HRP20090516T1 - Formulation of a thienopyridine platelet aggregation inhibitor - Google Patents
Formulation of a thienopyridine platelet aggregation inhibitorInfo
- Publication number
- HRP20090516T1 HRP20090516T1 HR20090516T HRP20090516T HRP20090516T1 HR P20090516 T1 HRP20090516 T1 HR P20090516T1 HR 20090516 T HR20090516 T HR 20090516T HR P20090516 T HRP20090516 T HR P20090516T HR P20090516 T1 HRP20090516 T1 HR P20090516T1
- Authority
- HR
- Croatia
- Prior art keywords
- formulation
- platelet aggregation
- aggregation inhibitor
- thienopyridine
- thienopyridine platelet
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 101000783577 Dendroaspis angusticeps Thrombostatin Proteins 0.000 title 1
- 101000783578 Dendroaspis jamesoni kaimosae Dendroaspin Proteins 0.000 title 1
- 229940127218 antiplatelet drug Drugs 0.000 title 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 title 1
- DBDCNCCRPKTRSD-UHFFFAOYSA-N thieno[3,2-b]pyridine Chemical compound C1=CC=C2SC=CC2=N1 DBDCNCCRPKTRSD-UHFFFAOYSA-N 0.000 title 1
- 229940125670 thienopyridine Drugs 0.000 title 1
- 239000002175 thienopyridine Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000011261 inert gas Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68918305P | 2005-06-10 | 2005-06-10 | |
| PCT/US2006/021860 WO2006135605A2 (en) | 2005-06-10 | 2006-06-06 | Formulation of a thienopyridine platelet aggregation inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090516T1 true HRP20090516T1 (en) | 2009-10-31 |
Family
ID=37198935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090516T HRP20090516T1 (en) | 2005-06-10 | 2009-09-25 | Formulation of a thienopyridine platelet aggregation inhibitor |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US20080176893A1 (es) |
| EP (1) | EP1896019B1 (es) |
| JP (1) | JP2008543755A (es) |
| KR (2) | KR20080008413A (es) |
| CN (1) | CN101193633B (es) |
| AR (1) | AR054283A1 (es) |
| AT (1) | ATE441413T1 (es) |
| AU (1) | AU2006258102B2 (es) |
| BR (1) | BRPI0611350B8 (es) |
| CA (1) | CA2611668C (es) |
| CY (1) | CY1109502T1 (es) |
| DE (1) | DE602006008942D1 (es) |
| DK (1) | DK1896019T3 (es) |
| DO (1) | DOP2006000126A (es) |
| EA (1) | EA011693B1 (es) |
| EC (1) | ECSP077984A (es) |
| ES (1) | ES2330373T3 (es) |
| HK (1) | HK1116422A1 (es) |
| HR (1) | HRP20090516T1 (es) |
| IL (1) | IL187830A0 (es) |
| MA (1) | MA29688B1 (es) |
| MX (1) | MX2007015431A (es) |
| MY (1) | MY151038A (es) |
| NO (1) | NO20076317L (es) |
| NZ (1) | NZ564003A (es) |
| PE (1) | PE20070320A1 (es) |
| PL (1) | PL1896019T3 (es) |
| PT (1) | PT1896019E (es) |
| RS (1) | RS51194B (es) |
| SI (1) | SI1896019T1 (es) |
| TN (1) | TNSN07466A1 (es) |
| TW (1) | TWI318571B (es) |
| UA (1) | UA91051C2 (es) |
| WO (1) | WO2006135605A2 (es) |
| ZA (1) | ZA200710697B (es) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5289975B2 (ja) * | 2006-12-07 | 2013-09-11 | 第一三共株式会社 | マンニトール又は乳糖を含有する固形製剤 |
| WO2008072535A1 (ja) * | 2006-12-07 | 2008-06-19 | Daiichi Sankyo Company, Limited | 低置換度ヒドロキシプロピルセルロースを含有する医薬組成物 |
| TWI405591B (zh) * | 2006-12-07 | 2013-08-21 | Daiichi Sankyo Co Ltd | 固形製劑之製造方法 |
| US20100280064A1 (en) * | 2006-12-07 | 2010-11-04 | Tomoyuki Watanabe | Pharmaceutical composition having improved storage stability |
