 2016-08-04 Pharmactive Ilaç Sanayi Ve Ticaret A.Ş. Stable pharmaceutical compositions containing prasugrel base
EP3158993A1 (de) 2015-10-22 2017-04-26 Zaklady Farmaceutyczne Polpharma SA Verfahren zur herstellung einer tablette mit prasugrel oder pharmazeutisch unbedenklichem salz davon
CN107304216A (zh) * 2016-04-20 2017-10-31 陕西合成药业股份有限公司 噻吩吡啶类衍生物及其制备方法和用途
HU231079B1 (hu) 2016-06-23 2020-06-29 Richter Gedeon Nyrt. Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával
GR1009230B (el) 2016-10-12 2018-02-22 Φαρματεν Αβεε Φαρμακευτικο σκευασμα που περιλαμβανει βεσυλικη πρασουγρελη

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101150B (fi) * 1991-09-09 1998-04-30 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
HU230762B1 (hu) * 2000-07-06 2018-03-28 Daiichi Sankyo Company, Limited Hidropiridin-származékok maleát addíciós sója
JP4001199B2 (ja) * 2000-07-06 2007-10-31 第一三共株式会社 ヒドロピリジン誘導体酸付加塩
EP1243524A3 (de) * 2001-03-16 2004-04-07 Pfizer Products Inc. Pharmazeutisches Kit fÜr sauerstoffempfindliche Medikamente
JP4394873B2 (ja) * 2001-12-19 2010-01-06 武田薬品工業株式会社 酸素に不安定な化合物を含有する固形組成物およびその安定化方法
SI21302A (sl) * 2002-10-11 2004-04-30 LEK farmacevtska dru�ba d.d. Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino
US20050020554A1 (en) * 2003-06-06 2005-01-27 Ahmed Salah U. Stability of hormone formulations
ATE381322T1 (de) * 2003-08-05 2008-01-15 Zentiva As Verfahren zur stabilisierung von atorvastatin

Also Published As

Publication number Publication date
MX2007015431A (es) 2008-02-21
BRPI0611350B8 (pt) 2021-05-25
DE602006008942D1 (en) 2009-10-15
CA2611668A1 (en) 2006-12-21
CY1109502T1 (el) 2014-08-13
UA91051C2 (ru) 2010-06-25
HRP20090516T1 (en) 2009-10-31
WO2006135605A3 (en) 2007-04-12
CN101193633A (zh) 2008-06-04
SI1896019T1 (sl) 2010-01-29
KR20100076050A (ko) 2010-07-05
ES2330373T3 (es) 2009-12-09
US20080176893A1 (en) 2008-07-24
CA2611668C (en) 2013-10-15
WO2006135605A2 (en) 2006-12-21
MY151038A (en) 2014-03-31
EA011693B1 (ru) 2009-04-28
PE20070320A1 (es) 2007-05-12
AU2006258102B2 (en) 2011-09-15
IL187830A0 (en) 2008-04-13
EA200702670A1 (ru) 2008-04-28
JP2008543755A (ja) 2008-12-04
AU2006258102A1 (en) 2006-12-21
KR20080008413A (ko) 2008-01-23
DK1896019T3 (da) 2009-10-26
BRPI0611350A2 (pt) 2010-12-07
ECSP077984A (es) 2008-01-23
DOP2006000126A (es) 2006-12-15
CN101193633B (zh) 2011-12-14
NO20076317L (no) 2008-02-29
RS51194B (sr) 2010-10-31
EP1896019B1 (de) 2009-09-02
ZA200710697B (en) 2009-08-26
EP1896019A2 (de) 2008-03-12
BRPI0611350B1 (pt) 2020-09-15
PT1896019E (pt) 2009-11-19
NZ564003A (en) 2011-07-29
AR054283A1 (es) 2007-06-13
PL1896019T3 (pl) 2010-01-29
TNSN07466A1 (en) 2009-03-17
HK1116422A1 (en) 2008-12-24
TWI318571B (en) 2009-12-21
MA29688B1 (fr) 2008-08-01
TW200718420A (en) 2007-05-16

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