ECSP077984A - Formulacion de un inhibidor de agregacion de plaquetas de tienopiridina - Google Patents

Formulacion de un inhibidor de agregacion de plaquetas de tienopiridina

Info

Publication number
ECSP077984A
ECSP077984A EC2007007984A ECSP077984A ECSP077984A EC SP077984 A ECSP077984 A EC SP077984A EC 2007007984 A EC2007007984 A EC 2007007984A EC SP077984 A ECSP077984 A EC SP077984A EC SP077984 A ECSP077984 A EC SP077984A
Authority
EC
Ecuador
Prior art keywords
formulation
tienopiridine
aggregation inhibitor
plate aggregation
plate
Prior art date
Application number
EC2007007984A
Other languages
English (en)
Inventor
David Brian Dziennik
Tamara Beth Edelman
Peter Lloyd Oren
Robert Louis Ternik
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37198935&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP077984(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ECSP077984A publication Critical patent/ECSP077984A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La presente invención se refiere a la formulación de un compuesto de fórmula Iproceso de manufactura y métodos para usarlos.
EC2007007984A 2005-06-10 2007-12-07 Formulacion de un inhibidor de agregacion de plaquetas de tienopiridina ECSP077984A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68918305P 2005-06-10 2005-06-10

Publications (1)

Publication Number Publication Date
ECSP077984A true ECSP077984A (es) 2008-01-23

Family

ID=37198935

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2007007984A ECSP077984A (es) 2005-06-10 2007-12-07 Formulacion de un inhibidor de agregacion de plaquetas de tienopiridina

Country Status (35)