| EP2100606A4 (en) * | 2006-12-07 | 2009-12-30 | Daiichi Sankyo Co Ltd | COATED PREPARATION OF A FILM HAVING IMPROVED STABILITY |
| AU2007333302A1 (en) * | 2006-12-07 | 2008-06-19 | Eli Lilly And Company | An article comprising prasugrel |
| MX2009009413A (es) * | 2007-03-02 | 2009-09-11 | Daiichi Sankyo Co Ltd | Metodo para la produccion de clorhidrato de prasugrel de alta pureza. |
| RU2470636C2 (ru) | 2007-04-27 | 2012-12-27 | Сайдекс Фамэсьютиклз, Инк. | Композиция клопидогреля и сульфоалкилового эфира циклодекстрина (варианты) и способы лечения заболеваний посредством названной композиции (варианты) |
| GB2450117A (en) * | 2007-06-13 | 2008-12-17 | Reckitt Benckiser Healthcare | A water- and oxygen-occlusive blister tablet pack |
| EP2257556A1 (en) * | 2008-02-06 | 2010-12-08 | Helm AG | Prasugrel salts with improved properties |
| EP2107061A1 (en) * | 2008-04-02 | 2009-10-07 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of optically enriched clopidogrel |
| DE602008002820D1 (de) | 2008-04-25 | 2010-11-11 | Sandoz Ag | Hydrogensulfat von 2-Acetoxy-5-(a-cyclopropylcarbonyl-2-fluorbenzyl)-4,5,6,7-tetrahydrothienoÄ3,2-cÜpyridin und dessen Zubereitung |
| WO2010094471A1 (en) * | 2009-02-17 | 2010-08-26 | Krka, D. D., Novo Mesto | Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation |
| PT3100728T (pt) | 2009-05-13 | 2020-02-21 | Cydex Pharmaceuticals Inc | Composições farmacêuticas que compreendem prasugrel e derivados da ciclodextrina e métodos de produção e utilização dos mesmos |
| DE102009036646A1 (de) | 2009-08-07 | 2011-02-10 | Ratiopharm Gmbh | Prasugrel in nicht-kristalliner Form und pharmazeutische Zusammensetzung davon |
| WO2011052499A1 (ja) * | 2009-10-28 | 2011-05-05 | 第一三共株式会社 | 貯蔵安定性が改善された医薬組成物 |
| JP2013032289A (ja) * | 2009-10-28 | 2013-02-14 | Daiichi Sankyo Co Ltd | ワックス安定製剤 |
| WO2011092720A2 (en) * | 2010-02-01 | 2011-08-04 | Msn Laboratories Limited | Pharmaceutical composition of prasugrel and its pharmaceutically acceptable salts |
| TR201005900A1 (tr) | 2010-07-19 | 2012-02-21 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Geliştirilmiş stabiliteye sahip prasugrel granülleri. |
| EP2409685A3 (en) | 2010-07-19 | 2012-02-01 | Sanovel Ilac Sanayi ve Ticaret A.S. | Orally-disintegrating formulations of prasugrel |
| TR201006802A1 (tr) * | 2010-08-17 | 2012-03-21 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Prasugrelin oral yolla dağılan formülasyonları. |
| TR201007926A1 (tr) | 2010-07-19 | 2012-02-21 | Sanovel İlaç San.Ve Ti̇c.A.Ş. | Prasugrel tablet formülasyonları. |
| CZ2011872A3 (cs) | 2011-12-22 | 2013-07-03 | Zentiva, K.S. | Farmaceutická formulace prasugrelu hydrobromidu |
| US8603537B2 (en) | 2012-04-02 | 2013-12-10 | Egis Pharmaceuticals Plc | Prasugrel containing quickly released stable oral pharmaceutical compositions |
| WO2014060560A1 (en) | 2012-10-19 | 2014-04-24 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Solid oral formulations of prasugrel |
| EP2722037A1 (en) | 2012-10-19 | 2014-04-23 | Sanovel Ilac Sanayi ve Ticaret A.S. | Prasugrel formulations |
| CN102993210A (zh) * | 2012-12-19 | 2013-03-27 | 苏春华 | 一种吡啶并噻吩的新化合物 |