Country Link
US (1) US20080176893A1 (es)
EP (1) EP1896019B1 (es)
JP (1) JP2008543755A (es)
KR (2) KR20100076050A (es)
CN (1) CN101193633B (es)
AR (1) AR054283A1 (es)
AT (1) ATE441413T1 (es)
AU (1) AU2006258102B2 (es)
BR (1) BRPI0611350B8 (es)
CA (1) CA2611668C (es)
CY (1) CY1109502T1 (es)
DE (1) DE602006008942D1 (es)
DK (1) DK1896019T3 (es)
DO (1) DOP2006000126A (es)
EA (1) EA011693B1 (es)
EC (1) ECSP077984A (es)
ES (1) ES2330373T3 (es)
HK (1) HK1116422A1 (es)
HR (1) HRP20090516T1 (es)
IL (1) IL187830A0 (es)
MA (1) MA29688B1 (es)
MX (1) MX2007015431A (es)
MY (1) MY151038A (es)
NO (1) NO20076317L (es)
NZ (1) NZ564003A (es)
PE (1) PE20070320A1 (es)
PL (1) PL1896019T3 (es)
PT (1) PT1896019E (es)
RS (1) RS51194B (es)
SI (1) SI1896019T1 (es)
TN (1) TNSN07466A1 (es)
TW (1) TWI318571B (es)
UA (1) UA91051C2 (es)
WO (1) WO2006135605A2 (es)
ZA (1) ZA200710697B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101442862B1 (ko) * 2006-12-07 2014-09-22 다이이찌 산쿄 가부시키가이샤 만니톨 또는 유당을 함유하는 고형 제제
BRPI0719529B8 (pt) * 2006-12-07 2021-05-25 Daiichi Sankyo Co Ltd método para produzir uma preparação sólida
CA2671975C (en) * 2006-12-07 2013-10-29 Daiichi Sankyo Company, Limited Film-coated preparation having improved stability
WO2008072532A1 (ja) * 2006-12-07 2008-06-19 Daiichi Sankyo Company, Limited 貯蔵安定性が改善された医薬組成物
CA2671979C (en) * 2006-12-07 2014-02-04 Daiichi Sankyo Company, Limited Pharmaceutical composition containing low-substituted hydroxypropyl cellulose
US20100179184A1 (en) * 2006-12-07 2010-07-15 Matthew John Moon Article of manufacture for prasugrel
EP2123656B1 (en) * 2007-03-02 2014-06-11 Daiichi Sankyo Company, Limited Process for production of prasugrel hydrochloride having high purity
KR20150041173A (ko) 2007-04-27 2015-04-15 사이덱스 파마슈티칼스, 인크. 클로피도그렐 및 설포알킬 에테르 사이클로덱스트린을 함유하는 제형 및 사용 방법
GB2450117A (en) * 2007-06-13 2008-12-17 Reckitt Benckiser Healthcare A water- and oxygen-occlusive blister tablet pack
EP2257556A1 (en) 2008-02-06 2010-12-08 Helm AG Prasugrel salts with improved properties
EP2107061A1 (en) * 2008-04-02 2009-10-07 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of optically enriched clopidogrel
PL2112155T3 (pl) 2008-04-25 2011-03-31 Sandoz Ag Wodorosiarczan (VI) 2-acetoksy-5-(α-cyklopropylokarbonylo-2-fluorobenzylo)-4,5,6,7-tetrahydrotieno[3,2-c]pirydyny i sposób jego otrzymywania
EP2398468B1 (en) 2009-02-17 2016-11-30 KRKA, D.D., Novo Mesto Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation
KR101743591B1 (ko) 2009-05-13 2017-06-20 사이덱스 파마슈티칼스, 인크. 프라수그렐 및 사이클로덱스트린 유도체를 포함하는 약학 조성물 및 그의 제조 및 사용 방법
DE102009036646A1 (de) 2009-08-07 2011-02-10 Ratiopharm Gmbh Prasugrel in nicht-kristalliner Form und pharmazeutische Zusammensetzung davon
JP2013032289A (ja) * 2009-10-28 2013-02-14 Daiichi Sankyo Co Ltd ワックス安定製剤
WO2011052499A1 (ja) * 2009-10-28 2011-05-05 第一三共株式会社 貯蔵安定性が改善された医薬組成物
WO2011092720A2 (en) * 2010-02-01 2011-08-04 Msn Laboratories Limited Pharmaceutical composition of prasugrel and its pharmaceutically acceptable salts
TR201007926A1 (tr) 2010-07-19 2012-02-21 Sanovel İlaç San.Ve Ti̇c.A.Ş. Prasugrel tablet formülasyonları.
TR201006802A1 (tr) * 2010-08-17 2012-03-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Prasugrelin oral yolla dağılan formülasyonları.
TR201005900A1 (tr) 2010-07-19 2012-02-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Geliştirilmiş stabiliteye sahip prasugrel granülleri.
EP2409685A3 (en) 2010-07-19 2012-02-01 Sanovel Ilac Sanayi ve Ticaret A.S. Orally-disintegrating formulations of prasugrel
CZ2011872A3 (cs) 2011-12-22 2013-07-03 Zentiva, K.S. Farmaceutická formulace prasugrelu hydrobromidu
US8603537B2 (en) 2012-04-02 2013-12-10 Egis Pharmaceuticals Plc Prasugrel containing quickly released stable oral pharmaceutical compositions
EP2722036A1 (en) 2012-10-19 2014-04-23 Sanovel Ilac Sanayi ve Ticaret A.S. Solid oral formulations of prasugrel
EP2722037A1 (en) 2012-10-19 2014-04-23 Sanovel Ilac Sanayi ve Ticaret A.S. Prasugrel formulations
CN102993210A (zh) * 2012-12-19 2013-03-27 苏春华 一种吡啶并噻吩的新化合物
EP2979693A1 (en) 2014-08-01 2016-02-03 Zaklady Farmaceutyczne Polpharma SA Pharmaceutical composition comprising prasugrel or pharmaceutically acceptable salt thereof and process for its preparation
WO2016122421A1 (en) 2015-01-29 2016-08-04 Pharmactive Ilaç Sanayi Ve Ticaret A.Ş. Stable pharmaceutical compositions containing prasugrel base
EP3158993A1 (en) 2015-10-22 2017-04-26 Zaklady Farmaceutyczne Polpharma SA Process for preparing a tablet comprising prasugrel or pharmaceutically acceptable salt thereof
CN107304216A (zh) * 2016-04-20 2017-10-31 陕西合成药业股份有限公司 噻吩吡啶类衍生物及其制备方法和用途
HU231079B1 (hu) 2016-06-23 2020-06-29 Richter Gedeon Nyrt. Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával
GR1009230B (el) 2016-10-12 2018-02-22 Φαρματεν Αβεε Φαρμακευτικο σκευασμα που περιλαμβανει βεσυλικη πρασουγρελη