| EP2979693A1 (en) | 2014-08-01 | 2016-02-03 | Zaklady Farmaceutyczne Polpharma SA | Pharmaceutical composition comprising prasugrel or pharmaceutically acceptable salt thereof and process for its preparation |
| WO2016122421A1 (en) | 2015-01-29 | 2016-08-04 | Pharmactive Ilaç Sanayi Ve Ticaret A.Ş. | Stable pharmaceutical compositions containing prasugrel base |
| EP3158993A1 (en) | 2015-10-22 | 2017-04-26 | Zaklady Farmaceutyczne Polpharma SA | Process for preparing a tablet comprising prasugrel or pharmaceutically acceptable salt thereof |
| CN107304216A (zh) * | 2016-04-20 | 2017-10-31 | 陕西合成药业股份有限公司 | 噻吩吡啶类衍生物及其制备方法和用途 |
| HU231079B1 (hu) | 2016-06-23 | 2020-06-29 | Richter Gedeon Nyrt. | Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával |
| GR1009230B (el) | 2016-10-12 | 2018-02-22 | Φαρματεν Αβεε | Φαρμακευτικο σκευασμα που περιλαμβανει βεσυλικη πρασουγρελη |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI101150B (fi) * | 1991-09-09 | 1998-04-30 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi |
| PT1728794E (pt) * | 2000-07-06 | 2008-07-15 | Ube Industries | Sal de adição maleato de derivados de hidropiridina |
| JP4001199B2 (ja) * | 2000-07-06 | 2007-10-31 | 第一三共株式会社 | ヒドロピリジン誘導体酸付加塩 |
| EP1243524A3 (en) * | 2001-03-16 | 2004-04-07 | Pfizer Products Inc. | Pharmaceutical kit for oxygen-sensitive drugs |
| JP4394873B2 (ja) * | 2001-12-19 | 2010-01-06 | 武田薬品工業株式会社 | 酸素に不安定な化合物を含有する固形組成物およびその安定化方法 |
| SI21302A (sl) * | 2002-10-11 | 2004-04-30 | LEK farmacevtska dru�ba d.d. | Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino |
| US20050020554A1 (en) * | 2003-06-06 | 2005-01-27 | Ahmed Salah U. | Stability of hormone formulations |
| EP1653930B1 (en) * | 2003-08-05 | 2007-12-19 | Zentiva, a.s. | Methods for the stabilization of atorvastatin |
-
2006
- 2006-06-02 TW TW095119687A patent/TWI318571B/zh active
- 2006-06-06 AT AT06772240T patent/ATE441413T1/de active
- 2006-06-06 DE DE602006008942T patent/DE602006008942D1/de active Active
- 2006-06-06 PL PL06772240T patent/PL1896019T3/pl unknown
- 2006-06-06 JP JP2008515813A patent/JP2008543755A/ja active Pending
- 2006-06-06 US US11/913,889 patent/US20080176893A1/en not_active Abandoned
- 2006-06-06 SI SI200630490T patent/SI1896019T1/sl unknown
- 2006-06-06 NZ NZ564003A patent/NZ564003A/en not_active IP Right Cessation
- 2006-06-06 PT PT06772240T patent/PT1896019E/pt unknown
- 2006-06-06 RS RSP-2009/0425A patent/RS51194B/sr unknown
- 2006-06-06 MX MX2007015431A patent/MX2007015431A/es active IP Right Grant
- 2006-06-06 KR KR1020077028749A patent/KR20080008413A/ko not_active Application Discontinuation
- 2006-06-06 KR KR1020107011742A patent/KR20100076050A/ko not_active Application Discontinuation
- 2006-06-06 UA UAA200712993A patent/UA91051C2/ru unknown
- 2006-06-06 AU AU2006258102A patent/AU2006258102B2/en not_active Ceased
- 2006-06-06 BR BRPI0611350A patent/BRPI0611350B8/pt active IP Right Grant
- 2006-06-06 WO PCT/US2006/021860 patent/WO2006135605A2/en active Application Filing
- 2006-06-06 DK DK06772240T patent/DK1896019T3/da active
- 2006-06-06 EP EP06772240A patent/EP1896019B1/en not_active Revoked
- 2006-06-06 EA EA200702670A patent/EA011693B1/ru not_active IP Right Cessation
- 2006-06-06 CN CN2006800205289A patent/CN101193633B/zh active Active
- 2006-06-06 DO DO2006000126A patent/DOP2006000126A/es unknown
- 2006-06-06 CA CA2611668A patent/CA2611668C/en not_active Expired - Fee Related
- 2006-06-06 ES ES06772240T patent/ES2330373T3/es active Active
- 2006-06-08 PE PE2006000641A patent/PE20070320A1/es not_active Application Discontinuation
- 2006-06-09 AR AR20060102430A patent/AR054283A1/es unknown
- 2006-06-09 MY MYPI20062708 patent/MY151038A/en unknown
-
2007
- 2007-12-03 IL IL187830A patent/IL187830A0/en unknown
- 2007-12-07 TN TNP2007000466A patent/TNSN07466A1/en unknown
- 2007-12-07 ZA ZA200710697A patent/ZA200710697B/xx unknown
- 2007-12-07 EC EC2007007984A patent/ECSP077984A/es unknown
- 2007-12-07 NO NO20076317A patent/NO20076317L/no not_active Application Discontinuation
-
2008
- 2008-01-09 MA MA30568A patent/MA29688B1/fr unknown
- 2008-06-20 HK HK08106909.9A patent/HK1116422A1/xx not_active IP Right Cessation
-
2009
- 2009-09-25 HR HR20090516T patent/HRP20090516T1/xx unknown
- 2009-10-22 CY CY20091101101T patent/CY1109502T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20090516T1 (en) | Formulation of a thienopyridine platelet aggregation inhibitor | |
| AR052853A1 (es) | Composiciones orales que contienen compuestos antibacterianos de bifenol | |
| EP3586631A3 (en) | Plant health composition | |
| DK1848659T3 (da) | Oxygenopfangningssammensætninger og emballage omfattende sammensætningerne | |
| TR201908611T4 (tr) | Hububatta mantarla mücadeleye yönelik epoksikonazol içeren sinerjistik fungisidal karışımlar. | |
| RS52169B (en) | STABLE LAKVINIMOD PREPARATIONS | |
| EA200801859A1 (ru) | Неводная композиция стабильного витамина "c", способ ее приготовления и применения | |
| ECSP088294A (es) | Formulación en aerosol para la inhalación de beta-agonistas | |
| WO2008049042A3 (en) | Ophthalmic compositions containing diglycine | |
| CY1122084T1 (el) | Συνθεσεις που περιλαμβανουν αμλοδιπινη και μπισοπρολολη | |
| UY30543A1 (es) | Formulacion de aerosol para la inhalacion de beta- agonistas | |
| NO20085317L (no) | Imidazoazepinonforbindelser | |
| MX337380B (es) | Composiciones pesticidas. | |
| AR046254A1 (es) | Productos farmaceuticos estables | |
| FR2893924B1 (fr) | Paquet d'articles comprenant un flanc le recouvrant partiellement et un film enveloppant le tout. | |
| SV2006002238A (es) | Inhibidores de la adenilato ciclasa soluble ref. p-sv-78. 959/gh | |
| CR10690A (es) | Nuevos derivados de fluoreno, composiciones que los contienen y utilizacion como inhibidores de la proteina chaperona hsp90 | |
| MA31678B1 (fr) | Composition therapeutique aromatisee a base d'argile | |
| EA200801139A1 (ru) | Композиция для аэрозольной ингаляции | |
| EA200700689A1 (ru) | Сохраняющая свежесть упаковка для удлиненных изделий | |
| SG163490A1 (en) | Packaging body | |
| ATE324869T1 (de) | Blisterverpackung und feste dosierungsform enthaltend desmopressin | |
| PA8593701A1 (es) | [4-(3-aminometilfenil)piperidin-1-il]-[5-(2-fluorofenil-etinil)furan-2-il]-metanoma como inhibidor de triptasa de mastocitos | |
| TH87282B (th) | สูตรผสมของสารยับยั้งการรวมกลุ่มของเกล็ดเลือดชนิดไทอีโนไพริดีน | |
| GEP20084546B (en) | Novel association consisting of an anti-atherothrombotic agent and of platelet antiaggregating agent |