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101150B (fi) * 1991-09-09 1998-04-30 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
ES2308633T3 (es) * 2000-07-06 2008-12-01 Daiichi Sankyo Company, Limited Sal de adicion de maleato de derivados de la hidropiridina.
JP4001199B2 (ja) * 2000-07-06 2007-10-31 第一三共株式会社 ヒドロピリジン誘導体酸付加塩
EP1243524A3 (en) * 2001-03-16 2004-04-07 Pfizer Products Inc. Pharmaceutical kit for oxygen-sensitive drugs
JP4394873B2 (ja) * 2001-12-19 2010-01-06 武田薬品工業株式会社 酸素に不安定な化合物を含有する固形組成物およびその安定化方法
SI21302A (sl) * 2002-10-11 2004-04-30 LEK farmacevtska dru�ba d.d. Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino
US20050020554A1 (en) * 2003-06-06 2005-01-27 Ahmed Salah U. Stability of hormone formulations
PT1653930E (pt) * 2003-08-05 2008-03-12 Zentiva As Métodos para a estabilização da atorvastatina

Also Published As

Publication number Publication date
MA29688B1 (fr) 2008-08-01
MX2007015431A (es) 2008-02-21
NZ564003A (en) 2011-07-29
CA2611668A1 (en) 2006-12-21
RS51194B (sr) 2010-10-31
DOP2006000126A (es) 2006-12-15
JP2008543755A (ja) 2008-12-04
WO2006135605A3 (en) 2007-04-12
KR20100076050A (ko) 2010-07-05
HK1116422A1 (en) 2008-12-24
BRPI0611350B1 (pt) 2020-09-15
CN101193633A (zh) 2008-06-04
ES2330373T3 (es) 2009-12-09
EP1896019A2 (en) 2008-03-12
ATE441413T1 (de) 2009-09-15
ZA200710697B (en) 2009-08-26
AR054283A1 (es) 2007-06-13
BRPI0611350B8 (pt) 2021-05-25
UA91051C2 (ru) 2010-06-25
EA200702670A1 (ru) 2008-04-28
CA2611668C (en) 2013-10-15
DK1896019T3 (da) 2009-10-26
DE602006008942D1 (en) 2009-10-15
SI1896019T1 (sl) 2010-01-29
AU2006258102A1 (en) 2006-12-21
IL187830A0 (en) 2008-04-13
HRP20090516T1 (en) 2009-10-31
TNSN07466A1 (en) 2009-03-17
MY151038A (en) 2014-03-31
NO20076317L (no) 2008-02-29
CN101193633B (zh) 2011-12-14
CY1109502T1 (el) 2014-08-13
AU2006258102B2 (en) 2011-09-15
US20080176893A1 (en) 2008-07-24
PL1896019T3 (pl) 2010-01-29
BRPI0611350A2 (pt) 2010-12-07
PE20070320A1 (es) 2007-05-12
TW200718420A (en) 2007-05-16
WO2006135605A2 (en) 2006-12-21
EA011693B1 (ru) 2009-04-28
PT1896019E (pt) 2009-11-19
EP1896019B1 (en) 2009-09-02
TWI318571B (en) 2009-12-21
KR20080008413A (ko) 2008-01-23

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